摘要:
The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis and cancer.
摘要:
Stiffened thin-walled natural fibre composite product having first fibre yarns (A), each first fibre having a first thickness, and second fibre yarns (B) having a second thickness larger than the first thickness. At least one side of said product is even. Applications for a seat post; a bicycle saddle; a bicycle frame; a bicycle handle bar; a baseball bat; a piece of furniture; a paddle; or a sheet for automotive applications.
摘要:
A pretensioning device (10) for a safety belt, of a motor vehicle, having a gas generator (17), a piston (21) guided in a tube (16), which closes a pressure area (20) in the tube (16) that is pressurized by the gas generator (17) whereupon the piston (21) is able to move in a pretensioning movement which is able to be conveyed to the safety belt by means of an inertia body (19a) resting on a front face (9) of the piston (21). The piston (21) forms a pass-through opening (1) releasable upon exceeding of a predetermined pressure and a recess (26) is provided in the front face (9) with an inertia body (19a) resting thereon, so that a flow connection is created from the pass-through opening (1) to the area (25) located behind the piston (21) in the direction of the pretensioning movement (S).
摘要:
The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.
摘要:
The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.
摘要:
An air dryer desiccant cartridge, the cartridge comprising a base having an inlet and an outlet, and a casing connected to the base to define a cavity there between, wherein the cavity contains a filter and a desiccant, the filter being arranged upstream of the desiccant such that during normal operation fluid flow entering the cartridge through the inlet passes through the filter and then on to the desiccant before reaching the outlet, and during purging of the cartridge purge flow entering the outlet passes through the desiccant before reaching the filter, wherein further the cartridge includes a valve operable to permit a portion of the purge flow to bypass the filter.
摘要:
The hydroxylated inorganic oxide support is functionalized by grafting at least one type of polyhydrosiloxane oil having from 10 to 200 siloxane units, the grafting being provided, on the one hand, by covalent bonds formed from a dehydrogenation/condensation reaction between Si-H groups of the polyhydrosiloxane oil and free hydroxyls of the hydroxylated support and, on the other hand, by hydrogen bonds between hydroxyls of the hydroxylated support and oxygen atoms of the polyhydrosiloxane oil, which exhibits free SiH groups.