Abstract:
An aortic arch device that is a unitary tube of graft material having a crimped unstented portion and a stented portion, a collar at the junction of the crimped unstented portion and the stented portion, at least one fenestration or lateral opening in the graft material to accommodate arteries in the aortic arch. Branches may extend from the fenestrations.
Abstract:
Various stents and stent-graft systems for treatment of medical conditions are disclosed. In one embodiment, an exemplary stent-graft system may be used for endovascular treatment of a thoracic aortic aneurysm. The stent-graft system may comprise proximal and distal components, each comprising a graft having proximal and distal ends, where upon deployment the proximal and distal components at least partially overlap with one another to provide a fluid passageway therebetween. The proximal component may comprise a proximal stent having a plurality of proximal and distal apices connected by a plurality of generally straight portions, where a radius of curvature of at least one of the proximal apices may be greater than the radius of curvature of at least one of the distal apices. The distal component may comprise a proximal z-stent coupled to the graft, where the proximal end of the graft comprises at least scallop formed therein that generally follows the shape of the proximal z-stent. Further, the distal component may comprise at least one z-stent stent coupled to the distal end of the graft and extending distally therefrom that reduces proximal migration of the distal component.
Abstract:
An introducer assembly includes an introducer element (80), which may have a catheter or sheath (82), a pusher element (84) holding an implantable medical device (88) and a dilator tip (90). The assembly also includes a protective sleeve (72) within which the introducer element (80) is disposed. The protective sleeve (72) is made of an absorbable hydrophilic material which is deployed in a wetted condition and acts as a cushion or barrier between the introducer element (80) and the vessel wall (60). The sleeve can prevent trauma to the vessel during the deployment of the introducer element (80) and as a result can avoid vessel spasm which can occur in delicate vessels such as the cerebral vessels. The introducer assembly may be used for cerebral applications.
Abstract:
An implantable medical device includes a support structure which is twistable in a longitudinal direction of the device. A sleeve of filter or occluding material is attached to the ends of the structure. The structure in practice twists on itself in the longitudinal direction, causing the sleeve to twist on itself and as a result to close the lumen through the sleeve. The device provides reliable closure and as a result occlusion of a vessel. It is also able to be delivered over a guide wire. In another embodiment, the support structure includes a wire which coils around the sleeve to constrict the sleeve and as a result to close a lumen of the sleeve.
Abstract:
A handle assembly for a delivery device the sequential release of trigger wires from a prosthesis to release the prosthesis from the delivery device. The handle assembly has two handles, one of which is a rotating handle. The rotating handle has a first and second trigger wire release mechanisms which operate to sequentially release a first and second trigger wire, respectively, and a locking mechanism. The other handle has a locking mechanism that prevents that operation of the second trigger wire release mechanism until the first trigger wire has been released.
Abstract:
A vascular closure device includes a frame to which there is fitted a plurality of anchor elements, spaced radially around the frame. The closure device includes a radial compression feature, which may be a memorised shape of the frame or non-sprung condition of the frame, having a small radius. The closure device is deployed in a vessel such that the anchor elements are embedded into the vessel wall. The radial compression feature causes the frame to compress radially, as a result of which the anchor elements will pull the vessel wall inwardly, thereby closing the vessel.
Abstract:
A vascular closure device includes a frame to which there is fitted a plurality of anchor elements, spaced radially around the frame. The closure device includes a radial compression feature, which may be a memorized shape of the frame or non-sprung condition of the frame, having a small radius. The closure device is deployed in a vessel such that the anchor elements are embedded into the vessel wall. The radial compression feature causes the frame to compress radially, as a result of which the anchor elements will pull the vessel wall inwardly, thereby closing the vessel.
Abstract:
A pre-loaded stent graft delivery device and stent graft, the stent graft delivery device. The stent graft has at least one fenestration or side arm and the fenestration is preloaded with an indwelling guide wire. Indwelling access sheaths are provided within auxiliary lumens of a pusher catheter and dilators are preloaded into the access sheaths along with the indwelling guide wire. A handle assembly at a distal end of the guide wire catheter. The handle includes a multiport manifold with access ports to the auxiliary lumens in the pusher catheter. Upon deployment of the stent graft into the vasculature of a patient, the indwelling guide wire can be used to facilitate cathertisation of a side branch or target vessel through the fenestration or be used to stabilise the access sheath during catheterisation, advancement of the access sheath into the target vessel and deployment of a covered or uncovered stent therein through the access sheath.
Abstract:
A system for deploying a stent graft includes a stent graft. The stent graft has a tubular structure and includes first and second end stents and at least one stent between the first and second end stents. The system also includes a plurality of constraining mechanisms arranged along the length of the stent graft constraining the stents of the stent graft, and an actuation mechanism configured to release the plurality of constraining mechanisms in order from the first end to the second end of the stent graft and circumferentially sequentially from about the stents.
Abstract:
A stent graft delivery device that is pre-loaded with a single guide wire for both tracking the device within a main vessel as well as for cannulating one or more branch vessels is described. The delivery device comprises a delivery catheter having a prosthesis releasably secured thereto and a nose cone extending from the proximal end of the catheter. In a delivery configuration, a secondary catheter is coaxial with the guide wire and extends through at least a portion of the prosthesis lumen and is held within a channel formed in the nose cone. In a released configuration, secondary catheter and guide wire are retracted distally out of the channel formed in the sidewall of the nose cone dilator and can be manipulated for cannulating a branch vessel.