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217 条记录 (耗时 0.053 秒)

    Tablet production method and tablet production apparatus
    44.
    发明申请
    Tablet production method and tablet production apparatus 有权
    片剂生产方法及片剂生产设备

    公开(公告)号：US20080031989A1

    公开(公告)日：2008-02-07

    申请号：US11808619

    申请日：2007-06-12

    申请人： Yasushi Watanabe ,  Kimiaki Hayakawa ,  Eiichiro Hirota ,  Kiyoshi Morimoto

    发明人： Yasushi Watanabe ,  Kimiaki Hayakawa ,  Eiichiro Hirota ,  Kiyoshi Morimoto

    IPC分类号： A61K9/20

    CPC分类号： C04B41/009 ,  A61J3/10 ,  B01J2/00 ,  B01J2/16 ,  B01J2/22 ,  B30B15/0011 ,  C04B41/5022 ,  C04B2111/00836 ,  C04B41/4523 ,  C04B35/10 ,  C04B35/119 ,  C04B35/443 ,  C04B35/447

    摘要： A tablet production apparatus comprising a gas generator G, a lubricant powder discharge means 51 for discharging a lubricant powder into a gas generated from the gas generator G, depending on the supply of the gas from the gas generator G, and mixing the lubricant powder with the gas in dispersed state, a lubricant application means 91 for spraying the lubricant powder discharged from the lubricant powder discharge means 51 and mixed with the gas generated from the gas generation means G in dispersed state, onto each material contacting surface of a die, an upper punch and a lower punch, and an oxygen concentration measuring means 131a for measuring the oxygen concentration of the gas existing near the lubricant application means 91. The apparatus is designed such that the amount of the gas supplied into the lubricant application means is adjusted based on the oxygen concentration measured by the oxygen concentration measuring means 131a.

    摘要翻译： 一种片剂生产设备，包括气体发生器G，润滑剂粉末排出装置51，用于根据来自气体发生器G的气体的供应将润滑剂粉末排放到由气体发生器G产生的气体中，并将​​润滑剂粉末与 分散状态的气体，用于喷射从润滑剂粉末排出装置51排出的润滑剂粉末并将其与分散状态的气体产生装置G产生的气体混合的润滑剂施加装置91到模具的每个材料接触表面上 上冲头和下冲头，以及用于测量存在于润滑剂施加装置91附近的气体的氧浓度的氧浓度测量装置131a。 该设备被设计成使得根据由氧浓度测量装置131a测量的氧浓度来调节供应到润滑剂施加装置中的气体的量。

    Indanol derivative
    45.
    发明申请
    Indanol derivative 失效
    吲哚衍生物

    公开(公告)号：US20070197570A1

    公开(公告)日：2007-08-23

    申请号：US10590305

    申请日：2005-02-24

    申请人： Takahide Nishi ,  Toshiyasu Takemoto ,  Takuya Ikeda ,  Kiyoshi Morimoto

    发明人： Takahide Nishi ,  Toshiyasu Takemoto ,  Takuya Ikeda ,  Kiyoshi Morimoto

    IPC分类号： A61K31/435

    CPC分类号： C07D413/06 ,  C07D413/14

    摘要： The present invention provides a compound having the following general formula (I) which is useful as a neurokinin receptor antagonist: (wherein, R1, R2: optionally substituted (hetero)aryl, R3: —CO—R4, —CO—O—R4, etc., R4: alkyl, cycloalkyl, etc., A: CH2, CO, SO2, B: a single bond, etc., D: oxygen, CH2, E: alkylene, alkenylene, n: 1 to 3).

    摘要翻译： 本发明提供具有以下通式（I）的化合物，其可用作神经激肽受体拮抗剂：（其中R 1，R 2，R 2）：任选取代的 ）芳基，R 3：-CO-R 4，-CO-OR 4等，R 4 O >：烷基，环烷基等，A：CH 2，CO，SO 2，B：单键等，D：氧，CH 2，E：亚烷基，亚烯基，n：1至3）。

    Coating device for powder material
    46.
    发明授权
    Coating device for powder material 有权
    粉末涂料装置

    公开(公告)号：US07131828B2

    公开(公告)日：2006-11-07

    申请号：US10257068

    申请日：2001-04-12

    申请人： Yasushi Watanabe ,  Kiyoshi Morimoto ,  Yuji Iwase ,  Satoru Hiruta

    发明人： Yasushi Watanabe ,  Kiyoshi Morimoto ,  Yuji Iwase ,  Satoru Hiruta

    IPC分类号： B29C33/60 ,  B29C43/28

    CPC分类号： B30B11/08 ,  B30B15/0011 ,  Y10T83/9423

    摘要： A powder material application apparatus capable of applying powder material uniformly onto lower surfaces of plural upper punches, upper surfaces of plural lower punches and inner circumferences of plural dies of a tabletting machine. Powder material is applied on a material contacting surface of the lower punch by spraying powder material mixed with air from a powder material spray port for lower punch of a powder material application part for lower punch. Powder material is applied on a material contacting surface of the upper punch wherein powder material is not applied enough according to gravity by spraying powder material mixed with air from a powder material spray port for upper punch while the upper punch moves from an initial end to a terminal end of the powder material spray port for upper punch. The powder material spray port for upper punch is provided along the rotary orbit of the upper punches and is elongated more than the powder material spray port for lower punch.

    摘要翻译： 一种粉末材料施加装置，其能够将粉末材料均匀地施加到多个上冲头的下表面，多个下冲头的上表面和压片机的多个模具的内周。 粉末材料通过喷射与空气混合的粉末材料施加在下冲头的材料接触表面上，粉末材料喷雾口用于下冲头的粉末材料施加部件的下冲头。 将粉末材料施加在上冲头的材料接触表面上，其中粉末材料根据重力不能充分施加，喷射与来自上冲头的粉末材料喷雾口的空气混合的粉末材料，同时上冲头从初始端移动到 粉末末端末端用于上冲头喷雾口。 上冲头的粉料喷射口沿着上冲头的旋转轨道设置，并且比用于下冲头的粉末喷射口更细。

    Silver halide photographic lightsensitive material
    48.
    发明授权
    Silver halide photographic lightsensitive material 失效
    卤化银照相感光材料

    公开(公告)号：US06924091B2

    公开(公告)日：2005-08-02

    申请号：US10034607

    申请日：2002-01-03

    申请人： Yoichi Hosoya ,  Kiyoshi Morimoto ,  Tadashi Inaba

    发明人： Yoichi Hosoya ,  Kiyoshi Morimoto ,  Tadashi Inaba

    IPC分类号： G03C1/005 ,  G03C1/10 ,  G03C1/34 ,  G03C1/38 ,  G03C7/30 ,  G03C7/305 ,  G03C7/388 ,  G03C7/392 ,  G03C1/08 ,  G03C7/26 ,  G03C7/32

    CPC分类号： G03C7/30541 ,  G03C1/0051 ,  G03C1/0053 ,  G03C1/10 ,  G03C1/34 ,  G03C1/38 ,  G03C7/3003 ,  G03C7/3022 ,  G03C7/3885 ,  G03C7/392 ,  G03C2001/0056 ,  G03C2001/03552 ,  G03C2200/03 ,  G03C2200/24 ,  Y10S430/156 ,  Y10S430/158

    摘要： A silver halide photographic lightsensitive material comprising a support having thereon at least one lightsensitive silver halide emulsion layer, wherein the lightsensitive material contains at least one compound represented by general formula (I) and at least one photographically useful group-releasing compound represented by general formula (II) or (III) that is capable of forming a compound having substantially no contribution to a dye after its coupling with an oxidized form of a developing agent: (X)k—(L)m—(A—B)n  (I) COUP1—D1  (II) COUP2—C—E—D2  (III) The definitions of the substituents are set forth in the specification.

    摘要翻译： 一种卤化银照相感光材料，其包括其上具有至少一种感光卤化银乳剂层的载体，其中所述光敏材料含有至少一种由通式（I）表示的化合物和至少一种由通式 （II）或（III），其能够在与显影剂的氧化形式偶联之后形成对染料基本上没有贡献的化合物：<？in-line-formula description =“In-line Formulas”end = （X）k-（L）m-（AB）n（I）<？in-line-formula description =“In-line Formulas”end =“tail”？> <？in-line- 公式描述=“内联公式”end =“lead”？> COUP1-D1（II）<？in-line-formula description =“In-line Formulas”end =“tail”？> <？in-line- 公式描述=“在线公式”end =“lead”？> COUP2-CE-D2（III）<？in-line-formula description =“In-line Formulas”end =“tail”？> 取代基在规定中列出 ication。

    Tablets quickly disintegrating in oral cavity
    49.
    发明申请
    Tablets quickly disintegrating in oral cavity 审中-公开
    片剂在口腔内迅速崩解

    公开(公告)号：US20050147666A1

    公开(公告)日：2005-07-07

    申请号：US10506349

    申请日：2003-03-06

    申请人： Motohiro Ohta ,  Yuji Iwase ,  Naohiro Saito ,  Kiyoshi Morimoto

    发明人： Motohiro Ohta ,  Yuji Iwase ,  Naohiro Saito ,  Kiyoshi Morimoto

    IPC分类号： A61K9/00 ,  A61K9/20 ,  A61K31/22 ,  A61P3/06

    CPC分类号： A61K31/22 ,  A61K9/0056 ,  A61K9/2018

    摘要： According to the present invention, provided are an intraorally rapidly disintegrable tablet which comprises D-mannitol and a disintegrator in addition to fine granules prepared by granulating a mixture of a water-soluble pharmacologically active ingredient and an adsorbent; a process for producing an intraorally rapidly disintegrable tablet which comprises mixing D-mannitol and a disintegrator with fine granules prepared by granulating a mixture of a water-soluble pharmacologically active ingredient and an adsorbent to yield a material for compression molding, and subjecting the material to compression molding; and an intraorally rapidly disintegrable tablet which is prepared by mixing D-mannitol and a disintegrator with fine granules prepared by granulating a mixture of a water-soluble pharmacologically active ingredient and an adsorbent to yield a material for compression molding, subjecting the material to compression molding.

    摘要翻译： 根据本发明，提供了除了通过将水溶性药理活性成分和吸附剂的混合物制粒而制备的细颗粒以外还含有D-甘露糖醇和崩解剂的口腔内快速崩解片剂， 一种生产口腔内快速崩解片剂的方法，其包括将D-甘露糖醇和崩解剂与通过将水溶性药理学活性成分和吸附剂的混合物制粒而制备的细粒混合，得到压缩成型材料， 压缩成型; 以及通过将D-甘露糖醇和崩解剂与通过将水溶性药理活性成分和吸附剂的混合物制粒而制备的细颗粒混合而制备的口腔内快速崩解片剂，得到压缩成型材料，将其压缩成型 。