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公开(公告)号：US10399109B2
公开(公告)日：2019-09-03
申请号：US15476461
申请日：2017-03-31
Applicant: Stamford Devices Limited
Inventor： Brendan Hogan , Kieran Hyland , Anthony Redmond
Abstract: An aerosol generator (100) has a vibratable plate (1) with apertures therein and an annular piezo (2) which causes movement of the vibratable plate (1). An annular support member (3) supports the piezo (2) and the vibratable plate (1). A first electrical power conducting pin (10) engages directly with a first, top, surface of the piezo (2). A second electrical power conducting pin (11) indirectly conducts electrical power to a second surface of the piezo (2), by contacting an extension tab (103) of the support member (20), also on its top side. There is a film of cured epoxy adhesive on the tab (103), providing excellent gripping force between the pin (11) and the support (3). The aerosol generator (100) avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the on the same lateral and top side of the piezo and support member. The pins may have multi-point tips (50) for particularly effective electrical contact.
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公开(公告)号：US20190210044A1
公开(公告)日：2019-07-11
申请号：US16358338
申请日：2019-03-19
Applicant: Stamford Devices Limited
Inventor： Brendan Hogan , Hong Xu
CPC classification number: B05B1/02 , A61M11/005 , A61M15/0085 , A61M2207/00 , B05B17/0638 , B05B17/0653 , C25D1/08 , C25D7/04
Abstract: An aperture plate is manufactured by plating metal around a mask of resist columns having a desired size, pitch, and profile, which yields a wafer about 60 μm thickness. This is approximately the full desired target aperture plate thickness. The plating is continued so that the metal overlies the top surfaces of the columns until the desired apertures are achieved. This needs only one masking/plating cycle to achieve the desired plate thickness. Also, the plate has passageways formed beneath the apertures, formed as an integral part of the method, by mask material removal. These are suitable for entrainment of aerosolized droplets exiting the apertures.
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公开(公告)号：US20180369509A1
公开(公告)日：2018-12-27
申请号：US16118668
申请日：2018-08-31
Applicant: Stamford Devices Limited
Inventor： Patrick Joseph POWER , Jimmy EATON-EVANS
Abstract: A system for delivery of aerosol therapy to spontaneously breathing patients comprises a housing which defines a chamber. The housing has a base, a top and a main body extending between the base and the top. An ambient air inlet is located adjacent to the base and is normally closed by an inlet valve. The housing also has a patient port for receiving a mouthpiece or a face mask. The mouthpiece has an exhaust outlet closed by an exhaust valve. Similarly, the face mask has an exhaust outlet closed by an exhaust valve. Exhaled air is exhausted through the valves and to prevent recirculation through the chamber which would adversely affect dose efficiencies. The housing also has an aerosol port for receiving a vibrating mesh aerosol generating device. The aerosol port is located in a side of the main body of the housing for delivery of aerosol into the chamber between the inlet valve and the patient port. A boss extends upwardly from the base and is spaced-apart inwardly of the main body of the housing to define a reception space or well.
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公开(公告)号：US09956356B2
公开(公告)日：2018-05-01
申请号：US14423046
申请日：2014-05-23
Applicant: Stamford Devices Limited
Inventor： Joseph Grehan , Niall Smith
IPC: A61M11/00 , B05B17/06 , G01N29/22 , G01N29/42 , G06F19/00 , B05B17/00 , B06B1/02 , B05B12/00 , B05B12/08
CPC classification number: A61M11/005 , A61M11/001 , A61M2205/33 , A61M2205/3317 , B05B12/004 , B05B12/081 , B05B15/14 , B05B17/0646 , B05B17/0669 , B06B1/0253 , G01N29/22 , G01N29/42 , G06F19/00 , G06F19/3456 , G16H20/13
Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.
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公开(公告)号：US20170182279A1
公开(公告)日：2017-06-29
申请号：US15398059
申请日：2017-01-04
Applicant: Stamford Devices Limited
Inventor： John Sylvester Power , James B. Fink , Conor Paul Duffy , Trevor Stephen Fahy
Abstract: A supplemental oxygen delivery system is described in which Aerosol is delivered into a housing 10, 20, which sits in the circuit from the supplemental oxygen supply and optional humidifier. The supplemental oxygen passes through this chamber 10, 20 in which the aerosol is located, and collects the aerosol transporting it to a patient via a nasal cannula 3 or a face mask 4. An aerosol generator 9 is mounted to the housing 10, 20 and delivers aerosol into an oxygen stream 13 flowing between an inlet 14 and an outlet 15 of the housing 10. The housing 10 also has a removable plug 16 in the base 17 thereof for draining any liquid that accumulates in the housing 10. There is no disruption of oxygen delivery to patients using nasal cannulas who currently have to use a separate face-mask when receiving nebulized medication.
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Patent Agency Ranking
公开(公告)号：US20160167078A1
公开(公告)日：2016-06-16
申请号：US15048358
申请日：2016-02-19
Applicant: Stamford Devices Limited
Inventor： Brendan HOGAN , Kieran HYLAND , Anthony REDMOND
CPC classification number: B05B17/0646 , A61M11/001 , A61M11/005 , A61M15/0085
Abstract: An aerosol generator (100) has a vibratable plate (1) with apertures therein and an annular piezo (2) which causes movement of the vibratable plate (1). An annular support member (3) supports the piezo (2) and the vibratable plate (1). A first electrical power conducting pin (10) engages directly with a first, top, surface of the piezo (2). A second electrical power conducting pin (11) indirectly conducts electrical power to a second surface of the piezo (2), by contacting an extension tab (103) of the support member (20), also on its top side. There is a film of cured epoxy adhesive on the tab (103), providing excellent gripping force between the pin (11) and the support (3). The aerosol generator (100) avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the on the same lateral and top side of the piezo and support member. The pins may have multi-point tips (50) for particularly effective electrical contact.
Abstract translation: 气溶胶发生器（100）具有其中具有孔的可振动板（1）和引起可振动板（1）移动的环形压电体（2）。 环形支撑构件（3）支撑压电体（2）和可振动板（1）。 第一电力导电销（10）与压电体（2）的第一顶表面直接接合。 第二电力导电销（11）通过在支撑构件（20）的顶侧上接触支撑构件（20）的延伸片（103）来间接地将电力传导到压电体（2）的第二表面。 在片（103）上存在固化的环氧树脂粘合剂膜，在销（11）和支撑（3）之间提供优异的夹持力。 气溶胶发生器（100）避免了用于电接触的焊接接头的需要，并且销被方便地平行地安装在压电和支撑构件的同一横向和顶侧上。 引脚可以具有用于特别有效的电接触的多点尖端（50）。
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公开(公告)号：US09289792B2
公开(公告)日：2016-03-22
申请号：US13251924
申请日：2011-10-03
Applicant: Brendan Hogan , Kieran Hyland , Anthony Redmond
Inventor： Brendan Hogan , Kieran Hyland , Anthony Redmond
CPC classification number: B05B17/0646 , A61M11/001 , A61M11/005 , A61M15/0085
Abstract: An aerosol generator has a vibratable plate with apertures therein and an annular piezo which causes movement of the vibratable plate. An annular support member supports the piezo and the vibratable plate. A first electrical power conducting pin engages directly with a first, top, surface of the piezo. A second electrical power conducting pin indirectly conducts electrical power to a second surface of the piezo, by contacting an extension tab of the support member, also on its top side. There is a film of cured epoxy adhesive on the tab, providing excellent gripping force between the pin and the support. The aerosol generator avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the on the same lateral and top side of the piezo and support member. The pins may have multi-point tips for particularly effective electrical contact.
Abstract translation: 气溶胶发生器具有其中具有孔的可振动板和引起可振动板的移动的环形压电体。 环形支撑构件支撑压电体和可振动板。 第一电力导电销直接与压电体的第一顶部表面接合。 第二电力导电销通过在其顶侧上接触支撑构件的延伸片而间接地将电力传导到压电体的第二表面。 在接片上有一层固化的环氧树脂粘合剂，在销和支撑之间提供优异的夹持力。 气溶胶发生器避免了用于电接触的焊接接头的需要，并且销被方便地平行地安装在压电和支撑构件的同一横向和顶侧上。 引脚可以具有用于特别有效的电接触的多点尖端。
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公开(公告)号：US20130334338A1
公开(公告)日：2013-12-19
申请号：US13902096
申请日：2013-05-24
Applicant: Stamford Devices Limited
Inventor： Brendan Hogan
CPC classification number: A61M11/003 , A61M11/005 , B05B17/0646 , C25D1/08 , C25D3/567 , C25D7/00
Abstract: A photo-resist (21) is applied in a pattern of vertical columns having the dimensions of holes or pores of the aperture plate to be produced. This mask pattern provides the apertures which define the aerosol particle size, having up to 2500 holes per square mm. There is electro-deposition of metal (22) into the spaces around the columns (21). There is further application of a second photo-resist mask (25) of much larger (wider and taller) columns, encompassing the area of a number of first columns (2)1. The hole diameter in the second plating layer is chosen according to a desired flow rate.
Abstract translation: 光刻胶（21）以要制造的孔板的孔或孔的尺寸的垂直列的图案施加。 该掩模图形提供限定气溶胶颗粒尺寸的孔，每平方毫米具有多达2500个孔。 将金属（22）电沉积到柱（21）周围的空间中。 进一步应用包含多个第一列（2）1的区域的更大（更宽和更高）的列的第二光致抗蚀剂掩模（25）。 根据期望的流速选择第二镀层中的孔直径。
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公开(公告)号：US20130186975A1
公开(公告)日：2013-07-25
申请号：US13720759
申请日：2012-12-19
Applicant: Stamford Devices Limited
Inventor： Brendan Hogan , Daniela Butan , Seamus Clifford , Michael Pomeroy , Mark Southern , David Shiel
IPC: B05B17/06
CPC classification number: B05B17/0646 , B05B15/18 , B05B17/06 , B05B17/0653 , B05B17/0669
Abstract: An aperture plate is formed from a palladium nickel alloy comprising about 89% palladium and about 11% nickel. There is a generally fine substantially equiaxed grain microstructure throughout the thickness of the aperture plate. The average grain width (W) is in the range of from 0.2 μm to 5.0 μm, in some cases from 0.2 μm to 2.0 μm. Because the grain structure is equiaxed (L/W=1) the grain length (L) is the same as the grain width. The improved aperture plate extends the life of nebulisers, eliminates the risk of premature and unpredictable failure of a nebuliser in service, eliminates the risk of product returns from hospitals and patients, and eliminates the possible risk of fragments of the aperture plate breaking free from the nebulizer.
Abstract translation: 孔板由包含约89％钯和约11％镍的钯镍合金形成。 在孔板的整个厚度上存在通常细的基本上等轴晶粒微观结构。 平均晶粒宽度（W）在0.2μm至5.0μm的范围内，在一些情况下为0.2μm至2.0μm。 由于晶粒结构为等轴（L / W = 1），晶粒长度（L）与晶粒宽度相同。 改进的孔板延长了雾化器的寿命，消除了雾化器在使用过程中过早和不可预测的故障的风险，消除了医院和患者的产品返回风险，并消除了孔板破碎的可能性， 喷雾器。
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公开(公告)号：US12138382B2
公开(公告)日：2024-11-12
申请号：US17371412
申请日：2021-07-09
Applicant: Stamford Devices Limited
Inventor： John Power , Ronan MacLoughlin , Michael Casey , Conor Duffy , Aidan Duffy
IPC: A61M11/04 , A61M11/00 , A61M15/00 , B67D7/02 , G07F7/06 , G07F13/02 , G07F17/00 , G16H20/13 , G16H40/63
Abstract: A dispensing apparatus is for use by users to take a chamber, fill the chamber with an aerosolized vaccine or other medicament, and dispose of used chambers. A display provides instructions to encourage prompt inhalation by the user from a dispensed and filled chamber. The apparatus allows very fast administration of vaccines to large numbers of people. The aerosol dispenser apparatus detects the chamber is in correct position and delivers a pre-determined dose of aerosol. Once the dose is delivered a visual and/or audible indicator informs the user that the chamber is filled and that they can take the inhalation. The single dose aerosol chamber is optimized for efficient administration of an aerosol.
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