中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

57 records (took 0.022 seconds)

    Mass spectrometer
    42.
    发明授权
    Mass spectrometer 有权
    质谱仪

    公开(公告)号：US07622711B2

    公开(公告)日：2009-11-24

    申请号：US11574554

    申请日：2005-09-14

    Applicant: Jason Lee Wildgoose ,  Steven Derek Pringle ,  Kevin Giles ,  Robert Harold Bateman

    Inventor： Jason Lee Wildgoose ,  Steven Derek Pringle ,  Kevin Giles ,  Robert Harold Bateman

    IPC: B01D59/44

    CPC classification number: H01J49/005

    Abstract: A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator (3) arranged upstream of a collision or fragmentation cell (5). Ions are separated according to their ion mobility within the ion mobility spectrometer or separator (3). The kinetic energy of the ions exiting the ion mobility spectrometer or separator (3) is increased substantially linearly with time in order to optimize the fragmentation energy of ions as they enter the collision or fragmentation cell (5).

    Abstract translation: 公开了一种质谱仪，其包括设置在碰撞或破碎电池（5）的上游的离子迁移谱仪或分离器（3）。 离子在离子迁移谱仪或分离器（3）内根据其离子迁移率分离。 离子离子迁移谱仪或分离器（3）离子的动能随时间呈线性增加，以优化离子进入碰撞或破碎电池（5）时的碎裂能。

    Mass Spectrometer
    43.
    发明申请
    Mass Spectrometer 有权
    质谱仪

    公开(公告)号：US20090014641A1

    公开(公告)日：2009-01-15

    申请号：US12094561

    申请日：2006-12-07

    Applicant: Robert Harold Bateman ,  Kevin Giles ,  Steven Derek Pringle ,  Jason Lee Wildgoose

    Inventor： Robert Harold Bateman ,  Kevin Giles ,  Steven Derek Pringle ,  Jason Lee Wildgoose

    IPC: B01D59/44

    CPC classification number: G01N27/622 ,  H01J49/062

    Abstract: A closed-loop ion guide (1) is disclosed comprising a plurality of electrodes having apertures through which ions are transmitted in use. Ions are injected into the closed-loop ion guide (1) and may make several circuits of the closed-loop ion guide (1) before being ejected from the ion guide (1). In a mode of operation the ion guide (1) may be arranged to separate ions temporally according to their ion mobility.

    Abstract translation: 公开了一种闭环离子导向器（1），其包括具有孔的多个电极，在使用中通过该孔具有离子。 离子被注入到闭环离子导向器（1）中，并且可以在从离子导向器（1）喷射之前制造闭环离子导向器（1）的几个电路。 在操作模式中，离子导向器（1）可以被布置成根据离子迁移率暂时分离离子。

    Mass spectrometer
    45.
    发明授权
    Mass spectrometer 有权
    质谱仪

    公开(公告)号：US08952323B2

    公开(公告)日：2015-02-10

    申请号：US12092601

    申请日：2006-11-10

    Applicant: Robert Harold Bateman ,  Kevin Giles ,  Steven Derek Pringle ,  Jason Lee Wildgoose

    Inventor： Robert Harold Bateman ,  Kevin Giles ,  Steven Derek Pringle ,  Jason Lee Wildgoose

    IPC: H01J49/00 ,  G01N27/62 ,  H01J49/42

    CPC classification number: H01J49/004 ,  G01N27/622 ,  H01J49/0031 ,  H01J49/42

    Abstract: A mass spectrometer is disclosed comprising a first ion trap or ion guide (2), a single ion mobility spectrometer or separator stage (3) and a second ion trap or ion guide (4) arranged downstream of the ion mobility spectrometer or separator (3). In a mode of operation ions from the second ion trap or ion guide (4) are passed from the second ion trap or ion guide back upstream to the ion mobility spectrometer or separator (3).

    Abstract translation: 公开了一种质谱仪，其包括第一离子阱或离子导向器（2），单离子迁移谱仪或分离器级（3）和设置在离子迁移谱仪或分离器（3）的下游的第二离子阱或离子导向器 ）。 在操作模式中，来自第二离子阱或离子导向器（4）的离子从第二离子阱或离子导向器返回到离子迁移谱仪或分离器（3）的上游。

    Mass spectrometer
    47.
    发明授权
    Mass spectrometer 有权
    质谱仪

    公开(公告)号：US08519328B2

    公开(公告)日：2013-08-27

    申请号：US13435877

    申请日：2012-03-30

    Applicant: Kevin Giles ,  Martin Green ,  Jason Lee Wildgoose ,  Steven Derek Pringle

    Inventor： Kevin Giles ,  Martin Green ,  Jason Lee Wildgoose ,  Steven Derek Pringle

    IPC: H01J49/26

    CPC classification number: H01J49/427 ,  H01J49/4235

    Abstract: An ion guide or ion trap is disclosed having an entrance electrode and an exit electrode. The potential of the exit electrode is periodically dropped for a relatively short period of time allowing some ions to escape from the ion guide or ion trap via an aperture in the exit electrode. The period of time that the potential of the exit electrode is dropped for is progressively increased and ions emerge from the ion guide or ion trap in a mass to charge ratio dependent manner. The ion guide or ion trap may be operated as a mass separator or low resolution mass analyzer.

    Abstract translation: 公开了一种具有入口电极和出射电极的离子导向器或离子阱。 出口电极的电位周期性地下降相当短的时间段，允许一些离子通过出射电极的孔离开离子导向器或离子阱。 出口电极的电位下降的时间段逐渐增加，并且离子导向器或离子阱以质荷比依赖的方式出现离子。 离子导向器或离子阱可以作为质量分离器或低分辨率质量分析器来操作。

    Method of Mass Spectrometry and Mass Spectrometer Using Peak Deconvolution
    48.
    发明申请
    Method of Mass Spectrometry and Mass Spectrometer Using Peak Deconvolution 有权
    使用峰值去卷积的质谱法和质谱仪的方法

    公开(公告)号：US20130168546A1

    公开(公告)日：2013-07-04

    申请号：US13576344

    申请日：2011-02-14

    Applicant: Richard Denny ,  Keith Richardson ,  Martin Raymond Green ,  Steven Derek Pringle ,  Anthony James Gilbert ,  John Skilling ,  Jason Lee Wildgoose

    Inventor： Richard Denny ,  Keith Richardson ,  Martin Raymond Green ,  Steven Derek Pringle ,  Anthony James Gilbert ,  John Skilling ,  Jason Lee Wildgoose

    IPC: H01J49/00 ,  H01J49/40

    CPC classification number: H01J49/0036 ,  H01J49/40

    Abstract: A method of mass spectrometry is disclosed wherein a signal output from an ion detector is digitised by an Analogue to Digital Converter and is then deconvoluted to determine one or more ion arrival times and one more ion arrival intensities. The process of deconvoluting the ion signal involves determining a point spread function characteristic of an ion arriving at and being detected by the ion detector. A distribution of ion arrival times which produces a best fit to the digitised signal is then determined given that each ion arrival is assumed to produce a response given by the point spread function. A plurality of ion arrival times are then combined to produce a composite ion arrival time-intensity spectrum.

    Abstract translation: 公开了一种质谱法，其中从离子检测器输出的信号被模拟数字转换器数字化，然后进行解卷积，以确定一个或多个离子到达时间和一个离子到达强度。 去卷积离子信号的过程涉及确定到达并被离子检测器检测的离子的点扩散函数特征。 因此，假设每个离子到达产生由点扩散函数给出的响应，则确定产生与数字化信号最佳拟合的离子到达时间的分布。 然后将多个离子到达时间组合以产生复合离子到达时间强度谱。

    Mass spectrometer
    49.
    发明授权
    Mass spectrometer 有权
    质谱仪

    公开(公告)号：US08426802B2

    公开(公告)日：2013-04-23

    申请号：US12518291

    申请日：2007-12-12

    Applicant: Kevin Giles ,  Steven Derek Pringle ,  Jason Lee Wildgoose

    Inventor： Kevin Giles ,  Steven Derek Pringle ,  Jason Lee Wildgoose

    IPC: B01D59/44 ,  H01J49/00

    CPC classification number: G01N27/622 ,  G01N27/624 ,  H01J49/062 ,  H01J49/4235

    Abstract: A mass spectrometer is disclosed comprising a device which is operable in a first mode of operation to separate ions temporally according to their ion mobility by applying a continuous axial electric field. The device is also operable in a second mode of operation wherein ions are separated temporally according to the their mass to charge ratio by pulsing an applied axial electric field ON and OFF.

    Abstract translation: 公开了一种质谱仪，其包括可在第一操作模式中操作的装置，其通过施加连续的轴向电场根据其离子迁移率暂时分离离子。 该装置还可在第二操作模式中操作，其中通过脉冲施加的轴向电场ON和OFF，离子根据其质荷比暂时分离。

    Method of Screening a Sample for the Presence of One or More Known Compounds of Interest and a Mass Spectrometer Performing this Method
    50.
    发明申请
    Method of Screening a Sample for the Presence of One or More Known Compounds of Interest and a Mass Spectrometer Performing this Method 有权
    筛选样品以存在一种或多种已知化合物和进行该方法的质谱的方法

    公开(公告)号：US20120241602A1

    公开(公告)日：2012-09-27

    申请号：US13394089

    申请日：2010-09-06

    Applicant: Jeffrey Alan Goshawk ,  Steven Derek Pringle ,  Steve Smith

    Inventor： Jeffrey Alan Goshawk ,  Steven Derek Pringle ,  Steve Smith

    IPC: H01J49/26 ,  H01J49/40

    CPC classification number: H01J49/40 ,  H01J49/0027 ,  H01J49/004

    Abstract: A method of screening a sample for the presence of one or more known compounds of interest is disclosed. A fragmentation device is repeatedly switched between a fragmentation mode of operation and a non-fragmentation mode of operation. A determination is made whether a candidate parent ion of interest is present in a non-fragmentation data set and whether one or more corresponding fragment ions of interest are present in a fragmentation data set. A further determination is made to check if the candidate parent ion of interest and the one or more corresponding fragment ions of interest have substantially similar elution or retention times and/or ion mobility drift times.

    Abstract translation: 公开了筛选样品中存在一种或多种已知化合物的方法。 分段设备在分段操作模式和非分段操作模式之间重复切换。 确定感兴趣的候选母体离子是否存在于非碎裂数据集中，以及感兴趣的一个或多个相应的碎片离子是否存在于碎裂数据集中。 进一步确定检查感兴趣的候选亲本离子和感兴趣的一个或多个相应碎片离子是否具有基本相似的洗脱或保留时间和/或离子迁移率漂移时间。

Patent Agency Ranking