摘要:
The present invention relates to novel oxadiazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
摘要:
The present invention relates to novel N-(imidazolidin-2-ylidene)-heterocyclopenta[b]pyridine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
摘要:
The invention provides compounds represented by the formula I, each of which compounds may have sphingosine-1-phosphate receptor agonist and or antagonist biological activity, wherein these compounds selected from the group consisting of wherein A, B, C, D, X, Y, Z and R3 are defined in the specification. Said compounds are useful for treating a disease or condition of a mammal selected from the group consisting of ocular diseases; systemic vascular barrier related diseases; allergies and other inflammatory diseases; cardiac diseases or conditions; fibrosis; pain and wounds.
摘要:
The present invention relates to method for treating skin diseases and skin conditions in a subject in need of such treatment, which comprises administering a therapeutically effective amount of a composition comprising ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl]methanol, or enantiomers thereof, pharmaceutical compositions containing them and their use as pharmaceuticals.
摘要:
Process for removing peripheral portions such as bead regions of a glass sheet including a step of pushing the glass sheet in the peripheral portion using a pushing mechanism such as a pushing bar, and corresponding apparatus. As a result of the use of the pushing mechanism, the engagement completion time for suction cups, if used, are reduced significantly. A process without using suction cups is enabled with enhanced yield. The increased process stability and enlarged process window are particularly advantageous for processing glass sheets having high flexibility.
摘要:
A mobile refrigeration equipment with DC drive, comprising a heat preservation library body with inner refrigeration system which compressor is DC variable frequency compressor supplied power by second DC voltage and power supply system which consists of double power DC generator that output the first DC voltage and second DC voltage and battery charging with the second DC voltage. The battery and double power DC generator constitute two kinds of power for DC variable frequency compressor. The power controller is linked among the battery, double power DC generator and DC variable frequency compressor. The power controller at least comprises the power switching module which can achieve that, the DC variable frequency compressor is supplied from double power DC generator automatically turning to battery when the vehicle engine is in low speed operating, and the DC variable frequency compressor is supplied from battery automatically turning to double power DC generator when the vehicle engine is in normal speed operating.
摘要:
Embodiments of the present invention provide a domain name system as well as an information processing method and apparatus of the domain name system. The information processing method includes: receiving a domain name system query request sent by a recursive server, where the domain name system query request includes identifier information of a terminal device that sends the query request; resolving the received domain name system query request to obtain the identifier information of the terminal device; and exercising query control according to the identifier information of the terminal device. In the domain name system as well as the information processing method and apparatus of the domain name system, the domain name system query request carries the identifier information of the terminal device that sends the query request, and therefore, effective control is exercised on the information query actions of the terminal device in the domain name system.
摘要:
The present invention provides a method and apparatus for generating index as well as a search method and a search apparatus. Index entry comprises at least a search item identifier corresponding to a search item, one or a plurality of index items generated from one or plural pieces of search information, and an accumulator for the search information. The accumulator is generated by accumulating the search information, or accumulating ciphertext of information containing the search information, or accumulating data mapped from information containing the search information. At the time of searching, the index items and the accumulator are provided to a searcher. The searcher extracts search information from the index items and checks whether the extracted search information is complete by using the accumulator. In one embodiment, the accumulator is incorporated in an encrypted inverted index.
摘要:
The present invention relates to novel phenyl oxadiazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
摘要:
Devices, methods of using the device, systems including the device that include a sample plate with sample containers (wells), wherein at least a portion of the surface of the sample plate and/or sample containers is coated with an optical reflective material. The optical reflective material, provides enhanced excitation signal intensity and enhanced Raman signal intensity. Such enhancement provides improved total signal detection capabilities, and methods of improved focusing algorithms.