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    METHODS OF IDENTIFYING AND REPLACING IMPLANTED HEART VALVES
    51.
    发明申请
    METHODS OF IDENTIFYING AND REPLACING IMPLANTED HEART VALVES 有权
    识别和替换植入心脏瓣膜的方法

    公开(公告)号：US20170071735A1

    公开(公告)日：2017-03-16

    申请号：US15362472

    申请日：2016-11-28

    Applicant: Edwards Lifesciences Corporation

    Inventor： Jessica Guttenberg ,  Da-Yu Chang ,  Derrick Johnson ,  Brian S. Conklin ,  Qinggang Zeng ,  Myron Howanec, JR. ,  Grace Myong Kim

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2250/0085 ,  A61F2250/0089 ,  A61F2250/0098

    Abstract: A prosthetic heart valve configured to replace a native heart valve and for post-implant expansion and having a valve-type indicator thereon visible from outside the body post-implant. The indicator communicates information about the valve, such as the size or orifice diameter of the valve, and/or that the valve has the capacity for post-implant expansion. The indicator can be an alphanumeric symbol or other symbol or combination of symbols that represent information about the characteristics of the valve such as the valve size. The capacity for post-implant expansion facilitates a valve-in-valve procedure, where the valve-type indicator conveys information to the surgeon about whether the implanted valve is suitable for the procedure and informs the choice of the secondary valve.

    Abstract translation: 一种假体心脏瓣膜，其构造成代替天然心脏瓣膜并用于植入后扩张，并且在体外植入后可从外部观察到瓣膜型指示器。 指示器传达关于阀的信息，例如阀的尺寸或孔直径，和/或阀具有用于植入物扩张的能力。 指示符可以是代表关于阀的特性的信息的字母数字符号或其他符号或符号的组合，例如阀的尺寸。 植入后扩张的能力有利于瓣膜瓣膜手术，其中瓣膜型指示器向外科医生传达关于植入的瓣膜是否适于手术并且通知二次瓣膜的选择的信息。

    SYSTEMS FOR DEPLOYING KNOTLESS SUTURE ANCHORING CLAMPS
    52.
    发明申请
    SYSTEMS FOR DEPLOYING KNOTLESS SUTURE ANCHORING CLAMPS 有权
    用于配置无缝固定锚固系统的系统

    公开(公告)号：US20170071600A1

    公开(公告)日：2017-03-16

    申请号：US15362529

    申请日：2016-11-28

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Salvador Marquez ,  Donald E. Bobo, JR.

    IPC: A61B17/04 ,  A61F2/24

    CPC classification number: A61B17/0487 ,  A61B17/0401 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0416 ,  A61B2017/0464 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61F2/24 ,  A61F2/2409 ,  A61F2/2442

    Abstract: Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.

    Abstract translation: 用于固定假体（例如心脏瓣膜或带有缝线和瓣环的瓣环成形术环）的缝合线锁定件提高了植入的容易性。 夹具具有相对的夹具半部，该半部由通向一侧的狭槽分开，并被诸如一个或多个C形夹弹簧的偏置构件包围。 缝合线横向穿过狭槽，狭槽由位于夹子半部之间的保持构件保持打开。 锁定夹具沿着缝合线滑动到适当位置，调节缝合线的张力，并且移除保持构件以允许偏置构件将缝合线夹在夹具半部之间。 用于传送和展开锁定夹具的输送工具在堆叠中的输送管内包含多个夹具，并且为了安全而将其粘合在一起并具有公共保持构件。 该工具在一侧具有用于进入缝合线的纵向通道。

    METHODS OF DYNAMIC ANNULOPLASTY RING SIZING
    54.
    发明申请
    METHODS OF DYNAMIC ANNULOPLASTY RING SIZING 有权
    动态平均尺寸的方法

    公开(公告)号：US20160256278A1

    公开(公告)日：2016-09-08

    申请号：US15155863

    申请日：2016-05-16

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin

    IPC: A61F2/24 ,  A61B5/107

    CPC classification number: A61F2/2496 ,  A61B5/107 ,  A61B5/1076 ,  A61B5/6852 ,  A61B5/6869 ,  A61B90/06 ,  A61B2090/0807 ,  A61F2/2445 ,  A61F2/2472 ,  A61F2250/001 ,  A61F2250/0097

    Abstract: A dynamic, adjustable annuloplasty ring sizer can include an adjustable ring replica, which can be adjusted through a range of sizes corresponding to available prosthetic annuloplasty repair ring sizes. Actuation of an adjustment trigger on a handle portion of the ring sizer can displace tension wires that extend through a malleable shaft and through a plurality of articulating segments that form the ring replica. Displacement of the tension wires causes flexion of the joints between adjacent articulating segments, thereby reducing the overall size of the ring replica. Releasing the tension wires can allow an elastic extension wire to act on the ring replica, enlarging the ring replica to its maximum, at-rest size. In this manner, the appropriate size of annuloplasty ring prosthesis can be determined with a single device, without requiring a plurality of static ring sizers that require individual insertion and placement for the conventional trial-and-error sizing methods.

    Abstract translation: 动态，可调节瓣环成形术环形筛分器可以包括可调整的环形复制件，其可以通过对应于可用的假体瓣环成形术修复环尺寸的一系列尺寸进行调整。 在环形筛分机的手柄部分上的调节触发器的致动器可以移动延伸穿过可延展的轴并通过形成环形复制件的多个铰接段的张力线。 张力线的位移导致相邻铰接段之间的接头弯曲，从而减小环形复制体的总体尺寸。 释放张力线可以允许弹性延伸线作用在环形复制品上，将环形复制品放大到最大静止尺寸。 以这种方式，可以使用单个装置来确定瓣环成形术假体的适当尺寸，而不需要多个静态环形筛分器，其需要单独的插入和放置用于常规的试验和误差尺寸测量方法。

    METHODS OF ANCHORING CARDIAC IMPLANTS USING KNOTLESS SUTURE FASTENERS
    55.
    发明申请
    METHODS OF ANCHORING CARDIAC IMPLANTS USING KNOTLESS SUTURE FASTENERS 有权
    使用无关紧固件锚固心脏植入物的方法

    公开(公告)号：US20150320414A1

    公开(公告)日：2015-11-12

    申请号：US14797162

    申请日：2015-07-12

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Salvador Marquez

    IPC: A61B17/04 ,  A61F2/24

    CPC classification number: A61F2/2427 ,  A61B17/0401 ,  A61B17/0469 ,  A61B17/0483 ,  A61B17/0487 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61F2/2412 ,  A61F2/2466

    Abstract: Devices and methods for securing prostheses such as heart valves or annuloplasty rings with sutures and without using knots are disclosed. The devices are particularly well suited for traditional surgery or minimally invasive surgery, and improve the ease of implantation by eliminating surgical knots a clinician would normally tie in the limited space in and around the implant site. The devices have opposed the clamp halves surrounded by a coil spring. Sutures pass between the clamp halves and the coil spring has an inner coil diameter sufficient to compress the sutures between the clamp. A retention member positioned between the clamp halves maintains a minimum space and therebetween to enable the locking device to be slid along the sutures into position, and to adjust the tension of the sutures therethrough. A delivery tool may be used to deliver and deploy the locking devices.

    Abstract translation: 公开了用于固定假体的装置和方法，例如具有缝合线并且不使用结的心脏瓣膜或瓣环成形术环。 该装置特别适用于传统手术或微创手术，并通过消除手术结，提高植入的容易程度，临床医生通常会将植入部位内部和周围的有限空间结合在一起。 这些装置相对于由螺旋弹簧包围的夹子半部。 缝线穿过钳夹半部之间并且螺旋弹簧具有足以压缩夹具之间的缝合线的内线圈直径。 定位在夹钳半部之间的保持构件保持最小空间并且在其间，使得锁定装置能够沿着缝线滑动到位，并且通过其调节缝合线的张力。 传送工具可用于传送和部署锁定装置。

    PROSTHETIC HEART VALVE, SYSTEM, AND METHOD
    56.
    发明申请
    PROSTHETIC HEART VALVE, SYSTEM, AND METHOD 有权
    前置心脏瓣膜，系统和方法

    公开(公告)号：US20150230922A1

    公开(公告)日：2015-08-20

    申请号：US14663101

    申请日：2015-03-19

    Applicant: Edwards Lifesciences Corporation

    Inventor： Hengchu Cao ,  Brian S. Conklin ,  Paul A. Schmidt ,  Grace M. Kim ,  James A. Davidson ,  Hoa T. Tran ,  Kristy L. Tam

    IPC: A61F2/24

    CPC classification number: A61F2/2427 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2415

    Abstract: Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions. Examples of delivery systems and methods for deploying the valves exhibit reduced patient trauma.

    Abstract translation: 公开的假体瓣膜可以包括构造成将瓣膜固定到植入部位的缝合环。 一些公开的阀包括具有中性构型和折叠展开构型的弹性可折叠框架。 当从折叠部署配置释放时，一些公开的框架可以自扩展到中立配置。 折叠所公开的阀可以方便地进入缝合环，例如用于将瓣膜固定到植入部位，以及通过相对较小的手术切口插入瓣膜。 用于部署阀的递送系统和方法的示例表现出减少的患者创伤。

    ADJUSTABLE THREE-DIMENSIONAL ANNULOPLASTY RING
    60.
    发明公开
    ADJUSTABLE THREE-DIMENSIONAL ANNULOPLASTY RING 审中-公开

    公开(公告)号：US20230414355A1

    公开(公告)日：2023-12-28

    申请号：US18465094

    申请日：2023-09-11

    Applicant: EDWARDS LIFESCIENCES CORPORATION

    Inventor： Brian S. Conklin

    IPC: A61F2/24

    CPC classification number: A61F2/2448 ,  A61F2/2466 ,  A61F2220/0008 ,  A61F2250/0008 ,  A61F2250/0012 ,  A61F2250/0097 ,  A61F2230/0095

    Abstract: An annuloplasty ring for repair of mitral valves whose shape can be altered remotely to perform post-implant size and/or shape adjustments. On version of the annuloplasty ring has a size-adjustable remodeling inner core within an outer suture-permeable interface for attaching the ring to an annulus. The inner core has an arcuate anterior segment that overlaps an arcuate posterior segment on opposite sides, with the segments being shaped in three dimensions to conform to the mitral annulus. The overlapping sides may have a ratchet mechanism with teeth on one engaging a detent on the other, or mating undulating bumps that can be adjusted in increments. A pair of adjustment filaments that pass through a delivery system and through channels in one segment may act on the other segment to adjust the peripheral shape of the annuloplasty ring.

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