公开(公告)号：US20090161110A1

公开(公告)日：2009-06-25

申请号：US12048238

申请日：2008-03-14

Applicant: CHII-WANN LIN ,  NAN-FU CHIU ,  WEI-YI FENG ,  CHIA-CHEN CHANG ,  KUO-CHUAN HO ,  CHIH-KUNG LEE ,  KUANG-CHONG WU

Inventor： CHII-WANN LIN ,  NAN-FU CHIU ,  WEI-YI FENG ,  CHIA-CHEN CHANG ,  KUO-CHUAN HO ,  CHIH-KUNG LEE ,  KUANG-CHONG WU

IPC: G01N21/55

CPC classification number: G01N21/553

Abstract: Surface plasmon resonance (SPR) sensing technique which provides high specificity and accuracy has been an important method for molecular sensing technology. In the past, in order to affix 45 nm gold film onto glass or silicon substrate, several nanometers of chromium (Cr) or titanium (Ti) has been used as adhesive layer for the attachment of Au film. However, the existence of Cr or Ti thin film deteriorates the performance of SPR sensor due to their characteristic optical absorption. Our experimental results have confirmed the uses of conducting metal oxide, specifically, ITO and Zinc Oxide (ZnO) can be used to replace Cr or Ti for better performance in terms of SPR resonant properties (resonant angle and HMBW) and sensitivity enhancement for 3 to 15 times than traditional ones. It would contribute significantly to the SPR applications in both biosensors and gas sensors.

Abstract translation: 提供高特异性和准确度的表面等离子体共振（SPR）感测技术已成为分子感测技术的重要方法。 在过去，为了将45nm金膜贴在玻璃或硅衬底上，已经使用几纳米的铬（Cr）或钛（Ti）作为用于附着Au膜的粘合剂层。 然而，Cr或Ti薄膜的存在由于其特征性光吸收而使SPR传感器的性能劣化。 我们的实验结果证实了导电金属氧化物的用途，特别是ITO和氧化锌（ZnO）可以用于替代Cr或Ti，以获得更好的SPR谐振特性（谐振角和HMBW）性能，灵敏度提高为3〜 比传统的15倍。 这将有助于生物传感器和气体传感器中的SPR应用。

公开(公告)号：US20090073420A1

公开(公告)日：2009-03-19

申请号：US12076203

申请日：2008-03-14

Applicant: Chii-Wann Lin ,  Jheng-Long Lee ,  Rong-Huay Juang ,  Shi-Ming Lin ,  Chih-Kung Lee ,  Rea-Min Chu ,  Ching-Ho Wang ,  Jim-Min Fang ,  Tsung-Liang Chuang

Inventor： Chii-Wann Lin ,  Jheng-Long Lee ,  Rong-Huay Juang ,  Shi-Ming Lin ,  Chih-Kung Lee ,  Rea-Min Chu ,  Ching-Ho Wang ,  Jim-Min Fang ,  Tsung-Liang Chuang

IPC: G01N21/00

CPC classification number: G01N21/553

Abstract: An optical waveguide SPR sensor is adapted for differential measurement. The optical waveguide SPR sensor includes a base, a bottom layer, and at least one set of optical waveguide layers. The set of the optical waveguide layers includes a measuring optical waveguide channel and a reference optical waveguide channel. The measuring optical waveguide channel includes an SPR sensing film layer. The measuring optical waveguide channel and the reference optical waveguide channel are independently configured and substantially parallel one to another. The bottom layer has a refractive index higher than a refractive index of the optical waveguide layer.

Abstract translation: 光波导SPR传感器适用于差分测量。 光波导SPR传感器包括基底，底层以及至少一组光波导层。 该组光波导层包括测量光波导通道和参考光波导通道。 测量光波导通道包括SPR感测膜层。 测量光波导通道和参考光波导通道独立地构造并基本上彼此平行。 底层的折射率高于光波导层的折射率。

公开(公告)号：US20090015840A1

公开(公告)日：2009-01-15

申请号：US11849573

申请日：2007-09-04

Applicant: Chii-Wann Lin ,  Chih-Kung Lee ,  Tz-Bin Wang ,  Chi-Shen Tuan ,  Yueh-Yuan Fang

Inventor： Chii-Wann Lin ,  Chih-Kung Lee ,  Tz-Bin Wang ,  Chi-Shen Tuan ,  Yueh-Yuan Fang

IPC: G01N21/55

CPC classification number: G01N21/553

Abstract: The present invention provides a miniature surface plasmon resonance sensor chip that produces a plane light source with an organic optoelectronic material by an electro-luminescence method and excites a surface plasmon resonance wave to observe a signal variation at the surface of a sensor chip caused by the combining condition of surface bio-molecules and provide a more accurate miniature sensor in conformity with micro-channel.

Abstract translation: 本发明提供一种微型表面等离子体共振传感器芯片，其通过电致发光法产生具有有机光电子材料的平面光源，并且激发表面等离子体共振波，以观察由传感器芯片的表面引起的信号变化 结合表面生物分子的条件，并提供符合微通道的更精确的微型传感器。

公开(公告)号：US20070229836A1

公开(公告)日：2007-10-04

申请号：US11278638

申请日：2006-04-04

Applicant: Chii-Wann Lin ,  Nan-Fu Chiu ,  Jiun-Haw Lee ,  Lung-Jieh Yang ,  Yao-Joe Yang ,  Chih-Kung Lee

Inventor： Chii-Wann Lin ,  Nan-Fu Chiu ,  Jiun-Haw Lee ,  Lung-Jieh Yang ,  Yao-Joe Yang ,  Chih-Kung Lee

IPC: G01N21/55

CPC classification number: G01N21/553 ,  G01N21/554 ,  G01N2201/0628

Abstract: One embodiment of the present invention is a sensor for analyzing an analyte that includes: (a) an sensing element that is adapted to interface with the analyte; (b) an organic luminescent element that is adapted to excite surface plasmon resonance on the sensing element; and (c) a detector that is adapted to detect signals from the sensing element.

Abstract translation: 本发明的一个实施例是用于分析分析物的传感器，其包括：（a）适于与分析物相接触的感测元件; （b）适于在感测元件上激发表面等离子体共振的有机发光元件; 和（c）适于检测来自感测元件的信号的检测器。

公开(公告)号：US20070152539A1

公开(公告)日：2007-07-05

申请号：US11619909

申请日：2007-01-04

Applicant: Yao-Tien Huang ,  Wen-Hsin Hsiao ,  Yen-Chieh Wang ,  Yu-Yuan Chen ,  Wen-Jong Wu ,  Chih-Kung Lee

Inventor： Yao-Tien Huang ,  Wen-Hsin Hsiao ,  Yen-Chieh Wang ,  Yu-Yuan Chen ,  Wen-Jong Wu ,  Chih-Kung Lee

IPC: H01L41/107

CPC classification number: H01L41/107 ,  H01L41/044 ,  H05B41/2827

Abstract: In the present invention, a dual-output piezoelectric transformer for driving at least two loads is provided. The dual-output piezoelectric transformer comprises a piezoelectric piece, a set of input electrodes mounted centrally on a first and a second sides of the piece with a first polarization direction along a thickness direction of the piece, and a first and a second output electrodes polarized reversely in a second polarization direction and respectively mounted around surfaces of two ends of the piece with the second polarization direction being a longitudinal direction of the piece.

Abstract translation: 在本发明中，提供了用于驱动至少两个负载的双输出压电变压器。 双输出压电变压器包括压电片，一组输入电极，沿着该片的厚度方向以第一偏振方向居中安装在片的第一和第二侧上，第一和第二输出电极极化 相反地​​在第二偏振方向上并且分别安装在片的两端的表面上，其中第二偏振方向是片的纵向方向。

公开(公告)号：US07197196B2

公开(公告)日：2007-03-27

申请号：US10994777

申请日：2004-11-22

Applicant: Chii-Wann Lin ,  Cheng-Lung Lee ,  Way-Seen Wang ,  Chih Kung Lee

Inventor： Chii-Wann Lin ,  Cheng-Lung Lee ,  Way-Seen Wang ,  Chih Kung Lee

IPC: G02B6/26 ,  G01N21/55

CPC classification number: G01N21/553

Abstract: The present invention is in related to a miniature surface plasmon resonance waveguide device with sinusoidal curvature compensation and at least comprises: a substract, a waveguide structure, a sensing film layer and a cover layer, wherein the waveguide structure is configured with the function of sinusoidal curvature compensation and installed above the substract, further that, the waveguide structure includes a light input port and a light output port; the sensing film layer is on a special region of the waveguide structure, the special region is a sensing region; the cover layer is upper than the substract and has an opening. By means of the optimal curve figure of the sinusoidal curvature compensation, attenuation of light energy can be minimized while in propagation, and allows the input and output of the light on the same side of the device.

Abstract translation: 本发明涉及具有正弦曲率补偿的微型表面等离子体共振波导装置，并且至少包括：减法器，波导结构，感测膜层和覆盖层，其中波导结构被配置为具有正弦曲线 曲率补偿并安装在减法器上方，此外，波导结构包括光输入端口和光输出端口; 感光膜层位于波导结构的特殊区域，特殊区域为感应区域; 覆盖层高于该底部并且具有开口。 通过正弦曲率补偿的最佳曲线图，在传播过程中光能的衰减可以最小化，并允许光在设备同一侧的输入和输出。

公开(公告)号：US20060219307A1

公开(公告)日：2006-10-05

申请号：US11095075

申请日：2005-03-31

Applicant: An-Bang Wang ,  Zdenek Travnicek ,  Chun-Hsien Lee ,  Yi-Hua Wang ,  Ming-Chang Hsu ,  Chih-Kung Lee ,  Alexander Fedorchenko

Inventor： An-Bang Wang ,  Zdenek Travnicek ,  Chun-Hsien Lee ,  Yi-Hua Wang ,  Ming-Chang Hsu ,  Chih-Kung Lee ,  Alexander Fedorchenko

IPC: F15C1/20

CPC classification number: B01F13/0059 ,  B01F5/0256 ,  B01F11/0071 ,  B01F11/0074 ,  B01F13/0066 ,  B01F13/0072 ,  Y10T137/2174

Abstract: A micromixer used for microfluidic system is provided. The micromixer incorporates a pairs of reciprocating pumps and a pairs of fluidic element for mixing at least two fluids. With such a microfluid mixer, the at least two fluids are mixed when the reciprocating pumps are in their forward strokes by means of the impingement of two pulsation flows. The two fluids are also mixed when the reciprocating pumps are in their backward strokes by means of the generation of the vortexes, and the two fluids are also mixed by means of mass diffusion via a purposeful like-lamella-structure.

Abstract translation: 提供了用于微流体系统的微混合器。 微型混合器包括一对往复泵和一对流体元件，用于混合至少两种流体。 利用这样的微流体混合器，当往复泵通过两个脉动流的冲击而使往复泵处于其前冲程时，混合至少两种流体。 当往复泵通过产生涡流而往复泵处于向后冲程时，两种流体也混合，并且两种流体也通过有目的的类似薄片结构通过质量扩散混合。

公开(公告)号：US07071597B2

公开(公告)日：2006-07-04

申请号：US11155743

申请日：2005-06-16

Applicant: Chih-Kung Lee ,  Yu-Hsiang Hsu ,  Long-Sun Huang ,  Der-Chang Hsieh

Inventor： Chih-Kung Lee ,  Yu-Hsiang Hsu ,  Long-Sun Huang ,  Der-Chang Hsieh

IPC: H01L41/08

CPC classification number: H01L41/1132

Abstract: A motion sensing system utilizing piezoelectric laminates with predetermined surface electrode patterns disposed thereon utilizes a frequency selector to pass motion waves of predetermined frequencies and an electrical circuit for processing the electrical signals for transmission to an activating device for appropriate activation. In particular, the frequency selector is a low frequency bandpass filter for free-fall acceleration wave frequencies. By directing appropriate action, the present invention increases the applicability of the device upon which it is mounted (e.g., for military or other hostile environment use), decreases the possibility of damage, and lengthens its useful life.

公开(公告)号：US20050248236A1

公开(公告)日：2005-11-10

申请号：US11155743

申请日：2005-06-16

Applicant: Chih-Kung Lee ,  Yu-Hsiang Hsu ,  Long-Sun Huang ,  Der-Chang Hsieh

Inventor： Chih-Kung Lee ,  Yu-Hsiang Hsu ,  Long-Sun Huang ,  Der-Chang Hsieh

IPC: H01L41/08 ,  H01L41/113

CPC classification number: H01L41/1132

Abstract: A motion sensing system utilizing piezoelectric laminates with predetermined surface electrode patterns disposed thereon utilizes a frequency selector to pass motion waves of predetermined frequencies and an electrical circuit for processing the electrical signals for transmission to an activating device for appropriate activation. In particular, the frequency selector is a low frequency bandpass filter for free-fall acceleration wave frequencies. By directing appropriate action, the present invention increases the applicability of the device upon which it is mounted (e.g., for military or other hostile environment use), decreases the possibility of damage, and lengthens its useful life.

Abstract translation: 使用其上布置有预定表面电极图案的压电层压板的运动感测系统利用频率选择器来传递预定频率的运动波，以及用于处理电信号以用于传输到激活装置以进行适当激活的电路。 特别地，频率选择器是用于自由落体加速度波频率的低频带通滤波器。 通过引导适当的动作，本发明增加了安装在其上的装置的适用性（例如，对于军事或其他敌对环境使用），降低了损坏的可能性并延长其使用寿命。

公开(公告)号：US6115126A

公开(公告)日：2000-09-05

申请号：US235874

申请日：1999-01-22

Applicant: Yi-Chun Chen ,  Shu-Sheng Lee ,  Chung-Min Lee ,  Ching-Wei Chen ,  Heui-Yung Chang ,  Gym-Bin Yeh ,  Chih-Kung Lee ,  Shih-Tsong Lin ,  Chi-Tang Hsieh ,  Wei-Liang Chen

Inventor： Yi-Chun Chen ,  Shu-Sheng Lee ,  Chung-Min Lee ,  Ching-Wei Chen ,  Heui-Yung Chang ,  Gym-Bin Yeh ,  Chih-Kung Lee ,  Shih-Tsong Lin ,  Chi-Tang Hsieh ,  Wei-Liang Chen

IPC: G01J9/02 ,  G01B9/02

CPC classification number: G01J9/0215

Abstract: An optical wavefront analyzer based on the phase-shearing interferometry technique for measuring a wavefront of a light beam is disclosed. The analyzer includes a single phase shifter, a driving device, a pattern receiving device, and a phase reconstructing device. A method of measuring a wavefront of a light beam is also provided for solving the problems of two-axial focusing and phase inconsistency encountered the prior art by employing phase-shearing and phase-shifting techniques to improve the method of optical wavefront mesurement. A non-iterative, path-independent unwrapping methodology is used to deal with a complicated wavefront.

Abstract translation: 公开了一种基于用于测量光束的波前的相位剪切干涉技术的光学波前分析器。 该分析器包括单个移相器，驱动装置，模式接收装置和相位重建装置。 还提供了一种测量光束的波前的方法，用于通过采用相位剪切和相移技术来改进光波前测量的方法来解决现有技术中遇到的双轴向聚焦和相位不一致的问题。 非迭代的路径独立展开方法用于处理复杂的波前。