公开(公告)号：US20080248562A1

公开(公告)日：2008-10-09

申请号：US10586730

申请日：2005-01-20

申请人： Tadashi Sano ,  Ryo Miyake ,  Yasuhiko Sasaki ,  Tatsuo Sumino ,  Kazuichi Isaka ,  Hajime Ikuta

发明人： Tadashi Sano ,  Ryo Miyake ,  Yasuhiko Sasaki ,  Tatsuo Sumino ,  Kazuichi Isaka ,  Hajime Ikuta

IPC分类号： C12M1/00

CPC分类号： G01N15/10 ,  G01N2015/0088

摘要： A microorganism separation device includes: sample solution supply means (30) for supplying a sample solution (40) stored within a sample solution reservoir (32) to a first flow path (12); a microorganism sensor (22) that is capable of detecting a monadelphous microorganism in the sample solution (40) that passes through the first flow path (12); a controller (24) that stops to supply the sample solution (40) to the first flow path (12) and discharges the detected microorganism together with the sample solution (40) from a termination side of the first flow path (12) on the basis of a detection result of the microorganism by the microorganism sensor (22); and an acceptor (52) that receives a droplet (28) of the sample solution (40) that is discharged from the termination side of the first flow path (12).

摘要翻译： 微生物分离装置包括：样品溶液供给装置（30），用于将存储在样品溶液储存器（32）内的样品溶液（40）供应到第一流动路径（12）; 微生物传感器（22），其能够检测通过所述第一流路（12）的所述样品溶液（40）中的单位微生物; 控制器（24），停止向第一流路（12）供应样品溶液（40），并将检测到的微生物与样品溶液（40）一起从第一流路（12）的终止侧排出到 微生物传感器（22）对微生物的检测结果的基础; 以及接收从第一流路（12）的终端侧排出的样品溶液（40）的液滴（28）的受体（52）。

公开(公告)号：US20070238162A1

公开(公告)日：2007-10-11

申请号：US11214948

申请日：2005-08-31

申请人： Tetsuro Miyamoto ,  Hiroyuki Takei ,  Shigenori Togashi ,  Ryo Miyake

发明人： Tetsuro Miyamoto ,  Hiroyuki Takei ,  Shigenori Togashi ,  Ryo Miyake

IPC分类号： C12M3/00

CPC分类号： G01N21/253 ,  G01N21/553 ,  G01N35/028 ,  G01N35/1095

摘要： In a measuring apparatus for biomolecule interaction, a fine particle sensor surface is dipped in a buffer solution in a reaction vessel to conduct spectral measurement by way of optical fibers. The buffer solution in the reaction vessel is made to enter an upper reaction vessel and discharged from a flow channel. Air is injected from a flow channel to inject a specimen from the discharge port to the reaction vessel. Then the specimen is sucked into the reaction vessel and brought into contact with the sensor surface where a ligand and an analyte in the specimen are bonded. Bonding is measured by a spectrophotometer through the optical fibers. A buffer solution is injected from the injection flow channel into the reaction vessel and the specimen is discharged out of the flow channel. The dissociation process in which the biomolecules are dissociated along with lowering of the concentration is measured.

摘要翻译： 在用于生物分子相互作用的测量装置中，将细颗粒传感器表面浸入反应容器中的缓冲溶液中以通过光纤进行光谱测量。 将反应容器中的缓冲溶液进入上反应容器并从流动通道排出。 空气从流动通道注入，将样品从排放口注入反应容器。 然后将样品吸入反应容器中，并与样品中的配体和分析物结合的传感器表面接触。 通过分光光度计通过光纤测量粘合。 将缓冲溶液从注射流通道注入反应容器中，并将样品从流动通道排出。 测量其中生物分子随浓度降低而解离的解离过程。

公开(公告)号：US20050192759A1

公开(公告)日：2005-09-01

申请号：US10986804

申请日：2004-11-15

申请人： Ryo Miyake ,  Toshio Otaguro ,  Ryoji Okada ,  Naoya Sasaki

发明人： Ryo Miyake ,  Toshio Otaguro ,  Ryoji Okada ,  Naoya Sasaki

IPC分类号： G01N37/00 ,  B01L3/00 ,  G06F17/50 ,  G06F17/60 ,  G06F19/00 ,  G01N33/48

CPC分类号： G06F17/50 ,  B01L3/5027 ,  G06Q50/24

摘要： A computer program embodied on a computer readable medium for designing a treating member contains a first code segment adapted to acquiring a piece of input information containing a treatment sequence; and a second code segment adapted to designing a flow path along which a sample moves, based on the piece of input information.

摘要翻译： 包含在用于设计治疗部件的计算机可读介质上的计算机程序包含适于获取包含处理序列的输入信息的第一代码段; 以及第二代码段，其适于基于所述输入信息来设计样本移动所沿着的流动路径。

公开(公告)号：US20050048540A1

公开(公告)日：2005-03-03

申请号：US10870064

申请日：2004-06-18

申请人： Hisao Inami ,  Yasuhiko Sasaki ,  Ryo Miyake

发明人： Hisao Inami ,  Yasuhiko Sasaki ,  Ryo Miyake

IPC分类号： G01N33/50 ,  B01L3/00 ,  B01L7/00 ,  B01L9/00 ,  C12M1/00 ,  C12M1/34 ,  C12N15/09 ,  C12Q1/68 ,  G01N37/00

CPC分类号： B01L9/527 ,  B01L3/5027 ,  B01L3/52 ,  B01L7/52 ,  B01L2200/025 ,  B01L2200/027 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2400/0487

摘要： The present invention provides an analytical chip that is easy to handle, inexpensive, and for which the extraction of gene from a sample and analysis thereof can be automated to one process, and a small-sized and portable analytical apparatus equipped therewith. The chip for processing of gene that is equipped with an injection port into which a sample containing gene is delivered, a gene extraction part into which a solution containing said sample is introduced and which has a gene-binding carrier that binds to said gene, a washing solution-storing part that stores the washing solution to be introduced into said gene extraction part, and a reaction part into which said gene captured in said extraction part is introduced, wherein a fluid channel through which said washing solution is introduced from said washing solution-storing part has been connected to a region more remote from said injection port than from a region into which a solution containing said sample is introduced in said gene extraction part is obtained.

摘要翻译： 本发明提供一种易于处理，价格便宜的分析芯片，并且可以将样品中的基因提取及其分析自动化为一个过程，以及配备有该样品的小型便携式分析装置。 用于加工含有含有基因的样品的注入口的基因的加工用芯片，导入了含有所述样品的溶液的基因提取部，其具有与所述基因结合的基因结合载体， 将要引入所述基因提取部分的洗涤溶液的洗涤溶液储存部分和引入所述提取部分中捕获的所述基因的反应部分，其中从所述洗涤溶液引入所述洗涤溶液的流体通道 获得了与从所述注入口更远的区域连接到从所述基因提取部引入含有所述样品的溶液的区域。

公开(公告)号：US4983038A

公开(公告)日：1991-01-08

申请号：US178651

申请日：1988-04-07

申请人： Hiroshi Ohki ,  Ryo Miyake ,  Isao Yamazaki ,  Fujiya Takahata

发明人： Hiroshi Ohki ,  Ryo Miyake ,  Isao Yamazaki ,  Fujiya Takahata

IPC分类号： B01F13/00 ,  G01N15/14

CPC分类号： G01N15/1404 ,  B01F13/0062

摘要： A sheath flow type flow-cell device for photo-particle-analyzer comprises a substantially flat top surface, at least one first inlet for sheath fluid, at least one first flow passage communicated with the at least one first inlet and contracted toward downstream to be a straight capillary flow passage, a discharge port provided at a terminal end of the straight capillary flow passage, a second inlet for sample fluid, a second flow passage for sample fluid communicated with the second inlet and contracted toward downstream, and coupling portions for sealingly coupling with the particle photo-analyzer. The second flow passage is opened within the at least one first flow passage so as to keep a part of the at least one first flow passage above and below an opening of the second flow passage. The opening is faced in the same direction as the straight capillary flow passage. A wall portion on which the opening locates is rounded. The wall portion is further chamfered and a pair of projections are extended from the wall portion.