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    BIOFILM-INHIBITING MEDICAL PRODUCTS
    45.
    发明申请
    BIOFILM-INHIBITING MEDICAL PRODUCTS 有权
    生物膜抑制医疗产品

    公开(公告)号：US20080181950A1

    公开(公告)日：2008-07-31

    申请号：US12019477

    申请日：2008-01-24

    申请人： Brian L. Bates ,  Michael C. Hiles ,  Chad E. Johnson

    发明人： Brian L. Bates ,  Michael C. Hiles ,  Chad E. Johnson

    IPC分类号： A01N25/00 ,  A01N31/00 ,  A61P17/02

    CPC分类号： A61L15/40 ,  A61L15/44 ,  A61L2300/102 ,  A61L2300/404

    摘要： A biofilm-inhibiting medical product includes a carrier formed from a natural, bioremodelable material, whereby the carrier includes a biocidal bismuth thiol agent and/or one or more other biofilm-inhibiting or wound healing agents. A method for using the biofilm-inhibiting medical product to treat a wound or tissue defect in a patient's body is described.

    摘要翻译： 生物膜抑制医疗产品包括由天然的生物可重塑材料形成的载体，由此所述载体包含杀生物铋硫醇试剂和/或一种或多种其它生物膜抑制或伤口愈合剂。 描述了使用生物膜抑制医疗产品来治疗患者体内的伤口或组织缺陷的方法。

    Medical radiation treatment delivery apparatus
    48.
    发明授权
    Medical radiation treatment delivery apparatus 失效
    医疗放射治疗仪器

    公开(公告)号：US6159141A

    公开(公告)日：2000-12-12

    申请号：US150814

    申请日：1998-09-11

    申请人： Marc G. Apple ,  Brian L. Bates ,  John A. DeFord ,  Neal E. Fearnot

    发明人： Marc G. Apple ,  Brian L. Bates ,  John A. DeFord ,  Neal E. Fearnot

    IPC分类号： A61B1/00 ,  A61F2/958 ,  A61M36/04 ,  A61N5/10 ,  A61N5/00

    CPC分类号： A61M25/1011 ,  A61N5/1002 ,  A61N5/1048 ,  A61M2025/1047 ,  A61M2025/1072

    摘要： A catheter apparatus (20) and radiation dosimetry unit indicator (21) for delivery of a prescribed radiation dose to a patient. The catheter is filled with a radiation carrier material such as an inert radioactive gas (12) for the treatment of, for example, restenosis after angioplasty, and malignancies. The inflated catheter includes a plurality of discrete chambers such as balloon sections (22, 24, 26) for transporting the radioactive carrier material, and a plurality of discrete chambers (32, 34, 36) enabling substantial blood flow through the artery during treatment with the prescribed radiation. The inflated catheter can also comprise a one-unit balloon. A specific metal coating enhances the radiation dose delivered to the target. The wall (25) of the inflation lumen attenuates transmission dose to the blood circulating through the hollow inner lumen of the catheter device. The system also creates increased by-product radiation, from the impact of beta particles and gamma protons traveling toward the lumen wall. A radiation dosimetry unit indicator (21) is positioned, disposed, or affixed to a calibrated catheter to assist the physician in prescribing radiation activity and exposure times.

    摘要翻译： 导管装置（20）和辐射剂量测定单元指示器（21），用于向患者输送规定的辐射剂量。 导管填充有辐射载体材料，例如惰性放射性气体（12），用于治疗例如血管成形术后的再狭窄和恶性肿瘤。 膨胀的导管包括多个分立的腔室，例如用于运送放射性载体材料的气囊部分（22,24,26）和多个离散的腔室（32,34,36），其能够在治疗过程中使大量血液流过动脉， 规定的辐射。 充气导管还可以包括一个单一的气囊。 特定的金属涂层增强了传递给靶的辐射剂量。 充气腔的壁（25）衰减通过导管装置的中空内腔循环的血液的透射剂量。 该系统还产生增加的副产物辐射，从β粒子和γ质子向腔壁行进的影响。 辐射剂量测量单元指示器（21）被定位，设置或固定到校准的导管上，以帮助医师规定辐射活动和暴露时间。

    Apparatus and method for effecting percutaneous catheterization of a blood vessel using a small gauge introducer needle
    49.
    发明授权
    Apparatus and method for effecting percutaneous catheterization of a blood vessel using a small gauge introducer needle 失效
    使用小规格引导器针进行血管的经皮导管插入的装置和方法

    公开(公告)号：US4650472A

    公开(公告)日：1987-03-17

    申请号：US771025

    申请日：1985-08-30

    申请人： Brian L. Bates

    发明人： Brian L. Bates

    IPC分类号： A61M5/00

    CPC分类号： A61M25/09 ,  A61M2025/09175

    摘要： A apparatus and method for percutaneous catheterization of a blood vessel permitting use of a small gauge needle is shown. A 22 gauge needle is used for making the initial entry into the blood vessel. A wire guide is then introduced into the blood vessel through the introducer needle, the needle then being withdrawn. A catheter and an inner cannula are passed in unison over the wire guide, through the skin and into the blood vessel. The cannula is provided with a tapered tip which extends through the distal opening of the catheter, thereby providing a diametrical transition between the small wire guide and the relatively larger catheter, resulting in a minimum of trauma during insertion. Once the catheter is in place, the inner cannula and wire guide are withdrawn, leaving the catheter in place with a relatively large distal opening, thereby promoting good fluid flow characteristics of the catheter.

    摘要翻译： 示出了允许使用小规格针的血管的经皮导管插入装置和方法。 22号针头用于初始进入血管。 然后通过导引针将导线引导到血管中，然后将针抽出。 导管和内套管一起通过导线器通过皮肤并进入血管。 插管设置有锥形尖端，其延伸穿过导管的远端开口，从而在小导线器和相对较大的导管之间提供径向过渡，导致在插入期间最小的创伤。 一旦导管就位，内套管和导线导管就被取出，导管就位于相对较大的远端开口处，从而促进导管的良好流体流动特性。