公开(公告)号：US3965106A

公开(公告)日：1976-06-22

申请号：US423981

申请日：1973-12-12

申请人： Isamu Maruyama ,  Masaru Nakao ,  Kikuo Sasajima ,  Shigeho Inaba ,  Hisao Yamamoto

发明人： Isamu Maruyama ,  Masaru Nakao ,  Kikuo Sasajima ,  Shigeho Inaba ,  Hisao Yamamoto

IPC分类号： C07D295/08 ,  C07D211/52 ,  C07D295/092

CPC分类号： C07D295/088 ,  C07D211/52

摘要： A 3-phenoxypropylamine derivative of the formula: ##SPC1##Wherein Y is ##SPC2##(wherein R.sub.1 is a halogen atom or a trifluoromethyl group) or ##SPC3##(wherein R.sub.2 is a lower alkyl group) and its pharmaceutically acceptable salts which are useful as central nervous system depressing agents.

摘要翻译： 下式的3-苯氧基丙胺衍生物：

公开(公告)号：US4032573A

公开(公告)日：1977-06-28

申请号：US659197

申请日：1976-02-19

申请人： Shinichi Kaneko, deceased ,  Tsuyoshi Kobayashi ,  Yoshiaki Takebayashi ,  Shigeho Inaba ,  Hisao Yamamoto

发明人： Shinichi Kaneko, deceased ,  Tsuyoshi Kobayashi ,  Yoshiaki Takebayashi ,  Shigeho Inaba ,  Hisao Yamamoto

IPC分类号： C07C237/00 ,  C07C103/50

CPC分类号： C07C237/00 ,  Y10S514/818 ,  Y10S514/821

摘要： Ortho-acylated anilide derivatives represented by the formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are each C.sub.1 - .sub.3 alkyl, and n is 1 or 2, and salts thereof.

公开(公告)号：US4012515A

公开(公告)日：1977-03-15

申请号：US600119

申请日：1975-07-29

申请人： Junki Katsube ,  Masaru Nakao ,  Kikuo Sasajima ,  Isamu Maruyama ,  Masaharu Takayama ,  Keiichi Ono ,  Shigenari Katayama ,  Yoshihiro Tanaka ,  Shigeho Inaba ,  Hisao Yamamoto

发明人： Junki Katsube ,  Masaru Nakao ,  Kikuo Sasajima ,  Isamu Maruyama ,  Masaharu Takayama ,  Keiichi Ono ,  Shigenari Katayama ,  Yoshihiro Tanaka ,  Shigeho Inaba ,  Hisao Yamamoto

IPC分类号： C07D211/52 ,  C07D295/084 ,  C07D295/108

CPC分类号： C07D295/108 ,  C07D211/52 ,  C07D295/092

摘要： Novel olefinic aryl ketone compounds of the formula: ##STR1## wherein R.sup.1 is hydrogen, halogen, C.sub.1.sub.-4 alkyl, or C.sub.1.sub.-4 alkoxy, R.sup.2 is hydrogen or halogen, and R.sup.3 and R.sup.4 are each hydrogen, halogen, C.sub.1.sub.-4 alkyl or trifluoromethyl, and their non-toxic salts, which possess various useful pharmacological activities and can be produced by reaction of an acetylenic alcohol of the formula: ##STR2## wherein R.sup.1 and R.sup.2 are each as defined above, with formaldehyde and an amine of the formula: ##STR3## wherein R.sup.3 and R.sup.4 are each as defined above; reduction of the resultant acetylenic aryl alcohol; and oxidation of the resultant olefinic aryl alcohol.

摘要翻译： 新颖的下式的烯属芳基酮化合物：其中R 1是氢，卤素，C 1-4烷基或C 1-4烷氧基，R 2是氢或卤素，R 3和R 4各自是氢，卤素，C 1-4烷基 或三氟甲基及其无毒盐，其具有各种有用的药理活性，并且可以通过下式的炔属醇与其中的甲醛和胺反应制备下式的炔属醇：其中R1和R2各自如上定义 式：其中R 3和R 4各自如上所定义; 所得炔属芳基醇的还原; 和所得烯属芳基醇的氧化。

公开(公告)号：US4009275A

公开(公告)日：1977-02-22

申请号：US553932

申请日：1975-02-28

申请人： Isamu Maruyama ,  Masaru Nakao ,  Kikuo Sasajima ,  Shigeho Inaba ,  Hisao Yamamoto

发明人： Isamu Maruyama ,  Masaru Nakao ,  Kikuo Sasajima ,  Shigeho Inaba ,  Hisao Yamamoto

IPC分类号： A61K31/445 ,  C07D401/04

CPC分类号： C07D401/04 ,  A61K31/445

摘要： Phenoxypropylamine derivatives of the formula: ##STR1## (in which R.sub.2 is a halogen atom or a trifluoromethyl group) and R.sub.1 is a halogen atom or a C.sub.1 -C.sub.4 alkyl or C.sub.2 -C.sub.4 alkenyl group, and their pharmaceutically acceptable salts, which are useful as neuroleptic agents and can be prepared by reacting a compound of the formula: ##STR2## wherein X is a halogen atom and R.sub.1 is as defined above with a compound of the formula:H-Ywherein Y is as defined above.

摘要翻译： 下式的苯氧丙胺衍生物：其中R 2为卤原子或三氟甲基，R 1为卤素原子或C 1 -C 4烷基或C 2 -C 4烯基， 药学上可接受的盐，其可用作抗精神病药，并且可以通过使下式化合物与下式化合物反应来制备：其中X是卤素原子，R 1如上定义;

公开(公告)号：US4001412A

公开(公告)日：1977-01-04

申请号：US575042

申请日：1975-05-06

申请人： Toshiyuki Hirohashi ,  Hiromi Sato ,  Shigeho Inaba ,  Hisao Yamamoto

发明人： Toshiyuki Hirohashi ,  Hiromi Sato ,  Shigeho Inaba ,  Hisao Yamamoto

IPC分类号： C07D495/04 ,  A61K31/495

CPC分类号： C07D495/04

摘要： 1-Substituted-1,2-dihydrothieno[2,3-d]-pyrimidin-2-ones of the formula, ##STR1## wherein R is lower alkyl or cyclopropylmethyl, R.sub.1 is halogen, lower alkyl or nitro, R.sub.2 is hydrogen or lower alkyl and R.sub.3 is hydrogen or halogen, are obtained by treating a trihaloacetamidothiophene derivative with ammonia. These compounds have excellent pharmacological activities such as uricosuric activity.

公开(公告)号：US3966939A

公开(公告)日：1976-06-29

申请号：US558655

申请日：1975-03-17

申请人： Kenji Kobayashi ,  Toshitsugu Fukumaru ,  Hiroyuki Mizote ,  Shigeho Inaba ,  Hisao Yamamoto

发明人： Kenji Kobayashi ,  Toshitsugu Fukumaru ,  Hiroyuki Mizote ,  Shigeho Inaba ,  Hisao Yamamoto

IPC分类号： A61K31/395 ,  A61K31/485

CPC分类号： A61K31/395

摘要： Novel 2-substituted 6,7-benzomorphan derivatives of the formula: ##SPC1##And acid addition salts thereof, which are useful as non-addicting analgesics, pain relieving agents and antitussives and can be prepared by reacting 6,7-benzomorphan derivatives of the formula: ##SPC2##With the reactive derivatives of alcohols of the formula: ##EQU1## [wherein R is a hydrogen atom, a hydroxyl group, an alkoxy group or an alkanoyloxy group; R.sub.1 is a hydrogen atom, an alkyl group, an alkoxyalkyl group or a substituted or unsubstituted aryl group; R.sub.3 is a hydrogen atom or a hydroxyl group; R.sub.4 is a hydrogen atom, an alkyl group or a substituted or unsubstituted aryl group, or R.sub.3 and R.sub.4 may form an alkylidene group or a carbonyl group together with the carbon atom to which these substituents are bonded; R.sub.2, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9 and R.sub.10 are each a hydrogen atom or an alkyl group; A is an alkylene group; and m is an integer of 0 to 2].

摘要翻译： 具有下式的新颖的2-取代的6,7-苯并吗啉衍生物：

公开(公告)号：US3961066A

公开(公告)日：1976-06-01

申请号：US456268

申请日：1974-03-29

申请人： Toshitsugu Fukumaru ,  Kenji Kobayashi ,  Hiroyuki Mizote ,  Shigeho Inaba ,  Hisao Yamamoto

发明人： Toshitsugu Fukumaru ,  Kenji Kobayashi ,  Hiroyuki Mizote ,  Shigeho Inaba ,  Hisao Yamamoto

IPC分类号： A61K31/47 ,  A61P25/04 ,  C07D211/70 ,  C07D211/82 ,  C07D221/26

CPC分类号： C07D211/70 ,  C07D221/26 ,  Y02P20/55 ,  Y10S514/849

摘要： A novel 2-substituted-6,7-benzomorphan derivative of the formula: ##SPC1##And its acid addition salts, which are useful as non-addicting analgesics and antitussives and can be prepared by reacting a 2-unsubstituted-6,7-benzomorphan derivative of the formula: ##SPC2##With the reactive derivative of an alcohol of the formula:HOA',optionally followed by elimination of the protective group in the resulting product, wherein R.sub.1 is hydrogen, lower alkyl or acyl; R.sub.2 and R.sub.3 are each lower alkyl; A is lower alkyl, cyano(lower)alkyl, benzoyl(lower)alkyl, ar(lower)alkyl, lower alkenyl or cyclo(lower)alkyl(lower)alkyl; and A' is a group as mentioned in A or benzoyl(lower)alkyl of which the carbonyl group is masked with a suitable protective group.

摘要翻译： 一种下式的新型2-取代-6,7-苯并吗啉衍生物：

公开(公告)号：US08669040B2

公开(公告)日：2014-03-11

申请号：US12320226

申请日：2009-01-22

申请人： Hiroshi Tashiro ,  Atsushi Sugasaki ,  Hisao Yamamoto

发明人： Hiroshi Tashiro ,  Atsushi Sugasaki ,  Hisao Yamamoto

IPC分类号： B41N1/00 ,  B41F33/00 ,  G03F7/00 ,  G03F7/26

CPC分类号： B41C1/05

摘要： The invention provides a method of manufacturing a relief printing plate having at least engraving an area which is in a relief forming layer of a relief printing plate precursor for laser engraving and is to be exposed by scanning exposure using a fiber-coupled semiconductor laser which emits laser beam with a wavelength of 700 nm to 1,300 nm. The relief printing plate precursor has at least a relief forming layer provided over a support, and the relief forming layer contains at least a binder polymer and a photo-thermal conversion agent. The invention further provides a relief printing plate precursor for laser engraving which can be used in the method of manufacturing a relief printing plate.

摘要翻译： 本发明提供一种制造凸版印刷版的方法，该凸版印刷板至少雕刻在用于激光雕刻的浮雕印版前体的凸版形成层中的区域，并且通过使用发射的光纤耦合半导体激光器的扫描曝光来曝光 波长为700nm至1300nm的激光束。 凸版印刷版前体至少具有设置在载体上的浮雕形成层，凸版形成层至少含有粘合剂聚合物和光热转换剂。 本发明还提供了可用于制造凸版印刷版的方法中的用于激光雕刻的浮雕印版前体。

公开(公告)号：US07741005B2

公开(公告)日：2010-06-22

申请号：US11730411

申请日：2007-04-02

申请人： Hiromitsu Yanaka ,  Shigeo Koizumi ,  Hisao Yamamoto

发明人： Hiromitsu Yanaka ,  Shigeo Koizumi ,  Hisao Yamamoto

IPC分类号： G03C1/00 ,  G03C1/36

CPC分类号： B41C1/1016 ,  B41C2201/02 ,  B41C2201/10 ,  B41C2201/14 ,  B41C2210/04 ,  B41C2210/06 ,  B41C2210/22 ,  B41C2210/24

摘要： The present invention provides a planographic printing plate precursor, including: a support; and a photosensitive layer containing a polymerizable compound; an oxygen barrier layer; and a protective layer containing a filler (preferably an organic resin particle), the layers being formed in this order on the support. The present invention also provides a stack of planographic printing plate precursors, produced by stacking the planographic printing plate precursors with the photosensitive layer side outermost layer and the support side rear surface of the adjacent plate precursor in direct contact with each other.

摘要翻译： 本发明提供一种平版印刷版原版，包括：载体; 和含有可聚合化合物的感光层; 氧阻隔层; 和含有填料（优选有机树脂颗粒）的保护层，这些层依次形成在载体上。 本发明还提供了通过将平版印刷版前体与感光层侧最外层和邻近的板前体的支撑侧后表面彼此直接接触而堆叠制成的平版印刷版前体的叠层。

公开(公告)号：US20080113296A1

公开(公告)日：2008-05-15

申请号：US11934537

申请日：2007-11-02

申请人： Hisao Yamamoto ,  Akihiro Endo

发明人： Hisao Yamamoto ,  Akihiro Endo

IPC分类号： G11B7/24

CPC分类号： G03F7/092 ,  B41C1/1016 ,  B41C2201/02 ,  B41C2201/06 ,  B41C2201/10 ,  B41C2201/12 ,  B41C2201/14 ,  B41C2210/04 ,  B41C2210/06 ,  B41C2210/22 ,  B41C2210/24 ,  B41C2210/262

摘要： The invention provides a planographic printing plate precursor that is writable by laser exposure and is composed of a support, a photosensitive recording layer formed on the support, and a backcoat layer containing an epoxy resin, the backcoat layer being formed on the side of the support opposite to the photosensitive recording layer side; and a stack of the planographic printing plate precursors. According to the invention, scratches on the photosensitive recording side of the planographic printing plate precursor can be prevented when brought into contact with another planographic printing plate precursor in the stack without interleaving slip sheets, and productivity in a plate making process can be improved.

摘要翻译： 本发明提供一种通过激光曝光可写入的平版印刷版原版，由载体，形成在载体上的感光记录层和含有环氧树脂的背涂层组成，背涂层形成在载体侧 与感光记录层侧相对; 和一系列平版印刷版前体。 根据本发明，当与叠片中的其它平版印刷版前体接触而不会交错滑片时，可以防止平版印刷版原版的感光记录面上的划痕，并且可以提高制版过程中的生产率。