公开(公告)号：US20070106287A1

公开(公告)日：2007-05-10

申请号：US11236278

申请日：2005-09-26

申请人： Martin O'Sullivan

发明人： Martin O'Sullivan

IPC分类号： A61B18/18 ,  A61N1/00 ,  A61B5/05

CPC分类号： A61N1/04 ,  A61B18/1206 ,  A61B18/1492 ,  A61B34/20 ,  A61B2018/00351 ,  A61B2018/00779 ,  A61B2018/00839 ,  A61B2018/00869 ,  A61B2018/00875 ,  A61B2034/2051 ,  A61B2090/061 ,  A61N1/00 ,  A61N1/0517

摘要： A system and method for determining on a continuous, real-time basis the proximity of the esophagus to an endocardial catheter during mapping, ablation or other endocardial catheter-based procedures, comprising an esophagus probe catheter and an endocardial catheter adapted for proximal signal transmission between each other. A signal processing unit is included to process and compare a characteristic of the proximity signal that is changes or attenuates with distance between the two catheters, such as impedance, amplitude and/or phase. Audio and/or optical outputs are provided to alert an operator when the distance between the catheters changes or is below a baseline measurement to avoid damage to the esophagus by the endocardial catheter. The system and method may include adaptations of the catheters with location sensor, and a mapping/navigational system for nonfluoroscopic location determination of the catheters.

摘要翻译： 一种系统和方法，用于在映射，消融或其它基于心内膜导管的过程期间连续地实时地确定食管与心内膜导管的接近度，包括食管探针导管和心内膜导管，其适于在 彼此。 包括信号处理单元以处理和比较随着两个导管之间的距离（例如阻抗，幅度和/或相位）而改变或衰减的接近信号的特性。 提供音频和/或光学输出以在导管之间的距离改变或低于基线测量时提醒操作者，以避免心内膜导管损伤食道。 该系统和方法可以包括导管与位置传感器的适应，以及用于导管的非氟化位置确定的映射/导航系统。

公开(公告)号：US07118590B1

公开(公告)日：2006-10-10

申请号：US09914375

申请日：2000-02-25

申请人： Nigel Cronin

发明人： Nigel Cronin

IPC分类号： A61N1/06

CPC分类号： A61B18/14 ,  A61B18/1492 ,  A61B18/18 ,  A61B18/1815 ,  A61B2018/00577 ,  A61B2018/1861 ,  A61N1/04 ,  A61N5/04

摘要： Radiation applicators comprise an elongate device having an antenna (240, 340) at their tip for coupling radiation into biological tissue and a dielectric body (250, 350) surrounding the antenna so as to encompass substantially the whole of the near-field region of the antenna and/or to enhance transmission of radiation in the forward direction. The body (250, 350) may be cylindrical with the antenna (240, 340) along its axis. The antenna may be λ/2 in length and λ/2 in radius. The tip (270) of the antenna (240) may be rounded hemispherical with radius λ/2 to enhance forward transmission of radiation. The dielectric constant (ε) of the body (250, 350) is as high as possible to reduce its diameter at a desired operating frequency but may be matched to the surrounding tissue by another layer of dielectric material (380) with a value (ε) intermediate that of the core (360) of the body (350) and the tissue.

摘要翻译： 辐射施加器包括细长装置，其在其尖端处具有用于将辐射耦合到生物组织中的天线（240,340）和围绕天线的电介质体（250,350），以便覆盖基本上整个的近场区域 天线和/或增强向前方向的辐射透射。 主体（250,350）可以是沿其轴线的天线（240,340）的圆柱形。 天线可以是λ/ 2的长度和λ/ 2的半径。 天线（240）的尖端（270）可以是半径为λ/ 2的圆半球，以增强辐射的向前传输。 主体（250,350）的介电常数（ε）尽可能高以在期望的工作频率下减小其直径，但可以通过另一层介电材料（380）与周围组织匹配，其值（ε ）中间体（350）的核心（360）和组织。

公开(公告)号：US20060041301A1

公开(公告)日：2006-02-23

申请号：US10922297

申请日：2004-08-19

申请人： R. Ferrari

发明人： R. Ferrari

IPC分类号： A61N1/04

CPC分类号： A61B5/0408 ,  A61B2562/125 ,  A61B2562/17 ,  A61N1/04

摘要： A transcutaneous electrode is disclosed having a sheet electrode of an electrically-conductive material with an electrically conductive layer affixed to a major portion of the lower surface thereof. A pad of electrically-conductive gel is applied to the lower surface of the sheet electrode over the electrically-conductive layer. An electrical conductor having an unsheathed end portion is secured to the upper surface of the sheet electrode by an electrically-conductive adhesive. A high dielectric cover overlays the end out portion of the electrical conductor, and is secured to the sheet electrode by the conductive adhesive. A method for making the electrode is also disclosed.

摘要翻译： 公开了一种经皮电极，其具有导电材料的片状电极，导电层固定在其下表面的主要部分。 在导电层上的片状电极的下表面上涂敷导电性凝胶垫。 具有未固化端部的电导体通过导电粘合剂固定到片状电极的上表面。 高电介质盖覆盖电导体的端部，并通过导电粘合剂固定到片状电极上。 还公开了制造电极的方法。

公开(公告)号：US20050080407A1

公开(公告)日：2005-04-14

申请号：US10919612

申请日：2004-08-17

申请人： Chris Ehr ,  Joe Sartor

发明人： Chris Ehr ,  Joe Sartor

IPC分类号： A61B17/00 ,  A61B18/00 ,  A61B18/14 ,  A61B18/16 ,  A61N1/04 ,  H01R4/04 ,  H01R4/26 ,  H01R11/22 ,  H01R13/62

CPC分类号： A61N1/04 ,  A61B18/14 ,  A61B18/16 ,  A61B2017/00477 ,  A61B2018/00178 ,  A61B2018/00988 ,  H01R4/04 ,  H01R4/26 ,  H01R11/22 ,  H01R13/6205 ,  H01R2201/12 ,  Y10S128/908 ,  Y10S439/909

摘要： A return pad cable connector, in accordance with the present disclosure, for use with a disposable return pad, includes a cord having a conductive wire disposed therethrough which conductive wire interconnects the return pad cable connector to an electrosurgical energy source. The return pad clamp further includes a connector operatively coupled to the cord, the connector having a conductive surface which is selectively engageable with a corresponding conductive surface disposed on the return pad, the conductive surface of the connector including a conductive adhesive disposed thereon and a non-conductive adhesive disposed above the periphery of the conductive surface of the connector for engagement with a corresponding non-conductive adhesive disposed above the periphery of the conductive surface of the return pad. The connector can include a magnet for magnetically coupling the connector to the conductive surface disposed on the return pad.

摘要翻译： 根据本公开，用于与一次性返回垫一起使用的返回焊盘电缆连接器包括具有穿过其中布置的导线的导线，该导线将返回焊盘电缆连接器互连到电外科能源。 返回垫夹具还包括可操作地连接到绳索的连接器，该连接器具有导电表面，导电表面可选择性地与布置在返回垫上的对应的导电表面接合，连接器的导电表面包括设置在其上的导电粘合剂， 导电粘合剂，其设置在连接器的导电表面的周边之上，用于与设置在返回焊盘的导电表面的周边上方的相应的非导电粘合剂接合。 连接器可以包括用于将连接器磁耦合到设置在返回垫上的导电表面的磁体。

公开(公告)号：US06796828B2

公开(公告)日：2004-09-28

申请号：US10369896

申请日：2003-02-20

申请人： Chris J. Ehr ,  Joe D. Sartor

发明人： Chris J. Ehr ,  Joe D. Sartor

IPC分类号： H01R1362

CPC分类号： A61N1/04 ,  A61B18/14 ,  A61B18/16 ,  A61B2017/00477 ,  A61B2018/00178 ,  A61B2018/00988 ,  H01R4/04 ,  H01R4/26 ,  H01R11/22 ,  H01R13/6205 ,  H01R2201/12 ,  Y10S128/908 ,  Y10S439/909

摘要： A return pad cable connector, in accordance with the present disclosure, for use with a disposable return pad, includes a cord having a conductive wire disposed therethrough which conductive wire interconnects the return pad cable connector to an electrosurgical energy source. The return pad clamp further includes a connector operatively coupled to the cord, the connector having a conductive surface which is selectively engageable with a corresponding conductive surface disposed on the return pad, the conductive surface of the connector including a conductive adhesive disposed thereon and a non-conductive adhesive disposed above the periphery of the conductive surface of the connector for engagement with a corresponding non-conductive adhesive disposed above the periphery of the conductive surface of the return pad. The connector can include a magnet for magnetically coupling the connector to the conductive surface disposed on the return pad.

摘要翻译： 根据本公开，用于与一次性返回垫一起使用的返回焊盘电缆连接器包括具有穿过其中布置的导线的导线，该导线将返回焊盘电缆连接器互连到电外科能源。 返回垫夹具还包括可操作地连接到绳索的连接器，该连接器具有导电表面，导电表面可选择性地与布置在返回垫上的对应的导电表面接合，连接器的导电表面包括设置在其上的导电粘合剂， 导电粘合剂，其设置在连接器的导电表面的周边之上，用于与设置在返回焊盘的导电表面的周边上方的相应的非导电粘合剂接合。 连接器可以包括用于将连接器磁耦合到设置在返回垫上的导电表面的磁体。

公开(公告)号：US20040054393A1

公开(公告)日：2004-03-18

申请号：US10030483

申请日：2002-05-22

发明人： Goran Stemme ,  Jan Peter Enoksson ,  Patrick Griss ,  Pekka Merilainen

IPC分类号： A61N001/04

CPC分类号： A61B5/685 ,  A61B5/04025 ,  A61B5/0408 ,  A61B2562/0215 ,  A61N1/04

摘要： A medical electrode for obtaining biopotentials from the skin of a subject or electrically stimulating the subject's skin and deeper tissue layers. The electrode has a carrier base member from which project a plurality of spikes arranged in an array on one surface of the base member. The spikes are sufficiently long to penetrate through the stratum corneum into the stratum germinativum of the subject's skin. The spikes may be formed by a deep reactive ion etching process on a silicon wafer forming the base member. A fluid container may be formed on another surface of the skin for providing a drug to the surface of the skin through holes in the base member. The action of the spikes on the skin enhances administration of the drug.

摘要翻译： 一种用于从受试者的皮肤获得生物电位或电刺激受试者的皮肤和较深的组织层的医用电极。 电极具有载体基底构件，在基底构件的一个表面上突出有多个尖峰布置在阵列中。 尖峰足够长以穿透角质层进入受试者皮肤的生发层。 尖峰可以通过在形成基底构件的硅晶片上的深反应离子蚀刻工艺形成。 流体容器可以形成在皮肤的另一表面上，用于通过基底构件中的孔将药物提供给皮肤表面。 尖刺对皮肤的作用增强了药物的施用。

公开(公告)号：US06643541B2

公开(公告)日：2003-11-04

申请号：US10008720

申请日：2001-12-07

申请人： Swee Mok ,  Di-An Hong ,  Thomas S. Babin ,  Sanjar Ghaem

发明人： Swee Mok ,  Di-An Hong ,  Thomas S. Babin ,  Sanjar Ghaem

IPC分类号： A61B50488

CPC分类号： A61N1/08 ,  A61B5/0002 ,  A61B5/0488 ,  A61B2560/0271 ,  A61B2560/0412 ,  A61N1/04 ,  Y10S128/903

摘要： A wireless biopotential sensor includes an adhesive strip having a lower surface for placement against the skin of a patient and an upper surface. A pair of conductive electrodes are applied to the lower surface of the adhesive strip. A sensor substrate is applied to the upper surface. The sensor substrate includes first and second conductive contact pads that are placed in registry with the pair of conductive electrodes, with the contact pads arranged in electrical contact with the conductive electrodes. An electronics module is applied to the sensor substrate and arranged in electrical contact with the contact pads. The electronics module comprises a power supply and electronics for generating a wireless signal containing biopotential signals detected by the pair of conductive electrodes.

公开(公告)号：US06622035B1

公开(公告)日：2003-09-16

申请号：US09489556

申请日：2000-01-21

申请人： Pekka Merilainen ,  Heli Tolvanen-Laakso

发明人： Pekka Merilainen ,  Heli Tolvanen-Laakso

IPC分类号： A61B50408

CPC分类号： A61B5/685 ,  A61B5/04025 ,  A61B5/0408 ,  A61N1/04

摘要： An electrode for acquiring bioelectrical signals employs an array of spikes that penetrate the viable epidermis layer of the skin of a patient. The spikes may be conductive to provide the bioelectrical signal. Or, the spikes may extend through a conductive layer that provides the bioelectrical signal. The signal obtained from the patient may be amplified using an amplifier and battery circuit present on the electrode body. The electrode may be used with or without conductive paste or gel.

摘要翻译： 用于获取生物电信号的电极采用穿透患者皮肤的活的表皮层的尖峰阵列。 尖峰可能是导电的以提供生物电信号。 或者，尖峰可以延伸通过提供生物电信号的导电层。 可以使用存在于电极体上的放大器和电池电路来放大从患者获得的信号。 电极可以使用或不使用导电糊或凝胶。

公开(公告)号：US06360119B1

公开(公告)日：2002-03-19

申请号：US09739574

申请日：2000-12-18

申请人： Lauri E. Roberts

发明人： Lauri E. Roberts

IPC分类号： A61N104

CPC分类号： A61B5/04085 ,  A61B5/411 ,  A61B5/6833 ,  A61N1/04

摘要： Disclosed is an electrode placement with a series of electrodes disposed therein to be used for a one-step placement of electrodes. The device is shaped to allow it to be positioned and placed on a patient so that accurate placement of electrodes is achieved.

摘要翻译： 公开了一种电极布置，其中设置有一系列电极以用于电极的一步放置。 该装置成形为允许将其定位并放置在患者身上，从而实现电极的准确放置。

公开(公告)号：US6132752A

公开(公告)日：2000-10-17

申请号：US921471

申请日：1997-09-02

申请人： Christopher J. Pickett ,  Saad K. Ibrahim

发明人： Christopher J. Pickett ,  Saad K. Ibrahim

IPC分类号： A61K9/00 ,  A61N1/04 ,  A61N1/30 ,  C25B11/04 ,  G01N27/333 ,  A61F2/02 ,  A61F13/02

CPC分类号： A61N1/0436 ,  A61K9/0009 ,  A61N1/0428 ,  A61N1/04

摘要： This invention relates to modified electrodes their manufacture and use, to electro-release systems including such electrodes for electro-release of compounds, for example medical or veterinary pharmaceutical compounds, and to methods for electro-release. By electro-release is meant that the electrochemical release of the compound, or the inhibition of such release, is caused by the application of an appropriate voltage bias to an electrode. Such a system allows accurate control of timing and/or amount of release.

摘要翻译： 本发明涉及其制造和使用的电动释放系统，其包括用于化合物的电释放的电极，例如医用或兽用药物化合物，以及电释放方法。 通过电释放是指化合物的电化学释放或这种释放的抑制是通过向电极施加适当的电压偏压引起的。 这样的系统允许精确控制定时和/或释放量。