摘要:
The present invention provides a system and method for dynamically integrating remote Portal fragments into a local Portal while maintaining the look and feel of the local Portal by receiving Meta-information of the remote Portal fragment, integrating said Meta-information into the existing navigation tree of the local Portal resulting in an new navigation tree, traversing the new navigation tree for rendering the integrated Portal page, identifying references in the new navigation tree for remote Portal fragments, establishing Communication with the remote Portal, and receiving and including remote Portal fragments into the local Portal page. The present invention secures a seamless integration of Portal fragments into the local Portal while maintaining the local Portal's look and feel.
摘要:
The present invention relates to substituted pyrimidines of formula I, their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases (CDKs) and hence their use in the treatment of proliferative disorders and/or viral disorders.
摘要:
The present invention relates to compounds of formula I or a pharmaceutically acceptable salt thereof wherein R2 is 2-hydroxymethylpyrrolidin-1-yl, or NHCH(R4)CH(R3)OH, wherein R3 is hydrogen or methyl and R4 is methyl, ethyl or isopropyl; R6 is 3-nitrophenylamino, 3,4-dimethoxybenzylamino, 3-iodobenzyl-amino, pyrid-2-yl-methylamino, pyrid-4-yl-methylamino or indan-5-amino; R9 is isopropyl or cyclopentanyl. In a further aspect, the invention relates to pharmaceutical compositions comprising said compounds, and the use thereof in treating antiproliferative disorders and or viral disorders.
摘要:
A process for the removal and recovery of quaternary salt (A) and base (D) from a reaction mixture is disclosed. The reaction mixture resulting from oxidative direct carbonylation contains in addition to (A) and (D), at least one hydroxyaromatic compound (B) and at least one reaction product (C) and optionally a solvent, and the process entails a) adding acid to the reaction mixture to cause conversion of (D) into a hydroxyaromatic compound (B2) b) separating the reaction mixture into b1.) that contains (C) and optionally (B) and/or (B2) and b2.) that contains (A) and optionally (B) and/or (B2), and c) reacting b1.) with a base (E) to re-form (D).
摘要:
The present invention provides a two-stage process for the production of polyester carbonates with aliphatic dicarboxylic acids, the polyester carbonates obtained thereby, a process for the production of extrudates and molded articles from the polyester carbonates, and the extrudates and molded articles obtained thereby.
摘要:
A thermoplastic molding composition comprising polycarbonate resin having improved mold release properties is disclosed the composition contain polycarbonate resin and 0.005 to 5.0% relative to the weight of the composition of at least one hydrocarbon in the form of C15-600-methyl-branched alkane. The hydrocarbon is characterized in that the weight proportion of its branches is 5 to 30 percent relative to the weight of carbons in the alkane chain.
摘要:
The invention relates to a housing consisting of two housing halves for a side channel compressor. The strength of such a housing can be appreciably increased in that the front wall (3) of each housing half (1) and (2) has formed on it at least two rings (4) and (5), spaced radially from one another and projecting axially relative to the front wall (3), and rib walls (7) extending in a spoke-like manner between these rings (4) and (5).
摘要:
The present invention relates to disulphide-cyclo-�H-Cys-Glu-Gln-Tyr-Cys-OH! and salts thereof which are useful in the treatment of blood clotting disorders.
摘要:
A compressor unit is provided, which has at least two side-channel compressors arranged axially next to one another, and in which housing halves within each compressor each have, on a housing wall extending between an axially extending hub extension and a housing protrusion caused by a side channel, an axial extension 11. Side-channel compressors of different sizes can be assembled into a unit by the fact that the axial extension extends in each case into the parting plane of the housing halves, and is in each case equipped with a centering rim, projecting beyond the parting plane that mates with a centering step provided on the axial extension of the adjacent housing half and standing back from the parting plane. The inner housing halves are attached to one another at the axial extensions. The outer housing halves are attached to the inner housing halves by the attachment elements introduced into the passthrough openings.
摘要:
In a wiper shaft bushing assembly with a washer jet for motor vehicle screens, in which the wiper shaft is guided in a wiper bushing and is surrounded by an elastic plastic sleeve in which a washer jet is located. The one-piece plastic sleeve surrounds the wiper bushing and the elongated wiper shaft preferably eccentrically. The sleeve has shaped in its wall located farthest from the wiper shaft a closed off liquid channel which is connected on the inner end to a lateral tube connection for connection to the washer pump and on its outer end to a ball socket for receiving a spherical directable nozzle body of the washer jet.