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    Methods and Systems for Clinical Trial Data Management
    51.
    发明申请
    Methods and Systems for Clinical Trial Data Management 有权
    临床试验数据管理方法与系统

    公开(公告)号：US20060259783A1

    公开(公告)日：2006-11-16

    申请号：US11380626

    申请日：2006-04-27

    申请人： William Work ,  Telford Work ,  Masashi Ito

    发明人： William Work ,  Telford Work ,  Masashi Ito

    IPC分类号： G06F12/14

    CPC分类号： G06Q10/10 ,  G06F19/00 ,  G16H10/20

    摘要： The invention provides systems and methods for creating certified copies of original information, including original hardcopy documents, in compliance with federal regulations and guidelines. The present invention also provides systems and methods of data management, and in particular, management of such certified copies. In some embodiments the invention relates to original clinical trial information such as source documents, and methods and systems for creating certified copies of such information to create an accessible central repository of such certified copies.

    摘要翻译： 本发明提供了根据联邦法规和指南，创建原始信息的认证副本（包括原始硬拷贝文件）的系统和方法。 本发明还提供数据管理的系统和方法，特别是管理这种认证副本。 在一些实施方案中，本发明涉及原始临床试验信息，例如源文件，以及用于创建这种信息的认证副本的方法和系统，以创建这种认证副本的可访问中央存储库。

    Quinuclidine compounds and drugs containing the same as the active ingredient
    54.
    发明授权
    Quinuclidine compounds and drugs containing the same as the active ingredient 失效
    奎宁环化合物和含有与活性成分相同的药物

    公开(公告)号：US06599917B1

    公开(公告)日：2003-07-29

    申请号：US10088554

    申请日：2002-03-19

    申请人： Toshimi Okada ,  Nobuyuki Kurusu ,  Keigo Tanaka ,  Kazuki Miyazaki ,  Daisuke Shinmyo ,  Hiroyuki Sugumi ,  Hironori Ikuta ,  Hironobu Hiyoshi ,  Takao Saeki ,  Mamoru Yanagimachi ,  Masashi Ito

    发明人： Toshimi Okada ,  Nobuyuki Kurusu ,  Keigo Tanaka ,  Kazuki Miyazaki ,  Daisuke Shinmyo ,  Hiroyuki Sugumi ,  Hironori Ikuta ,  Hironobu Hiyoshi ,  Takao Saeki ,  Mamoru Yanagimachi ,  Masashi Ito

    IPC分类号： A61K31439

    CPC分类号： C07D453/02

    摘要： The present invention provides an excellent squalene synthesizing enzyme inhibitor. Specifically, it provides a compound (I) represented by the following formula, a salt thereof or a hydrate of them. In which R1 represents (1) hydrogen atom or (2) hydroxyl group; HAr represents an aromatic heterocycle which may be substituted with 1 to 3 groups; Ar represents an optionally substituted aromatic ring; W represents a chain represented by (1) —CH2—CH2— which may be substituted, (2) —CH═CH— which may be substituted, (3) —C≡C—, (4) —NH—CO—, (5) —CO—NH—, (6) —NH—CH2—, (7) —CH2—NH—, (8) —CH2—CO—, (9) —CO—CH2—, (10) —NH—S(O)l—, (11) —S(O)l—NH—, (12) —CH2—S(O)— or (13) —S(O)l—CH2— (l denotes 0, 1 or 2); and X represents a chain represented by (1) a single bond, (2) an optionally substituted C1-6 alkylene chain, (3) an optionally substituted C2-6 alkenylene chain, (4) an optionally substituted C2-6 alkynylene chain, (5) a formula —Q— (wherein Q represents oxygen atom, sulfur atom, CO or N(R2) (wherein R2 represents a C1-6 alkyl group or a C1-6 alkoxy group)), (6) —NH—CO—, (7) —CO—NH—, (8) —NH—CH2—, (9) —CH2—NH—, (10) —CH2—CO—, (11) —CO—CH2—, (12) —NH—S(O)m—, (13) —S(O)m—NH—, (14) —CH2—S(O)m—, (15) —S(O)m—CH2— (wherein m denotes 0, 1 or 2) or (16) —(CH2)n—O— (wherein n denotes an integer from 1 to 6).

    摘要翻译： 本发明提供优良的角鲨烯合成酶抑制剂。 具体地说，它提供由下式表示的化合物（I），其盐或它们的水合物。其中R1表示（1）氢原子或（2）羟基; HAr表示可被1〜3个基团取代的芳香族杂环; Ar表示任选取代的芳环; W表示可被取代的（1）-CH 2 -CH 2 - 表示的链，（2）可以被取代的-CH = CH-，（3）-C = C-，（4）-NH-CO-， （5）-CO-NH-，（6）-NH-CH2-，（7）-CH2-NH-，（8）-CH2-CO-，（9）-CO-CH2-，（10）-NH -S（O）1 - ，（11）-S（O）1 -NH-，（12）-CH 2 -S（O） - 或（13）-S（O） 1或2）; 并且X表示由（1）单键表示的链，（2）任选取代的C 1-6亚烷基链，（3）任选取代的C 2-6亚烯基链，（4）任选取代的C 2-6亚炔基链， （5）式-Q-（其中Q表示氧原子，硫原子，CO或N（R2）（其中R2表示C1-6烷基或C1-6烷氧基）），（6）-NH- CO-，（7）-CO-NH-，（8）-NH-CH2-，（9）-CH2-NH-，（10）-CH2-CO-，（11）-CO-CH2-， ）-NH-S（O）m - ，（13）-S（O）m -NH-，（14）-CH 2 -S（O）m - ，（15）-S（O）m -CH 2 - 其中m表示0,1或2）或（16） - （CH2）nO-（其中n表示1至6的整数）。

    Fuel vapor treatment system
    55.
    发明授权
    Fuel vapor treatment system 失效
    燃油蒸气处理系统

    公开(公告)号：US06569228B2

    公开(公告)日：2003-05-27

    申请号：US09838275

    申请日：2001-04-20

    申请人： Masashi Ito

    发明人： Masashi Ito

    IPC分类号： B01D5302

    CPC分类号： F02M33/08 ,  B01D53/229 ,  F02M25/089 ,  F02M33/02 ,  F02M2025/0881

    摘要： A fuel vapor treatment system for an automotive vehicle on which an internal combustion engine is mounted. The fuel vapor treatment system includes a canister connected to a fuel tank and containing a fuel vapor adsorbing material which generates endothermic energy during desorption of fuel vapor. A membrane separation module is provided to be connected to the canister and including a separation membrane for separating a mixture gas purged from the canister into an air-rich component and a fuel vapor-rich component. Additionally, a condenser is provided to be connected to the membrane separation module to be supplied with the fuel vapor-rich component from the membrane separation module. The condenser is housed in the canister and adapted to cool and liquefy fuel vapor in the fuel vapor-rich component to obtain liquefied fuel by the endothermic energy generated in the canister, the liquefied fuel being recovered.

    摘要翻译： 一种用于其上安装有内燃机的机动车辆的燃料蒸气处理系统。 燃料蒸汽处理系统包括连接到燃料箱并且包含在燃料蒸汽解吸期间产生吸热能的燃料蒸汽吸附材料的罐。 提供了一种膜分离模块，其与罐连接并且包括用于将从罐排出的混合气体分离成富含空气的组分和富含燃料蒸气的组分的分离膜。 此外，提供冷凝器以连接到膜分离模块以从膜分离模块供应富燃料蒸气组分。 冷凝器容纳在罐中并适于冷却和液化富燃料组分中的燃料蒸汽，以通过在罐中产生的吸热能量来获得液化燃料，液化燃料被回收。

    Device for clamping a workpiece
    57.
    发明授权
    Device for clamping a workpiece 失效
    夹紧工件的装置

    公开(公告)号：US5330168A

    公开(公告)日：1994-07-19

    申请号：US9074

    申请日：1993-01-26

    申请人： Minoru Enomoto ,  Shoji Inagaki ,  Yasuhiro Okada ,  Fumio Sakamoto ,  Noritaka Ise ,  Masashi Ito ,  Fuyuhiko Yoshikura

    发明人： Minoru Enomoto ,  Shoji Inagaki ,  Yasuhiro Okada ,  Fumio Sakamoto ,  Noritaka Ise ,  Masashi Ito ,  Fuyuhiko Yoshikura

    IPC分类号： B23Q3/06 ,  B23Q17/00 ,  B25B5/16 ,  B25B1/10

    CPC分类号： B23Q3/069 ,  B23Q17/002 ,  B25B5/16

    摘要： A clamping device which holds a workpiece at a predetermined position during a machining operation of the workpiece comprises a clamper for clamping a workpiece, a feed device for moving the clamper in the axial direction, a load sensor which is fixed to the clamper and detects a clamping force acting on the workpiece, and a memory in which a target clamping force corresponding to the shape of the workpiece and a method of machining operation is stored. The control device compares the clamping force detected by the load sensor with the target clamping force stored in the memory and controls the clamper in response to the deviation between the detected clamping force and the target clamping force. The clamping device also has a position detecting means for detecting the axial position of the clamper. The control device compares the present position detected by the position detecting means with a stop position which is detected during the initial clamping and is stored in the memory, and controls the clamper in proportion to the deviation between the detected position and the stored stop position.

    摘要翻译： 在工件的加工操作期间将工件保持在预定位置的夹紧装置包括用于夹持工件的夹持器，用于沿轴向移动夹持器的进给装置，固定到夹持器的负载传感器， 作用在工件上的夹紧力和存储有与工件的形状相对应的目标夹紧力和存储加工操作的方法的存储器。 控制装置将由负载传感器检测到的夹紧力与存储在存储器中的目标夹紧力进行比较，并响应于检测到的夹紧力和目标夹紧力之间的偏差来控制夹持器。 夹持装置还具有用于检测夹持器的轴向位置的位置检测装置。 控制装置将由位置检测装置检测的当前位置与在初始夹紧期间检测到的停止位置进行比较，并存储在存储器中，并且与检测位置和存储的停止位置之间的偏差成比例地控制夹持器。

    Objective lens driving unit
    58.
    发明授权
    Objective lens driving unit 失效
    物镜驱动单元

    公开(公告)号：US4842392A

    公开(公告)日：1989-06-27

    申请号：US52922

    申请日：1987-05-22

    申请人： Hiroyuki Nakamura ,  Masashi Ito ,  Toshiki Itoi ,  Akifumi Hashimoto

    发明人： Hiroyuki Nakamura ,  Masashi Ito ,  Toshiki Itoi ,  Akifumi Hashimoto

    IPC分类号： G11B7/09

    CPC分类号： G11B7/093

    摘要： In an objective lens driving unit, an objective lens (12) is fixed to a coil bobbin (11), which has a focus drive coil (13a) wound therearound with its axis coaxial with the axis of the objective lens (12) and tracking dive coils (13b, 13c) wound thereon with their axes perpendicular with the axis of the objective lens (12), and the focus drive coil (13a) and the tracking drive coils (13b, 13c) are put in an open magnetic field produced by a magnetic yoke (14) having permanent magnets (15a, 15b), which makes magnetic flux to cross the coils, thereby to drive the objective lens (12); thus the size of the unit is decreased and made light, and further, the weight of the moving part is made light, to boost sensitivity thereby.

    摘要翻译： 在物镜驱动单元中，物镜（12）被固定到线圈架（11）上，线圈架（11）具有绕其轴线与物镜（12）的轴线同轴的聚焦驱动线圈（13a），并且跟踪 卷绕在其上的潜线圈（13b，13c）的轴线与物镜（12）的轴线垂直，并且聚焦驱动线圈（13a）和跟踪驱动线圈（13b，13c）被置于产生的开放磁场中 通过具有永磁体（15a，15b）的磁轭（14）使磁通量与线圈交叉，从而驱动物镜（12）; 因此单元的尺寸减小并变轻，并且进一步使移动部件的重量变轻，从而提高灵敏度。

    Pickup cartridge and mounting device therefor
    59.
    发明授权
    Pickup cartridge and mounting device therefor 失效
    拾取盒及其安装装置

    公开(公告)号：US4276635A

    公开(公告)日：1981-06-30

    申请号：US123494

    申请日：1980-02-21

    申请人： Shuichi Obata ,  Masashi Ito

    发明人： Shuichi Obata ,  Masashi Ito

    IPC分类号： G11B3/42 ,  H04R23/02 ,  G11B3/02

    CPC分类号： G11B3/42

    摘要： A pickup cartridge and a pickup cartridge mounting device therefor wherein a plug protrusion of tetragonal sectional area is formed at the rear end of a pickup cartridge, a recess of tetragonal sectional area with at least three walls for receiving the plug protrusion is formed at the front end of a tone arm or the like, and after the plug protrusion is inserted into the recess, the protrusion is strongly clamped between two walls of the recess by a mounting screw. Thus, replacement of pickup cartridges is made easy and reliable.

    摘要翻译： 一种拾取盒和拾取盒安装装置，其中在拾取盒的后端处形成四边形截面积的插头突起，在前部形成有至少三个用于接收插头突起的壁的四边形截面积的凹部 调音臂等的端部，并且在插头突出部插入到凹部中之后，通过安装螺钉将突起牢固地夹在凹部的两个壁之间。 因此，拾取盒的更换变得容易和可靠。