公开(公告)号：US20060270694A1

公开(公告)日：2006-11-30

申请号：US11416652

申请日：2006-05-02

申请人： Brian Wong

发明人： Brian Wong

IPC分类号： A61K31/506 ,  A61K31/505

CPC分类号： A61K31/506 ,  A61K31/505 ,  A61K45/06 ,  A61K2300/00

摘要： The present disclosure provides 2,4-pyrimidinediamine compounds that selectively inhibit JAK kinase as compared to Syk kinase and various methods of using the JAK-selective compounds.

摘要翻译： 本公开提供了与Syk激酶相比选择性抑制JAK激酶的2,4-嘧啶二胺化合物和使用JAK选择性化合物的各种方法。

公开(公告)号：US07133883B2

公开(公告)日：2006-11-07

申请号：US10329077

申请日：2002-12-23

申请人： Nisha D. Talagala ,  Brian Wong

发明人： Nisha D. Talagala ,  Brian Wong

IPC分类号： G06F17/30 ,  G06F12/00

CPC分类号： G06F17/30958 ,  Y10S707/99953

摘要： Diagnosis of corruption in interrelated data entities uses a graph of nodes and edges. Datum nodes represent the data entities, relationship nodes represent the relationships among the data entities. The datum nodes are connected through their relationship nodes by the edges. When corruption is detected, the relationships are analyzed and each edge connecting a datum node to a relationship node is removed from the graph when the corresponding relationship is invalid. The datum nodes that remain connected to their relationship nodes form a subgraph and the corresponding data entities are considered correct. In one aspect, if more than one subgraph is formed, the datum nodes in the largest are used. In another aspect, the data entities and relationships are analyzed to create the graph when the data entities are assumed correct. The data entities may be data and metadata of various types that can be associated with the data.

摘要翻译： 相关数据实体中的腐败诊断使用节点和边的图。 基准节点表示数据实体，关系节点表示数据实体之间的关系。 基准节点通过其关系节点通过边缘连接。 当检测到损坏时，分析关系，并且当对应关系无效时，从图中删除将数据节点连接到关系节点的每个边缘。 保持连接到它们的关系节点的基准节点形成子图，并且相应的数据实体被认为是正确的。 在一个方面，如果形成多于一个子图，则使用最大的基准点。 在另一方面，当数据实体被假定为正确时，分析数据实体和关系以创建图。 数据实体可以是可以与数据相关联的各种类型的数据和元数据。

公开(公告)号：US20060248513A1

公开(公告)日：2006-11-02

申请号：US11116077

申请日：2005-04-27

申请人： Gavin Foster ,  Randy Johnson ,  James Kenley ,  Tedrick Northway ,  Neil O'Connor ,  Brian Wong ,  Clea Zolotow

发明人： Gavin Foster ,  Randy Johnson ,  James Kenley ,  Tedrick Northway ,  Neil O'Connor ,  Brian Wong ,  Clea Zolotow

IPC分类号： G06F9/44

CPC分类号： G06F9/445 ,  G06F8/60

摘要： The invention is a system for installing a new operating system on a logical partition that has no existing software or data. The system comprises a baseline code and a process for customizing and configuring the baseline code for use in an on-demand environment. The process for customizing and configuring the baseline code comprises establishing a plurality of datasets that allow users to access the operating system after installation. The critical datasets that produce an operable system include virtual telecommunications parameters, job entry system parameters, operating system parameters, and security parameters.

摘要翻译： 本发明是一种在没有现有软件或数据的逻辑分区上安装新的操作系统的系统。 该系统包括基准代码和用于定制和配置基准代码以在按需环境中使用的过程。 定制和配置基准代码的过程包括建立多个数据集，允许用户在安装后访问操作系统。 产生可操作系统的关键数据集包括虚拟电信参数，作业输入系统参数，操作系统参数和安全参数。

公开(公告)号：US20060199218A1

公开(公告)日：2006-09-07

申请号：US11431577

申请日：2006-05-09

申请人： Brian Wong ,  Chong Fu ,  Helena Mancebo ,  Xiulan Zhou

发明人： Brian Wong ,  Chong Fu ,  Helena Mancebo ,  Xiulan Zhou

IPC分类号： C12Q1/68 ,  G01N33/567 ,  G01N33/53

CPC分类号： G01N33/9493 ,  G01N33/5047 ,  G01N33/505 ,  G01N33/5052

摘要： The present invention provides compositions and methods for modulating leukocyte activation. Nucleic acids encoding proteins and proteins so encoded which are capable of modulating leukocyte activation are provided. Compositions and methods for the treatment of disorders related to leukocyte dysfunction or dysregulation are also provided. Prophylactics and methods for the prevention of such disorders are also provided. Also provided are compositions and methods for diagnostic and prognostic determination of such disorders. Further provided are assays for the identification of bioactive agents capable of modulating leukocyte activation.

公开(公告)号：US07063960B2

公开(公告)日：2006-06-20

申请号：US09873829

申请日：2002-05-09

申请人： Yongwon Choi ,  Brian Wong

发明人： Yongwon Choi ,  Brian Wong

IPC分类号： C07K1/00 ,  C07K14/00 ,  C07K14/01 ,  C12P21/02 ,  C07H21/00

CPC分类号： C07K16/2875 ,  A61K38/00 ,  A61K39/00 ,  A61K48/00 ,  C07K14/525 ,  C07K14/70575 ,  C07K2317/76 ,  C07K2319/30 ,  C12N15/1096

摘要： A method of modulating immune response in an animal is disclosed. Such a method comprises: interacting the immature dendritic cells from the animal with an antigen ex vivo so that the immature dendritic cells present the antigen on their surfaces, inducing maturation of the immature dendritic cells ex vivo, and contacting the mature dendritic cells ex vivo with a modulator comprising TRANCE, conservative variants thereof, fragments thereof, analogs or derivatives thereof, or a fusion protein comprising the amino acid sequence of TRANCE, conservative variants thereof, or fragments thereof. After contacting the modulator ex vivo, the mature dendritic cells are introduced into the animal. As a result, immune response in the animal towards the antigen is modulated relative to the immune response against the antigen in an animal in which dendritic cells did not interact with the antigen ex vivo, and did not contact a modulator ex vivo. Preferably, the method of the present invention results in increasing immune response towards the antigen in the animal.

摘要翻译： 公开了调节动物免疫应答的方法。 这样的方法包括：使来自动物的未成熟树突状细胞与抗原离体相互作用，使得未成熟树突细胞在其表面上存在抗原，诱导未成熟树突状细胞离体成熟，并使成熟树突状细胞离体与 包含TRANCE，其保守变体，其片段，其类似物或衍生物或包含TRANCE的氨基酸序列，其保守变体或其片段的融合蛋白的调节剂。 离体调节剂离体接触后，将成熟树突状细胞导入动物体内。 因此，动物中针对抗原的免疫反应相对于动物中针对抗原的免疫应答进行调节，其中树突细胞离体不与抗原相互作用，并且不离体接触调节剂。 优选地，本发明的方法导致对动物中抗原的免疫应答增加。

公开(公告)号：US07045308B2

公开(公告)日：2006-05-16

申请号：US10112674

申请日：2002-03-29

申请人： Brian Wong ,  Chong Alan Fu ,  Helena Mancebo ,  Xiulan X.Z. Zhou

发明人： Brian Wong ,  Chong Alan Fu ,  Helena Mancebo ,  Xiulan X.Z. Zhou

IPC分类号： C12N15/12 ,  C12N15/63 ,  C12N15/00 ,  G01N33/53

CPC分类号： G01N33/9493 ,  G01N33/5047 ,  G01N33/505 ,  G01N33/5052

摘要： The present invention provides compositions and methods for modulating leukocyte activation. Nucleic acids encoding proteins and proteins so encoded which are capable of modulating leukocyte activation are provided. Compositions and methods for the treatment of disorders related to leukocyte dysfunction or dysregulation are also provided. Prophylactics and methods for the prevention of such disorders are also provided. Also provided are compositions and methods for diagnostic and prognostic determination of such disorders. Further provided are assays for the identification of bioactive agents capable of modulating leukocyte activation.

公开(公告)号：US20050190786A1

公开(公告)日：2005-09-01

申请号：US11064761

申请日：2005-02-22

申请人： Vincent Jones ,  Partho Mishra ,  Geert Awater ,  D.J. van Nee ,  Arnold Liu ,  Brian Wong

发明人： Vincent Jones ,  Partho Mishra ,  Geert Awater ,  D.J. van Nee ,  Arnold Liu ,  Brian Wong

IPC分类号： H04B7/00 ,  H04J3/16 ,  H04J3/22 ,  H04J3/24 ,  H04L1/00 ,  H04L12/28 ,  H04L12/56

CPC分类号： H04L1/0045 ,  H04W24/00 ,  H04W28/16 ,  H04W88/02

摘要： In a packet detector, one or more tests are performed for packet detection according to packet detection parameters associated with the one or more tests, a rate of false detection is measured, and the packet detection parameters are adjusted accordingly to reduce the rate of false detection. The rate of false detection might be determined by analyzing post-detection and processing of a signal deemed to be a signal representing a packet for a failure of decoding indicative of a false detection. Such analysis might include testing for a failed SFD search, training symbol anomalies, poor conditioning of metrics used to determine frequency offset and OFDM timing, incorrect data fields, or the like.

摘要翻译： 在分组检测器中，根据与一个或多个测试相关联的分组检测参数，对分组检测执行一个或多个测试，测量错误检测率，并相应地调整分组检测参数以降低错误检测率 。 可以通过分析被认为是表示用于指示错误检测的解码失败的分组的信号的信号的后检测和处理来确定错误检测的速率。 这种分析可能包括测试失败的SFD搜索，训练符号异常，用于确定频率偏移和OFDM定时的度量的不良调节，不正确的数据字段等。

公开(公告)号：US20050115873A1

公开(公告)日：2005-06-02

申请号：US10725035

申请日：2003-12-02

申请人： Pierre de Villers ,  Wes Jamroz ,  Denis Lafrance ,  Brian Wong

发明人： Pierre de Villers ,  Wes Jamroz ,  Denis Lafrance ,  Brian Wong

IPC分类号： G01N21/35 ,  G01N25/08 ,  G06K9/62

CPC分类号： G01N21/3554 ,  G01N21/3559 ,  G01N25/08

摘要： A method and apparatus for non-contact determination of liquid concentrations such as the content of water, oil, dye, paint, fuel, glue, etc., in a moving or stationary mass of production such as wood, paper, powders, fabrics, sand, bricks, concrete, plants, and the like, or in other liquids such as oil spills in water, is provided. The method comprises measuring the passive emissivity of a substance, using an imaging radiometer. It has been found that an emissivity image may be used to quantify the liquid content in a substance. The invented method allows for non-contact, rapid and continuous in-line measurements.

摘要翻译： 用于在诸如木材，纸张，粉末，织物等的移动或静止的生产物质中非接触地测定液体浓度如水，油，染料，油漆，燃料，胶水等的含量的方法和装置， 砂，砖，混凝土，植物等，或者在其他液体中，例如溢油在水中。 该方法包括使用成像辐射计测量物质的被动发射率。 已经发现，发射率图像可以用于量化物质中的液体含量。 本发明的方法允许非接触，快速和连续的在线测量。

公开(公告)号：US20190268987A1

公开(公告)日：2019-08-29

申请号：US15907957

申请日：2018-02-28

申请人： Andrew Schuyler ,  Chad Recore ,  Gaetano Ling ,  Elger Oberwelz ,  Courtney Song ,  Tobias Toft ,  Aaron Wansch ,  Brian Wong ,  Joseph Fledderman

发明人： Andrew Schuyler ,  Chad Recore ,  Gaetano Ling ,  Elger Oberwelz ,  Courtney Song ,  Tobias Toft ,  Aaron Wansch ,  Brian Wong ,  Joseph Fledderman

IPC分类号： H05B33/08

摘要： Embodiments of the present invention include a lighting fixture(s), a computer program product and a computer-implemented method that include program code executed by a processor(s) that obtains a request to implement a specified lighting pattern in the lighting fixture(s). Each lighting fixture includes effect lighting communicatively coupled to the processor(s) and functional lighting (oriented to illuminate a surface below the lighting fixture) communicatively coupled to the processor(s). The program code identifies the specified lighting pattern in a memory communicatively coupled to the processor(s), which includes a sequence for illuminating a portion of the effect lighting elements. The processor(s) executes the specified lighting pattern in the lighting fixture(s).

公开(公告)号：US08903577B2

公开(公告)日：2014-12-02

申请号：US12609545

申请日：2009-10-30

申请人： Bassam D. Jalbout ,  Brian Wong

发明人： Bassam D. Jalbout ,  Brian Wong

IPC分类号： B60L11/00 ,  B60W10/04 ,  B60K28/16 ,  B60L15/08 ,  B60L15/20

CPC分类号： B60W10/08 ,  B60K28/16 ,  B60L11/00 ,  B60L15/08 ,  B60L15/2045 ,  B60L15/2072 ,  B60L2200/26 ,  B60W2520/26 ,  B60W2550/148 ,  Y02T10/645 ,  Y02T10/646 ,  Y02T10/7283

摘要： Fixed frequency, fixed duration pulse streams are used to control power switches for one or more electrical motors of electrically powered vehicles or hybrid vehicles having one or more electric motors. The advantages of a pulse system are increased power efficiency and system simplicity over analog systems. The capability of system calibration with a single pulse allows the system to be used under any conditions, and real time adaptation to changes in conditions. Such system and methods provide much improved acceleration over other electrical systems, by making the best use of the coefficient of starting or static friction. The systems and methods provide a non slip traction control system, and the use of an off state in the pulse stream is superior to the use of braking systems for the same purpose, which waste power and cause mechanical wear. In addition, related computer program products are described.

摘要翻译： 固定频率固定持续时间脉冲流被用于控制具有一个或多个电动机的电动车辆或混合动力车辆的一个或多个电动机的电力开关。 脉冲系统的优点是提高了模拟系统的功率效率和系统简单性。 使用单个脉冲进行系统校准的能力允许系统在任何条件下使用，并实时适应条件变化。 这种系统和方法通过充分利用起动或静摩擦系数提供比其他电气系统更大的改进的加速度。 这些系统和方法提供了非滑动牵引力控制系统，并且在脉冲流中使用关闭状态优于使用相同目的的制动系统，其浪费功率并引起机械磨损。 此外，还描述了相关的计算机程序产品。