公开(公告)号：US20050129672A1

公开(公告)日：2005-06-16

申请号：US10984406

申请日：2004-11-09

申请人： Steven Goldman ,  Takahiro Nakano

发明人： Steven Goldman ,  Takahiro Nakano

IPC分类号： A01K67/027 ,  A61K48/00 ,  C07H21/04 ,  C12N5/08 ,  C12N15/85 ,  C12N15/86

CPC分类号： C12N15/8509 ,  A01K67/0275 ,  A01K2217/05 ,  A01K2227/105 ,  C12N2830/008

摘要： The present invention relates to an enhancer which functions only in human brain and/or spinal cord motor neurons, where the enhancer comprises a nucleotide sequence of SEQ ID NO: 5, SEQ ID NO: 10, or SEQ ID NO: 16. The enhancer can be utilized as part of a nucleic acid construct which also has a nucleic acid encoding a marker protein or a therapeutic protein, a 3′ control region, and, optionally, a basal promoter, where these components are positioned with respect to one another to permit expression of the marker protein or the therapeutic protein. The enhancer of the present invention is useful in a method of isolating an enriched or purified population of motor neurons from a mixed population of human brain and/or spinal cells. In addition, the enhancer of the present invention can be used in a method of therapeutically targeting motor neurons.

摘要翻译： 本发明涉及仅在人脑和/或脊髓运动神经元中起作用的增强子，其中增强子包含SEQ ID NO：5，SEQ ID NO：10或SEQ ID NO：16的核苷酸序列。增强子 可以用作核酸构建体的一部分，其还具有编码标记蛋白或治疗性蛋白质的核酸，3'对照区域和任选的基础启动子，其中这些组分相对于彼此定位至 允许标记蛋白或治疗性蛋白质的表达。 本发明的增强剂可用于从人脑和/或脊髓细胞的混合群体中分离富集或纯化的运动神经元群体的方法。 此外，本发明的增强剂可以用于治疗靶向运动神经元的方法。

公开(公告)号：US06385502B1

公开(公告)日：2002-05-07

申请号：US09280003

申请日：1999-03-29

申请人： Shigeyoshi Takagi ,  Takahiro Nakano

发明人： Shigeyoshi Takagi ,  Takahiro Nakano

IPC分类号： G06F1900

CPC分类号： G05B19/4185 ,  G05B2219/31104 ,  G05B2219/31205 ,  G05B2219/31455 ,  G05B2219/33182 ,  G05B2219/34038 ,  G05B2219/42247 ,  Y02P90/18

摘要： A system for machining a component part having a race groove a along which ball elements run include a machine tool 3 for performing a machining operation on the component part, an acquisition unit 8 for acquiring information related to the machining operation, a control unit 4 for controlling the machine tool 3 based on the information acquired by the acquisition unit 8, a remote information processor 10 installed at a site remote from the control unit 4, and a communication system 9 for connecting the control unit 4 and the remote information processor 10 through a communication line 12. The remote information processor 10 has a capability of acquiring the information, acquired by the acquisition unit 8, through the control unit 4 and the communication line 12 and transmitting such information to the control unit 4 so that the component part can be machined to suit to a particular machining condition while satisfying a stabilized dimension.

摘要翻译： 用于加工具有滚珠元件运行的滚道槽a的部件的系统包括用于对部件进行加工操作的机床3，用于获取与加工操作有关的信息的获取单元8，用于 基于由获取单元8获取的信息，安装在远离控制单元4的位置的远程信息处理器10以及用于通过控制单元4和远程信息处理器10连接的通信系统9来控制机床3 远程信息处理器10具有通过控制单元4和通信线路12获取由获取单元8获取的信息的能力，并将这些信息发送到控制单元4，使得组件可以 被加工以适应特定的加工条件，同时满足稳定的尺寸。

公开(公告)号：US4884129A

公开(公告)日：1989-11-28

申请号：US171714

申请日：1988-03-22

申请人： Naoki Ozawa ,  Toshiyuki Akiyama ,  Kenji Takahashi ,  Itaru Mimura ,  Takahiro Nakano

发明人： Naoki Ozawa ,  Toshiyuki Akiyama ,  Kenji Takahashi ,  Itaru Mimura ,  Takahiro Nakano

IPC分类号： H04N9/07 ,  H04N9/04 ,  H04N9/64

CPC分类号： H04N9/045 ,  H04N9/646

摘要： A signal processing apparatus for use with an imaging device having an image signal output circuit inherently generating noise in operation so that noise may be superposed on the image signal. The apparatus comprises a noise suppressor having a sampling and holding circuit for producing noise-suppressed pixel signals carrying different color information to contribute to suppression of noise superposed on the image signal and at the same time to demodulation of chroma signals representative of color components of an image and adders for producing a sum of and a difference between the noise-suppressed pixel signals to thereby produce a luminance signal and chroma signals for an image. The apparatus may further comprise a gain control circuits interposed between the sampling and holding circuit and the difference producing adder so that the amplitudes of the noise-suppressed pixel signals are leveled to improve the color purity of an image reproduced from the image signal.

摘要翻译： 一种用于具有图像信号输出电路的成像装置的信号处理装置，所述图像信号输出电路在操作中固有地产生噪声，使得噪声可以叠加在图像信号上。 该装置包括具有采样和保持电路的噪声抑制器，用于产生携带不同颜色信息的噪声抑制像素信号，以有助于抑制叠加在图像信号上的噪声，并且同时解调代表色差信号的色度信号 图像和加法器，用于产生噪声抑制像素信号之和的差和差，从而产生用于图像的亮度信号和色度信号。 该装置还可以包括插入在采样和保持电路和差产生加法器之间的增益控制电路，使得抑制噪声的像素信号的幅度被调平以提高从图像信号再现的图像的色纯度。

公开(公告)号：US10322902B2

公开(公告)日：2019-06-18

申请号：US15783550

申请日：2017-10-13

申请人： Takahiro Nakano

发明人： Takahiro Nakano

IPC分类号： B65H31/30 ,  B42C1/12 ,  G03G15/00 ,  B65H29/14 ,  B65H31/02 ,  B65H31/36 ,  B65H43/00 ,  B65H45/18 ,  B42B4/00

摘要： Disclosed herein is a sheet processing apparatus comprising a sheet tray configured to hold a bundle composed of the sheets fed from conveyance rollers, a wait path configured to keep waiting following sheets upstream the conveyance rollers, an accumulating tray configured to hold a sheet bundle, delivery rollers configured to nip the sheet bundle mounted on the sheet tray and the following sheets, to set off from one another, and to deliver them to the accumulating tray, and to switch back the following sheets to the sheet tray, and a conveyance member configured to convey the following sheets from the sheet tray.

公开(公告)号：US09069471B2

公开(公告)日：2015-06-30

申请号：US13249310

申请日：2011-09-30

申请人： Takahiro Nakano

发明人： Takahiro Nakano

IPC分类号： G06F12/08 ,  G06F12/06 ,  G06F3/06

CPC分类号： G06F3/0613 ,  G06F3/0631 ,  G06F3/0643 ,  G06F3/0685

摘要： An information system comprises: a storage system including a processor, a memory, and a plurality of virtual volumes to be allocated pages from a storage pool of volumes; and a metadata server which, upon receiving from a client a write request containing file data to be written to a virtual volume in the storage system, returns the write request to the client with parallel information which is added to a data layout of the file data to be written in the virtual volume. The storage system, upon receiving the write request with the parallel information, allocates, based on the parallel information, pages from the storage pool to the virtual volume for writing the file data, so that the data layout is striped and the allocated pages fit striped data access according to the striped data layout.

摘要翻译： 信息系统包括：存储系统，包括处理器，存储器和要从卷的存储池分配的页面的多个虚拟卷; 以及元数据服务器，其在从客户端接收到包含要写入存储系统中的虚拟卷的文件数据的写入请求时，将写入请求返回给客户机，该并行信息被添加到文件数据的数据布局 写入虚拟卷。 存储系统在接收到具有并行信息的写请求时，基于并行信息将从存储池的页面分配给用于写入文件数据的虚拟卷，使得数据布局被条带化并且分配的页面适合条带 根据条带数据布局进行数据访问。

公开(公告)号：US08756199B2

公开(公告)日：2014-06-17

申请号：US12678235

申请日：2010-03-01

申请人： Atsushi Sutoh ,  Masanori Takata ,  Hitoshi Kamei ,  Nobumitsu Takaoka ,  Takahiro Nakano ,  Akio Shimada

发明人： Atsushi Sutoh ,  Masanori Takata ,  Hitoshi Kamei ,  Nobumitsu Takaoka ,  Takahiro Nakano ,  Akio Shimada

IPC分类号： G06F7/02 ,  G06F17/30

CPC分类号： G06F17/3012 ,  G06F17/30079 ,  G06F17/30082 ,  G06F17/30221

摘要： Time required for a file server to determine files to be migrated from a first storage region to a second storage region is reduced. A file service system coupled to the storage system for providing a first storage region and a second storage region stores identifiers of files that have been accessed by a client, in accessed file identifier information and determines the files to be migrated from the first storage region to the second storage region based on metadata of the files stored in the first storage region and the accessed file identifier information.

摘要翻译： 减少文件服务器确定要从第一存储区域迁移到第二存储区域的文件所需的时间。 耦合到存储系统的用于提供第一存储区域和第二存储区域的文件服务系统存储由客户端访问的文件的标识符，并将其从第一存储区域迁移到 基于存储在第一存储区域中的文件的元数据和所访问的文件标识符信息的第二存储区域。

公开(公告)号：US20140163933A1

公开(公告)日：2014-06-12

申请号：US14236986

申请日：2012-05-24

申请人： Hisaya Ishibashi ,  Takahiro Nakano ,  Satoshi Nagahara

发明人： Hisaya Ishibashi ,  Takahiro Nakano ,  Satoshi Nagahara

IPC分类号： G06F17/50

CPC分类号： G06F17/50 ,  G05B19/41885 ,  G05B2219/32265 ,  G05B2219/32357 ,  G05B2219/32366 ,  G06F17/5009 ,  G06Q10/04 ,  G06Q10/06 ,  G06Q50/04 ,  Y02P90/14 ,  Y02P90/20 ,  Y02P90/26 ,  Y02P90/265 ,  Y02P90/30

摘要： Conventional manufacturing line designing had a problem in that, when making the number of places for keeping partly-finished products (number of buffers) more appropriate in a factory layout, calculation took considerable time because a design proposal was selected through trial and error and a manufacturing line simulation was executed each time a design proposal was selected. A manufacturing line designing apparatus according to the present invention is characterized in being provided with: a production simulation execution unit that predicts future production capacity and the number of partly-finished products by simulating a manufacturing line; a buffer utilization rate calculation unit that calculates a buffer utilization rate that is the ratio of the number of buffers for each of the processes with respect to the maximum number of buffers and the average number of buffers during the simulation period; and a number-of-buffers reducing unit that reduces the number of buffers successively, starting from a process having a low buffer utilization rate, and repeats the calculation until the total number of buffers is minimized, to determine the number of buffers to be placed between the processes.

摘要翻译： 传统的生产线设计存在的问题在于，当在工厂布局中使保持部分成品（缓冲区数）更适合的位置数量时，计算需要相当长的时间，因为设计方案是通过试错选择的 每次选择设计方案时都会执行生产线模拟。 根据本发明的生产线设计装置的特征在于具有：生产模拟执行单元，其通过模拟生产线来预测未来的生产能力和部分成品的数量; 缓冲器利用率计算单元，其计算缓冲器利用率，所述缓冲器利用率是所述处理中的每个缓冲器的数量相对于所述最大缓冲器数量和所述模拟期间中的平均缓冲器数量的比率; 以及从具有低缓冲器利用率的处理开始，连续减少缓冲器数量的缓冲器数量减少单元，并重复计算，直到缓冲器总数最小化，以确定要放置的缓冲器的数量 之间的过程。

公开(公告)号：US08678631B2

公开(公告)日：2014-03-25

申请号：US13065757

申请日：2011-03-29

申请人： Motonori Tominaga ,  Daisuke Nishitani ,  Takahiro Nakano

发明人： Motonori Tominaga ,  Daisuke Nishitani ,  Takahiro Nakano

IPC分类号： B60Q1/04

CPC分类号： F21S45/60 ,  F21S41/147 ,  F21S45/43 ,  F21S45/47 ,  F21S45/48 ,  F21S45/49

摘要： A vehicle headlamp assembly including a housing case and a lens cover forming a light chamber, a projection lens, a shade and a light source are arranged within the light chamber in that order along an optical axis of the headlamp assembly. A radiating member includes plate-shaped radiating fins vertically placed in the light chamber, for radiating heat energy generated by the light source to surrounding air. A plate is arranged at a right angle to the radiating fins in the light chamber, for controlling air-convection flow around the radiating fins.

摘要翻译： 包括壳体和形成光腔的透镜盖，投影透镜，阴影和光源的车辆前照灯组件沿着前照灯组件的光轴依次布置在灯室内。 辐射构件包括垂直放置在光室中的板状散热片，用于将由光源产生的热能辐射到周围空气。 板与光室中的散热片成直角布置，用于控制散热片周围的空气对流。

公开(公告)号：US08645645B2

公开(公告)日：2014-02-04

申请号：US12348339

申请日：2009-01-05

申请人： Hitoshi Kamei ,  Takahiro Nakano

发明人： Hitoshi Kamei ,  Takahiro Nakano

IPC分类号： G06F12/16

CPC分类号： G06F3/0619 ,  G06F3/0647 ,  G06F3/065 ,  G06F3/0665 ,  G06F3/0683 ,  G06F3/0689 ,  G06F17/30221 ,  G06F17/30233

摘要： There is provided a file management method of a hierarchy management file system capable of preventing an access performance from dropping when a user accesses to a file. According to the method, a server creates file systems in high-speed and low-speed volumes and a file-sharing server virtually integrates those file systems into one system as a pseudo file system. Then, the server moves a file to be moved to the file system created in the low-speed volume in advance, not when an access is made to the file. When a user accesses to the file after that, the user directly accesses to destination without requiring to copy the file, so that the accessing performance may be prevented from dropping.

摘要翻译： 提供了一种层次管理文件系统的文件管理方法，其能够防止访问性能在用户访问文件时丢弃。 根据该方法，服务器以高速和低速卷创建文件系统，并且文件共享服务器将这些文件系统虚拟地整合为一个系统作为伪文件系统。 然后，服务器将要移动的文件移动到提前在低速卷中创建的文件系统，而不是对文件进行访问。 当用户在此之后访问该文件时，用户直接访问目的地而不需要复制文件，从而可以防止访问性能下降。

公开(公告)号：US08612715B2

公开(公告)日：2013-12-17

申请号：US13529626

申请日：2012-06-21

申请人： Hiroshi Mine ,  Hitoshi Kamei ,  Takahiro Nakano

发明人： Hiroshi Mine ,  Hitoshi Kamei ,  Takahiro Nakano

IPC分类号： G06F12/02

CPC分类号： G06F3/0631 ,  G06F3/0605 ,  G06F3/0649 ,  G06F3/0665 ,  G06F3/0685 ,  G06F17/30221

摘要： A storage system 1000 providing a storage area to an external device 1500 comprises a plurality of storage apparatuses 1100, 1200 and 1300 of different performance capabilities, and a storage controller 2600. The storage controller 2600 holds storage cost coefficients 3202 of the respective storage apparatuses 1100, 1200 and 1300, user cost allocation information 3302 for each user using the storage system 1000 from the external device 1500, and user cost distribution information 3402 that defines, for each user, proportions of an available space amount distributed to the storage apparatuses 1100, 1200 and 1300. The storage controller 2600 calculates an ideal utilization 3502 for each user, from the storage cost coefficients 3202 and the user cost distribution information 3402, and allocates, for each user, the ideal utilization 3502 to each of the storage apparatuses 1100, 1200 and 1300, in the order of the performance capabilities from highest to lowest.

摘要翻译： 向外部设备1500提供存储区域的存储系统1000包括具有不同性能的多个存储设备1100,1200和1300以及存储控制器2600.存储控制器2600保存各个存储设备1100的存储成本系数3202 ，1200和1300，用于使用来自外部设备1500的存储系统1000的每个用户的用户成本分配信息3302以及为每个用户定义分配给存储设备1100的可用空间量的比例的用户成本分配信息3402， 存储控制器2600根据存储成本系数3202和用户成本分配信息3402计算每个用户的理想利用率3502，并且为每个用户分配理想利用3502到每个存储设备1100， 1200和1300，按性能能力的顺序从最高到最低。