公开(公告)号：US07413713B2

公开(公告)日：2008-08-19

申请号：US10283215

申请日：2002-10-30

Applicant: Tadashi Sano ,  Ryo Miyake ,  Akira Koide ,  Norihide Saho ,  Akiomi Kono ,  Takeshi Harada

Inventor： Tadashi Sano ,  Ryo Miyake ,  Akira Koide ,  Norihide Saho ,  Akiomi Kono ,  Takeshi Harada

IPC: B01J10/00 ,  B01J10/02 ,  B01J12/00 ,  B01J12/02 ,  B01J14/00

CPC classification number: B01F15/00149 ,  B01F3/04503 ,  B01F5/0471 ,  B01F13/0059 ,  B01F15/00123 ,  B01F15/00344 ,  B01J4/001 ,  B01J10/002 ,  B01J14/00 ,  Y10T436/11 ,  Y10T436/117497 ,  Y10T436/118339 ,  Y10T436/25 ,  Y10T436/2575 ,  Y10T436/25875

Abstract: A reaction apparatus comprises a first supply flow channel having a fine flow channel cross sectional area for a liquid pressurized by a pressurizing device, a gas supply flow channel having a fine flow channel cross sectional area for supplying a gas, a two-phase flow channel having a fine flow channel cross sectional area in communication with a joined portion for the first supply flow channel and the second supply flow channel for flowing a gas/liquid two-phase fluid, a gas bubble reaction flow channel in communication with the exit of the gas/liquid two-phase channel and having a flow channel cross sectional area larger than that of the gas/liquid two-phase flow channel, and a liquid discharge flow channel for discharging the liquid in the gas bubble reaction flow channel. Therefore, in the reaction apparatus, a stable mixing ratio of a gas to a liquid can be obtained and the mixing speed of the gas to the liquid is increased.

Abstract translation: 反应装置包括：第一供给流路，其具有用于由加压装置加压的液体的细流路截面积;气体供给流路，具有用于供给气体的细流路截面积;二相流路 具有与用于第一供给流动通道的接合部分和用于使气体/液体两相流体流动的第二供应流动通道的细流动通道横截面积，与气体/液体两相流体流动的气泡反应流动通道， 气体/液体两相通道，并且具有大于气/液二相流动通道的流动通道横截面积，以及用于排出气泡反应流动通道中的液体的液体排出流动通道。 因此，在反应装置中，可以获得气体与液体的稳定的混合比，并且气体与液体的混合速度提高。

公开(公告)号：US20070059736A1

公开(公告)日：2007-03-15

申请号：US11450366

申请日：2006-06-12

Applicant: Hisao Saito ,  Yasuhiko Sasaki ,  Ryo Miyake

Inventor： Hisao Saito ,  Yasuhiko Sasaki ,  Ryo Miyake

IPC: C12Q1/68 ,  C12M1/34

CPC classification number: B01L3/502715 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/0887 ,  G01N1/2813 ,  G01N2001/2833

Abstract: A bio-analysis chip which is convenient in use and can promptly detect microbes with high accuracy. The bio-analysis chip comprises a collection member for collecting microbes in the atmosphere with the microbes adhering to the collection member, and a substrate in the form of a thin plate on which the collection member is mounted. The substrate has a collection member receiving section in which the collection member is placed, and a plurality of reagent reservoirs in which reagents for treating and analyzing the microbes are stored. The plurality of reagent reservoirs are connected to the collection member receiving section.

Abstract translation: 一种生物分析芯片，使用方便，可以高精度地及时检测微生物。 生物分析芯片包括收集构件，用于在微生物粘附到收集构件的情况下收集大气中的微生物，以及薄板形式的基板，收集构件安装在该基板上。 基板具有收集部件收纳部，收纳部件被放置在该收集部件收纳部中，并存储有用于处理和分析微生物的试剂的多个试剂储存器。 多个试剂储存器连接到收集构件接收部分。

公开(公告)号：US20070009387A1

公开(公告)日：2007-01-11

申请号：US11522379

申请日：2006-09-18

Applicant: Hajime Katou ,  Ryo Miyake ,  Hiroyasu Uchida ,  Katsuhiro Kambara ,  Takenori Okusa ,  Shigenori Watari ,  Yoichiro Suzuki ,  Tomonori Mimura ,  Miki Taki ,  Akira Inagaki

Inventor： Hajime Katou ,  Ryo Miyake ,  Hiroyasu Uchida ,  Katsuhiro Kambara ,  Takenori Okusa ,  Shigenori Watari ,  Yoichiro Suzuki ,  Tomonori Mimura ,  Miki Taki ,  Akira Inagaki

IPC: G01N33/00

CPC classification number: G01N35/1002 ,  B01F11/0283 ,  B01F2215/0037 ,  G01N35/025 ,  G01N2035/00554 ,  Y10S707/962 ,  Y10S707/99933 ,  Y10S707/99942 ,  Y10S707/99943 ,  Y10S707/99956

Abstract: A chemical analysis apparatus in which a sample to be analyzed and a reagent are placed into a reaction container, and sound waves are irradiated to said reaction container so as to agitate them, wherein said chemical analysis apparatus comprises a piezoelectric element producing said sound waves, and drivers for driving said piezoelectric element, said sound waves being intermittently irradiated into said reaction container.

Abstract translation: 一种化学分析装置，其中将待分析样品和试剂置于反应容器中，并且将声波照射到所述反应容器以搅拌它们，其中所述化学分析装置包括产生所述声波的压电元件， 以及用于驱动所述压电元件的驱动器，所述声波被间歇地照射到所述反应容器中。

公开(公告)号：US20050087562A1

公开(公告)日：2005-04-28

申请号：US10855431

申请日：2004-05-28

Applicant: Akira Koide ,  Ryo Miyake ,  Yasuo Ito ,  Yoshishige Endo

Inventor： Akira Koide ,  Ryo Miyake ,  Yasuo Ito ,  Yoshishige Endo

IPC: A61K8/02 ,  A61K8/00 ,  B01F5/04 ,  B01F5/06 ,  B01F13/00 ,  B01F13/10 ,  B65B3/26 ,  B65C3/08 ,  B65C9/46 ,  B67C3/02 ,  B67D1/00 ,  B67D7/02 ,  B67D7/74 ,  B67D1/16

CPC classification number: B01F13/0066 ,  B01F5/0453 ,  B01F5/0456 ,  B01F5/0458 ,  B01F5/0475 ,  B01F5/0646 ,  B01F5/0647 ,  B01F13/1055 ,  B01F2215/0031 ,  B65C3/08 ,  B65C9/46 ,  B67D1/0044 ,  B67D1/005 ,  B67D7/02 ,  B67D7/743

Abstract: A mixed liquid manufacturing apparatus comprises: an information input unit, in which information of an object, to which a mixed liquid is offered, is input; a material storage system that stores a plurality of materials for a mixed liquid; a product information system that selects kinds and quantities of the stored materials on the basis of the input information of the object, to which a mixed liquid is offered; a liquid transfer unit, by which the selected materials are taken out from the material storage system; a mixing unit, in which the materials supplied from the liquid transfer unit are mixed; an injection unit, by which the mixed liquid is injected into a mixed liquid container; an input unit, by which matters being declared on a label of the mixed liquid container are input; and a label formation unit, in which the input matters are printed on the label and the label is stuck on the mixed liquid container, and wherein the label formation unit begins printing before the injection unit completes injection of the mixed liquid into the container.

Abstract translation: 混合液体制造装置包括：信息输入单元，其中输入有提供混合液体的物体的信息; 存储用于混合液体的多种材料的材料储存系统; 产品信息系统，其基于提供混合液体的对象的输入信息来选择所存储的材料的种类和数量; 液体转移单元，通过所述液体转移单元将所选择的材料从所述材料储存系统中取出; 混合单元，其中从所述液体转移单元供应的材料混合; 注射单元，通过该注射单元将混合液体注入混合液体容器中; 输入在混合液体容器的标签上声明事项的输入单元; 以及标签形成单元，其中将输入物品印刷在标签上并且标签粘贴在混合液体容器上，并且其中标签形成单元在注射单元完成将混合液体注入容器之前开始印刷。

公开(公告)号：US20050060599A1

公开(公告)日：2005-03-17

申请号：US10901965

申请日：2004-07-30

Applicant: Hisao Inami ,  Yasuhiko Sasaki ,  Hajime Katou ,  Ryo Miyake

Inventor： Hisao Inami ,  Yasuhiko Sasaki ,  Hajime Katou ,  Ryo Miyake

IPC: G01N33/50 ,  G01N21/27 ,  G01N35/00 ,  G06F11/00 ,  G06F11/273 ,  G06F19/18 ,  G06Q50/00 ,  G06Q50/10 ,  G06Q50/22

CPC classification number: G06F11/2294

Abstract: There is provided a group of testing apparatuses that realizes high-level testing and high quality medical treatment by conducting tests using apparatuses and facilities that are located in a distributed condition. A distributed testing apparatus is configured to be connectable to a network system to which a host testing apparatus is connected, wherein the distributed testing apparatus has a testing part that assays genetic information of a specimen, a transmission part that transmits test results information of the testing part and a specimen ID corresponding to the specimen to the host testing apparatus through the network, a receiver part that receives through the network assessment information from the host testing apparatus that corresponds to the transmitted test results information, and an output part that outputs the received information.

Abstract translation: 提供了一组通过使用位于分布状态的设备和设施进行测试来实现高水平测试和高质量医疗的测试装置。 分布式测试装置被配置为可连接到主机测试设备连接到的网络系统，其中分布式测试设备具有测试样本的遗传信息的测试部分，传送测试结果信息的传输部分 通过网络向主机测试装置对应于样本的部分和样本ID，通过来自主机测试装置的与所发送的测试结果信息相对应的网络评估信息接收的接收机部分和输出所接收到的测试结果信息的输出部分 信息。

公开(公告)号：US06852282B2

公开(公告)日：2005-02-08

申请号：US10121734

申请日：2002-04-15

Applicant: Ryo Miyake ,  Naruo Watanabe ,  Hajime Katou ,  Takao Terayama ,  Yasushi Nomura ,  Hiroshi Mitsumaki

Inventor： Ryo Miyake ,  Naruo Watanabe ,  Hajime Katou ,  Takao Terayama ,  Yasushi Nomura ,  Hiroshi Mitsumaki

IPC: G01N35/04 ,  G01N35/00 ,  G01N35/02 ,  G01N35/10

CPC classification number: G01N35/1002 ,  G01N35/0099 ,  G01N35/028 ,  Y10T436/2575

Abstract: A chemical analyzer for measuring a concentration of components of a sample liquid, by mixing the sample liquid with reagents, so as to react the reagents upon the components thereof, includes a carrier having an introducing portion through which the sample liquid is injected, passages for distributing the sample liquid injected from the introducing portion, and plural reactor portions which hold the sample liquid therein to be mixed with the reagent, thereby to react. A movable driver portion is provided on which the carrier is mounted and a reagent charging device is provided for ejecting the reagents which are different for the respective plural reactor portions of the carrier, sequentially. Further, a detector is provided for detecting the components after mixing the reagents with the sample liquid.

Abstract translation: 一种用于测量样品液体组分浓度的化学分析仪，通过将样品液体与试剂混合以使试剂与其组分反应，包括具有引入部分的载体，通过该引入部分注入样品液体，通道用于 分配从引入部分注入的样品液体，以及将样品液体保持在其中以与试剂混合的多个反应器部分，从而进行反应。 提供了可移动的驱动器部分，其上安装有载体，并且提供了试剂充电装置，用于顺序地喷射对于载体的各个反应器部分不同的试剂。 此外，提供了一种用于在将试剂与样品液体混合之后检测组分的检测器。

公开(公告)号：US5690895A

公开(公告)日：1997-11-25

申请号：US761143

申请日：1996-12-06

Applicant: Masaetsu Matsumoto ,  Isao Yamazaki ,  Ryo Miyake ,  Masaharu Ishii ,  Ryohei Yabe ,  Hiroshi Ohki ,  Hideyuki Horiuchi ,  Shinichi Sakuraba

Inventor： Masaetsu Matsumoto ,  Isao Yamazaki ,  Ryo Miyake ,  Masaharu Ishii ,  Ryohei Yabe ,  Hiroshi Ohki ,  Hideyuki Horiuchi ,  Shinichi Sakuraba

IPC: G01N15/00 ,  G01N15/02 ,  G01N15/06 ,  G01N15/14 ,  G01N21/05 ,  G01N33/49

CPC classification number: G01N21/05 ,  G01N15/1404 ,  G01N2021/0346

Abstract: A flow cell apparatus, useful in an apparatus for measuring particles suspended in a liquid, comprises a sample liquid, supply device, a sheath liquid supply device, a flow cell which has a flow passage passing through a transparent measuring portion, and a nozzle for causing the sample liquid, from the supply device to flow in the flow passage of the flow cell. The nozzle has at least one discharge port which is disposed in the flow passage in a spaced relation from the inner wall of the flow cell flow passage. The sheath liquid supply device causes the sheath liquid to flow around the nozzle discharge port and surround the sample liquid flow to form a sheath flow. The flow passage of the flow cell and the nozzle are so formed as to ensure a sample liquid flow of a fixed width through the measuring portion. A stable sample flow having a fixed width can be formed in the measuring portion even when the flow is at a high velocity, and particles in the sample liquid can efficiently be photographed with high accuracy.

Abstract translation: 一种用于测量悬浮在液体中的颗粒的装置中的流动池装置，包括样品液体，供给装置，皮肤液体供应装置，具有通过透明测量部分的流动通道的流动池，以及用于 使来自供给装置的样品液体流入流动池的流路。 喷嘴具有至少一个排出口，该排出口以与流动池流动通道的内壁隔开的关系设置在流动通道中。 皮肤液体供给装置使皮肤液体在喷嘴排出口周围流动并且围绕样品液体流动形成鞘流。 流动池和喷嘴的流动通道形成为确保通过测量部分具有固定宽度的样品液体流动。 即使在流速高的情况下，也可以在测量部分形成具有固定宽度的稳定的样品流，并且可以高精度地有效地拍摄样品液体中的颗粒。

公开(公告)号：US4863264A

公开(公告)日：1989-09-05

申请号：US203457

申请日：1988-06-07

Applicant: Ryo Miyake ,  Hiroshi Ohki ,  Isao Yamazaki

Inventor： Ryo Miyake ,  Hiroshi Ohki ,  Isao Yamazaki

IPC: G01N15/14 ,  G01N33/48

CPC classification number: G01N15/1404 ,  G01N2015/1409 ,  G01N2015/1452

Abstract: A photoanalysis apparatus includes marker pouring device for pouring markers into one of sheath fluid and fluid carrying particles in a flow-cell device, second optical device for applying a light beam for correction to the markers in the flow-cell device to measure strength of fluorescence or light scattering caused by said markers to generate a signal for correction, second signal processing device for calculating from the signal for correction at least one of a difference in position between a center of the fluid carrying particles in the flow-cell device and a center of a light beam for examination and a difference in flow rate between a predetermined flow rate and an actual flow rate of the fluid carrying particles in the flow-cell device to generate correspondingly at least one of a first command signal for position correction and a second command signal for flow rate correction, and correspondingly at least one of first correcting device for shifting the center of the light beam for examination to the center of the flow of the fluid carrying particles in accordance with the first command signal and second correcting device for correcting the flow rate of the fluid carrying particles to the predetermined flow rate in accordance with the second command signal.

公开(公告)号：US08658102B2

公开(公告)日：2014-02-25

申请号：US12785835

申请日：2010-05-24

Applicant: Hajime Katou ,  Ryo Miyake ,  Hiroyasu Uchida ,  Katsuhiro Kambara ,  Takenori Okusa ,  Shigenori Watari ,  Yoichiro Suzuki ,  Tomonori Mimura ,  Miki Taki ,  Akira Inagaki

Inventor： Hajime Katou ,  Ryo Miyake ,  Hiroyasu Uchida ,  Katsuhiro Kambara ,  Takenori Okusa ,  Shigenori Watari ,  Yoichiro Suzuki ,  Tomonori Mimura ,  Miki Taki ,  Akira Inagaki

IPC: B06B1/06

CPC classification number: G01N35/1002 ,  B01F11/0283 ,  B01F2215/0037 ,  G01N35/025 ,  G01N2035/00554 ,  Y10S707/962 ,  Y10S707/99933 ,  Y10S707/99942 ,  Y10S707/99943 ,  Y10S707/99956

Abstract: A chemical analysis apparatus comprising reaction containers containing therein a substance to be analyzed; an agitating mechanism spaced from the substance to be analyzed and agitating said substance to be analyzed with a liquid in said reaction container; and, a measuring portion for measuring physical properties of the substance to be analyzed, said agitating mechanism having a sound supply portion supplying sound waves to the substance to be analyzed, wherein said sound supply portion comprises a mechanism changing, in time, intensity of ultrasonic waves to be irradiated so as to apply pulsation to a swirl flow in the reaction container.

Abstract translation: 一种化学分析装置，包括含有待分析物质的反应容器; 与待分析物质间隔开的搅拌机构，并在所述反应容器中用液体搅拌待分析物质; 以及用于测量被分析物质的物理性质的测量部分，所述搅拌机构具有向待分析物质供应声波的声音供给部分，其中所述声音供应部分包括时间上改变超声波强度的机构 要被照射的波浪以便对反应容器中的涡流施加脉动。

公开(公告)号：US07118662B2

公开(公告)日：2006-10-10

申请号：US10041597

申请日：2002-01-10

Applicant: Hironobu Yamakawa ,  Ryo Miyake ,  Yasuhiko Sasaki ,  Akira Koide

Inventor： Hironobu Yamakawa ,  Ryo Miyake ,  Yasuhiko Sasaki ,  Akira Koide

IPC: G01N27/447 ,  G01N27/26

CPC classification number: G01N27/44721 ,  G01N27/44791

Abstract: The windows 5a, 5b are configured so that the thickness of the upper and lower parts of the substrate formed therein with the channels becomes thinner in these parts than in other parts. An air space is defined in the vicinity of the one side wall of the channel within a part where the first outgoing window 5a is formed, so as to serve as a window, and the second outgoing window 5b has a shape such as to be recessed inward from the one side wall of the planar plate 10, in comparison with the other part thereof. Further, the fluorescence transmission path 6b is also formed on opposite sides with air spaces. It is noted that a rod-like fiber or the like may be embedded in the planar plate 10 on the outgoing side of the planar plate 10 at the time of forming the separation channel 21 and the like.

Abstract translation: 窗口5a，5b构造成使得在其中形成有通道的基板的上部和下部的厚度在这些部分比在其它部分中更薄。 在形成第一输出窗口5a的部分内的通道的一个侧壁的附近限定空气空间，以便用作窗口，并且第二出口窗口5b具有如下形状： 与平板10的一个侧壁向内凹入，与其他部分相比较。 此外，荧光传输路径6b也形成在具有空气空间的相对侧上。 注意，在形成分离通道21等时，可以在平板10的出口侧的平板10中嵌入棒状纤维等。