公开(公告)号：US20130057803A1

公开(公告)日：2013-03-07

申请号：US13697612

申请日：2011-04-25

申请人： Shigenori Tanaka

发明人： Shigenori Tanaka

IPC分类号： G02F1/13357 ,  F21V8/00

CPC分类号： G02F1/133615 ,  G02B6/0088 ,  G02F2001/133317

摘要： A liquid crystal module includes a planar light source device and a liquid crystal panel which are combined together by use of a double-sided adhesive tape (not illustrated). The double-sided adhesive tape is provided on a part of a resin frame, which part is on a light-exit-plane side. A part of the resin frame, which part is not provided with the double-sided adhesive tape, has an uneven surface or has a slit on a surface thereof. In other words, a part of the resin frame, which part corresponds to sections where the planar light source device and the liquid crystal panel are not combined together, has an uneven surface or has a slit on a surface thereof.

摘要翻译： 液晶模块包括通过使用双面胶带（未示出）组合在一起的平面光源装置和液晶面板。 双面胶带设置在树脂框架的一部分上，该部分在光出射面侧。 树脂框架的不具有双面胶带的部分具有不平坦表面或在其表面上具有狭缝。 换句话说，树脂框架的一部分对应于平面光源装置和液晶面板未组合在一起的部分，具有不平坦表面或在其表面上具有狭缝。

公开(公告)号：US20130038817A1

公开(公告)日：2013-02-14

申请号：US13642893

申请日：2011-02-23

申请人： Yoshinobu Hirayama ,  Shigenori Tanaka ,  Ryoh Araki

发明人： Yoshinobu Hirayama ,  Shigenori Tanaka ,  Ryoh Araki

IPC分类号： F21V8/00 ,  G02F1/13357

CPC分类号： F21S2/00 ,  G02B6/0045 ,  G02F1/133605

摘要： A liquid crystal display device (100) of the present invention includes an edge light type backlight unit (10) and a liquid crystal panel (20). The backlight unit (10) includes a light guide plate (2) and a light source (1) that emits light to a light entrance end surface (2a) of the light guide plate (2). An opposite end surface (2b), of the light guide plate (2), which is opposite to the light entrance end surface (2a), is shaped to have one or more triangular shape(s) or one or more rounded shape(s) in a cross section both in a thickness direction of the light guide plate (2) and in a peak luminance direction of light from the light source (1). Light parallel to the peak luminance direction, which light is from the light source (1), is suitably reflected without being scattered by an inclined surface of the opposite end surface (2b).

摘要翻译： 本发明的液晶显示装置（100）包括边缘光型背光单元（10）和液晶面板（20）。 背光单元（10）包括向导光板（2）的光入射端面（2a）发光的导光板（2）和光源（1）。 导光板（2）的与光入射端面（2a）相对的相对端面（2b）成形为具有一个或多个三角形形状或一个或多个圆形（s） ）在导光板（2）的厚度方向和来自光源（1）的光的峰值亮度方向的截面中。 平行于来自光源（1）的光的峰值亮度方向的光被适当地反射而不被相对端面（2b）的倾斜表面散射。

公开(公告)号：US06905558B2

公开(公告)日：2005-06-14

申请号：US10288377

申请日：2002-11-06

申请人： Shigenori Tanaka ,  Toyoichiro Higashi ,  Masahiro Doki ,  Jun Fukuda ,  Hiroshi Ohba ,  Mitsuo Uchimura

发明人： Shigenori Tanaka ,  Toyoichiro Higashi ,  Masahiro Doki ,  Jun Fukuda ,  Hiroshi Ohba ,  Mitsuo Uchimura

IPC分类号： B22D11/115 ,  B22D11/12 ,  C22C38/00 ,  B22D11/00 ,  B22D27/02

CPC分类号： B22D11/1206 ,  B22D11/115

摘要： A billet produced by continuous casting having little central segregation, in particular a billet of high carbon steel produced by continuous casting, and a manufacturing method therefor are provided. In the continuous casting billet, the size of the dendritic equiaxed crystal in a billet central portion is reduced to be not more than 6 mm. For this purpose, electromagnetic stirring is performed so that the inclining angle of the primary dendrite within 10 mm of a billet surface layer is increased to be not less than 10°. Furthermore, the mechanical soft reduction is performed during continuous casting so that the diameter of the center porosity in the billet central portion is reduced to be not more than 4 mm. Thereby, in particular in the manufacturing of the continuous casting billet having a carbon content of not less than 0.6% by mass and a billet size of not more than 160 mm can be provided a billet in which breaking troubles in wire drawing after rolling to a rod are reduced by reducing the central segregation in the billet.

摘要翻译： 通过连续铸造制造的具有很少中心偏析的坯料，特别是通过连续铸造生产的高碳钢坯料及其制造方法。 在连铸坯中，坯锭中心部分的树枝状等轴晶体的尺寸减小到不超过6mm。 为此，进行电磁搅拌，使得在钢坯表面层的10mm以内的一次枝晶的倾斜角度不小于10°。 此外，在连续铸造期间进行机械软还原，使得坯锭中心部分的中心孔隙的直径减小到不大于4mm。 因此，特别是在制造碳含量不小于0.6质量％，坯锭尺寸不大于160mm的连铸坯的情况下，可以提供轧制后的拉丝断裂的坯料 通过减少坯料的中心偏析来减少棒材。

公开(公告)号：US06511553B1

公开(公告)日：2003-01-28

申请号：US09403232

申请日：1999-10-15

申请人： Junji Nakashima ,  Takashi Sawai ,  Mitsuo Uchimura ,  Wataru Yamada ,  Shigenori Tanaka ,  Yasuharu Sakuma ,  Akinobu Murasato

发明人： Junji Nakashima ,  Takashi Sawai ,  Mitsuo Uchimura ,  Wataru Yamada ,  Shigenori Tanaka ,  Yasuharu Sakuma ,  Akinobu Murasato

IPC分类号： C22C3806

CPC分类号： C22C38/001 ,  C21C7/0006 ,  C21C7/06 ,  C22C38/04 ,  C22C38/14 ,  Y02P10/212

摘要： The present invention provides a steel for steel sheets excellent in workability and showing significantly decreased formation of surface defects, and a method of deoxidizing molten steel for the steel for steel sheets which prevents nozzle clogging during continuous-casting the molten steel. That is, the steel for steel sheets excellent in workability, comprises, based on weight, 0.0001 to 0.0030% of C, up to 0.03% of Si, 0.05 to 0.30% of Mn, up to 0.015% of P, 0.001 to 0.015% of S, up to 0.008% of Al, 0.02 to 0.08% of Ti, 0.0005 to 0.0020% of Ca, 0.0005 to 0.01% of N, optionally containing at least one of 0.001 to 0.02 wt % of Nb and 0.0001 to 0.0010 wt % of B, and the balance of Fe and unavoidable impurities. Moreover, the deoxidation method of the steel for steel sheets comprises properly adjusting addition amounts of Ca and Al as deoxidizing agents for the steel having the chemical composition mentioned above so that the chemical composition of the nonmetallic inclusions is controlled to prevent clogging of the casting nozzle.

摘要翻译： 本发明提供一种加工性优异，表面缺陷形成显着降低的钢板用钢，以及钢水连续铸造时防止喷嘴堵塞的钢板钢的脱氧方法。 也就是说，加工性优异的钢板用钢的重量为C：0.0001〜0.0030％，Si：0.03％以下，Mn：0.30〜0.30％，P：0.015％以下，0.001〜0.015％ 的S，至多0.008％的Al，0.02〜0.08％的Ti，0.0005〜0.0020％的Ca，0.0005〜0.01％的N，任选含有0.001〜0.02重量％的Nb和0.0001〜0.0010重量％的至少一种， 的B，余量为Fe和不可避免的杂质。 此外，钢板的钢的脱氧方法包括适当地调节Ca和Al的添加量作为具有上述化学组成的钢的脱氧剂，使得控制非金属夹杂物的化学组成以防止铸造喷嘴的堵塞 。

公开(公告)号：US06168924A

公开(公告)日：2001-01-02

申请号：US08954792

申请日：1997-10-21

申请人： Hiroshi Tamura ,  Shigenori Tanaka ,  Maki Watanabe

发明人： Hiroshi Tamura ,  Shigenori Tanaka ,  Maki Watanabe

IPC分类号： G01N3353

CPC分类号： G01N33/579 ,  Y10S436/825 ,  Y10T436/25125

摘要： The presence of endotoxin in the outer membrane of cell wall of a Gram-negative bacteria is used to determine bacterial contamination in a biological product. The amount of endotoxin present in a biological product is accurately measured without influence of a limulus reaction-activating substance which causes a false-positive reaction, by a method including the steps of: inactivating the limulus reaction-activating substance, if any, in the biological product, by exposing the biological product to a surfactant at a temperature ranging from the surfactant's freezing point to 50° C.; and measuring the amount of endotoxin present in the biological product, using a limulus reagent.

摘要翻译： 使用革兰氏阴性细菌细胞壁外膜内毒素的存在来确定生物制品中的细菌污染。 存在于生物制品中的内毒素的量在不影响引起假阳性反应的鲎反应活化物质的情况下被精确测量，方法包括以下步骤：使鲎反应活化物质（如果有的话）灭活 通过在表面活性剂的凝固点至50℃​​的温度下将生物产物暴露于表面活性剂中来生物制品。 并使用鲎试剂测量生物制品中存在的内毒素的量。

公开(公告)号：US5695948A

公开(公告)日：1997-12-09

申请号：US661705

申请日：1996-06-11

申请人： Shigenori Tanaka ,  Hiroshi Tamura ,  Kazuhiro Aita

发明人： Shigenori Tanaka ,  Hiroshi Tamura ,  Kazuhiro Aita

IPC分类号： G01N33/543 ,  G01N33/579 ,  C12Q1/56 ,  C12Q1/00 ,  C12Q1/34 ,  C12Q1/44

CPC分类号： G01N33/579 ,  G01N2333/811 ,  Y10S435/967

摘要： This invention provides (1) a reagent for endotoxin assay which comprises aprotinin and a limulus amebocyte lysate reagent, (2) a kit for endotoxin assay which comprises the limulus amebocyte lysate reagent and a reagent containing aprotinin, (3) a method for assaying endotoxin in a sample using the limulus amebocyte lysate reagent in which aprotinin is added to the lysate reagent and/or the sample, (4) a method for assaying endotoxin in a serine protease-containing sample using the limulus amebocyte lysate reagent in which the sample is allowed to contact with an aprotinin-immobilized insoluble carrier in advance of endotoxin assay, (5) a carrier for pretreating a serine protease-containing sample on which aprotinin is immobilized, (6) a method for inhibiting factor G activation in which aprotinin is added to the limulus amebocyte lysate reagent and (7) a factor G activation inhibitor which comprises aprotinin as an active ingredient. Endotoxin assay can be effected based on the factor C system reaction, without influences of factor G contained in the limulus amebocyte lysate reagent and/or serine proteases contained in samples.

摘要翻译： 本发明提供（1）含有抑肽酶和鲎变形细胞裂解物试剂的内毒素试剂，（2）包含鲎变形细胞裂解物试剂和含有抑肽酶的试剂的内毒素试剂盒，（3）检测内毒素的方法 在使用鲎变形细胞裂解物试剂的样品中，其中将抑肽酶加入到裂解物试剂和/或样品中，（4）使用鲎变形细胞裂解物试剂测定含丝氨酸蛋白酶样品中的内毒素的方法，其中样品是 在内毒素测定之前允许与抑肽酶固定的不溶性载体接触，（5）用于预处理含有抑肽酶的丝氨酸蛋白酶的样品的载体，（6）抑制因子G激活的方法，其中加入抑肽酶 到鲎变形细胞裂解物试剂和（7）包含抑肽酶作为活性成分的因子G激活抑制剂。 内毒素测定可以基于因子C系统反应进行，而不受样品中包含的鲎变形细胞裂解物试剂和/或丝氨酸蛋白酶中所含因子G的影响。

公开(公告)号：US5605806A

公开(公告)日：1997-02-25

申请号：US427260

申请日：1995-04-24

申请人： Shigenori Tanaka ,  Hiroshi Tamura

发明人： Shigenori Tanaka ,  Hiroshi Tamura

IPC分类号： G01N33/579 ,  G01N33/569 ,  G01N33/543

CPC分类号： G01N33/579 ,  Y10S435/962

摘要： The present invention provides a reagent for assaying an endotoxin which comprises limulus amoebocyte lysate and an antibody to (1 .fwdarw. 3)-.beta.-D-glucan sensitive factor or a reagent which comprises a lysate substantially free from (1 .fwdarw. 3)-.beta.-D-glucan sensitive factor. The reagent of the present invention makes it possible to assay an endotoxin originating from gram-negative bacteria contained in a biological sample such as blood, urine and cerebrospinal fluid at an extremely high sensitivity without being affected by (1 .fwdarw. 3)-.beta.-D-glucan.

摘要翻译： 本发明提供了一种用于测定内毒素的试剂，其包含鲎变形细胞裂解物和（1→3）-β-D-葡聚糖敏感因子的抗体或包含基本上不含（1-3） - β-D-葡聚糖敏感因子。 本发明的试剂使得可以以极高的灵敏度测定来源于生物样品如血液，尿液和脑脊液中的革兰氏阴性细菌的内毒素，而不受（1-3）-β- D-葡聚糖。

公开(公告)号：US5550030A

公开(公告)日：1996-08-27

申请号：US120469

申请日：1993-09-14

申请人： Shigenori Tanaka ,  Hiroshi Tamura ,  Makoto Ohki

发明人： Shigenori Tanaka ,  Hiroshi Tamura ,  Makoto Ohki

IPC分类号： G03C5/50 ,  G01N33/545 ,  G01N33/548 ,  G01N33/579 ,  G03C7/407 ,  C12Q1/37 ,  C12N11/08 ,  C12N11/12 ,  C12Q1/34

CPC分类号： G01N33/579

摘要： Disclosed are a reagent for endotoxin-specific assay which comprises an insoluble carrier having immobilized thereon at least an endotoxin-sensitive factor derived from a limulus amebocyte; a kit for endotoxin-specific assay containing said reagent and a substrate for activated factor C or a substrate for clotting enzyme; a method for assaying endotoxin comprising applying a sample solution to said reagent to cause endotoxin in the sample to react with factor C in said reagent and determining a change of a substrate; and a process for preparing said reagent which comprises physically or chemically immobilizing at least an endotoxin-sensitive factor derived from a limulus amebocyte on an insoluble carrier. Endotoxin in a sample, even turbid or colored, can be specifically assayed with ease and rapidness without the influence of a (1.fwdarw.3)-.beta.-glucan.

摘要翻译： 公开了一种用于内毒素特异性测定的试剂，其包含其上固定有至少一种源自鲎变形细胞的内毒素敏感因子的不溶性载体; 含有所述试剂和活化因子C的底物或用于凝固酶的底物的内毒素特异性测定试剂盒; 一种用于测定内毒素的方法，包括将样品溶液施加到所述试剂以使样品中的内毒素与所述试剂中的因子C反应并确定底物的变化; 以及制备所述试剂的方法，其包括在不溶性载体上物理或化学地固定来自鲎变形细胞的至少一种内毒素敏感因子。 样品中的内毒素，甚至浑浊或有色，可以在不受（1-> 3）-β-葡聚糖的影响的情况下容易且快速地进行特异性测定。

公开(公告)号：US5474984A

公开(公告)日：1995-12-12

申请号：US246920

申请日：1994-05-20

申请人： Shigenori Tanaka ,  Jun Aketagawa ,  Makoto Ohki ,  Shoji Takahashi ,  Hiroshi Tamura ,  Yuko Shibata

发明人： Shigenori Tanaka ,  Jun Aketagawa ,  Makoto Ohki ,  Shoji Takahashi ,  Hiroshi Tamura ,  Yuko Shibata

IPC分类号： C07H3/06 ,  C08B37/00 ,  G01N33/579 ,  A61K31/715 ,  C08B37/18

CPC分类号： C07H3/06 ,  C08B37/0024 ,  G01N33/579

摘要： This invention relates to a horseshoe crab amebocyte lysate factor G activation inhibitor comprising as an active ingredient a polyglycoside containing at least one poly-(1.fwdarw.3)-.beta.-D-glucoside structure portion consisting of 2 to 370 (1.fwdarw.3)-.beta.-D-glucoside structural units of the following formula ##STR1## which are continuously bound to one another. This inhibitor is useful for inhibiting the activation of factor G which may exist in horseshoe crab amebocyte lysate used in the Limulus test.

摘要翻译： 本发明涉及一种马蹄形褐飞虱细胞裂解物因子G活化抑制剂，其包含作为活性成分的含有至少一种由2至370（1-> 3）组成的聚（1-> 3）-β-D-葡萄糖苷结构部分的多糖苷 ）-β-D-葡萄糖苷结构单元，其结构彼此连续。 该抑制剂可用于抑制鲎试验中使用的马蹄蟹血小板裂解物中可能存在的因子G的活化。

公开(公告)号：US4495294A

公开(公告)日：1985-01-22

申请号：US441810

申请日：1982-11-15

申请人： Chizuko Nakahara ,  Shigenori Tanaka ,  Hiroshi Tamura ,  Akiyoshi Matsumoto

发明人： Chizuko Nakahara ,  Shigenori Tanaka ,  Hiroshi Tamura ,  Akiyoshi Matsumoto

IPC分类号： G01N33/52 ,  G01N33/50 ,  G01N33/579 ,  C12Q1/00 ,  C12Q1/36 ,  C12Q1/38

CPC分类号： G01N33/579 ,  Y10S435/81 ,  Y10T436/25125

摘要： Bacterial endotoxin in an assay sample is determined by an amoebocyte lysate component of horseshoe crab in the presence or absence of a substrate for endotoxin determination by using an assay sample in the liquid state obtained by treating said assay sample with an endotoxin-free acid having a pKa.sup.25.degree. C. value of not more than 3 at a pH of not more than 3; and a kit therefor, a receptacle containing (a) an endotoxin-free acid having a pKa.sup.25.degree. C. value of not more than 3 e.g. perchloric acid, trichloroacetic acid, nitric acid, for treating the assay sample and a receptacle containing (b) an amoebocyte lysate component or horseshoe crab. The acid treatment of the assay sample results in improved accuracy, reliability and reproducibility of the bacterial endotoxin determination.

摘要翻译： 测定样品中的细菌内毒素通过在存在或不存在用于内毒素测定的底物的存在或不存在下测定的测定样品中的细菌内毒素，其通过使用通过用不含内毒素的酸处理所述测定样品获得的液体状态的测定样品，所述测定样品具有 pKa25℃，pH值不大于3时不大于3; 和一种试剂盒，其容器含有（a）pKa25℃值不大于3的无内毒素的酸，例如， 高氯酸，三氯乙酸，硝酸，用于处理测定样品和含有（b）变形细胞裂解物组分或马蹄蟹的容器。 测定样品的酸处理提高了细菌内毒素测定的准确性，可靠性和再现性。