Polyethylene oxide-based films and drug delivery systems made therefrom
    43.
    发明授权
    Polyethylene oxide-based films and drug delivery systems made therefrom 有权
    聚环氧乙烷基薄膜和药物输送系统

    公开(公告)号:US08017150B2

    公开(公告)日:2011-09-13

    申请号:US12107389

    申请日:2008-04-22

    IPC分类号: A61K9/14

    摘要: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.

    摘要翻译: 本发明涉及其制备的薄膜产品及其制备方法,其表现出非自聚集均匀的异质性。 期望地,膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分,其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地,膜还含有药物和/或化妆品活性剂,其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10%。

    Polyethylene oxide-based films and drug delivery systems made therefrom
    45.
    发明授权
    Polyethylene oxide-based films and drug delivery systems made therefrom 有权
    聚环氧乙烷基薄膜和药物输送系统

    公开(公告)号:US07666337B2

    公开(公告)日:2010-02-23

    申请号:US10856176

    申请日:2004-05-28

    IPC分类号: B29C39/14

    摘要: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.

    摘要翻译: 本发明涉及其制备的薄膜产品及其制备方法,其表现出非自聚集均匀的异质性。 期望地,膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分,其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地,膜还含有药物和/或化妆品活性剂,其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10%。

    POLYETHYLENE OXIDE-BASED FILMS AND DRUG DELIVERY SYSTEMS MADE THEREFROM
    46.
    发明申请
    POLYETHYLENE OXIDE-BASED FILMS AND DRUG DELIVERY SYSTEMS MADE THEREFROM 有权
    聚乙烯氧化物膜和药物输送系统

    公开(公告)号:US20080260809A1

    公开(公告)日:2008-10-23

    申请号:US12107389

    申请日:2008-04-22

    IPC分类号: A61K9/70

    摘要: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.

    摘要翻译: 本发明涉及其制备的薄膜产品及其制备方法,其表现出非自聚集均匀的异质性。 期望地,膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分,其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地,膜还含有药物和/或化妆品活性剂,其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10%。

    Confectionery delivery system for anti-cholesterolemics
    50.
    发明授权
    Confectionery delivery system for anti-cholesterolemics 失效
    糖果交付系统用于抗胆固醇药

    公开(公告)号:US4882157A

    公开(公告)日:1989-11-21

    申请号:US258246

    申请日:1988-10-14

    IPC分类号: A61K9/00 A61K9/16 A61K9/50

    摘要: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.

    摘要翻译: 一种用于活性物质的可咀嚼递送系统,包括:(a)预先涂覆有至少一种选自卵磷脂,链长度为约4个碳以下的聚氧化烯,熔点为100℃的甘油酯的材料的活性物质。 或更少的分子量为3,700以下的聚亚烷基二醇,合成和天然蜡及其混合物; 和(b)糖果基质,其包括包含明胶和选自甘油及其低级烷基(C2-7)酯衍生物)的保湿剂材料的粘合剂体系; 甜味剂 和约1%至约30%重量的水。