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公开(公告)号：US20170312751A1
公开(公告)日：2017-11-02
申请号：US15646578
申请日：2017-07-11
发明人： Eli N. Glezer , Stephen Higgins , Sandor Kovacs , Sudeep Kumar , Kenneth Page , Kristian Roth , George Sigal
CPC分类号： B01L7/525 , B01L3/5027 , B01L2200/027 , B01L2200/0605 , B01L2200/0621 , B01L2200/0631 , B01L2200/10 , B01L2200/146 , B01L2200/16 , B01L2300/0645 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/0883 , B01L2400/0487 , B01L2400/0688 , B01L2400/0694 , C12Q1/686
摘要： Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge.
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公开(公告)号：US20170160281A1
公开(公告)日：2017-06-08
申请号：US15440136
申请日：2017-02-23
发明人： Anahit Aghvanyan , Eli N. Glezer , John Kenten , Sudeep Kumar , Galina Nikolenko , Martin Stengelin
IPC分类号： G01N33/574
CPC分类号： G01N33/57423 , A61K39/39533
摘要： The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号：US20160349253A1
公开(公告)日：2016-12-01
申请号：US15206656
申请日：2016-07-11
发明人： Sudeep Kumar , George Sigal , Michael Tsionsky
IPC分类号： G01N33/543 , C12Q1/68
CPC分类号： G01N33/54386 , C12Q1/6823 , C12Q1/6832 , C12Q1/6834 , G01N33/5306 , G01N2446/00 , G01N2458/30
摘要： The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.
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公开(公告)号：US20220397579A1
公开(公告)日：2022-12-15
申请号：US17773896
申请日：2020-11-04
发明人： Sunsanee Kanjananimmanont , Sudeep Kumar , Navaratnam Manjula , Simone Barbero , Martin Stengelin , George Sigal
IPC分类号： G01N33/68 , G01N33/543
摘要： The invention relates to methods and kits for quantitating radiation exposure in a subject exposed to radiation, at risk of exposure to radiation or suspected of having been exposed to radiation. In embodiments, the present disclosure provides multiplexed immunoassays for quantifying amounts of biomarkers for assessing radiation exposure in a sample. Also provided herein are kits for performing the multiplexed assays.
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公开(公告)号：US20220390469A1
公开(公告)日：2022-12-08
申请号：US17890782
申请日：2022-08-18
发明人： Jeffrey Debad , Eli N. Glezer , Sudeep Kumar
IPC分类号： G01N33/68 , G01N33/574
摘要： The present invention relates to methods of diagnosing an inflammatory disorder in a patient, as well as methods of monitoring the progression of an inflammatory disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号：US11320366B2
公开(公告)日：2022-05-03
申请号：US16219030
申请日：2018-12-13
发明人： Nicholas Anderson , Jeffery Debad , Eli N. Glezer , Sudeep Kumar , Noel Lawrence , Kenneth Page , George Sigal , Sharon West
IPC分类号： B01L9/00 , G01N21/05 , G01N21/69 , G01N21/76 , B01L3/00 , G01N21/03 , G01F23/02 , G01F23/292 , G01N1/10 , B01L7/00
摘要： Assay cartridges are described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain embodiments, these cartridges are adapted to receive and analyze a sample collected on an applicator stick. Also described are kits including such cartridges and a cartridge reader configured to analyze an assay conducted using an assay cartridge.
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公开(公告)号：US20210060567A1
公开(公告)日：2021-03-04
申请号：US17032524
申请日：2020-09-25
发明人： Eli N. Glezer , Stephen Higgins , Sandor Kovacs , Sudeep Kumar , Kenneth Page , Kristian Roth , George Sigal
摘要： Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge.
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公开(公告)号：US20200158731A1
公开(公告)日：2020-05-21
申请号：US16748026
申请日：2020-01-21
发明人： Anahit Aghvanyan , Eli N. Glezer , John Kenten , Sudeep Kumar , Galina Nikolenko , Martin Stengelin
IPC分类号： G01N33/574 , A61K39/395
摘要： The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号：US20200035333A1
公开(公告)日：2020-01-30
申请号：US16594301
申请日：2019-10-07
发明人： Charles M. Clinton , Xinri Cong , Eli N. Glezer , Sudeep Kumar , Carl Stevens , Michael Vock , Jon S. Willoughby
IPC分类号： G16C20/20 , G01N35/00 , G01N33/543 , B01L3/00 , G16H10/40
摘要： The present invention relates to methods, devices and systems for associating assay information with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system includes a reader adapted to read/erase/write information from/to an assay consumable identifier associated with the assay consumable. Various types of assay information are described, as well as methods of using such information in the conduct of an assay by an assay system.
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公开(公告)号：US10446263B2
公开(公告)日：2019-10-15
申请号：US14862298
申请日：2015-09-23
发明人： Charles M. Clinton , Xinri Cong , Eli N. Glezer , Sudeep Kumar , Carl Stevens , Michael Vock , Jon S. Willoughby
摘要： The present invention relates to methods, devices and systems for associating assay information with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system includes a reader adapted to read/erase/write information from/to an assay consumable identifier associated with the assay consumable. Various types of assay information are described, as well as methods of using such information in the conduct of an assay by an assay system.
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