Test sample devices and methods
    43.
    发明授权

    公开(公告)号:US11278889B2

    公开(公告)日:2022-03-22

    申请号:US16616944

    申请日:2017-07-18

    Abstract: A sample test device is provided that includes a body having an insertion surface spaced apart from a distal end portion and a fluid manipulating assembly disposed in the distal end portion. A mixing receptacle is defined in the fluid manipulating assembly and provides a volume to mix a test mixture. A plunger is disposed in the body and creates a positive air pressure in the mixing receptacle when inserted into the body. A test die is disposed in the fluid manipulation assembly and a fluid path extends from the mixing receptacle to the test die. Activation of the plunger creates a positive pressure in the mixing receptacle to force the test mixture to flow from the mixing receptacle to the test die.

    MICROFLUIDIC PARTICLE CONCENTRATORS

    公开(公告)号:US20220080422A1

    公开(公告)日:2022-03-17

    申请号:US17417615

    申请日:2019-02-12

    Abstract: The present disclosure relates to a microfluidic particle concentrator that includes an inlet microchannel, a filtering chamber fluidly connected to the inlet microchannel to receive a sample fluid, and a mechanical filter positioned in the filtering chamber. The particle concentrator also includes a filter outlet microchannel fluidly connected to the filtering chamber to receive a particle-ablated fluid formed by passing through the mechanical filter, a particle outlet microchannel fluidly connected to the filtering chamber to receive a particle-concentrated fluid including a plurality of particles not permitted to pass through the mechanical filter, and a fluid movement network including multiple pumps. The multiple fluid pumps generate sample fluid flow through the inlet microchannel and into the filtering chamber, particle-ablated fluid flow from the mechanical filter into the filter outlet microchannel, and particle-concentrated fluid from the filtering chamber into the particle outlet microchannel.

    CELL ANALYZERS
    45.
    发明申请

    公开(公告)号:US20220080421A1

    公开(公告)日:2022-03-17

    申请号:US17414155

    申请日:2019-05-13

    Abstract: A system includes a microchannel analysis region, a first fluid actuation device, a second fluid actuation device, a sensor, and a controller. The first fluid actuation device is at a first end of the microchannel analysis region. The second fluid actuation device is at a second end of the microchannel analysis region opposite to the first end. The sensor is within the microchannel analysis region between the first fluid actuation device and the second fluid actuation device. The sensor measures an impedance of a fluid within the microchannel analysis region. The controller activates the first fluid actuation device to generate a first pressure wave in the fluid and activates the second fluid actuation device to generate a second pressure wave in the fluid. The first pressure wave and the second pressure wave converge at the sensor.

    FLUID IDENTIFICATION VIA ELECTROCHEMICAL LABELS

    公开(公告)号:US20220065815A1

    公开(公告)日:2022-03-03

    申请号:US17415388

    申请日:2019-05-07

    Abstract: In one example in accordance with the present disclosure, a fluid analysis device is described. The fluid analysis device includes a chamber to receive a number of fluids. At least one fluid includes an electrochemical label with a unique electrochemical response to an applied electrical potential. A multi-electrode sensor of the fluid analysis device is disposed within the chamber and detects electrical signals within the chamber. The fluid analysis device also includes a controller coupled to the multi-electrode sensor. The controller applies an electrical potential across multiple electrodes of the multi-electrode sensor and identifies, from the electrical signal detected by the multi-electrode sensor, fluids currently in the chamber based on the unique electrochemical responses of associated electrochemical labels.

    MICROFLUIDIC PRESSURE SENSOR
    49.
    发明申请

    公开(公告)号:US20210190616A1

    公开(公告)日:2021-06-24

    申请号:US16074349

    申请日:2016-04-20

    Abstract: A microfluidic pressure sensor may include a reference chamber, a sensed volume, a microfluidic channel connecting an interior of the reference chamber to an interior of the sensed volume, a volume of liquid contained and movable within the microfluidic channel while occluding the microfluidic channel and a sensor to output signals indicating positioning of the volume of liquid along the microfluidic channel. Positioning of the volume of liquid along microfluidic channel indicates a pressure of the sensed volume.

    MICROFLUIDIC DEVICES
    50.
    发明申请

    公开(公告)号:US20210031192A1

    公开(公告)日:2021-02-04

    申请号:US16768857

    申请日:2018-03-12

    Abstract: A microfluidic device may include a die package. The die package may include at least on fluidic die and an overmold material overmolding the fluidic die. The microfluidic device may also include a mesofluidic plate coupled to the die package. The mesofluidic plate includes at least one mesofluidic channel formed therein to fluidically couple the fluidic die.

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