摘要:
A bracket positioned on one side of a membrane or surface is adjustable from the other side of the surface to permit the position of an item supported by the bracket to be readily adjusted relatively to the surface. The bracket has a base to which an arm is movably attached. The arm moves between an open and a closed position to permit the item to be received by the bracket. In the closed position the item is clamped between the base and the arm. A finger is mounted on the base and is movable into and out of engagement with a contact surface on the arm. When the finger engages the contact surface it secures the arm in the closed position and effects the clamping action which holds the item in position. The finger and arm are readily accessible to permit adjustment.
摘要:
A novel electron acceptor based on bay-annulated indigo (BAI) was synthesized and used for the preparation of a series of high performance donor-acceptor small molecules and polymers. The resulting materials possess low-lying LUMO energy level and small HOMO-LUMO gaps, while their films exhibited high crystallinity upon thermal treatment, commensurate with high field effect mobilities and ambipolar transfer characteristics.
摘要:
Systems, methods, and computer-readable media are disclosed for testing a software application. An exemplary method includes storing a control file identifying a test case for testing a software application. A first expect result may be extracted from a device storing expected results of the software application, the first expected result being identified by the control file. A first actual result may be extracted from a device storing actual results output by the software application, the first actual result being identified by the control file. The first expected result may be compared with the first actual result to determine whether the first actual result matches the first expected result. A result file indicated whether the test case passed or failed s generated, and the test case has passed when the first actual result matches the first expected result. the result file may be stored in a storage device.
摘要:
A method of inhibiting phosphatidyl inositol-3 kinase (PI3 kinase), comprising: contacting the PI3 kinase with an effective amount of a compound or pharmaceutically acceptable salt of the formula below, wherein the variables R1, R2, W1, W2, W3, W4, W5, are W6 are defined herein.
摘要:
The present invention provides chemical entities or compounds and pharmaceutical compositions thereof that are capable of modulating lipid kinases such PI3 kinases, tyrosine kinases and protein kinases such as mTOR. For example, the invention provides compounds of Formula: Also provided in the present invention are methods of using these compositions to modulate these kinases especially for therapeutic applications.
摘要:
An apparatus for estimating at least one property of an earth formation is disclosed. The apparatus includes: a carrier configured to be disposed in the formation; a neutron tube disposed at the carrier and located on an axis; a high voltage power source disposed in the carrier and electrically connected to the neutron tube, the high voltage power source located remotely from the neutron tube; and at least one detector disposed in the carrier and located proximate to the neutron tube.
摘要:
The present invention provides for methods and pharmaceutical compositions for treating proliferative disorders. In one aspect, the method comprises administration of two cell-cycle suppressors having a synergistic effect. In another aspect, two cell-cycle suppressors having a synergistic effect are provided in a pharmaceutical composition.
摘要:
Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
摘要:
Disclosed is an apparatus for estimating a property of a fluid. The apparatus includes: a piezoelectric resonator configured to be disposed in the fluid; an electrode embedded in the piezoelectric resonator and included in a resonator circuit configured to output an electrical signal related to the property; a discontinuity defined by a surface of the piezoelectric resonator, the discontinuity altering an impedance of the resonator circuit if a high-dielectric fluid or a conductive fluid is disposed in the discontinuity; and an insulating material disposed in the discontinuity.
摘要:
Chemical entities that modulate PI3 kinase activity, pharmaceutical compositions containing the chemical entities, and methods of using these chemical entities for treating diseases and conditions associated with P13 kinase activity are described herein.