Canine CYP1A2 genetic polymorphism
    51.
    发明授权
    Canine CYP1A2 genetic polymorphism 失效
    犬CYP1A2遗传多态性

    公开(公告)号:US07399587B2

    公开(公告)日:2008-07-15

    申请号:US10536809

    申请日:2004-05-28

    IPC分类号: C07H21/04 C12Q1/68

    摘要: Disclosed is a method for determining whether a dog is an extensive metabolizer or a poor metabolizer in the rate of drug metabolism, by preparing a DNA sample from a dog, and determining a base corresponding to a base at position 1117 of a canine CYP1A2 gene (i.e., at position 87 of exon 4). According to the method, a CYP1A2 gene diagnosis of dogs (particularly beagles) used in a pharmacological effect test or a toxicity test can be rapidly carried out prior to the test, and thus the dogs can be easily divided into a group having a normal metabolic ability (an extensive metabolizer group) and a group having a low metabolic ability (a poor metabolizer group).

    摘要翻译: 公开了一种用于通过从狗制备DNA样品以及确定对应于犬CYP1A2基因的第1117位的碱基的碱基来确定狗是否是药物代谢速率中广泛的代谢者或不良代谢者的方法( 即外显子4的位置87)。 根据该方法,可以在试验前快速进行用于药理作用试验或毒性试验的狗(特别是be角)的CYP1A2基因诊断,因此可以容易地将狗分为具有正常代谢的组 能力(广泛的代谢组)和代谢能力低的组(代谢组较差)。

    Thin-film magnetic head with gap and pole portion layers having cross sections of the same shapes and predetermined parameter ranges
    52.
    发明授权
    Thin-film magnetic head with gap and pole portion layers having cross sections of the same shapes and predetermined parameter ranges 失效
    具有间隙和极部分层的薄膜磁头具有相同形状和预定参数范围的横截面

    公开(公告)号:US07248435B2

    公开(公告)日:2007-07-24

    申请号:US10827632

    申请日:2004-04-20

    IPC分类号: G11B5/31 G11B5/23 G11B5/39

    CPC分类号: G11B5/3906

    摘要: A bottom pole layer and a top pole layer respectively incorporate pole portion layers. Cross sections of the pole portion layers and a gap layer parallel to the top surface of a substrate are of the same shapes. The aggregate of the pole portion layers and the gap layer includes a first portion having a width W that defines the track width, and a second portion having a width greater than the width W of the first portion. L/W falls within a range of 2 to 5 inclusive, where L is the distance from a medium facing surface to the interface between the first portion and the second portion. S/(W×L) falls within a range of 5 to 40 inclusive, where S is the area of the cross section of the aggregate parallel to the top surface of the substrate.

    摘要翻译: 底极层和顶极层分别包括极部分层。 极性部分层的横截面和与衬底的顶表面平行的间隙层具有相同的形状。 极部分层和间隙层的聚集体包括具有限定轨道宽度的宽度W的第一部分和宽度大于第一部分宽度W的第二部分。 L / W落在2到5的范围内,其中L是从介质面向表面到第一部分和第二部分之间的界面的距离。 S /(WxL)在5〜40的范围内,其中S是与基板的顶面平行的集合体的横截面积。

    Canine cyp1a2 genetic polymorphism
    53.
    发明申请
    Canine cyp1a2 genetic polymorphism 失效
    犬cyp1a2遗传多态性

    公开(公告)号:US20060051766A1

    公开(公告)日:2006-03-09

    申请号:US10536809

    申请日:2004-05-28

    IPC分类号: C12Q1/68 C07H21/04

    摘要: Disclosed is a method for determining whether a dog is an extensive metabolizer or a poor metabolizer in the rate of drug metabolism, by preparing a DNA sample from a dog, and determining a base corresponding to a base at position 1117 of a canine CYP1A2 gene (i.e., at position 87 of exon 4). According to the method, a CYP1A2 gene diagnosis of dogs (particularly beagles) used in a pharmacological effect test or a toxicity test can be rapidly carried out prior to the test, and thus the dogs can be easily divided into a group having a normal metabolic ability (an extensive metabolizer group) and a group having a low metabolic ability (a poor metabolizer group).

    摘要翻译: 公开了一种用于通过从狗制备DNA样品以及确定对应于犬CYP1A2基因的第1117位的碱基的碱基来确定狗是否是药物代谢速率中广泛的代谢者或不良代谢者的方法( 即外显子4的位置87)。 根据该方法,可以在试验前快速进行用于药理作用试验或毒性试验的狗(特别是be角)的CYP1A2基因诊断,因此可以容易地将狗分为具有正常代谢的组 能力(广泛的代谢组)和代谢能力低的组(代谢组较差)。

    Thin film magnetic head
    54.
    发明申请
    Thin film magnetic head 失效
    薄膜磁头

    公开(公告)号:US20050195526A1

    公开(公告)日:2005-09-08

    申请号:US11068967

    申请日:2005-03-02

    IPC分类号: G11B5/31 G11B5/147

    CPC分类号: G11B5/3116 G11B5/1278

    摘要: The present invention is intended for a thin film magnetic head which can provide reduction in the excess magnetostatic leakage field even if the flare point is set near to the ABS in order to generate a sufficient recording magnetic field and which can assure stable overwrite characteristics even if there are variations in upper pole portion patterns. The pole end portion 223 has a width W11 to define a recording track width. The pole rear portion 222 has one end which is magnetically connected with the pole end portion 223 at or in the vicinity of an edge portion of an insulating film 273 and defines a first flare point FP1, the other end which is connected with the upper yoke portion 221 and defines a second flare point FP2, and both side edges in the track width direction which are inclined so that the width in the track width direction gradually increases from the second flare point FP2 toward the first flare point FP1. The width W11 of the pole end portion 223 at the first flare point FP1 is smaller than the maximum width W21 of the pole rear portion 222.

    摘要翻译: 本发明的目的在于一种薄膜磁头,即使将扩张点设置在靠近ABS的情况下也能够提供过剩的静磁泄漏场,以产生足够的记录磁场,即使在 上极部分图形有变化。 极端部223具有宽度W 11,以限定记录轨道宽度。 极后部222的一端在绝缘膜273的边缘部分处或附近与极端部223磁性连接,并且限定第一扩口点FP1,另一端与上端 轭部221,并且限定第二扩张点FP 2,以及轨道宽度方向上的两个侧边缘,其倾斜,使得轨道宽度方向上的宽度从第二扩张点FP 2朝向第一扩张点FP 1逐渐增加。 第一点火点FP 1的极端部223的宽度W 11比极后部222的最大宽度W 21小。

    Thin-film magnetic head having magnetic layers of different thicknesses and fabrication method for same
    55.
    发明申请
    Thin-film magnetic head having magnetic layers of different thicknesses and fabrication method for same 失效
    具有不同厚度的磁性层的薄膜磁头及其制造方法

    公开(公告)号:US20050057851A1

    公开(公告)日:2005-03-17

    申请号:US10917476

    申请日:2004-08-13

    IPC分类号: G11B5/127 G11B5/31

    摘要: A thin-film magnetic head includes a lower magnetic layer, an upper magnetic layer, a recording gap layer, and a thin-film coil. The lower magnetic layer has a first magnetic pole tip layer, and a first yoke layer which is connected to the first magnetic pole tip layer. The first yoke layer has an extended part which is relatively thick and a reduced part which is relatively thin in the area in which the first yoke layer confronts the first magnetic pole tip layer, the extended part being positioned on the side of the air bearing surface. Further, the first magnetic pole tip layer is connected to the first yoke layer at the extended part, and is insulated from the first yoke layer at the reduced part.

    摘要翻译: 薄膜磁头包括下磁性层,上磁性层,记录间隙层和薄膜线圈。 下磁性层具有第一磁极尖端层和与第一磁极尖端层连接的第一磁轭层。 第一磁轭层具有相对较厚的延伸部分和在第一磁轭层面对第一磁极末端层的区域中较薄的部分,延伸部分位于空气轴承表面侧 。 此外,第一磁极尖端层在延伸部分处连接到第一磁轭层,并且在缩小部分处与第一磁轭层绝缘。

    Magnetic recording medium of particular coercive force, filling ratio,
and protrusions and recording/reproducing method therefor
    56.
    发明授权
    Magnetic recording medium of particular coercive force, filling ratio, and protrusions and recording/reproducing method therefor 失效
    具有特定矫顽力,填充率和突起的磁记录介质及其记录/再现方法

    公开(公告)号:US4816933A

    公开(公告)日:1989-03-28

    申请号:US789842

    申请日:1985-10-21

    摘要: A magnetic recording medium is provided comprising a flexible substrate and a ferromagnetic metal thin film layer on the substrate primarily comprising cobalt. When coercive force is measured by changing the measuring direction in a plane defined by a longitudinal direction of the substrate and a direction normal to the major surface of the substrate, the following relationship is met:(Hc.sub.max -Hc.sub.min)/Hc(O).ltoreq.0.9where Hc.sub.max is the maximum of the coercive force, Hc.sub.min is the minimum of the coercive force, and Hc(O) is a coercive force in the longitudinal direction of the substrate. The medium has in average at least 10.sup.5 /a.sup.2 protrusions per square millimeter of the surface, the protrusions having a height of 30 to 300 .ANG., where a is the distance as expressed in .mu.m of a gap in a magnetic head across which the medium is passed for recording and reproducing operation. The filling ratio of the ferromagnetic metal thin film layer is at least 0.7.

    摘要翻译: 提供了一种磁记录介质,其包括柔性基底和主要包含钴的基底上的强磁性金属薄膜层。 通过在由基板的纵向和垂直于基板的主表面的方向限定的平面中改变测量方向来测量矫顽力时,满足以下关系:(Hcmax-Hcmin)/ Hc(O) /=0.9其中Hcmax是矫顽力的最大值,Hcmin是矫顽力的最小值,Hc(O)是衬底纵向上的矫顽力。 介质平均每平方毫米表面至少有105 / a2个突起,突起的高度为30至300安培,其中a为磁头间隙的距离,以m为单位, 通过记录和再现操作。 强磁性金属薄膜层的填充率为0.7以上。

    Process for producing a magnetic recording medium
    58.
    发明授权
    Process for producing a magnetic recording medium 失效
    磁记录介质的制造方法

    公开(公告)号:US4540600A

    公开(公告)日:1985-09-10

    申请号:US588890

    申请日:1984-03-12

    摘要: A process for producing a magnetic recording medium which comprises forming on a non-magnetic substrate a magnetic thin layer composed of columnar crystal particles comprising Co, or Co and Ni and/or Cr by vapor/depositing the metal atoms at an angle of incidence of at least 20.degree. relative to the normal line of the principal plane of the substrate, and then forcibly oxidizing the magnetic thin layer by electrochemical treatment to form an oxide layer on the surface of the columnar crystal particles of the magnetic thin layer, and thereby to form a magnetic layer.

    摘要翻译: 一种磁记录介质的制造方法,其特征在于,在非磁性基板上形成由包含Co,或Co,Ni和/或Cr的柱状结晶粒子构成的磁性薄膜,所述磁性薄膜由蒸气/沉积金属原子以入射角 相对于基板的主面的法线为至少20°,然后通过电化学处理强制氧化磁性薄层,以在磁性薄层的柱状结晶粒子的表面上形成氧化物层,从而 形成磁性层。

    Magnetoresistive effect element in CPP-type structure and magnetic disk device
    59.
    发明授权
    Magnetoresistive effect element in CPP-type structure and magnetic disk device 有权
    CPP型结构和磁盘装置中的磁阻效应元件

    公开(公告)号:US08154828B2

    公开(公告)日:2012-04-10

    申请号:US12500835

    申请日:2009-07-10

    IPC分类号: G11B5/39

    摘要: An MR element in a CPP structure includes a spacer layer made of Cu, a magnetic pinned layer containing CoFe and a free layer containing CoFe that are laminated to sandwich the spacer layer. The free layer is located below the magnetic pinned layer. The free layer is oriented in a (001) crystal plane, the spacer layer is formed and oriented in a (001) crystal plane on the (001) crystal plane of the free layer. Therefore, in a low resistance area where an area resistivity (AR) of the MR element is, for example, lower than 0.3 Ω·μm2, an MR element that has a large variation of a resistance is obtained.

    摘要翻译: CPP结构中的MR元件包括由Cu制成的间隔层,包含CoFe的磁性固定层和层压以夹持间隔层的CoFe的自由层。 自由层位于磁性固定层的下方。 自由层在(001)晶面取向,间隔层形成并定向在自由层的(001)晶面上的(001)晶面上。 因此,在MR元件的面积电阻率(AR)例如低于0.3

    MICROWAVE ASSISTED MAGNETIC HEAD
    60.
    发明申请
    MICROWAVE ASSISTED MAGNETIC HEAD 有权
    MICROWAVE辅助磁头

    公开(公告)号:US20110242696A1

    公开(公告)日:2011-10-06

    申请号:US12750870

    申请日:2010-03-31

    IPC分类号: G11B5/02

    摘要: A gap between a main pole and auxiliary pole composing a thin film magnetic head having a microwave assisted function of the present invention is filled with a nonmagnetic dielectric layer to embed a microwave radiator. The nonmagnetic dielectric layer has an inclined surface at a end on a side of an opposing medium surface by which the microwave radiated from the microwave radiator to be bent toward the main pole, whereby the microwave magnetic field generated from the microwave generator can be gathered immediately below the main pole, further improving the microwave assisted effect.

    摘要翻译: 构成本发明的具有微波辅助功能的薄膜磁头的主极和辅助极之间的间隙填充有非磁性介电层以嵌入微波辐射器。 非磁性介电层在相对的介质表面的一侧的端部具有倾斜表面,微波从微波辐射器辐射到微波辐射器,从而微波发生器产生的微波磁场可以立即收集 主杆下方进一步提高微波辅助效果。