公开(公告)号：US11280740B2

公开(公告)日：2022-03-22

申请号：US16968330

申请日：2018-04-06

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Steven Barcelo ,  Anita Rogacs ,  Raghuvir N. Sengupta

IPC: G01N21/65 ,  G01J3/44 ,  G01N21/64 ,  G01N21/552 ,  B82Y15/00

Abstract: A luminescence-enhancement system can include a luminescence-enhancement sensor having a substrate and a group of nanofingers with individual nanofingers that can be flexible and include a support end attached to the substrate, a distal tip positioned distally with respect to the substrate, and a middle portion between the support end and the distal tip. A coating of a metal or metal alloy can be applied to the substrate and the distal tip that is conductively continuous. The middle portion can be devoid of the coating or the coating at the middle portion is conductively discontinuous. A liquid ejector can be present and can include a jetting nozzle to eject a liquid droplet having a volume of 2 pL to 10 μL. The group of nanofingers and the jetting nozzle can be positionable relative to one another for the droplet to be deposited on the group of nanofingers.

公开(公告)号：US11213791B2

公开(公告)日：2022-01-04

申请号：US15763064

申请日：2015-10-22

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Steven Barcelo ,  Ning Ge ,  Anita Rogacs

IPC: B01D63/00 ,  B01D69/10 ,  B01D39/16 ,  B01D61/38 ,  B01D63/08 ,  B01D67/00 ,  B01L3/00 ,  B01D69/04 ,  B01D69/14

Abstract: A microporous structure includes an array of nano wires and a coating about the nano wires of the array. The coating defines pores between the nano wires.

公开(公告)号：US11162901B2

公开(公告)日：2021-11-02

申请号：US16074298

申请日：2016-04-20

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Ning Ge ,  Anita Rogacs ,  Viktor Shkolnikov ,  Alexander Govyadinov

IPC: G01N21/65 ,  G01N21/03 ,  B82Y40/00 ,  B82Y15/00

Abstract: A surface enhanced Raman scattering (SERS) sensor may include a substrate, an electrically conductive layer having a first portion spaced from a second portion by a gap, an electrically resistive layer in contact with and extending between the first portion and the second portion of the electrically conductive layer to form an electrically resistive bridge across the gap that heats the nano fingers in response to electrical current flowing across the bridge from the first portion to the second portion and nano fingers extending upward from the bridge.

公开(公告)号：US20210222112A1

公开(公告)日：2021-07-22

申请号：US17256333

申请日：2018-10-09

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Fausto D'Apuzzo ,  Anita Rogacs

IPC: C12M1/34 ,  G02B1/06 ,  G02B21/00 ,  G02B21/36 ,  G06K9/00 ,  G02B1/00 ,  G02B21/06

Abstract: An example apparatus includes a sampling layer to position microscopic objects thereon, a light encoding layer to encode light from passing through the microscopic objects of the sampling layer, the light encoding layer having a substantially flat form, and an imaging layer to capture an image of the sampling layer, the image being encoded by the light encoding layer.

公开(公告)号：US11067513B2

公开(公告)日：2021-07-20

申请号：US16710819

申请日：2019-12-11

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Francesco Aieta ,  Anita Rogacs ,  Viktor Shkolnikov

IPC: G01N21/65 ,  G01J3/02 ,  G01J3/44 ,  G01J3/10 ,  G01J3/18

Abstract: In an example, an apparatus is described that includes a light source, a holographic optical element, a sampling apparatus, and a detector. The light source is configured to emit a beam of excitation light. The holographic optical element is arranged to convert the beam of excitation light into a plurality of beams of excitation light. The sampling apparatus is arranged to project the plurality of beams of excitation light onto a surface outside the apparatus as a two-dimensional pattern of projection points. The sampling apparatus is further arranged to collect scattered radiation emitted by the surface in response to the two-dimensional pattern of projection points. The detector detects a frequency shift in the scattered radiation.

公开(公告)号：US10983061B2

公开(公告)日：2021-04-20

申请号：US16606429

申请日：2017-10-24

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Steven Barcelo ,  Anita Rogacs ,  Raghuvir N. Sengupta

IPC: B82Y15/00 ,  G01N21/65

Abstract: A surface enhanced luminescence analyte nano pillar stage may include a substrate, an array of closable pillars extending from the substrate and a fluid supply connected to the array of pillars. The fluid supply is to at least partially replenish fluid amongst the pillars of the array that has evaporated to maintain a level of the fluid amongst the pillars of the array below tops of the pillars.

公开(公告)号：US10969339B2

公开(公告)日：2021-04-06

申请号：US16838662

申请日：2020-04-02

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Charles M. Santori ,  James William Stasiak ,  Francesco Aieta ,  Anita Rogacs ,  Mineo Yamakawa ,  Kenneth Ward

IPC: G01N21/65

Abstract: Optical readers are disclosed in examples herein. An example optical reader including a light source to emit a light beam; and a spot pattern generator to receive the light beam and to generate a two-dimensional spot array from the light beam, the two-dimensional spot array to be directed toward a substrate having nanostructures, the two-dimensional spot array to be sensed to detect a presence or an absence of a substance of interest on the substrate.

公开(公告)号：US10888866B2

公开(公告)日：2021-01-12

申请号：US15772511

申请日：2016-02-29

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Viktor Shkolnikov ,  Anita Rogacs

IPC: B01L3/00 ,  C12M1/00 ,  G01N21/03 ,  G01N21/11 ,  G01N21/65

Abstract: A liquid directing sample container includes a well. The well has sides and a floor. The sides having a non-circular profile having an interior angle that, at a target location within the well, is smaller than other interior angles of the profile to wick liquid towards the target location. The floor is sloped downward towards the target location.

公开(公告)号：US10830643B2

公开(公告)日：2020-11-10

申请号：US16592135

申请日：2019-10-03

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Francesco Aieta ,  Charles M. Santori ,  Anita Rogacs

IPC: G01J3/30 ,  G01N21/64 ,  G01N15/14 ,  G01J3/02 ,  G01J3/44 ,  G02B21/16 ,  G01J3/28 ,  G02B21/00 ,  G01N15/00 ,  G01N21/65 ,  G01N15/10

Abstract: In one implementation, a spectral microscope may comprise a substrate with a planar lens, the planar lens including a phase profile including an axial focus and an oblique focus, a light source to excite a signal of a particle among a plurality of particles, and a detector to receive light generated from the light source from the axial focus of the planar lens and a spectral color component of the excited signal of the particle from the oblique focus of the planar lens.

公开(公告)号：US10670459B2

公开(公告)日：2020-06-02

申请号：US15770466

申请日：2016-02-29

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Viktor Shkolnikov ,  Anita Rogacs

IPC: G01J3/44 ,  G01J3/02 ,  G01N21/65 ,  G01N35/04 ,  G01N21/11 ,  G01N35/00 ,  G01N21/25

Abstract: An apparatus includes a sample carrier having wells. Each of the wells has sides and a floor forming an interior. A surface enhanced Raman spectroscopy (SERS) structure is within the interior of each of the wells. A pneumatic port is connected to the interior of each of the wells. A pneumatic passage is connected to the pneumatic ports.