公开(公告)号：US20250144399A1

公开(公告)日：2025-05-08

申请号：US19013744

申请日：2025-01-08

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Jacob Leisner Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/122 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/205 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/804 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54

Abstract: Apparatus and methods are described including a left-ventricular assist device. A pump pumps blood from the subject's left ventricle to the subject's aorta, via a tube. A distal-tip element is disposed distally to the pump and defines a straight proximal portion that defines a longitudinal axis, and a curved distal portion that is shaped such as to curve in a first direction with respect to the longitudinal axis of the straight proximal portion before passing through an inflection point and curving in a second direction with respect to the longitudinal axis of the straight proximal portion, such that the curved distal portion defines a bulge on one side of the longitudinal axis of the straight proximal portion. Other applications are also described.

公开(公告)号：US20250144398A1

公开(公告)日：2025-05-08

申请号：US19013727

申请日：2025-01-08

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Jacob Leisner Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/122 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/205 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/804 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54

Abstract: Apparatus and methods are described including a left-ventricular assist device configured to assist left-ventricular functioning of a subject. The left-ventricular assist device includes a frame, a rigid axial shaft extending from a proximal end of the frame to a distal end of the frame, and an impeller disposed on the rigid axial shaft. A motor is disposed outside the subject's body, and a flexible drive cable extends from outside the subject's body to the axial shaft. The drive cable imparts rotational motion from the motor to the rigid axial shaft, to thereby rotate the impeller. Other applications are also described.

公开(公告)号：US20250090833A1

公开(公告)日：2025-03-20

申请号：US18958181

申请日：2024-11-25

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M60/422 ,  A61B5/0215 ,  A61B5/283 ,  A61M60/13 ,  A61M60/135 ,  A61M60/148 ,  A61M60/174 ,  A61M60/237 ,  A61M60/40 ,  A61M60/414 ,  A61M60/419 ,  A61M60/50 ,  A61M60/531 ,  A61M60/538 ,  A61M60/554 ,  A61M60/806 ,  A61M60/818 ,  A61M60/824 ,  A61M60/825 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

Abstract: Apparatus and methods are described including a blood pump configured to be placed inside a body of subject. The blood pump includes an impeller that defines a lumen therethrough, and an axial shaft that passes through the lumen. The impeller is configured to assume a radially-constrained configuration by becoming axially elongated. Other applications are also described.

公开(公告)号：US20250082920A1

公开(公告)日：2025-03-13

申请号：US18955121

申请日：2024-11-21

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Jacob Leisner Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/122 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/205 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/804 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54

Abstract: Apparatus and methods are described including a blood pump that includes an impeller configured to pump blood through a subject's body, and a frame disposed around the impeller. In a radially-non-constrained configuration of the frame, the frame defines a proximal conical portion and a cylindrical portion disposed distally to the proximal conical portion. The blood pump is configured such that such that, during at least some of the operation of the blood pump, at least a portion of the impeller is disposed within the proximal conical portion of the frame. Other applications are also described.

公开(公告)号：US12207906B2

公开(公告)日：2025-01-28

申请号：US17070670

申请日：2020-10-14

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

Abstract: Apparatus and methods are described including a ventricular assist device that includes a tube configured to traverse a subject's aortic valve. The tube defines a generally-cylindrical central portion, and a proximal conical portion that narrows from a proximal end of the central portion to a proximal end of the tube. The tube defines one or more blood inlet openings in a vicinity of a distal end of the tube, and one or more blood outlet openings that extend axially from the central portion of the tube at least partially into the proximal conical portion of the tube. A blood pump pumps blood into the tube from the subject's left ventricle through the one or more blood inlet openings, and from the tube into the aorta through the one or more blood outlet openings. Other applications are also described.

公开(公告)号：US20250000376A1

公开(公告)日：2025-01-02

申请号：US18882984

申请日：2024-09-12

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

Abstract: Apparatus and methods are described including a left ventricular assist device that includes an axial flow impeller configured to be disposed within a subject's left ventricle and to pump blood axially from the subject's left ventricle to the subject's aorta. A frame is disposed around the impeller, the frame being shaped such that, in a non-radially-constrained configuration of the frame, the frame defines a central cylindrical portion, and a distal conical portion. The frame is at least partially covered with one or more tube portions, the tube portions defining one or more blood-inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube portions, wherein at least some of the one or more blood-inlet openings are at least partially disposed over the distal conical portion of the frame. Other applications are also described.

公开(公告)号：US20240277996A1

公开(公告)日：2024-08-22

申请号：US18652956

申请日：2024-05-02

Applicant: Magenta Medical Ltd

Inventor： Yosi Tuval ,  Gad Lubinsky ,  Victor Troshin ,  Hagit Zemer Harel ,  Ori Friedland ,  Daniel Rosenblum ,  Avi Rozenfeld

IPC: A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

CPC classification number: A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

Abstract: Apparatus and methods are described including a ventricular assist device that includes an axial shaft and an impeller disposed on the axial shaft, the impeller being configured to pump blood. A frame is disposed around the impeller. A distal thrust bearing is disposed within the frame, the distal end of the axial shaft being configured to engage with the distal thrust bearing such as to prevent the axial shaft from undergoing axial motion in response to variations in the pressure gradient against which the impeller pumps blood. A plurality of connecting struts extend radially inwardly from the frame to the distal thrust bearing and couple the thrust bearing to the frame. The frame and the connecting struts are formed as a single integral body. Other applications are also described.

公开(公告)号：US20240277995A1

公开(公告)日：2024-08-22

申请号：US18652930

申请日：2024-05-02

Applicant: Magenta Medical Ltd

Inventor： Yosi Tuval ,  Gad Lubinsky ,  Victor Troshin ,  Hagit Zemer Harel ,  Ori Friedland ,  Daniel Rosenblum ,  Avi Rozenfeld

IPC: A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

CPC classification number: A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

Abstract: Apparatus and methods are described including packaging for a ventricular assist device. The packaging defines a pump-head chamber in which the pump head is packaged in a non-radially constrained configuration. A catheter-securement piece is shaped to define a hole and is configured to secure a distal end of the delivery catheter to the packaging by securing the delivery catheter within the hole. The packaging is configured such that the pump head is configured to be radially constrained by being retracted into the distal end of the delivery catheter, while the delivery catheter is secured within the hole. Other applications are also described.

公开(公告)号：US12023476B2

公开(公告)日：2024-07-02

申请号：US17173944

申请日：2021-02-11

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804

CPC classification number: A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

Abstract: Apparatus and methods are described including a blood pump configured to be placed inside a body of subject. The blood pump includes an impeller, a frame disposed around the impeller, and a distal-tip portion disposed distally with respect to the frame. A duckbill valve is disposed entirely within a distal most 10 mm of the distal-tip portion. The duckbill valve defines a wide inlet and a narrow tip that defines a slit therethrough. The duckbill valve is proximally facing, such that the wide inlet faces a distal end of the distal-tip portion and such that the narrow tip faces away from the distal end of distal-tip portion. Other applications are also described.

公开(公告)号：US11944800B2

公开(公告)日：2024-04-02

申请号：US17177296

申请日：2021-02-17

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804

CPC classification number: A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

Abstract: Apparatus and methods are described including a blood pump configured to be placed inside a body of subject, the blood pump including an impeller configured to pump the subject's blood by rotating, and an axial shaft upon which the impeller is disposed. Proximal and distal radial bearings are configured to stabilize the axial shaft radially during rotation of the impeller. An atraumatic distal-tip portion is disposed distally with respect to the impeller, the atraumatic distal-tip portion including an inflatable portion. A purging fluid is pumped toward the distal-tip portion, such as to (a) purge the distal bearing, and (b) inflate the inflatable portion of the distal-tip portion. Other applications are also described.