利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

204 条记录 (耗时 0.049 秒)

    Methods and apparatus for predicting acute response to cardiac resyncronization therapy at a given stimulation site
    52.
    发明授权
    Methods and apparatus for predicting acute response to cardiac resyncronization therapy at a given stimulation site 有权
    用于预测给定刺激部位心脏再同步化治疗的急性反应的方法和装置

    公开(公告)号：US08639334B2

    公开(公告)日：2014-01-28

    申请号：US11562681

    申请日：2006-11-22

    申请人： Julio Spinelli ,  Yinghong Yu

    发明人： Julio Spinelli ,  Yinghong Yu

    IPC分类号： A61B5/04

    CPC分类号： A61N1/365 ,  A61N1/3627 ,  A61N1/368 ,  A61N1/3682

    摘要： Response to cardiac resynchronization therapy is predicted for a given stimulation site so that an atrioventricular delay of an implantable device administering cardiac resynchronization therapy may be set to a proper amount. The first deflection of ventricular depolarization is measured, such as through a surface electrocardiogram or through an intracardiac electrogram measured by a lead positioned in the heart at the stimulation site. The maximum deflection of the ventricular depolarization is then measured by the lead positioned at the stimulation site. The interval of time between the first deflection and the maximum deflection of the ventricular depolarization is compared to a threshold to determine whether the stimulation site is a responder site. If the interval is larger than the threshold, then the site is a responder and the atrioventricular delay of the implantable device may be set to less than the intrinsic atrioventricular delay of the patient. Otherwise, the atrioventricular may be set to approximately equal the intrinsic atrioventricular delay.

    摘要翻译： 对于给定的刺激部位预测对心脏再同步治疗的响应，使得施用心脏再同步治疗的可植入装置的房室延迟可以被设定为适当的量。 测量心室去极化的第一偏转，例如通过表面心电图或通过位于刺激部位心脏中的导线测量的心内电描记图。 然后通过位于刺激部位的引线测量心室去极化的最大偏转。 将心室去极化的第一偏转和最大偏转之间的时间间隔与阈值进行比较以确定刺激位点是否是应答位点。 如果间隔大于阈值，则该位点是响应者，并且可植入装置的房室延迟可被设置为小于患者的内在房室延迟。 否则，房室可以设定为近似等于内在房室延迟。

    Cardiac activation sequence monitoring for ischemia detection
    53.
    发明授权
    Cardiac activation sequence monitoring for ischemia detection 失效
    心脏激活序列监测缺血检测

    公开(公告)号：US08626276B2

    公开(公告)日：2014-01-07

    申请号：US12847657

    申请日：2010-07-30

    申请人： Yi Zhang ,  Scott A. Meyer ,  Jeffrey E. Stahmann ,  Carlos Alberto Ricci ,  Marina Brockway ,  Aaron R. McCabe ,  Yinghong Yu ,  Donald L. Hopper

    发明人： Yi Zhang ,  Scott A. Meyer ,  Jeffrey E. Stahmann ,  Carlos Alberto Ricci ,  Marina Brockway ,  Aaron R. McCabe ,  Yinghong Yu ,  Donald L. Hopper

    IPC分类号： A61B5/04

    CPC分类号： A61N1/3702 ,  A61B5/0452 ,  A61B5/7203

    摘要： Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed to detect, monitor, track and/or trend ischemia using cardiac activation sequence information. Ischemia detection may involve sensing composite cardiac signals using implantable electrodes, and performing a signal separation that produces one or more cardiac activation signal vectors associated with one or more cardiac activation sequences. A change in the signal vector may be detected using subsequent separations. The change may be an elevation or depression of the ST segment of a cardiac cycle or other change indicative of myocardial ischemia, myocardial infarction, or other pathological change. The change may be used to predict, quantify, and/or qualify an event such as an arrhythmia, a myocardial infarction, or other pathologic change. Information associated with the vectors may be stored and used to track the vectors.

    摘要翻译： 提供一种或多种监测，诊断，除颤和起搏的心脏监测和/或刺激方法和系统。 使用心脏信号分离来使用心脏激活序列信息来检测，监测，跟踪和/或趋势性缺血。 缺血检测可以涉及使用可植入电极感测复合心脏信号，并且执行产生与一个或多个心脏激活序列相关联的一个或多个心脏激活信号载体的信号分离。 可以使用后续分离来检测信号矢量的变化。 该变化可以是心​​脏周期的ST段的升高或抑制或指示心肌缺血，心肌梗死或其他病理变化的其它变化。 该变化可用于预测，量化和/或限定诸如心律失常，心肌梗死或其它病理变化的事件。 与矢量相关联的信息可以被存储并用于跟踪矢量。

    OPTIMIZATION OF LV AND RV LEAD PLACEMENT BASED ON ELECTRICAL DELAYS
    56.
    发明申请
    OPTIMIZATION OF LV AND RV LEAD PLACEMENT BASED ON ELECTRICAL DELAYS 有权
    基于电延迟优化LV和RV导线放置

    公开(公告)号：US20130190636A1

    公开(公告)日：2013-07-25

    申请号：US13552996

    申请日：2012-07-19

    申请人： Shibaji Shome ,  Pramodsingh Hirasingh Thakur ,  Yinghong Yu ,  Keith L. Herrmann ,  Aaron R. McCabe ,  Jiang Ding

    发明人： Shibaji Shome ,  Pramodsingh Hirasingh Thakur ,  Yinghong Yu ,  Keith L. Herrmann ,  Aaron R. McCabe ,  Jiang Ding

    IPC分类号： A61B5/0456 ,  A61B5/04

    CPC分类号： A61B5/0456 ,  A61B5/04012 ,  A61N1/3684 ,  A61N1/3686 ,  A61N1/3702 ,  A61N1/37247 ,  A61N1/3918

    摘要： A system comprises a cardiac signal sensing and a processing circuit. The cardiac signal sensing circuit senses a first cardiac signal segment that includes a QRS complex and a second cardiac signal segment that includes a fiducial indicative of local ventricular activation. The processor circuit includes a site activation timer circuit configured to determine a time duration between a fiducial of the QRS complex of the first cardiac signal segment and the fiducial of the second cardiac signal segment. The processor circuit is configured to generate, using the determined time duration, an indication of optimality of placement of one or more electrodes for delivering therapy and provide the indication to at least one of a user or process.

    摘要翻译： 一种系统包括心脏信号感测和处理电路。 心脏信号感测电路感测包括QRS复合物的第一心脏信号片段和包括指示局部心室激活的基准的第二心脏信号片段。 处理器电路包括站点激活定时器电路，其被配置为确定第一心脏信号段的QRS复合体的基准点与第二心脏信号段的基准点之间的持续时间。 处理器电路被配置为使用所确定的持续时间来生成用于递送治疗的一个或多个电极的放置的最佳化的指示，并向至少一个用户或过程提供指示。

    AV delay features
    57.
    发明授权
    AV delay features 有权
    AV延迟功能

    公开(公告)号：US08483825B2

    公开(公告)日：2013-07-09

    申请号：US12336064

    申请日：2008-12-16

    申请人： Yinghong Yu ,  Jiang Ding

    发明人： Yinghong Yu ,  Jiang Ding

    IPC分类号： A61N1/00

    CPC分类号： A61N1/368 ,  A61B5/0452 ,  A61N1/3627 ,  A61N1/3682 ,  A61N1/3684

    摘要： At least one of a left intraventricular conduction defect, a right intraventricular conduction defect, or no intraventricular conduction defect can be detected using received intrinsic cardiac information from a subject, and a first atrioventricular (AV) delay can be calculated using a first relationship if the left intraventricular conduction defect or no intraventricular conduction defect is detected, or a second AV delay can be calculated using a second relationship if the right intraventricular conduction defect is detected.

    摘要翻译： 可以使用来自受试者的接收的固有心脏信息来检测左室内传导缺陷，右心室内传导缺陷或无心室内传导缺陷中的至少一个，并且可以使用第一关系来计算第一房室（AV）延迟，如果 如果检测到右心室传导缺陷，则检测到左心室内传导缺陷或无心室传导缺陷，或者可以使用第二关系计算第二AV延迟。

    GUIDEWIRE AND SIGNAL ANALYZER FOR PACING SITE OPTIMIZATION
    58.
    发明申请
    GUIDEWIRE AND SIGNAL ANALYZER FOR PACING SITE OPTIMIZATION 有权
    指南和信号分析仪用于PACING SITE OPTIMIZATION

    公开(公告)号：US20120130220A1

    公开(公告)日：2012-05-24

    申请号：US13293707

    申请日：2011-11-10

    申请人： Barun Maskara ,  Yinghong Yu ,  Bruce A. Tockman ,  Sunipa Saha ,  Martin McDaniel ,  Geng Zhang

    发明人： Barun Maskara ,  Yinghong Yu ,  Bruce A. Tockman ,  Sunipa Saha ,  Martin McDaniel ,  Geng Zhang

    IPC分类号： A61B5/042 ,  A61N1/36 ,  A61N1/39 ,  A61B19/00

    CPC分类号： A61N1/056 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/0472 ,  A61B5/6851 ,  A61N1/37241 ,  A61N2001/0585

    摘要： Cardiac lead implantation systems, devices, and methods for lead implantation are disclosed. An illustrative cardiac lead implantation system comprises a mapping guidewire including one or more electrodes configured for sensing cardiac electrical activity, a signal analyzer including an analysis module configured for analyzing an electrocardiogram signal sensed by the mapping guidewire, and a user interface configured for monitoring one or more hemodynamic parameters within the body. The sensed electrical activity signal can be used by the analysis module to compute a timing interval associated with ventricular depolarization.

    摘要翻译： 公开了用于引线植入的心脏引线植入系统，装置和方法。 示例性心脏引线植入系统包括：映射导丝，其包括被配置为感测心脏电活动的一个或多个电极;信号分析器，包括被配置用于分析由所述映射导丝所感测的心电图信号的分析模块;以及用户界面，被配置为监视一个或 更多血液动力学参数在体内。 感测的电活动信号可以被分析模块用于计算与心室去极化相关的定时间隔。

    Method and system for delivering cardiac resynchronization therapy with variable atrio-ventricular delay
    59.
    发明授权
    Method and system for delivering cardiac resynchronization therapy with variable atrio-ventricular delay 有权
    用心脏再同步治疗可变心房延迟的方法和系统

    公开(公告)号：US08121685B2

    公开(公告)日：2012-02-21

    申请号：US12622602

    申请日：2009-11-20

    申请人： Jiang Ding ,  Yinghong Yu ,  Milton M. Morris

    发明人： Jiang Ding ,  Yinghong Yu ,  Milton M. Morris

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36585 ,  A61N1/3627 ,  A61N1/3682 ,  A61N1/3684

    摘要： A pacing system computes optimal cardiac resynchronization pacing parameters using intrinsic conduction intervals. In various embodiments, values for atrio-ventricular delay intervals are each computed as a function of an intrinsic atrio-ventricular interval and a parameter reflective of an interventricular conduction delay. Examples of the parameter reflective of the interventricular conduction delay include QRS width and interval between right and left ventricular senses.

    摘要翻译： 起搏系统使用内在导电间隔计算最佳心脏再同步起搏参数。 在各种实施例中，心室间隔延迟间隔的值各自被计算为内在房室间隔和反映室间传导延迟的参数的函数。 反映室间传导延迟的参数的示例包括QRS宽度和右心室感觉和左心室感觉之间的间隔。

    Cardiac pacing using adjustable atrio-ventricular delays
    60.
    发明授权
    Cardiac pacing using adjustable atrio-ventricular delays 有权
    心脏起搏使用可调节的心房延迟

    公开(公告)号：US08103345B2

    公开(公告)日：2012-01-24

    申请号：US12955218

    申请日：2010-11-29

    申请人： Jiang Ding ,  Yinghong Yu ,  Andrew P. Kramer ,  Julio C. Spinelli

    发明人： Jiang Ding ,  Yinghong Yu ,  Andrew P. Kramer ,  Julio C. Spinelli

    IPC分类号： A61N1/365

    CPC分类号： E21B17/01 ,  A61N1/3627 ,  A61N1/3682 ,  E21B43/36

    摘要： A pacing system for providing optimal hemodynamic cardiac function for parameters such as contractility (peak left ventricle pressure change during systole or LV+dp/dt), or stroke volume (aortic pulse pressure) using system for calculating atrio-ventricular delays for optimal timing of a ventricular pacing pulse. The system providing an option for near optimal pacing of multiple hemodynamic parameters. The system deriving the proper timing using electrical or mechanical events having a predictable relationship with an optimal ventricular pacing timing signal.

    摘要翻译： 一种起搏系统，用于为诸如收缩性（收缩期峰值左心室压力变化或LV + dp / dt）之间的参数或行程体积（主动脉脉压）提供最佳血液动力学心脏功能，使用用于计算心室延迟的系统以获得最佳时机 心室起搏脉搏。 该系统为多个血液动力学参数的近似最佳起搏提供了选择。 该系统使用与最佳心室起搏定时信号具有可预测关系的电或机械事件导出适当的定时。