摘要:
A water removal device to withdraw virtually all the water from the drain in the bottom of a swimming pool comprising an elongated lower suction or vacuum housing including a plurality of perforations or holes formed therein to receive water from a pool drain and an upper suction or vacuum source to create a suction or vacuum to draw water from the pool drain through the perforations or holes into and through the lower suction or vacuum housing to remove the water from the pool drain.
摘要:
In a riding mower having a frame, a mower deck supported beneath the frame, a chair on said frame and a source of motive power also supported on said frame. The frame is supported on forward and rear wheel assemblies, and the wheel assemblies each have a supporting wheel, each wheel assembly having a vibration damping system interposed between the frame and each wheel assembly. The vibration damping system comprising at least one pillow interposed between the frame and each wheel assembly and each pillow being of a resilient material for absorbing shock and vibration resulting from a wheel contacting irregularities in the terrain traversed thereby.
摘要:
An improved sleeve bearing for locomotive traction motor that provides additional lubrication over and above that of the one central wick currently used. The sleeve bearing is provided with a recirculation system comprised of either at least two additional wicks located near the 6:00 operating location or multiple oil communication and delivery grooves passageways communicating with the oil flinger grooves placed for the purpose of collecting and providing a mechanism for providing additional lubrication for extending the oil-wetted envelope available for supporting the truck-axle journal in the axial direction.
摘要:
This invention provides modified rapamycins that have specific monosaccharide(s), oligosaccharide(s), pseudosugar(s) or derivatives thereof attached through a linker to create rapamycin carbohydrate derivatives having enhanced pharmacokinetic and/or pharmacodynamic profiles. For example, administration of the rapamycin carbohydrate derivative results in altered pharmacokinetic profiles and reduced toxicities. Thus, the present invention provides compounds with characteristics that are distinct from other drugs in its class such as rapamycin.
摘要:
Stable concentrated suspensions readily dispersible in water comprising one or more agricultural solids, a single non-ionic surfactant and a water-soluble glycol liquid. The agricultural solids include fertilizers, adjuvants, herbicides, pesticides and combinations thereof approved for use with foods. The non-ionic surfactant is an alkyl-phenoxy-poly(ethylenoxide)alkanol, an ethoxylated aliphatic C11 to C15 alcohol, an ethylene oxide-propylene oxide block copolymer or an ethoxylated fatty acid. Preferably, the surfactant has an average molecular weight from about 300 to about 1000. The water-soluble glycol liquid is ethylene glycol, propylene glycol, or mixtures thereof. The agricultural solid particles are at least about 99 wt. % passable through a Tyler #48 sieve. The suspensions of the invention exhibit physical stability during normal storage conditions, good pourability, and are readily dispersed in water.
摘要:
The present invention relates to thiazolylpiperidine derivatives of the general formula (I): in which: A represents a radical chosen from the radicals a1 and a2 below: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3 below: and R1, R2, R2′, R3, R4, R5, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.
摘要:
A method and a system for determining taxes attributable to a financial transaction create a tax rate table, link an entity of the financial transaction to the tax rate table through a product rule, and calculate taxes based on the tax rate table according to one component of the financial transaction. The tax rate tables can be linked by a default product rule, which is a defined by a global variable. Alternatively, specific product rules can be used to link specific entities, such as tax jurisdiction records, or legal entity records. In one application, the method and the system calculate revenue tax, cost tax, input tax, and profits for each transaction. The method and the system may further include multi-currency support analysis for a financial transaction so that a financial transaction can be analyzed under a common currency, even though the financial transaction is conducted using one or more currencies in one or more jurisdictions.
摘要:
A composition and method for treatment and/or prophylaxis of stressed-induced conditions and a method of forming the composition are disclosed. The composition includes hyaluronic acid and superoxide dismutase configured to mitigate denaturing of the superoxide dismutase in a digestive track of an animal. Mitigating the denaturing of the superoxide dismutase allows simultaneous administration of both the hyaluronic acid and superoxide dismutase to the circulatory and lymph systems of an animal.
摘要:
The invention is directed to isomeric mixtures of cyclosporine analogues that are structurally similar to cyclosporine A. The mixtures possess enhanced efficacy and reduced toxicity over the individual isomers and over naturally occurring and other presently known cyclosporines and cyclosporine derivatives. Embodiments of the present invention are directed toward cis and trans-isomers of cyclosporin A analogs referred to as ISATX247, and derivatives thereof. Mixtures of ISATX247 isomers exhibit a combination of enhanced potency and reduced toxicity over the naturally occurring and presently known cyclosporins. ISATX247 isomers and alkylated, arylated, and deuterated derivatives are synthesized by stereoselective pathways where the particular conditions of a reaction determine the degree of siereoselectivity. The ratio of isomers in a mixture may range from about 10 to 90 percent by weight of the (E)-isomer to about 90 to 10 percent by weight of the (Z)-isomer, based on the total weight of the mixture.