公开(公告)号：US07570985B2

公开(公告)日：2009-08-04

申请号：US10288295

申请日：2002-11-06

Applicant: Naoyuki Takabayashi ,  Yutaka Fukushima

Inventor： Naoyuki Takabayashi ,  Yutaka Fukushima

IPC: A61B5/05

CPC classification number: G01R33/563 ,  A61B5/0263 ,  A61B5/0275 ,  A61B5/055 ,  G01R33/281 ,  G01R33/56308

Abstract: Monitor scans are performed before imaging scans with respect to a patient injected with a contrast agent. Magnetic resonance images of a plurality of slices of the patient are acquired, usually continuously, in the monitor scans. Projection images are generated from the magnetic resonance images for the plurality of slices, and these projection images are dynamically displayed images. The operator observes the monitor image and issues an instruction for imaging scans. Since a projection image is displayed as the monitor image, then even if a blood vessel is distributed over a three-dimensional area, the operator is still able to ascertain accurately the timing at which the contrast agent reaches the diagnostic region.

Abstract translation: 相对于注射造影剂的患者的成像扫描之前，进行监视扫描。 在监视器扫描中通常连续地获取患者的多个切片的磁共振图像。 从多个片的磁共振图像生成投影图像，这些投影图像是动态显示的图像。 操作员观察监视器图像并发出扫描成像指令。 由于投影图像被显示为监视器图像，所以即使血管分布在三维区域上，操作者还能够准确地确定造影剂到达诊断区域的时间。

公开(公告)号：US07559892B2

公开(公告)日：2009-07-14

申请号：US11298265

申请日：2005-12-09

Applicant: Doron Adler ,  Alex Zaretski

Inventor： Doron Adler ,  Alex Zaretski

IPC: A61B1/06

CPC classification number: A61B6/481 ,  A61B1/00096 ,  A61B1/00193 ,  A61B1/0623 ,  A61B1/0638 ,  A61B5/0084 ,  A61B5/0275 ,  A61B6/504 ,  H04N2005/2255 ,  H04N2209/047

Abstract: A medical wireless imaging device comprises an image sensor, a transmitter, a receiving device, and a plurality of light sources. The transmitter transmits data through a wireless communication link to a processing device. The receiving device wirelessly receives control data from a control unit. Each light source is configured to be individually controlled according to the control data. A reference image is stored for each light source. Intensities of each light source are calculated based on a reference image and on an input image.

Abstract translation: 医疗无线成像装置包括图像传感器，发射器，接收装置和多个光源。 发射机通过无线通信链路向处理设备发送数据。 接收设备从控制单元无线地接收控制数据。 每个光源被配置为根据控制数据单独控制。 为每个光源存储参考图像。 基于参考图像和输入图像计算每个光源的强度。

公开(公告)号：US20090076759A1

公开(公告)日：2009-03-19

申请号：US12236093

申请日：2008-09-23

Applicant: Hadassa DEGANI

Inventor： Hadassa DEGANI

IPC: G01F1/12

CPC classification number: G06T13/00 ,  A61B5/0263 ,  A61B5/0275 ,  A61B5/055 ,  G01R33/281 ,  G01R33/5601 ,  G01R33/56366 ,  G06T7/0004 ,  G06T7/0012 ,  G06T7/90 ,  G06T11/206 ,  G06T13/20 ,  G06T2207/10088 ,  G06T2207/10096 ,  G06T2207/10116 ,  G06T2207/30068 ,  G06T2207/30108 ,  G06T2210/24

Abstract: Apparatus and method for monitoring a system in which a fluid flows and which is characterized by a change in the system with time in space. A preselected place in the system is monitored to collect data at two or more time points correlated to a system event. The data is indicative of a system parameter that varies with time as a function of at least two variables related to system wash-in and wash-out behavior. A calibration map is made on a calculated basis with each pixel or voxel representative of a color hue indicative of wash-out behavior and a color intensity indicative of wash-in behavior. The calibration map serves as a criteria for selecting the time points. Software and a data processing system are provided to develop a color coded output map. The calibration map, the color coded output map and image of the preselected place are also novel implementations.

Abstract translation: 用于监测流体流动的系统的装置和方法，其特征在于系统随时间的变化。 监视系统中的预选位置以在与系统事件相关的两个或更多个时间点收集数据。 该数据表示系统参数随着时间而变化，其与至少两个与系统洗涤和洗出行为相关的变量的函数变化。 校准图是在计算的基础上进行的，每个像素或体素代表指示洗出行为的色调和指示洗涤行为的颜色强度。 校准图作为选择时间点的标准。 提供软件和数据处理系统以开发颜色编码的输出图。 校准图，颜色编码的输出图和预选地点的图像也是新颖的实现。

公开(公告)号：US20080119720A1

公开(公告)日：2008-05-22

申请号：US11941735

申请日：2007-11-16

Applicant: Timothy J. CARROLL ,  Wanyong SHIN ,  Jessy J. MOUANNES

Inventor： Timothy J. CARROLL ,  Wanyong SHIN ,  Jessy J. MOUANNES

IPC: A61B5/055

CPC classification number: A61B5/055 ,  A61B5/0263 ,  A61B5/0275 ,  G01R33/50 ,  G01R33/5601 ,  G01R33/5602 ,  G01R33/5616 ,  G01R33/5617 ,  G01R33/56366

Abstract: A method for calculating quantitative perfusion measurements using an MRI system includes a pulse sequence that acquires perfusion weighted images and additionally measures T1 values before and after the administration of a contrast agent. T1 values are measured by rapidly sampling a longitudinal relaxation curve and employed to determine the blood volume in tissue. A correction factor for the effect of water diffusion between blood vessels and the extravascular space is determined.

Abstract translation: 使用MRI系统计算定量灌注测量的方法包括获取灌注加权图像的脉冲序列，并另外测量施用造影剂之前和之后的T 1 N值。 通过快速采样纵向弛豫曲线并用于确定组织中的血容量来测量T 1值。 确定血管和血管外空间之间的水扩散效应的校正因子。

公开(公告)号：US20080058647A1

公开(公告)日：2008-03-06

申请号：US10565933

申请日：2004-07-13

Applicant: Sascha Kruger ,  Jorn Borgert

Inventor： Sascha Kruger ,  Jorn Borgert

IPC: A61B8/06 ,  A61B5/026 ,  A61B8/12

CPC classification number: A61B8/06 ,  A61B5/0261 ,  A61B5/0275 ,  A61B8/12 ,  G01F1/661 ,  G01F1/667 ,  G01F1/704 ,  G01P5/24 ,  G01P5/241 ,  G01P5/26 ,  G01S7/4813 ,  G01S7/4818 ,  G01S17/58

Abstract: The invention relates to a facility that can be used, in particular, to measure the flow conditions in a blood vessel. The facility comprises a catheter (16) having a bundle (15) of optical waveguides that connects control and measurement facilities (20) outside the body with an optical unit (10) at the catheter tip. The light (λK) generated by a cavitation light laser source (30) is beamed via the catheter (16) and the optical unit (10) into a focus region (2) in the vessel lumen, where it generates cavitation bubbles (3). The movement of the cavitation bubbles (3) with the blood flow is determined by the particle-measuring unit (20) that is based, for example, on phase-Doppler anemometry and/or the Doppler shift. As a result of suitable design of the optical unit (10), the focus region (2) can be displaced as desired radially and rotationally inside the vessel so that a vessel cross section can be scanned in a spatially resolved way. Furthermore, a spectral analysis of the light arriving from the focus region (2) is possible in order, for example, to analyze the chemical composition in this region. The reaching of the vessel wall (1) can be detected by the moving focus region (2) and used for a vessel measurement and/or to switch off the cavitation light laser (30).

Abstract translation: 本发明涉及一种能够特别用于测量血管中的流动状况的设备。 该设备包括具有光导管束（15）的导管（16），该导管将主体外部的控制和测量设备（20）与导管末端处的光学单元（10）连接。 通过空穴光激光源（30）产生的光（λN K）经由导管（16）和光学单元（10）射入血管内腔中的聚焦区域（2） 在那里它产生气蚀气泡（3）。 气蚀气泡（3）与血液流动的运动由例如基于相位多普勒血流计和/或多普勒频移的粒子测量单元（20）确定。 作为光学单元（10）的适当设计的结果，聚焦区域（2）可以根据需要在容器内径向和旋转地移位，使得可以以空间分辨的方式扫描容器横截面。 此外，从聚焦区域（2）到达的光的光谱分析是可能的，以便例如分析该区域中的化学成分。 血管壁（1）的到达可以由移动聚焦区域（2）检测并用于血管测量和/或关闭空化光激光器（30）。

公开(公告)号：US20080033314A1

公开(公告)日：2008-02-07

申请号：US11781536

申请日：2007-07-23

Applicant: Nikolai Krivitski

Inventor： Nikolai Krivitski

IPC: A61B5/028

CPC classification number: A61B5/0275

Abstract: A method for determining cardiac output in conjunction with flow through an extracorporeal circuit, wherein flow through an arterial line of the extracorporeal circuit is temporarily reversed and an indicator is passed through the cardiopulmonary circuit. A dilution curve is measured in the arterial line of the extracorporeal circuit during the reversed flow, and cardiac output is determined corresponding to the measured dilution curve.

Abstract translation: 一种用于通过体外循环流动测定心输出量的方法，其中通过体外循环的动脉线的流动被暂时反转，并且指示器通过心肺回路。 在逆流期间在体外循环的动脉线中测量稀释曲线，并且根据测量的稀释曲线确定心输出量。

公开(公告)号：US07210359B2

公开(公告)日：2007-05-01

申请号：US11456751

申请日：2006-07-11

Applicant: Nikolai M. Krivitski ,  Cornelis J. Drost

Inventor： Nikolai M. Krivitski ,  Cornelis J. Drost

IPC: G01F1/708

CPC classification number: A61B5/027 ,  A61B5/0215 ,  A61B5/0255 ,  A61B5/026 ,  A61B5/0275 ,  A61B5/6852 ,  A61M25/00 ,  G01F1/34 ,  G01F1/66 ,  G01F1/704 ,  G01F1/708 ,  G01F25/0007

Abstract: A method and apparatus for determining an initial flow rate in a conduit is disclosed. A known change is made to the flow to be measured, resulting changes (or values corresponding to these changes), or relative changes in the flow to be measured are monitored and the initial flow in the conduit is calculated from the value of the known change and monitored changes. Devices to practice the method include catheters having one or two sensors and one or two sites for introducing the volume change.

公开(公告)号：US20060183976A1

公开(公告)日：2006-08-17

申请号：US11298265

申请日：2005-12-09

Applicant: Doron Adler ,  Ofer Pillar ,  Alex Zaretski ,  Arie Blumenzweig

Inventor： Doron Adler ,  Ofer Pillar ,  Alex Zaretski ,  Arie Blumenzweig

IPC: A61B1/06 ,  A61B1/04

CPC classification number: A61B6/481 ,  A61B1/00096 ,  A61B1/00193 ,  A61B1/0623 ,  A61B1/0638 ,  A61B5/0084 ,  A61B5/0275 ,  A61B6/504 ,  H04N2005/2255 ,  H04N2209/047

Abstract: An endoscope having restricted dimensions and comprising at least one image gatherer, at least one image distorter and at least one image sensor shaped to fit within said limited dimensions, and wherein said image distorter is operable to distort an image received from said image gatherer so that the image is sensible at said shaped image sensor.

Abstract translation: 一种具有限制尺寸的内窥镜，包括至少一个图像采集器，至少一个图像变形器和至少一个成形为适合所述有限尺寸的图像传感器，并且其中所述图像变形器可操作以使从所述图像采集器接收的图像变形，使得 该图像在所述形状的图像传感器是明智的。

公开(公告)号：US20050178732A1

公开(公告)日：2005-08-18

申请号：US11104947

申请日：2005-04-13

Applicant: Nikolai Krivitski ,  David MacGibbon

Inventor： Nikolai Krivitski ,  David MacGibbon

IPC: A61B5/0275 ,  A61M1/16 ,  A61M1/36 ,  C02F1/00 ,  G01F1/00

CPC classification number: A61M1/3653 ,  A61B5/0275 ,  A61M1/16 ,  A61M1/3655 ,  A61M1/3658 ,  A61M1/3663 ,  A61M1/3669 ,  A61M1/367

Abstract: The measurement of blood flow in a dialysis shunt is obtained by injection of an indicator material into a venous line leading from dialysis equipment to the shunt. The blood flow in an arterial line leading from the shunt at a location downstream of the venous line to the dialysis equipment is monitored by an arterial line sensor for the presence of the indicator material. A detector connected to the sensor provides a dilution curve in response to the presence of the indicator material and the blood flow in the shunt is calculated from the area under the dilution curve. The locations of the arterial and venous lines in the shunt can be reversed to obtain a measurement of blood recirculation from the venous line into the arterial line.

Abstract translation: 通过将指示剂材料注射到从透析设备引导到分流器的静脉管线中，可以测量透析分流器中的血流量。 通过动脉线传感器监测从静脉线下游位置到分离设备的分流处的动脉线中的血液流动，以指示物质的存在。 连接到传感器的检测器响应于指示剂材料的存在而提供稀释曲线，并且根据稀释曲线下的面积计算分流器中的血流量。 分流器中的动脉和静脉线的位置可以反转，以获得从静脉线进入动脉线的血液再循环的测量。

公开(公告)号：US06915154B1

公开(公告)日：2005-07-05

申请号：US09744034

申请日：2000-08-11

Applicant: John C. Docherty ,  Mark Hewko ,  Gurpreet Mangat ,  Robert W. Flower ,  Seshadri M. Chari

Inventor： John C. Docherty ,  Mark Hewko ,  Gurpreet Mangat ,  Robert W. Flower ,  Seshadri M. Chari

IPC: A61B5/026 ,  A61B5/0275 ,  A61B6/00 ,  A61B5/05

CPC classification number: A61B5/0275 ,  A61B5/0261

Abstract: Method for assessing the patency of a patient's blood vessel, advantageously during or after treatment of that vessel by an invasive procedure, comprising administering a fluorescent dye to the patient; obtaining at least one angiographic image of the vessel portion; and evaluating the at least one angiographic image to assess the patency of the vessel portion. Other related methods are contemplated, including methods for assessing perfusion in selected body tissue, methods for evaluating the potential of vessels for use in creation of AV fistulas, methods for determining the diameter of a vessel, and methods for locating a vessel located below the surface of a tissue.

Abstract translation: 用于通过侵入性方法有利地在该容器处理期间或之后评估患者血管通畅的方法，包括向患者施用荧光染料; 获得血管部分的至少一个血管造影图像; 以及评估所述至少一个血管造影图像以评估血管部分的通畅。 预期了其它相关方法，包括评估所选体内组织灌注的方法，用于评估用于创建AV瘘管的血管潜力的方法，用于确定血管直径的方法，以及用于定位位于所述表面下方的血管的方法 的纸巾。