公开(公告)号：US06659934B1

公开(公告)日：2003-12-09

申请号：US09469510

申请日：1999-12-22

申请人： James D. Hughett ,  Robert Michael Webster ,  Douglas Layland Armstrong ,  Byron Lee Boylston ,  Gregg T. Juett ,  Richard A. Hillstead ,  Jack C. Griffis, III ,  Andrew L. Lerohl ,  Mark Dehdashtian ,  Marvin A. Guiles

发明人： James D. Hughett ,  Robert Michael Webster ,  Douglas Layland Armstrong ,  Byron Lee Boylston ,  Gregg T. Juett ,  Richard A. Hillstead ,  Jack C. Griffis, III ,  Andrew L. Lerohl ,  Mark Dehdashtian ,  Marvin A. Guiles

IPC分类号： A61N500

CPC分类号： A61N5/1007 ,  A61N2005/1008

摘要： A transfer device usable in a system for intraluminal treatment of a selected site in a body of a patient in which the transfer device comprises an integral pump for pressurizing and circulating fluid through a fluid path defined by the transfer device and associated catheter. A removable fluid cartridge is provided including a reservoir from which fluid is drawn by the pump and into which fluid is returned after being circulated through the fluid path. The pump may be a peristaltic pump and the fluid cartridge may include an elongated fluid pick-up having an inlet through which fluid is introduced into the transfer device. The fluid pick-up is sized in length so that the inlet is always submerged in the fluid regardless of the orientation of the transfer device.

摘要翻译： 一种可用于管腔内治疗患者体内的选定部位的系统中的转移装置，其中所述转运装置包括用于通过由所述输送装置和相关导管限定的流体路径加压和循环流体的整体泵。 提供了可拆卸的流体盒，其包括储存器，流体由泵从该容器中被抽出，并且在通过流体路径循环之后流体返回到储存器中。 泵可以是蠕动泵，并且流体盒可以包括具有入口的细长流体拾取器，流体通过入口引入到输送装置中。 流体拾取器的长度尺寸使得入口总是浸没在流体中，而与传送装置的取向无关。

公开(公告)号：US06306074B1

公开(公告)日：2001-10-23

申请号：US09304783

申请日：1999-05-04

申请人： Ron Waksman ,  Thomas D. Weldon ,  Raphael F. Meloul ,  Richard A. Hillstead ,  Jonathan J. Rosen ,  George K. Bonnoitt, Jr. ,  David S. Halpern ,  Charles E. Larsen ,  Ian R. Crocker

发明人： Ron Waksman ,  Thomas D. Weldon ,  Raphael F. Meloul ,  Richard A. Hillstead ,  Jonathan J. Rosen ,  George K. Bonnoitt, Jr. ,  David S. Halpern ,  Charles E. Larsen ,  Ian R. Crocker

IPC分类号： A61M2902

CPC分类号： A61M37/0069 ,  A61M25/0029 ,  A61M25/1002 ,  A61M25/1006 ,  A61M2025/0037 ,  A61M2025/0039 ,  A61M2025/004 ,  A61N5/1002 ,  A61N5/1007 ,  A61N2005/1003 ,  A61N2005/1005 ,  A61N2005/1008 ,  A61N2005/1023

摘要： Apparatus and method are described for delivery of a treating element, such as a radiation source, through a catheter to a desired site in the intraluminal passageways of a patient, such as a coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty. The apparatus includes an elongated flexible catheter tube having proximal and distal end portions, with a lumen extending therebetween, and a diameter sufficiently small for insertion in to a patient's intraluminal passageways. One or more treating elements, such as a capsule or pellet containing radioactive material, is positionable within the lumen and movable between the proximal and distal end portions under the force of liquid flowing through the lumen. A method for using such apparatus, including a method for using such apparatus simultaneously with a balloon angioplasty procedure, is disclosed.

摘要翻译： 描述了用于将治疗元件（例如辐射源）通过导管递送到患者（例如冠状动脉）的管腔内通道中用于抑制形成瘢痕组织的可能发生的装置和方法 在球囊血管成形术后再狭窄。 该装置包括细长的柔性导管，其具有近端部分和远端部分，其间具有内腔，并且其直径足够小以插入病人的管腔内通道。 一个或多个处理元件，例如包含放射性物质的胶囊或丸粒，可定位在内腔内并且在液体流过内腔的力的作用下在近端部分和远端部分之间移动。 公开了一种使用这种装置的方法，包括与球囊血管成形术程序同时使用这种装置的方法。

公开(公告)号：US5509908A

公开(公告)日：1996-04-23

申请号：US230614

申请日：1994-04-21

申请人： Richard A. Hillstead ,  Joseph B. Muhlestein

发明人： Richard A. Hillstead ,  Joseph B. Muhlestein

IPC分类号： A61M25/00 ,  A61M25/06 ,  A61M5/00

CPC分类号： A61M25/0662 ,  A61M25/0097

摘要： A sheath introducer for a catheterization or similar procedure comprises a body having a upper portion and a lower portion, the lower portion being angled with respect to the upper portion; a curved tapering channel extending through the upper and lower portions; a cannula with a tapered distal end extending at an angle with respect to the upper portion a hemostatic valve having an access port and a fluid tight slit opening and seated within the upper portion and maintained by a cap; and an angled sideport in fluid communication with the channel. Optionally, a wiper flange extends inward within the valve access port which provide an additional fluid tight seal when a catheter is slidingly inserted, removed or maintained within the valve. A dilator can be adapted for use with the introducer by having a bend in the tube portion of the dilator.

摘要翻译： 用于导管插入或类似程序的护套引导器包括具有上部和下部的主体，下部相对于上部成一定角度; 延伸穿过上部和下部的弯曲的锥形通道; 具有锥形远端的套管，所述套管具有相对于所述上部一定角度延伸的止血阀，所述止血阀具有进入口和流体密封狭缝开口，并位于所述上部内并由盖保持; 以及与通道流体连通的倾斜侧台。 可选地，擦拭器凸缘在阀进入端口内向内延伸，当导管滑动地插入，移除或保持在阀内时，提供另外的流体密封。 扩张器可以通过在扩张器的管部分中具有弯曲而适于与导引器一起使用。

公开(公告)号：US5366472A

公开(公告)日：1994-11-22

申请号：US769005

申请日：1991-09-30

申请人： Richard A. Hillstead

发明人： Richard A. Hillstead

IPC分类号： A61F2/90 ,  A61M29/02 ,  A61M29/00

CPC分类号： A61M25/104 ,  A61F2/90 ,  A61F2/958 ,  A61M2025/1081 ,  A61M29/02

摘要： The dilatation balloon catheter assembly is adapted to be inserted into a blood vessel and comprises a single catheter body having a distal end, a distal end portion, and a proximal end, and a double wall dilatation balloon assembly including an inner inflatable balloon wall and an outer balloon wall with a space therebetween, the balloon walls each having a distal end and a proximal end, and each balloon wall surrounding and being connected at both its distal and proximal ends directly or indirectly to the distal end portion of the single catheter body.

摘要翻译： 扩张球囊导管组件适于插入血管并且包括具有远端，远端部分和近端的单个导管主体，以及双壁膨胀气囊组件，其包括内部可充气球囊壁和 外球囊壁之间具有空间，球囊壁各自具有远端和近端，并且每个球囊壁围绕并且在其远端和近端处直接或间接地连接到单个导管体的远端部分。

公开(公告)号：US5098440A

公开(公告)日：1992-03-24

申请号：US567199

申请日：1990-08-14

申请人： Richard A. Hillstead

发明人： Richard A. Hillstead

IPC分类号： A61B17/22 ,  A61B17/28 ,  A61B17/30 ,  A61B19/00 ,  A61F2/06 ,  A61F2/84

CPC分类号： A61B17/221 ,  A61B17/29 ,  A61F2/95 ,  A61B17/30 ,  A61B2017/2212 ,  A61B2017/2215 ,  A61B2090/3614 ,  A61B2090/3933 ,  A61F2002/9528

摘要： Method and apparatus for retrieving an object such as a stent from a subject. A catheter supports two wire loops that can be manipulated from outside the subject to engage the object. By manipulating the catheter and the wire loops, the object can be captured and drawn inside a guide catheter through which the catheter is inserted. The catheter and attached stent can then be pulled from the subject.

摘要翻译： 从对象中检索诸如支架的物体的方法和装置。 导管支撑两个线圈，可以从受试者的外部操纵以接合物体。 通过操纵导管和线环，物体可以被捕获并且被吸引到引导导管内，导管通过导管插入。 然后可以从受试者中拉出导管和附着的支架。

公开(公告)号：US5037392A

公开(公告)日：1991-08-06

申请号：US362253

申请日：1989-06-06

申请人： Richard A. Hillstead

发明人： Richard A. Hillstead

IPC分类号： A61F2/06 ,  A61F2/84 ,  A61M25/10

CPC分类号： A61M25/1027 ,  A61F2/958 ,  A61M25/1002 ,  A61M25/1038 ,  A61M2025/1004

摘要： The dilatation balloon assmebly comprises a catheter having a proximal end, a distal end and a distal end portion, the distal end portion having openings in the side wall thereof, and a dilatation balloon connected to and extending from the distal end of the catheter around and about the distal end portion of the catheter to a proximal end of the balloon which is also connected to the catheter. The balloon has at least three axially extending longitudinal creases therein whereby, when the balloon is in a deflated state, the maximum lateral extent in cross-section of the balloon is less than the diameter or lateral extent of a fully inflated balloon or a partially inflated balloon.

摘要翻译： 膨胀球囊组成包括具有近端，远端和远端部分的导管，其远端部分在其侧壁中具有开口，以及扩张球囊，其连接到导管的远端周围并且从导管的远端延伸， 围绕导管的远端部分到球囊的近端，其也连接到导管。 气球在其中具有至少三个轴向延伸的纵向折痕，由此当气囊处于放气状态时，球囊的横截面中的最大横向程度小于完全充气球囊的直径或横向程度或部分膨胀 气球。

公开(公告)号：US5019085A

公开(公告)日：1991-05-28

申请号：US484693

申请日：1990-02-23

申请人： Richard A. Hillstead

发明人： Richard A. Hillstead

IPC分类号： A61F2/06 ,  A61F2/84 ,  A61F2/88

CPC分类号： A61F2/88 ,  A61F2/95 ,  A61F2002/9511

摘要： A stent delivery system and method. A stent is routed to a desired position within a vessel within a subject. A delivery wire is routed out an opening in a delivery catheter and looped over a portion of the stent and then routed back inside the delivery catheter. At an extreme distal end of the stent, the wire again exits the delivery catheter, reengages the stent and is pushed back into the catheter center passageway. This compresses the stent into a form whereby the delivery catheter can be maneuvered through a vessel to position the stent. To release the stent from the delivery catheter, the delivery wire is retracted so that its distal end passes out both pair of openings in the delivery catheter allowing the stent to expand into engagement with the vessel wall.

摘要翻译： 一种支架输送系统及方法。 支架被路由到受试者内的血管内的期望位置。 输送线从输送导管中的开口排出并且环绕在支架的一部分上，然后在输送导管内返回。 在支架的最远端，线再次离开输送导管，重新接合支架并被推回到导管中心通道中。 这将支架压缩成一种形式，由此输送导管可以通过容器操纵以定位支架。 为了从输送导管释放支架，输送线缩回，使得其远端排出输送导管中的两对开口，允许支架膨胀成与血管壁接合。

公开(公告)号：US4921484A

公开(公告)日：1990-05-01

申请号：US223870

申请日：1988-07-25

申请人： Richard A. Hillstead

发明人： Richard A. Hillstead

IPC分类号： A61B17/03 ,  A61B17/22 ,  A61F2/958

CPC分类号： A61M25/10 ,  A61B17/320725

摘要： The mesh balloon catheter device includes a catheter having a distal end and a proximal end, a tube of woven interlaced filaments forming a tubular mesh and having a proximal end connected to the distal end of the catheter and a distal end, a flush tube or fiber optic tube extending through the catheter and the tubular mesh and fixed to the distal end of the tubular mesh, and a mechanism for moving the distal end of the tubular mesh toward the proximal end of the tubular mesh to cause the tubular mesh to balloon laterally outwardly to the shape of a mesh balloon.The moving mechanism can be realized by the flush tube or fiber optic tube connected to the distal end of the tubular mesh or by a control wire connected to the distal end of the tubular mesh and extending through the catheter.

摘要翻译： 网状气囊导管装置包括具有远端和近端的导管，形成管状网状物的编织隔行细丝管，并且具有连接到导管远端的近端和远端，冲洗管或纤维 延伸穿过导管和管状网并且固定到管状网的远端的光学管，以及用于将管状网的远端朝向管状网的近端移动以使管状网横向向外气球的机构 到网状气球的形状。 移动机构可以通过连接到管状网的远端的连接管或光纤管，或通过连接到管状网的远端并延伸通过导管的控制线实现。

公开(公告)号：US08365721B2

公开(公告)日：2013-02-05

申请号：US12870459

申请日：2010-08-27

申请人： Charles E. Larsen ,  Richard A. Hillstead ,  Roelof Trip ,  Eugene deJuan ,  Mark S. Humayun ,  Eberhard Fritz ,  Rainer Pintaske ,  Sabine Willenkamp ,  Gerd T. Phillipps

发明人： Charles E. Larsen ,  Richard A. Hillstead ,  Roelof Trip ,  Eugene deJuan ,  Mark S. Humayun ,  Eberhard Fritz ,  Rainer Pintaske ,  Sabine Willenkamp ,  Gerd T. Phillipps

IPC分类号： A61N5/00

CPC分类号： A61N5/1017

摘要： A method for performing intraocular brachytherapy and an apparatus for performing the same is disclosed. The apparatus preferably comprises a hand-held delivery device that advances a radiation source into an associated cannula or probe that is positioned adjacent the target tissue. The handpiece provides for shielded storage of the radiation source when retracted from the cannula and includes a slider mechanism for advancing and retracting the radiation source. The radiation source is mounted to a wire that has a flexible distal end and a relatively stiffer proximal end. A positioning system for the cannula is also disclosed.

摘要翻译： 公开了一种用于进行眼内近距离放射治疗的方法及其执行装置。 该装置优选地包括将辐射源前进到与靶组织相邻定位的相关套管或探针中的手持递送装置。 所述手持件在从套管缩回时提供辐射源的屏蔽存储，并且包括用于前进和后退辐射源的滑块机构。 辐射源安装到具有柔性远端和较硬的近端的导线上。 还公开了用于套管的定位系统。

公开(公告)号：US07803102B2

公开(公告)日：2010-09-28

申请号：US11593683

申请日：2006-11-07

申请人： Charles E. Larsen ,  Richard A. Hillstead ,  Roelof Trip ,  Eugene deJuan ,  Mark S. Humayun ,  Eberhard Fritz ,  Rainer Pintaske ,  Sabine Willenkamp ,  Gerd T. Phillipps

发明人： Charles E. Larsen ,  Richard A. Hillstead ,  Roelof Trip ,  Eugene deJuan ,  Mark S. Humayun ,  Eberhard Fritz ,  Rainer Pintaske ,  Sabine Willenkamp ,  Gerd T. Phillipps

IPC分类号： A61N5/00

CPC分类号： A61N5/1017

摘要： A method for performing intraocular brachytherapy and an apparatus for performing the same is disclosed. The apparatus preferably comprises a hand-held delivery device that advances a radiation source into an associated cannula or probe that is positioned adjacent the target tissue. The handpiece provides for shielded storage of the radiation source when retracted from the cannula and includes a slider mechanism for advancing and retracting the radiation source. The radiation source is mounted to a wire that has a flexible distal end and a relatively stiffer proximal end. A positioning system for the cannula is also disclosed.

摘要翻译： 公开了一种用于进行眼内近距离放射治疗的方法及其执行装置。 该装置优选地包括将辐射源前进到与靶组织相邻定位的相关套管或探针中的手持递送装置。 所述手持件在从套管缩回时提供辐射源的屏蔽存储，并且包括用于前进和后退辐射源的滑块机构。 辐射源安装到具有柔性远端和较硬的近端的导线上。 还公开了用于套管的定位系统。