摘要:
Disclosed is a compound represented by General formula (I), a pharmaceutically acceptable salt thereof, or a solvate of the compound or the pharmaceutically acceptable salt, which has an inhibitory activity of the production of Aβ or a BACE1-inhibiting activity, and is therefore useful as a prophylactic or therapeutic agent for Aβ-induced neurodegenerative diseases typified by Alzheimer-type dementia. Wherein the ring A represents a C6-14 aryl group or the like; L represents —NReCO— [wherein Re represents a hydrogen atom or the like] or the like; the ring B represents a C6-14 aryl group or the like; X represents a C1-3 alkylene group or the like; Y represents a single bond or the like; Z represents a C1-3 alkylene group or the like; R1 and R2 independently represent a hydrogen atom or the like; and R3, R4, R5 and R6 independently represent a hydrogen atom, a halogen atom or the like.
摘要:
In a gas concentration measuring apparatus, a measurement substrate is provided. A conductive pattern portion is formed in the measurement substrate. The conductive pattern portion includes a signal input pattern constituting the signal processing circuit and electrically connected to the connection terminal, said signal input pattern having direct current impedance with respect to the connection terminal, said direct current impedance being 10 percent or less of the input impedance of the connection terminal; a different potential pattern having a potential difference of 2 V or over from a potential of the signal input pattern; and a guard pattern having a substantially constant potential and a potential difference of less than 0.5 V from the potential of the signal input pattern, said guard pattern being arranged on at least a portion of the measurement substrate, said at least portion of the measurement substrate being located between the signal input pattern and the different potential pattern.
摘要:
A tractor of the present invention can reduce a manufacturing cost of a lift arm support body. The tractor is configured such that a lift arm is mounted on an upper portion of a transmission casing by way of a lift arm support body, the lift arm is hydraulically controllable by a hydraulic control valve by way of a hydraulic circuit body, and the hydraulic circuit body and the hydraulic control valve are fixed to the transmission casing as bodies separate from a lift arm support body.
摘要:
The present invention aims at allowing a tractor to easily set the creep transmission specification and the non-creep transmission specification. According to the present invention, in a tractor in which a transmission part is interlockingly connected with a prime mover part, and power is transmitted to a front wheel and a rear wheel from the transmission part thus enabling the traveling of the tractor, a creep transmission part is detachably interlockingly connected with the transmission part. By detachably mounting the creep transmission part to the transmission part in this manner, it is possible to easily set the creep transmission specification and the non-creep transmission specification.
摘要:
This invention constructs within the LAN a private area network (PAN) which is configured by terminal devices (personal computers and the like) of a specific group, is hardly influenced by the LAN traffic, and has high security. For this purpose, a PAN server which manages the communication route between specific terminals is installed within the LAN. The PAN server sets the communication route of each terminal device as label information, and causes switches and terminals to set pieces of label information generated for them. When the frame of data from a given port of each connection switch contains information representing PAN communication, the connection switch outputs the data to only a port specified by routing label information described in the frame.
摘要:
Condensed pyridine compounds represented by formula (I): wherein: R1 and R3 are, independently, hydrogen, halogen, lower alkyl, or lower alkoxy; R2 represents an amino substituent; ring A is a benzene ring, pyridine ring, thiophene ring, or furan ring; and B represents a substituent containing a ring structure. Also, pharmaceutically acceptable salt and hydrates thereof. These compounds are clinically useful medicaments having; serotonin antagonism, and in particular, for treating, ameliorating, or preventing spastic paralysis. They are also useful as central muscle relaxants for ameliorating myotonia.
摘要:
A chuck unit for a machine tool is capable of holding a workpiece installed on a spindle by workpiece holding members that move in a radial direction with respect to an axial center. Workpiece holding rods are provided at the workpiece holding member and move radially. Screw operating portions are operated by a rotating operation jig at an outer peripheral side of the chuck unit. A workpiece end face abutment moves and holds the workpiece in the axial direction.
摘要:
A discharge lamp control circuit for a vehicular lamp uses a starting circuit capacitor that is charged by the same high voltage generator used later as the lamp's power source after it is turned on. As a result, no separate dedicted starting transformer is necessary. Further, a thyristor and diode are used in the starting circuit in place of a spark-gap for initially activating the discharge lamp.
摘要:
In a discharge lamp control circuit for a discharge lamp mounted on a vehicle, a capacitor in a starting circuit is charged by a high voltage generated by a transformer used in a direct current power source circuit. A transformer necessary for the starting circuit and the transformer necessary for the direct current power source circuit can commonly be used for cost reduction. Further, a thyristor is used in the starting circuit in place of a gap for activating the discharge lamp.
摘要:
A skin activator containing as an effective component a compound represented by the following general formula (I), and external skin preparations containing it. It has an excellent glycosaminoglycan production-accelerating effect. ##STR1##