-
51.发明申请POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY 有权具有控制释放速率和形态的POLY（ESTER AMIDE）-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY公开(公告)号：US20110200660A1
公开(公告)日：2011-08-18
申请号：US13037169
申请日：2011-02-28
申请人： Lothar Walter Kleiner , Jessica Reneé DesNoyer , Stephen Dirk Pacetti , Syed Faiyaz Ahmed Hossainy
发明人： Lothar Walter Kleiner , Jessica Reneé DesNoyer , Stephen Dirk Pacetti , Syed Faiyaz Ahmed Hossainy
IPC分类号： A61F2/82 , A61K9/00 , A61K38/44 , A61L33/06 , A61K31/573 , A61K31/566 , A61K31/506 , A61K31/436 , A61K31/45 , A61K31/337 , A61K47/34
CPC分类号： A61L27/34 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02
摘要： A method of forming a coating on a medical device having a controlled morphology is described. A medical device having a controlled morphology is described.
摘要翻译： 描述了在具有受控形态的医疗装置上形成涂层的方法。 描述具有受控形态的医疗装置。
-
公开(公告)号：US20110196187A1
公开(公告)日：2011-08-11
申请号：US12704092
申请日：2010-02-11
申请人： Florian Niklas Ludwig , Syed Faiyaz Ahmed Hossainy , Bjorn Svensson , Adam Sharkawy , Michael J. Cima , Omid C. Farokhzad , Jesus Magana , Randolf Von Oepen , Mina Chow , William E. Webler, JR. , Travis R. Yribarren , Kevin J. Ehrenreich
发明人： Florian Niklas Ludwig , Syed Faiyaz Ahmed Hossainy , Bjorn Svensson , Adam Sharkawy , Michael J. Cima , Omid C. Farokhzad , Jesus Magana , Randolf Von Oepen , Mina Chow , William E. Webler, JR. , Travis R. Yribarren , Kevin J. Ehrenreich
IPC分类号： A61N2/00
CPC分类号： A61N2/002
摘要： Apparatuses for delivering compositions of matter comprising a magnetically sensitive drug carrier and a related drug and methods for causing the drug carriers to localize within the patient using an internal or external magnetic field are described.
摘要翻译： 描述用于递送包含磁敏感药物载体和相关药物的物质组合物的装置和使用内部或外部磁场使药物载体定位在患者体内的方法。
-
53.发明授权Poly(ester amide)-based drug delivery systems with controlled release rate and morphology 有权具有控制释放速率和形态的基于聚（酯酰胺）的药物递送系统公开(公告)号：US07910152B2
公开(公告)日：2011-03-22
申请号：US11365549
申请日：2006-02-28
申请人： Lothar Walter Kleiner , Jessica Reneé DesNoyer , Stephen Dirk Pacetti , Syed Faiyaz Ahmed Hossainy
发明人： Lothar Walter Kleiner , Jessica Reneé DesNoyer , Stephen Dirk Pacetti , Syed Faiyaz Ahmed Hossainy
IPC分类号： B05D3/00
CPC分类号： A61L27/34 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02
摘要： A method of forming a coating on a medical device having a controlled morphology is described.
摘要翻译： 描述了在具有受控形态的医疗装置上形成涂层的方法。
-
54.发明申请Nanoparticle-Coated Medical Devices And Formulations For Treating Vascular Disease 审中-公开纳米颗粒涂层医疗器械和治疗血管疾病的配方公开(公告)号：US20100104653A1
公开(公告)日：2010-04-29
申请号：US12652697
申请日：2010-01-05
申请人： Florian Niklas Ludwig , Syed Faiyaz Ahmed Hossainy , Katsuyuki Murase , Li Zhao , Irina Astafieva
发明人： Florian Niklas Ludwig , Syed Faiyaz Ahmed Hossainy , Katsuyuki Murase , Li Zhao , Irina Astafieva
IPC分类号： A61K9/16
CPC分类号： A61L31/10 , A61K9/1075 , A61K9/127 , A61K9/51 , A61L31/16 , A61L2300/624 , A61L2300/626 , A61L2400/12
摘要： Nanoparticle-coated medical devices, nanoparticle-containing formulations and methods of using for treating a vascular disease are disclosed. The method for treating a vascular disease includes providing a formulation comprising a plurality of nanoparticles having a density different from that of blood and further comprising one or more bioactive agents encapsulated within, adhered to a surface of or integrated into the structure of the nanoparticles; and administering a therapeutically effective amount of the formulation to a vascular disease locale in a patient.
摘要翻译： 公开了纳米颗粒涂覆的医疗装置，含纳米颗粒的制剂和用于治疗血管疾病的方法。 用于治疗血管疾病的方法包括提供包含多个密度不同于血液的密度的纳米颗粒的制剂，并且进一步包含一种或多种包封在其内，附着于纳米颗粒的结构表面或整合到纳米颗粒结构中的生物活性剂; 以及将治疗有效量的制剂施用于患者的血管疾病区域。
-
公开(公告)号：US20090285874A1
公开(公告)日：2009-11-19
申请号：US12509222
申请日：2009-07-24
CPC分类号： A61L31/043 , A61L27/22 , A61L27/54 , A61L31/16 , A61L2300/25 , A61L2300/252 , A61L2300/416
摘要： Implantable devices (e.g., stent) having a protein patterning or bioactive patterning for accelerated healing and method of forming and using the same are provided.
摘要翻译： 提供了具有用于加速愈合的蛋白质图案化或生物活性图案化的可植入装置（例如，支架）及其形成和使用方法。
-
56.发明申请公开(公告)号：US20090240325A1
公开(公告)日：2009-09-24
申请号：US12052452
申请日：2008-03-20
申请人： Shaw Ling Hsu , Yiwen Tang , Lothar W. Kleiner , Fuh-Wei Tang , Ni Ding , Syed Faiyaz Ahmed Hossainy
发明人： Shaw Ling Hsu , Yiwen Tang , Lothar W. Kleiner , Fuh-Wei Tang , Ni Ding , Syed Faiyaz Ahmed Hossainy
CPC分类号： A61L27/34 , A61L31/10 , A61L2420/08 , C08L67/04
摘要： Implantable medical device coatings that have improved mechanical stability and medical devices coated with such coatings are disclosed.
摘要翻译： 公开了具有改善的机械稳定性的植入式医疗装置涂层和涂覆有这种涂层的医疗装置。
-
公开(公告)号：US20090005849A1
公开(公告)日：2009-01-01
申请号：US11726647
申请日：2007-03-21
申请人： Syed Faiyaz Ahmed Hossainy , Mikael Trollsas , Thierry Glauser , Yiwen Eveleen Tang , Eugene T. Michal
发明人： Syed Faiyaz Ahmed Hossainy , Mikael Trollsas , Thierry Glauser , Yiwen Eveleen Tang , Eugene T. Michal
IPC分类号： A61K31/337 , A61M25/10 , A61F2/82 , A61F2/84 , A61P9/00
CPC分类号： A61L31/043 , A61L2430/36
摘要： A method and apparatus to treat regions of a vessel is described. A protein elastin-based polymer is released from the apparatus to coat the vessel lining as a primary therapy or an adjunct therapy with the delivery and deployment of a stent with or without drug coating. The protein elastin-based polymer may include a triblock structure having an elastin pentapeptide as the flanking block and a hydrophilic variant of the pentapeptide as the middle block. Both the flanking and middle blocks can be modified to change the structural and chemical properties of the polymer. In particular, the protein elastin based polymer is adapted to perform at least one of controlling release of a treatment agent, stimulating endothelial cell growth and stabilizing the vulnerable plaque to prevent rupture of the vulnerable plaque.
摘要翻译： 描述了一种处理容器区域的方法和装置。 将蛋白质弹性蛋白基聚合物从装置中释放出来，作为主要疗法或辅助治疗来涂覆血管衬里，随着具有或不具有药物涂层的支架的递送和展开。 基于蛋白质弹性蛋白的聚合物可以包括具有弹性蛋白五肽作为侧翼嵌段的三嵌段结构和作为中间嵌段的五肽的亲水性变体。 可以改变侧面和中间嵌段以改变聚合物的结构和化学性质。 特别地，基于蛋白质弹性蛋白的聚合物适于执行控制治疗剂释放，刺激内皮细胞生长和稳定易损斑块中的至少一种，以防止脆弱斑块的破裂。
-
公开(公告)号：US20080160061A1
公开(公告)日：2008-07-03
申请号：US11303724
申请日：2005-12-16
IPC分类号： A61K38/44 , A61K38/18 , A61K31/56 , A61K31/4745 , A61K31/337 , A61F2/02
CPC分类号： A61L31/043 , A61L27/22 , A61L27/54 , A61L31/16 , A61L2300/25 , A61L2300/252 , A61L2300/416
摘要： Implantable devices (e.g., stent) having a protein patterning or bioactive patterning for accelerated healing and method of forming and using the same are provided.
摘要翻译： 提供了具有用于加速愈合的蛋白质图案化或生物活性图案化的可植入装置（例如，支架）及其形成和使用方法。
-
公开(公告)号：US20070282431A1
公开(公告)日：2007-12-06
申请号：US11443870
申请日：2006-05-30
申请人： David C. Gale , Yunbing Wang , Syed Faiyaz Ahmed Hossainy , Bin Huang , Garth L. Wilkes , Vincent J. Gueriguian
发明人： David C. Gale , Yunbing Wang , Syed Faiyaz Ahmed Hossainy , Bin Huang , Garth L. Wilkes , Vincent J. Gueriguian
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61L31/127 , A61L31/128 , A61L31/148 , B29C47/0007 , B29C47/0014 , B29C47/0021 , B29C47/0023 , Y10S977/753 , Y10S977/776 , Y10S977/831 , Y10S977/931
摘要： Methods and devices relating to polymer-bioceramic composite implantable medical devices are disclosed.
摘要翻译： 公开了与聚合物 - 生物陶瓷复合植入式医疗装置有关的方法和装置。
-
公开(公告)号：US06712845B2
公开(公告)日：2004-03-30
申请号：US09841798
申请日：2001-04-24
IPC分类号： A61F206
CPC分类号： A61L31/10 , A61L2400/18
摘要： A coating for a stent and methods for coating a stent are provided. The coating may be used for the sustained delivery of an active ingredient or a combination of active ingredients.
摘要翻译： 提供一种用于支架的涂层和用于涂覆支架的方法。 该涂层可用于持续递送活性成分或活性成分的组合。
-
-
-
-
-
-
-
-
-
搜索结果
118 条记录 (耗时 0.021 秒)
