Multi-capillary array electrophoresis device
    53.
    发明授权
    Multi-capillary array electrophoresis device 有权
    多毛细管阵列电泳装置

    公开(公告)号:US07250098B2

    公开(公告)日:2007-07-31

    申请号:US10259492

    申请日:2002-09-30

    IPC分类号: G01N27/453

    CPC分类号: G01N27/44782 G01N27/44721

    摘要: An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than that of air and less than that of water and reduces the amount of laser beams scattered by the capillaries. Also provided are methods of adjusting refracted and reflected excitation light beams passing through capillaries of a multi-capillary array, to reduce loss of intensity of the laser beams and increase irradiation of respective samples disposed in the capillaries.

    摘要翻译: 电泳装置包括具有设置在阵列的毛细管之间的液体或固体的多毛细管阵列。 液体或固体的折射率高于空气的折射率,小于水的折射率,并减少了由毛细管散射的激光束的数量。 还提供了调节通过多毛细管阵列的毛细管的折射和反射的激发光束的方法,以减少激光束的强度损失并增加设置在毛细管中的各个样品的照射。

    Multi-capillary array electrophoresis device
    54.
    发明授权
    Multi-capillary array electrophoresis device 有权
    多毛细管阵列电泳装置

    公开(公告)号:US08043493B2

    公开(公告)日:2011-10-25

    申请号:US11714221

    申请日:2007-03-06

    IPC分类号: G01N27/453

    CPC分类号: G01N27/44782 G01N27/44721

    摘要: An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than that of air and less than that of water and reduces the amount of laser beams scattered by the capillaries. Also provided are methods of adjusting refracted and reflected excitation light beams passing through capillaries of a multi-capillary array, to reduce loss of intensity of the laser beams and increase irradiation of respective samples disposed in the capillaries.

    摘要翻译: 电泳装置包括具有设置在阵列的毛细管之间的液体或固体的多毛细管阵列。 液体或固体的折射率高于空气的折射率,小于水的折射率,并减少了由毛细管散射的激光束的数量。 还提供了调节通过多毛细管阵列的毛细管的折射和反射的激发光束的方法,以减少激光束的强度损失并增加设置在毛细管中的各个样品的照射。

    Analyzer
    56.
    发明授权
    Analyzer 有权
    分析仪

    公开(公告)号:US09393562B2

    公开(公告)日:2016-07-19

    申请号:US13983340

    申请日:2012-01-13

    摘要: Provided is an analyzer capable of reducing the amount of wasted reagents and shortening time required for solution sending, thus increasing throughput for analysis. A microsyringe sucks a minimum required amount of reagent that is substantially the same amount of capacity of a flow cell to a sampling nozzle. Then, the sampling nozzle is inserted into an injection port of the flow cell, and the reagent is injected into the flow cell by driving the microsyringe. The inside of the sampling nozzle is cleaned by moving the sampling nozzle to the cleaning tank and ejecting cleaning water from the sampling nozzle, and the outside of the sampling nozzle is cleaned by spraying cleaning water from an inner wall of the cleaning tank.

    摘要翻译: 提供了能够减少试剂浪费量和溶液发送所需时间缩短的分析装置,从而提高分析用量。 微量注射器将最小所需量的试剂吸收到与采样喷嘴相当的流动池的容量基本上相同的量。 然后,将取样喷嘴插入流通池的注入口,通过驱动微量注射器将试剂注入到流通池中。 通过将采样喷嘴移动到清洗槽并从采样喷嘴喷射清洗水来清洁采样喷嘴的内部,并且通过从清洗槽的内壁喷射清洁水来清洁采样喷嘴的外部。

    Capillary electrophoresis apparatus
    57.
    发明授权
    Capillary electrophoresis apparatus 有权
    毛细管电泳仪

    公开(公告)号:US08702949B2

    公开(公告)日:2014-04-22

    申请号:US13263040

    申请日:2010-04-08

    IPC分类号: G01N27/453

    CPC分类号: G01N27/44743 G01N27/44782

    摘要: The solution reservoir apparatus of the capillary electrophoresis apparatus securely affixes an evaporation-preventing membrane to a container when a capillary is inserted or withdrawn, without extending the cathode end of the capillary. The solution reservoir apparatus comprises a container for reserving a sample or solution, a cover having a bore through which the capillary is passed and covering the container, an evaporation-preventing membrane having a capillary hole through which the capillary is passed, and a container holder for holding the container. The evaporation-preventing membrane has a projection provided at the periphery of the capillary hole, the projection of the evaporation-preventing membrane is engaged with the bore on the cover when the evaporation-preventing membrane is positioned on the cover, and the evaporation-preventing membrane is supported by the cover.

    摘要翻译: 当毛细管插入或取出时,毛细管电泳装置的溶液储存装置在不延长毛细管的阴极端的情况下,将防蒸发膜牢固地固定在容器上。 溶液储存装置包括用于储存样品或溶液的容器,具有孔的盖,毛细管穿过孔覆盖容器,具有毛细孔通过的毛细孔的防蒸发膜和容器保持架 用于拿着容器。 防蒸发膜具有设置在毛细孔周边的突起,当防蒸发膜位于盖上时,防蒸发膜的突起与盖上的孔接合,并且防蒸发膜 膜由盖支撑。

    ELECTROPHORESIS DEVICE AND PUMP
    58.
    发明申请
    ELECTROPHORESIS DEVICE AND PUMP 有权
    电泳装置和泵

    公开(公告)号:US20120031762A1

    公开(公告)日:2012-02-09

    申请号:US13263304

    申请日:2010-04-06

    IPC分类号: F04B19/20 G01N27/00

    摘要: Bubbles can be removed regardless of an individual difference of a pump to fill an electrophoresis medium into a capillary. Of flow passages formed between an inner side surface of a container for accommodating the electrophoresis medium and a side surface of a plunger, one of the flow passages causing an electrophoresis medium to be easily stagnant is formed to have the cross-sectional area larger than the cross-sectional area of the other flow passage on the opposite side. In other words, the flow passage portion causing the electrophoresis medium to be easily stagnant is formed in such a manner as to increase a flow amount of the electrophoresis medium. This can eliminate a region having an extremely small amount of electrophoresis medium flow in the pump.

    摘要翻译: 不管泵的个体差异,将电泳介质填充到毛细管中,都可以去除气泡。 在容纳电泳介质的容器的内侧面和柱塞的侧面之间形成的流路之间形成有引起电泳介质容易停滞的流路之一,其横截面积大于 另一个流动通道的相对侧的横截面面积。 换句话说,导致电泳介质容易停滞的流通部分以增加电泳介质的流量的方式形成。 这可以消除在泵中具有极少量的电泳介质流动的区域。

    CAPILLARY ELECTROPHORESIS DEVICE
    59.
    发明申请
    CAPILLARY ELECTROPHORESIS DEVICE 有权
    毛细管电泳装置

    公开(公告)号:US20080296160A1

    公开(公告)日:2008-12-04

    申请号:US12130330

    申请日:2008-05-30

    IPC分类号: C07K1/26

    CPC分类号: G01N27/44704

    摘要: Provided is a capillary electrophoresis device including a holder preventing a septum from coming off when a capillary is pulled out, and also allowing containers to be taken out in any order. In the capillary electrophoresis device for separating and analyzing a sample such as a DNA and a protein by electrophoresis, the holder includes: a septum having a capillary hole through which a capillary penetrates; a container for storing a solution; and a container-accommodation unit for accommodating the container. A hole formed in the septum engages with an engagement portion formed on the container, and thereby the septum is held to cover the container.

    摘要翻译: 本发明提供一种毛细管电泳装置,其包括:当毛细管被拉出时防止隔膜脱落的保持器,并且还允许以任何顺序取出容器。 在用于通过电泳分离和分析诸如DNA和蛋白质的样品的毛细管电泳装置中,保持器包括:具有毛细管穿过的毛细孔的隔膜; 用于存储解决方案的容器; 以及用于容纳容器的容器收纳单元。 形成在隔膜上的孔与形成在容器上的接合部接合,从而保持隔膜以覆盖容器。