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41.发明申请公开(公告)号：US20140276046A1
公开(公告)日：2014-09-18
申请号：US13801400
申请日：2013-03-13
CPC分类号： A61B8/485 , A61B8/08 , A61B8/463 , A61B8/488 , A61B8/5223 , A61B8/5269 , G01S7/52042 , G01S7/52071 , G01S15/8915 , G01S15/8979
摘要： In ARFI imaging, a cost function is used to identify a time of displacement that best or sufficiently indicates the desired information. For example, the displacements associated with a combination of contrast and signal-to-noise ratio are identified. The time at which the desired displacements occur may be other than the time of the maximum. Since the time is common to displacements for one or more scan lines, the displacement image may be assembled line-by-line or by groups of lines.
摘要翻译： 在ARFI成像中，使用成本函数来识别最佳或充分指示所需信息的位移时间。 例如，识别与对比度和信噪比的组合相关联的位移。 期望位移发生的时间可以不是最大值的时间。 由于时间对于一个或多个扫描线的位移是常见的，所以位移图像可以逐行或由一组线组合。
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公开(公告)号：US08187187B2
公开(公告)日：2012-05-29
申请号：US12174011
申请日：2008-07-16
IPC分类号： A61B8/00
CPC分类号： A61B8/00 , A61B8/463 , A61B8/485 , G01S7/52042
摘要： Shear wave imaging is provided in medical diagnostic ultrasound. A region is imaged to determine a location in which to calculate shear velocity. The shear velocity is estimated for the location. The imaging may guide the identification of the location, reducing the time to determine useful shear information. The estimate of shear may be validated, such as using cross-validation, to indicate the confidence level of the shear value. The shear velocity may be displayed relative to a scale of shear velocities associated with a type of tissue, such as tissue for an organ. The location on a scale may be more intuitive for a user.
摘要翻译： 医学诊断超声波提供剪切波成像。 成像一个区域以确定计算剪切速度的位置。 估计剪切速度的位置。 成像可以指导位置的识别，减少确定有用剪切信息的时间。 可以验证剪切的估计，例如使用交叉验证来指示剪切值的置信水平。 剪切速度可以相对于与一种类型的组织（例如器官的组织）相关联的剪切速度的尺度显示。 比例尺上的位置对用户来说可能更直观。
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43.发明申请Tissue Density Quantification Using Shear Wave Information in Medical Ultrasound Scanning 有权医学超声扫描中使用剪切波信息的组织密度定量公开(公告)号：US20120108968A1
公开(公告)日：2012-05-03
申请号：US12913599
申请日：2010-10-27
申请人： Paul Freiburger , Liexiang Fan , Roee Lazebnik
发明人： Paul Freiburger , Liexiang Fan , Roee Lazebnik
IPC分类号： A61B8/00
CPC分类号： A61B8/0825 , A61B8/485 , A61B8/5223 , G01S7/52042
摘要： Tissue density is quantified using shear wave information in medical ultrasound scanning. Measurements of the tissue reaction to shear waves indicate tissue density. For example, shear wave velocity is linked with density using clinical study information. The shear wave velocity in a region, over the entire tissue, or at various locations is used to determine a corresponding density or densities. The tissue density information is used for categorization, estimation of disease risk, imaging, diagnosis, or other uses. The tissue may be breast tissue or other tissue.
摘要翻译： 在医学超声扫描中使用剪切波信息量化组织密度。 对剪切波的组织反应的测量表明组织密度。 例如，使用临床研究信息，剪切波速度与密度相关。 使用在整个组织或各个位置的区域中的剪切波速度来确定相应的密度或密度。 组织密度信息用于分类，估计疾病风险，成像，诊断或其他用途。 组织可以是乳房组织或其他组织。
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公开(公告)号：US20120089019A1
公开(公告)日：2012-04-12
申请号：US12898957
申请日：2010-10-06
申请人： Liexiang Fan
发明人： Liexiang Fan
IPC分类号： A61B8/00
CPC分类号： A61B8/485 , A61B8/14 , A61B8/488 , G01S7/52042 , G01S15/8906 , G06F19/00
摘要： A shear wave velocity solution is provided for medical ultrasound imaging. Rather than determining shear wave information for each location based on distance from the origin of the shear wave and time to peak displacement for the location, displacement profiles resulting from different combinations of origin and detection locations are correlated. Shear information is detected using displacements from a diverse spatial combination of transmission locations and detection locations. The correlation combination is used in a same function for simultaneously solving for the delays for multiple lateral locations. Spatial diversity and layered correlation may provide for more accurate shear wave estimation.
摘要翻译： 提供用于医学超声成像的剪切波速度解决方案。 与根据距离原始的剪切波的距离以及位置的时间到峰值位移的距离确定每个位置的剪切波信息而不是根据不同原点和检测位置的组合产生的位移曲线相关。 使用来自传输位置和检测位置的不同空间组合的位移来检测剪切信息。 相关组合用于相同的功能，用于同时求解多个横向位置的延迟。 空间分集和分层相关可以提供更准确的剪切波估计。
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公开(公告)号：US20110060221A1
公开(公告)日：2011-03-10
申请号：US12554749
申请日：2009-09-04
申请人： Liexiang Fan , Kevin Sekins
发明人： Liexiang Fan , Kevin Sekins
IPC分类号： A61B8/00
CPC分类号： A61B8/00 , A61B5/015 , A61B8/5223 , A61B2017/00084 , A61B2017/00106 , A61B2018/00577 , A61B2018/00702 , A61B2018/00773 , A61B2018/00791 , A61B2090/378 , A61N7/02
摘要： Temperature related information or a temperature characteristic is detected, at least in part, with a medical diagnostic ultrasound system. Anatomy information from an ultrasound scan is used with modeling to determine the temperature or other temperature related parameter. Ultrasound information may be obtained in real-time with application of thermal therapy, so may be used to better control thermal treatment. The anatomy information may be used to align model features measured from a region. The anatomy information may be used as an input into the model. The anatomy information may be used to select an appropriate model, such as selection based on the type of tissue. The anatomy information may be used to correct an output of the model, such as accounting for temperature distribution due to an adjacent vessel.
摘要翻译： 至少部分地利用医疗诊断超声系统检测温度相关信息或温度特性。 使用来自超声波扫描的解剖信息进行建模以确定温度或其他与温度相关的参数。 应用热疗可以实时获取超声信息，因此可用于更好地控制热处理。 解剖信息可用于对准从区域测量的模型特征。 解剖信息可以用作模型中的输入。 解剖信息可用于选择适当的模型，例如基于组织类型的选择。 可以使用解剖信息来校正模型的输出，例如考虑由于邻近的血管造成的温度分布。
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46.发明申请公开(公告)号：US20100317971A1
公开(公告)日：2010-12-16
申请号：US12869280
申请日：2010-08-26
申请人： Liexiang Fan , Kevin Sekins
发明人： Liexiang Fan , Kevin Sekins
CPC分类号： A61N7/02 , A61B8/08 , A61B8/485 , A61B34/25 , A61B2090/378 , G01S7/52036 , G01S7/52042 , G01S15/899 , G01S15/8993
摘要： Feedback of position is provided for high intensity focused ultrasound. The location of a beam from a HIFU transducer is determined using ultrasound imaging. The ultrasound imaging detects tissue displacement caused by a beam transmitted from the HIFU transducer. The displacement or information derived from the displacement may be used to determine a center line or point location (e.g., foci) of the tissues response to HIFU. The location of the line or point may be displayed in an image, such as an overlay or by color coding.
摘要翻译： 为高强度聚焦超声提供反馈位置。 使用超声成像确定来自HIFU传感器的光束的位置。 超声成像检测由HIFU换能器发射的束引起的组织位移。 从位移导出的位移或信息可以用于确定组织对HIFU的响应的中心线或点位置（例如，焦点）。 线或点的位置可以显示在图像中，例如叠加或通过颜色编码。
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47.发明申请公开(公告)号：US20090036749A1
公开(公告)日：2009-02-05
申请号：US11890124
申请日：2007-08-03
IPC分类号： A61B5/00
CPC分类号： G06T15/08 , A61B8/06 , A61B8/13 , A61B8/481 , A61B8/488 , G06F19/00 , G06T5/50 , G06T2207/10132
摘要： Separate renderings are performed for data of a same medical imaging mode. The data is processed differently prior to rendering and/or rendered differently to enhance desired image information. For example, a same set of ultrasound B-mode data is rendered with opacity rendering and with maximum intensity projection or surface rendering. The surface or maximum intensity projection highlights strong transitions associated with bones. The opacity rendering maintains tissue information. Different sets of B-mode data may be separately rendered, such as one set processed to emphasize contrast agent response and another set processed to emphasize tissue. The separate renderings are aligned and combined. The combined rendering is output as an image.
摘要翻译： 对于相同医学成像模式的数据执行单独的渲染。 数据在渲染之前被不同地处理和/或以不同的方式进行处理以增强期望的图像信息。 例如，使用不透明度渲染和最大强度投影或表面渲染渲染相同的一组超声B模式数据。 表面或最大强度投影突出显示与骨骼相关的强烈转变。 不透明度呈现维持组织信息。 可以单独呈现不同组的B模式数据，例如一组被处理以强调造影剂响应，另一组被处理以强调组织。 单独的渲染对齐并组合。 组合渲染作为图像输出。
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公开(公告)号：US07022073B2
公开(公告)日：2006-04-04
申请号：US10405136
申请日：2003-04-02
IPC分类号： A61B8/00
CPC分类号： G06K9/4609 , G06K2209/05 , G06T7/12 , G06T7/149 , G06T7/187 , G06T2207/10132 , G06T2207/20104 , G06T2207/20116 , G06T2207/30101
摘要： Methods and systems for detecting a border in a medical image are provided. A boundary is chosen as a connected curve whose tangent is substantially perpendicular to the gradient of the image everywhere along the curve. As an alternative to a tangent, a normal or other border direction may be used. At a given point within the image, the tangent to the boundary and the image gradient direction are orthogonal. Using an initial boundary detection, the boundary associated with the minimum cost or associated with the closest boundary where the boundary tangent and the image gradient directional are orthogonal for locations along the boundary is identified. By refining an initial border location to minimize divergence from the boundary tangent being orthogonal to the image gradient direction or by identifying a border based on the orthogonal relationship, accurate border detection may be provided in ultrasound images as well as other medical images.
摘要翻译： 提供了用于检测医学图像中的边界的方法和系统。 选择边界作为连接曲线，其切线基本上垂直于沿着曲线的各处的图像的梯度。 作为切线的替代，可以使用正常或其他边界方向。 在图像中的给定点处，边界的切线和图像梯度方向是正交的。 使用初始边界检测，识别与边界相关的边界，其边界切线和图像梯度方向对于沿着边界的位置是正交的，与最小成本相关联或与最接近的边界相关联。 通过优化初始边界位置以最小化与图像梯度方向正交的边界切线的偏离，或通过基于正交关系识别边界，可以在超声图像以及其它医学图像中提供准确的边界检测。
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公开(公告)号：US20050096543A1
公开(公告)日：2005-05-05
申请号：US10861268
申请日：2004-06-04
申请人： John Jackson , Liexiang Fan , Matthew Holladay , David Gustafson
发明人： John Jackson , Liexiang Fan , Matthew Holladay , David Gustafson
CPC分类号： G01S15/8981 , A61B6/503 , A61B6/504 , A61B8/0891 , A61B8/488 , A61B8/5276 , G01S7/52036 , G01S7/52066 , G01S7/52071 , G01S15/8988 , G06T7/248 , G06T2207/10132
摘要： Motion of a region of interest is tracked in medical imaging. For example, velocity information, such as colored Doppler velocity estimates independent of tracking from one image to another image, are used to indicate an amount of motion between the images. The velocity assisted tracking may be used for one dimensional tracking (e.g., for M-mode images), for tracking in two dimensional images, or for tracking between three dimensional representations. As an alternative or additional example, physiological signal information is used to assist in the tracking determination. A physiological signal may be used to model the likely movement of an organ being imaged to control or adjust matching search patterns and limits. The modeling may also be used to independently determine movement or for tracking. The independently determined tracking is then combined with tracking based on medical data or other techniques. The cost function or other metric for determining the sufficiency or a match may include information modeled from or selected as a function of the physiological cycle signal in addition to other matching calculations. The fusion of physiological signal information with image data tracking may improve the tracking.
摘要翻译： 感兴趣的区域的运动在医学成像中被跟踪。 例如，速度信息，例如独立于从一幅图像到另一幅图像的跟踪的彩色多普勒速度估计，用于指示图像之间的运动量。 速度辅助跟踪可以用于一维跟踪（例如，用于M模式图像），用于在二维图像中跟踪或用于三维表示之间的跟踪。 作为替代或附加示例，使用生理信号信息来辅助跟踪确定。 可以使用生理信号来对被成像的器官的可能运动进行建模，以控制或调整匹配的搜索模式和限制。 建模也可以用于独立地确定运动或跟踪。 然后将独立确定的跟踪与基于医疗数据或其他技术的跟踪组合。 用于确定足够或匹配的成本函数或其他度量可以包括除了其他匹配计算之外，根据生理周期信号建模或选择的信息。 生理信号信息与图像数据跟踪的融合可以改善跟踪。
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公开(公告)号：US06264609B1
公开(公告)日：2001-07-24
申请号：US09396153
申请日：1999-09-15
IPC分类号： A61B800
CPC分类号： A61B8/0858 , A61B5/02007
摘要： The present invention relates generally to a medical device, and more particularly to ultrasound apparatus and methods for the identification and characterization of tissues, tissue transitions and tissue constituent structures.
摘要翻译： 本发明一般涉及医疗装置，更具体地涉及用于识别和表征组织，组织转变和组织结构结构的超声装置和方法。
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