KEY GENES, MICRORNAS, OTHER NON-CODING RNAS AND COMBINATION THEREOF FOR IDENTIFYING AND REGULATING THE PLURIPOTENT STATUS OF CELLS
    51.
    发明申请
    KEY GENES, MICRORNAS, OTHER NON-CODING RNAS AND COMBINATION THEREOF FOR IDENTIFYING AND REGULATING THE PLURIPOTENT STATUS OF CELLS 审中-公开
    关键基因,微阵列,其他非编码RNA及其组合,用于鉴定和调节细胞的细胞核状态

    公开(公告)号:US20130035241A1

    公开(公告)日:2013-02-07

    申请号:US13639664

    申请日:2010-04-07

    CPC分类号: C12Q1/6881 C12Q2600/178

    摘要: Key genes, microRNAs, other non-coding RNAs and a combination thereof for identifying and regulating pluripotency of cells are provided. The key genes, microRNAs, other non-coding RNAs and a combination thereof are highly expressed in full pluripotent stem cells but are significantly suppressed or silenced in partially pluripotent stem cells. The genes, microRNAs and other non-coding RNAs are those of a chromosome imprinted Dlk1-Dio3 region located on the long arm of mouse chromosome 12, and are homologous genes, microRNAs and other non-coding RNAs having 70-100% homology with them in genomic syntenic regions of other mammals. Also provided are uses of the genes, microRNAs, other non-coding RNAs and combination thereof in identifying the pluripotent status of stem cells and regulating pluripotency of cells; in typing stem cells; regulating pluripotency of cells, pluripotent states and levels of cells; treating diseases; and developing drug targets for tumor treatment and antitumor drugs.

    摘要翻译: 提供了关键基因,微小RNA,其他非编码RNA及其组合,用于鉴定和调节细胞多能性。 关键基因,微小RNA,其他非编码RNA及其组合在全多能干细胞中高度表达,但在部分多能干细胞中被显着抑制或沉默。 基因,微小RNA和其他非编码RNA是位于小鼠染色体12的长臂上的染色体印记的Dlk1-Dio3区域,是同源基因,微小RNA和其他与它们具有70-100%同源性的非编码RNA 在其他哺乳动物的基因组复合区。 还提供了基因,微小RNA,其他非编码RNA及其组合在鉴定干细胞的多能性和调节细胞多能性的用途; 在干细胞分类中; 调节细胞的多能性,多能状态和细胞水平; 治疗疾病; 并开发用于肿瘤治疗和抗肿瘤药物的药物靶标。

    Clipping geometries in ray-casting
    52.
    发明授权
    Clipping geometries in ray-casting 有权
    在射线铸造中剪切几何

    公开(公告)号:US08368692B2

    公开(公告)日:2013-02-05

    申请号:US12120329

    申请日:2008-05-14

    申请人: Wei Li

    发明人: Wei Li

    IPC分类号: G06T15/40

    摘要: A computer implemented method for creating a depth range buffer for supporting clipping geometries for ray-casting includes inputting image data, establishing a depth range buffer for specifying a start and an end point of each ray, computing a near depth of the image data corresponding to the start point of each ray, computing a far depth of the image data corresponding to the end point of each ray, clipping the volume by restricting ray-casting within the start and end points of the depth range buffer, and rendering a portion of the image data corresponding to the visible depth range.

    摘要翻译: 用于创建用于支持用于射线投射的裁剪几何的深度范围缓冲器的计算机实现方法包括输入图像数据,建立用于指定每个射线的开始和结束点的深度范围缓冲器,计算对应于 每个射线的起始点,计算对应于每个射线的终点的图像数据的深度,通过限制在深度范围缓冲区的开始和结束点内的射线投射来限制体积,并且渲染一部分 对应于可见深度范围的图像数据。

    TARGET OUTCOME FUND
    54.
    发明申请
    TARGET OUTCOME FUND 有权
    目标成果基金

    公开(公告)号:US20120330796A1

    公开(公告)日:2012-12-27

    申请号:US13460562

    申请日:2012-04-30

    IPC分类号: G06Q40/06 G06Q40/04

    CPC分类号: G06Q40/04 G06Q40/06

    摘要: A target outcome fund mimics an option in an underlying risky asset by holding a mix of the risky asset and a low-risk asset. The relative amount of the risky asset and the low risk asset held by the fund is periodically (e.g., monthly) rebalanced based on the fund's performance. If the fund over-performs, the target outcome is increased accordingly to prevent the fund becoming overly invested in the risky asset, thereby protecting gains made.

    摘要翻译: 目标结果基金通过持有风险资产和低风险资产的组合来模拟潜在风险资产中的期权。 资金持有的风险资产和低风险资产的相对金额按照基金的表现定期(例如每月)重新平衡。 如果基金过剩,目标结果相应增加,防止资金过度投资于风险资产,从而保护收益。

    MIP-map for rendering of an anisotropic dataset
    55.
    发明授权
    MIP-map for rendering of an anisotropic dataset 有权
    用于渲染各向异性数据集的MIP映射

    公开(公告)号:US08314811B2

    公开(公告)日:2012-11-20

    申请号:US11692232

    申请日:2007-03-28

    申请人: Wei Li

    发明人: Wei Li

    IPC分类号: G09G5/00 G06T17/00

    CPC分类号: G06T15/04

    摘要: Mip-map construction is provided for three-dimensional rendering from an anisotropic dataset. One or more mip-map levels are generated by down sampling in the world space rather than texture space. The down sampling may be by an arbitrary scale factor rather than a power of two. For example, the voxels may be down sampled along one dimension by less than half (e.g., 16 to 12). The scale factors may be different along different dimensions. This non-uniform reduction in voxels may result in the mip-map being more isotropic than the anisotropic dataset.

    摘要翻译: 为各向异性数据集的三维渲染提供了Mip-map构造。 通过在世界空间中的下采样而不是纹理空间来生成一个或多个mip-map级别。 下采样可以是任意比例因子而不是二的幂。 例如,体素可以沿着一个维度减少少于一半(例如,16至12)。 不同尺寸的比例因子可能不同。 体素的这种不均匀的减少可能导致mip-map比各向异性数据集更具各向同性。

    METHOD FOR ONLINE DETERMINATION OF CURE STATUS OF GLASS FIBER PRODUCTS
    56.
    发明申请
    METHOD FOR ONLINE DETERMINATION OF CURE STATUS OF GLASS FIBER PRODUCTS 有权
    用于在线确定玻璃纤维产品的固化状态的方法

    公开(公告)号:US20120268586A1

    公开(公告)日:2012-10-25

    申请号:US13089457

    申请日:2011-04-19

    IPC分类号: H04N7/18

    CPC分类号: G01N21/55 G01N21/25

    摘要: A method for assessing the cure status of a fibrous blanket manufactured with mineral fibers and binder is disclosed and comprises a using an online optical reflectance measurement as an assessment of cure status. The optical reflectance measurement may preferably be a color image taken of any surface, and in particular of a sectioned face, after which the image is optionally divided into multiple regions of interest (ROI) and analyzed for a color system variable that is representative of cure status. In some embodiments, the color system variable is the B value. Alternatively, the optical reflectance measurement may be UV or IR reflectance of a sectioned face. When two or more regions of interest are defined on a sectioned face, comparative information is valuable to assess cure at different levels, layers or portions of the interior of the fibrous product.

    摘要翻译: 公开了一种评估用矿物纤维和粘合剂制造的纤维毯的固化状态的方法,并且包括使用在线光学反射测量作为固化状态的评估。 光学反射率测量可以优选地是从任何表面拍摄的彩色图像,特别是分割面,之后图像可选地分成多个感兴趣区域(ROI),并且分析代表固化的颜色系统变量 状态。 在一些实施例中,颜色系统变量是B值。 或者,光反射率测量可以是截面的UV或IR反射率。 当在切片面上限定两个或更多个感兴趣区域时,比较信息对于评估在纤维制品内部的不同水平,层或部分上的固化是有价值的。

    CVT control using state space based gain scheduling
    57.
    发明申请
    CVT control using state space based gain scheduling 有权
    使用基于状态空间的增益调度的CVT控制

    公开(公告)号:US20120253631A1

    公开(公告)日:2012-10-04

    申请号:US13077694

    申请日:2011-03-31

    申请人: Wei Li Brian D. Hoff

    发明人: Wei Li Brian D. Hoff

    IPC分类号: G06F19/00

    摘要: An engine powered wheeled machine having improved engine over speed and under speed protection includes a parallel path transmission having a gear train with first and second transmission inputs and a transmission output, and including a hydraulic variator having a variator output driving the first transmission input, the hydraulic variator having a variator pump and a variator motor, the displacement of the variator pump being controlled by a variator actuator. The machine further includes an engine having an engine output driving the second transmission input and driving the variator pump and a controller for receiving one or more values indicative of one or more ranges of permissible engine speed, a value indicative of an actual engine speed, and a value indicative of the position of the variator actuator, with the controller being configured to control the position of the variator actuator based on state space gain mapping to maintain the engine speed within the one or more ranges of permissible engine speed.

    摘要翻译: 具有改进的发动机超速和低速保护的发动机驱动的轮式发动机包括具有带有第一和第二变速器输入和变速器输出的齿轮系的并行路径变速器,并且包括具有驱动第一变速器输入的变速器输出的液压变速器, 具有变速泵和变速马达的液压变速器,变速泵的位移由变速器致动器控制。 该机器还包括具有驱动第二变速器输入并驱动变速泵的发动机输出的发动机和用于接收表示允许的发动机转速的一个或多个范围,表示实际发动机转速的值的一个或多个值的控制器,以及 指示变速器致动器的位置的值,其中控制器被配置为基于状态空间增益映射来控制变换器致动器的位置,以将发动机速度维持在允许的发动机转速的一个或多个范围内。

    Displaying resources based on shared contexts

    公开(公告)号:US08271410B2

    公开(公告)日:2012-09-18

    申请号:US12431657

    申请日:2009-04-28

    IPC分类号: G06F17/00 G06F15/18 G06F7/00

    CPC分类号: G06N99/005 G06F9/453

    摘要: A user data engine residing on an endpoint machine generates a current user context reflecting a specific flow of operations performed by an end-user when interacting with a software application. A context engine residing on a sever machine compares the current user context to one or more stored user contexts included in a context database and generates a similarity value based on each comparison. A resource engine identifies resources in a resource database that are associated with the stored user contexts and then generates a relevance score for each resource based on the similarity scores corresponding to the stored user contexts with which those resources are associated. The resource engine transmits a resource list reflecting the identified resources to the user data engine based on the relevance scores. The user data engine displays on a display screen of the endpoint machine information associated with resources reflected in the resource list.