摘要:
Key genes, microRNAs, other non-coding RNAs and a combination thereof for identifying and regulating pluripotency of cells are provided. The key genes, microRNAs, other non-coding RNAs and a combination thereof are highly expressed in full pluripotent stem cells but are significantly suppressed or silenced in partially pluripotent stem cells. The genes, microRNAs and other non-coding RNAs are those of a chromosome imprinted Dlk1-Dio3 region located on the long arm of mouse chromosome 12, and are homologous genes, microRNAs and other non-coding RNAs having 70-100% homology with them in genomic syntenic regions of other mammals. Also provided are uses of the genes, microRNAs, other non-coding RNAs and combination thereof in identifying the pluripotent status of stem cells and regulating pluripotency of cells; in typing stem cells; regulating pluripotency of cells, pluripotent states and levels of cells; treating diseases; and developing drug targets for tumor treatment and antitumor drugs.
摘要:
A computer implemented method for creating a depth range buffer for supporting clipping geometries for ray-casting includes inputting image data, establishing a depth range buffer for specifying a start and an end point of each ray, computing a near depth of the image data corresponding to the start point of each ray, computing a far depth of the image data corresponding to the end point of each ray, clipping the volume by restricting ray-casting within the start and end points of the depth range buffer, and rendering a portion of the image data corresponding to the visible depth range.
摘要:
A target outcome fund mimics an option in an underlying risky asset by holding a mix of the risky asset and a low-risk asset. The relative amount of the risky asset and the low risk asset held by the fund is periodically (e.g., monthly) rebalanced based on the fund's performance. If the fund over-performs, the target outcome is increased accordingly to prevent the fund becoming overly invested in the risky asset, thereby protecting gains made.
摘要:
Mip-map construction is provided for three-dimensional rendering from an anisotropic dataset. One or more mip-map levels are generated by down sampling in the world space rather than texture space. The down sampling may be by an arbitrary scale factor rather than a power of two. For example, the voxels may be down sampled along one dimension by less than half (e.g., 16 to 12). The scale factors may be different along different dimensions. This non-uniform reduction in voxels may result in the mip-map being more isotropic than the anisotropic dataset.
摘要:
A method for assessing the cure status of a fibrous blanket manufactured with mineral fibers and binder is disclosed and comprises a using an online optical reflectance measurement as an assessment of cure status. The optical reflectance measurement may preferably be a color image taken of any surface, and in particular of a sectioned face, after which the image is optionally divided into multiple regions of interest (ROI) and analyzed for a color system variable that is representative of cure status. In some embodiments, the color system variable is the B value. Alternatively, the optical reflectance measurement may be UV or IR reflectance of a sectioned face. When two or more regions of interest are defined on a sectioned face, comparative information is valuable to assess cure at different levels, layers or portions of the interior of the fibrous product.
摘要:
An engine powered wheeled machine having improved engine over speed and under speed protection includes a parallel path transmission having a gear train with first and second transmission inputs and a transmission output, and including a hydraulic variator having a variator output driving the first transmission input, the hydraulic variator having a variator pump and a variator motor, the displacement of the variator pump being controlled by a variator actuator. The machine further includes an engine having an engine output driving the second transmission input and driving the variator pump and a controller for receiving one or more values indicative of one or more ranges of permissible engine speed, a value indicative of an actual engine speed, and a value indicative of the position of the variator actuator, with the controller being configured to control the position of the variator actuator based on state space gain mapping to maintain the engine speed within the one or more ranges of permissible engine speed.
摘要:
A user data engine residing on an endpoint machine generates a current user context reflecting a specific flow of operations performed by an end-user when interacting with a software application. A context engine residing on a sever machine compares the current user context to one or more stored user contexts included in a context database and generates a similarity value based on each comparison. A resource engine identifies resources in a resource database that are associated with the stored user contexts and then generates a relevance score for each resource based on the similarity scores corresponding to the stored user contexts with which those resources are associated. The resource engine transmits a resource list reflecting the identified resources to the user data engine based on the relevance scores. The user data engine displays on a display screen of the endpoint machine information associated with resources reflected in the resource list.
摘要:
Following a cold start of a hydrocarbon-fueled engine operated in a lean-burn-combustion mode, several seconds and minutes may be required for the exhaust gas stream to heat exhaust treatment devices in the exhaust system and conduit to their effective operating temperatures. The warm-up period may be particularly long for a NOx reduction catalyst (SCR) located downstream in the exhaust flow system. Accordingly, a bed of absorbent material, such as a suitably sized bed of alumina particles, located upstream of the SCR, is used to temporarily absorb water and NOx from a relatively cold exhaust until the exhaust has suitably heated the SCR to its operating temperature. Then, the warmed exhaust will remove the water and NOx from their temporary storage material and carry them to the reduction catalyst.
摘要:
Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis-related diseases.