公开(公告)号：US20090298804A1

公开(公告)日：2009-12-03

申请号：US12294267

申请日：2007-03-30

申请人： Sabine Gaisser ,  Christine Martin ,  Ming Zhang ,  Barrie Wilkinson ,  Nigel Coates ,  Mohammed Nur-E-Alam ,  Nikolaos Galtatzis

发明人： Sabine Gaisser ,  Christine Martin ,  Ming Zhang ,  Barrie Wilkinson ,  Nigel Coates ,  Mohammed Nur-E-Alam ,  Nikolaos Galtatzis

IPC分类号： A61K31/33 ,  C07D225/06 ,  C12P17/10 ,  C12N1/21

CPC分类号： C07D225/06

摘要： The present invention relates to 15-desmethoxymacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies.

摘要翻译： 本发明涉及15-脱甲氧基锍类似物，其可用于，例如， 在治疗癌症，B细胞恶性疟疾，真菌感染，中枢神经系统疾病和神经变性疾病，依赖于血管生成的疾病，自身免疫疾病和/或作为癌症的预防性预处理。 本发明还提供了这些化合物的制备方法及其在医药中的用途，特别是用于治疗和/或预防癌症或B细胞恶性肿瘤的方法。

公开(公告)号：US07626962B1

公开(公告)日：2009-12-01

申请号：US11560418

申请日：2006-11-16

申请人： Ming Zhang ,  Jun Shen

发明人： Ming Zhang ,  Jun Shen

IPC分类号： H04W4/00

CPC分类号： H04W8/245 ,  H04M1/72547 ,  H04W4/06

摘要： Taught herein are devices, systems, and methods for creating, procuring, and maintaining a priority scheme for cell broadcast messages. In an exemplary embodiment, the priority scheme includes a plurality of cell broadcast channels (CBCH) that are assigned logic groups, which in turn are assigned a priority level. Accordingly, cell broadcast (CB) messages with higher priority levels are displayed first on the receiving device.

摘要翻译： 这里介绍的是用于创建，采购和维护小区广播消息优先级方案的设备，系统和方法。 在示例性实施例中，优先级方案包括被分配逻辑组的多个小区广播信道（CBCH），这又被分配优先级。 因此，首先在接收装置上显示具有较高优先级的小区广播（CB）消息。

公开(公告)号：US20090209507A1

公开(公告)日：2009-08-20

申请号：US12294253

申请日：2007-03-30

申请人： Sabine Gaisser ,  Christine Martin ,  Ming Zhang ,  Barrie Wilkinson ,  Nigel Coates ,  Mohammed Nur-E-Alam ,  William Vousden

发明人： Sabine Gaisser ,  Christine Martin ,  Ming Zhang ,  Barrie Wilkinson ,  Nigel Coates ,  Mohammed Nur-E-Alam ,  William Vousden

IPC分类号： A61K31/395 ,  C07D225/06 ,  A61P35/00 ,  C12P17/10 ,  C12N5/10

CPC分类号： C07D225/06

摘要： The present invention relates to 15-O-desmethylmacbecin analogues according to the formula (IA) or (IB) herein, or a pharmaceutically acceptable salt thereof: wherein: R1 and R2 either both represent H or together they represent a bond (i.e. C4 to C5 is a double bond); and R3 represents H or CONH2 that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies.

摘要翻译： 本发明涉及根据本文的式（IA）或（IB）的15-O-去甲基蒿酸类似物或其药学上可接受的盐：其中：R 1和R 2都表示H或一起表示一个键（即C 4至 C5是双键）; 并且R 3表示可用的H或CONH 2，例如。 在治疗癌症，B细胞恶性肿瘤，疟疾，真菌感染，中枢神经系统疾病和神经变性疾病，依赖于血管生成的疾病，自身免疫疾病和/或作为癌症的预防性预处理。 本发明还提供了这些化合物的制备方法及其在医药中的用途，特别是用于治疗和/或预防癌症或B细胞恶性肿瘤的方法。

公开(公告)号：US20090092124A1

公开(公告)日：2009-04-09

申请号：US11866811

申请日：2007-10-03

申请人： Sandeep Kishan Singhal ,  Peter Bernard Key ,  Ming Zhang ,  Guobin Shen ,  Thomas Karagiannis ,  Ayalvadi Jagannathan Ganesh

发明人： Sandeep Kishan Singhal ,  Peter Bernard Key ,  Ming Zhang ,  Guobin Shen ,  Thomas Karagiannis ,  Ayalvadi Jagannathan Ganesh

IPC分类号： H04L12/28

CPC分类号： H04L67/104 ,  H04L67/1065 ,  H04L67/1072 ,  H04L67/327

摘要： Using location-independent names to identify content, a service for mapping endpoint requests to requested content. Content requested by an endpoint of the network is mapped to a dynamic “swarm” of server, peer, or other endpoints capable of supporting the content download. Content names are mapped to a dynamically generated content swarm, presenting a current set of hosts, which can provide the requested content. Optionally, varying degrees of explicit visibility into routing paths and the performance tradeoffs between those routing paths is supported. Based on a set of class of service parameters for a given request for content, a host can initiate route selection based on class of service parameters, predicated on routing metrics maintained by the network by cooperating endpoints and/or network routers.

摘要翻译： 使用与位置无关的名称来标识内容，将端点请求映射到请求的内容的服务。 由网络的端点请求的内容被映射到能够支持内容下载的服务器，对等端或其他端点的动态“群”。 内容名称被映射到动态生成的内容群，呈现当前的一组主机，可以提供所请求的内容。 可选地，支持对路由路径的不同程度的显式可见性以及这些路由路径之间的性能折衷。 基于针对内容的给定请求的一组服务参数类型，主机可以基于服务类别参数来启动路由选择，基于由协作端点和/或网络路由器由网络维护的路由度量。

公开(公告)号：US20090086640A1

公开(公告)日：2009-04-02

申请号：US11865914

申请日：2007-10-02

申请人： Ming Zhang ,  Ratul Mahajan ,  Lindsey Philip Poole ,  Vivek Sadananda Pai

发明人： Ming Zhang ,  Ratul Mahajan ,  Lindsey Philip Poole ,  Vivek Sadananda Pai

IPC分类号： H04L12/66

CPC分类号： H04L12/5692 ,  H04L47/70

摘要： The claimed subject matter provides systems and/or methods that discover comparative differences in performance of Internet Service Provider networks. The system can include devices, components, and/or processes that partitions measurement processes into cycles and measures at least one Internet Service Provider network every cycle, develops and distributes to interrogation nodes a list of destination Internet Protocol (IP) addresses to interrogate, and utilizes results delivered or retrieved from interrogation nodes to generate a report on the comparative performance of Internet Service Provider networks queried.

摘要翻译： 所要求保护的主题提供发现互联网服务提供商网络的性能的比较差异的系统和/或方法。 该系统可以包括将测量过程分为周期的设备，组件和/或过程，并且每周期至少测量一个因特网服务提供商网络，开发并向询问节点分发要查询的目的地互联网协议（IP）地址的列表，以及 利用从询问节点传送或检索的结果生成关于所查询的互联网服务提供商网络的比较性能的报告。

公开(公告)号：US20090014684A1

公开(公告)日：2009-01-15

申请号：US11993574

申请日：2006-06-22

申请人： Ming Zhang ,  Li Zhang ,  Xiaolei Zhang ,  Qiang Zhang

发明人： Ming Zhang ,  Li Zhang ,  Xiaolei Zhang ,  Qiang Zhang

IPC分类号： C09K11/78

CPC分类号： C09K11/7796 ,  C04B35/447 ,  C04B2235/3201 ,  C04B2235/3206 ,  C04B2235/3208 ,  C04B2235/3213 ,  C04B2235/3215 ,  C04B2235/3217 ,  C04B2235/3224 ,  C04B2235/3225 ,  C04B2235/3227 ,  C04B2235/3229 ,  C04B2235/3262 ,  C04B2235/3284 ,  C04B2235/3409 ,  C04B2235/3418 ,  C04B2235/446 ,  C04B2235/9661 ,  C04B2235/9669 ,  C09K11/7778

摘要： The present invention provides a new ultra-long after-glow phosphorescent material and manufacturing method for the same. The said materials include a phosphor including aMS.bM3(PO4)2.cMSiO2.dMO.fAl2O3.xRO.yTR2O3.zMnO, where the M is Ca, Mg, Ba, Sr, Zn or combinations thereof, The R is Eu, Sm, Yb, Pr and Nd or combinations thereof; the TR is La, Y, Nd, Dy, Er, Tu, Ce, Ho or combinations thereof; and a, b, c, d, f x, y, z is the number of mol. The phosphorescent material has superior water resistance and temperature resistance.

摘要翻译： 本发明提供了一种新的超长余辉发磷光材料及其制造方法。 所述材料包括包含MS.bM3（PO4）2·cMiO·dMO·fAl2O3.xRO.yTR2O3.zMnO的荧光体，其中M为Ca，Mg，Ba，Sr，Zn或其组合，R为Eu，Sm ，Yb，Pr和Nd或其组合; TR是La，Y，Nd，Dy，Er，Tu，Ce，Ho或其组合; 和a，b，c，d，f x，y，z是摩尔数。 磷光材料具有优异的耐水性和耐温性。

公开(公告)号：US20080317259A1

公开(公告)日：2008-12-25

申请号：US11620573

申请日：2007-01-05

申请人： Ming Zhang ,  Xiaoyan Lu

发明人： Ming Zhang ,  Xiaoyan Lu

IPC分类号： H04R3/00 ,  H04B15/00

CPC分类号： H04R3/005 ,  G10L15/04 ,  G10L25/78

摘要： A small array microphone system includes an array microphone having a plurality of microphones and operative to provide a plurality of received signals, each microphone providing one received signal. A first voice activity detector (VAD) provides a first voice detection signal generated using the plurality of received signals to indicate the presence or absence of in-beam desired speech. A second VAD provides a second voice detection signal generated using the plurality of received signals to indicate the presence or absence of out-of-beam noise when in-beam desired speech is absent. A reference signal generator provides a reference signal based on the first voice detection signal, the plurality of received signals, and a beamformed signal, wherein the reference signal has the desired speech suppressed. A beamformer provides the beamformed signal based on the second voice detection signal, the reference signal, and the plurality of received signals, wherein the beamformed signal has noise suppressed. A multi-channel noise suppressor operative to further suppress noise in the beamformed signal and provide an output signal. A speech reliability detector provides a reliability detection signal indicating the reliability of each frequency subband. The first voice detection signal, the second voice detection signal, the reliability detection signal and the output signal are provided to the speech recognition engine.

摘要翻译： 小阵列麦克风系统包括具有多个麦克风并且可操作以提供多个接收信号的阵列麦克风，每个麦克风提供一个接收的信号。 第一语音活动检测器（VAD）提供使用多个接收信号产生的第一语音检测信号，以指示波束内期望语音的存在或不存在。 第二VAD提供使用多个接收信号产生的第二语音检测信号，以在不存在束内期望语音时指示出射外噪声的存在或不存在。 参考信号发生器基于第一语音检测信号，多个接收信号和波束形成信号提供参考信号，其中参考信号具有所需的语音抑制。 波束形成器基于第二语音检测信号，参考信号和多个接收信号提供波束形成信号，其中波束形成的信号被抑制噪声。 一种多声道噪声抑制器，用于进一步抑制波束形成信号中的噪声并提供输出信号。 语音可靠性检测器提供表示每个频率子带的可靠性的可靠性检测信号。 第一语音检测信号，第二语音检测信号，可靠性检测信号和输出信号被提供给语音识别引擎。

公开(公告)号：US20080247584A1

公开(公告)日：2008-10-09

申请号：US11696325

申请日：2007-04-04

申请人： Ming Zhang ,  Wan-Chieh Pai

发明人： Ming Zhang ,  Wan-Chieh Pai

IPC分类号： H04R19/04

CPC分类号： H04R3/005 ,  H04M1/035 ,  H04M1/19

摘要： An electronic device includes a case and a microphone array. The case includes a front surface, a rear surface, and side edges connecting the front surface and the rear surface. The microphone array includes a first microphone module and a second microphone module disposed in the case and arranged in a row not parallel to the side edges of the case.

摘要翻译： 电子设备包括壳体和麦克风阵列。 壳体包括前表面，后表面和连接前表面和后表面的侧边缘。 麦克风阵列包括第一麦克风模块和设置在壳体中并且布置成不平行于壳体的侧边缘的行的第二麦克风模块。

公开(公告)号：US07415294B1

公开(公告)日：2008-08-19

申请号：US11103729

申请日：2005-04-11

申请人： Ming Zhang ,  Yen-Son Paul Huang

发明人： Ming Zhang ,  Yen-Son Paul Huang

IPC分类号： H04M1/00

CPC分类号： H04M1/0258 ,  H04M1/6041 ,  H04M1/6066

摘要： A hands-free voice communication apparatus with integrated speakerphone and earpiece is described. The speakerphone includes a loudspeaker and zero, one or multiple microphones. The earpiece includes a small loudspeaker, one or more microphones, a wireless module, and a digital signal processing (DSP) module. The hands-free device support hands-free voice communication via the speakerphone or the earpiece. The earpiece is functional when removed from the speakerphone case and may be used for voice communication with privacy. When the earpiece is placed back in the speakerphone case, the speakerphone is functional and may be used for voice communication with convenience. The DSP module performs digital signal processing for both the earpiece and the speakerphone, e.g., using different sets of parameters. The speakerphone may be a standalone device or may be part of a communication device. The wireless module communicates with the communication device, which provide end-to-end communication with a far-end user.

摘要翻译： 描述了具有集成扬声器和耳机的免提语音通信装置。 扬声器包括扬声器和零个，一个或多个麦克风。 听筒包括一个小型扬声器，一个或多个麦克风，无线模块和数字信号处理（DSP）模块。 免提设备通过扬声器或耳机支持免提语音通信。 从扬声器外壳中取出时，耳机功能正常，可用于隐私的语音通信。 当耳机放回扬声器外壳时，扬声器功能正常，可方便地用于语音通信。 DSP模块对耳机和扬声器电话进行数字信号处理，例如使用不同的参数组。 扬声器可以是独立设备，也可以是通信设备的一部分。 无线模块与通信设备通信，该通信设备提供与远端用户的端到端通信。

公开(公告)号：US20080147393A1

公开(公告)日：2008-06-19

申请号：US11611185

申请日：2006-12-15

申请人： Ming Zhang ,  Xiaoyan Lu

发明人： Ming Zhang ,  Xiaoyan Lu

IPC分类号： G10L15/20

CPC分类号： G10L21/0208 ,  G10L25/78

摘要： The invention provides an Internet communication device. The Internet communication device plays a remote audio signal received via a network and transmits an audio signal back to the remote party to complete the communication. The Internet communication device comprises a line-in speech detection module and a line-in channel control module. The line-in speech detection module detects whether the remote audio signal is speech or not to generate a remote speech detection result. The line-in channel control module then attenuates the remote audio signal if the remote speech detection result indicates that the remote audio signal is not speech, thus, all noise including non-stationary noise is removed from the remote audio signal.

摘要翻译： 本发明提供一种因特网通信设备。 互联网通信设备播放通过网络接收到的远程音频信号，并将音频信号发送回对方以完成通信。 互联网通信设备包括线路输入语音检测模块和线路输入信道控制模块。 线路输入语音检测模块检测远程音频信号是否是语音，以产生远程语音检测结果。 如果远程语音检测结果指示远程音频信号不是语音，则线路输入信道控制模块会衰减远程音频信号，从而从远程音频信号中去除包括非平稳噪声的所有噪声。