利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

2159 条记录 (耗时 0.041 秒)

    Methods of Treating, Ameliorating, Shortening Duration, and/or Reversing Symptoms and/or Complications of a Coronavirus Infection
    52.
    发明公开
    Methods of Treating, Ameliorating, Shortening Duration, and/or Reversing Symptoms and/or Complications of a Coronavirus Infection 审中-公开

    公开(公告)号：US20230226005A1

    公开(公告)日：2023-07-20

    申请号：US18002477

    申请日：2021-06-29

    申请人： Yale University

    发明人： Joseph M. Vinetz

    IPC分类号： A61K31/245 ,  A61P31/14

    CPC分类号： A61K31/245 ,  A61P31/14

    摘要： The present disclosure relates, in part, to methods of treating, ameliorating, shortening duration, and/or reversing at least one symptom and/or complication in a human subject with a coronavirus infection with camostat, or a pharmaceutically acceptable salt or solvate thereof. The present disclosure further relates to a method of preventing and/or reducing the occurrence of long COVID, and/or a symptom and/or complication thereof, hospitalization, and/or death in a human subject with a SARS-CoV-2 infection with camostat, or a pharmaceutically acceptable salt or solvate thereof. In certain embodiments, the camostat salt is camostat mesylate.

    COMPOSITIONS AND METHODS FOR TREATING LUNG INJURIES ASSOCIATED WITH VIRAL INFECTIONS
    57.
    发明公开
    COMPOSITIONS AND METHODS FOR TREATING LUNG INJURIES ASSOCIATED WITH VIRAL INFECTIONS 审中-公开

    公开(公告)号：US20230181582A1

    公开(公告)日：2023-06-15

    申请号：US17926104

    申请日：2021-05-20

    申请人： Qx Therapeutics Inc.

    发明人： Dianqing Wu ,  Ho Yin Lo

    IPC分类号： A61K31/506 ,  A61K31/496 ,  A61K45/06 ,  A61P31/14 ,  A61P11/00

    CPC分类号： A61K31/506 ,  A61K31/496 ,  A61K45/06 ,  A61P31/14 ,  A61P11/00

    摘要： The present invention provides methods and compositions for treating and preventing lung injuries due to or associated with viral infections, such as those due to coronaviruses that cause Severe Acute Respiratory Syndrome, including COVID-19. More specifically the present invention provides methods for treating or preventing the lung injuries often associated with these infections, such as acute lung injury (ALI), lung fibrosis, and acute respiratory distress syndrome (ARDS). The methods comprise administering a therapeutically effective amount of a pharmaceutical composition comprising a protein kinase inhibitor compound having MAP3K2/AP3K3 inhibition activity, such as pazopanib or nintedanib, or a pharmaceutically acceptable salt, solvate, or prodrug thereof, to a patient in need thereof, The present invention also provides devices for administering the compositions.