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61.发明授权Tetra- and penta-o-benzyl-protected, C-4 activated-epicatechin and -catechin monomers and processes for their preparation and use 失效四 - 和五 - 邻 - 苄基保护的C-4活化表儿茶素和儿茶素单体及其制备和使用方法公开(公告)号：US07507831B2
公开(公告)日：2009-03-24
申请号：US11329467
申请日：2006-01-11
IPC分类号： C07D417/12 , C07D311/30
CPC分类号： C07D311/62 , C07D417/12 , C07D417/14
摘要： Various processes are disclosed for preparing protected epicatechin oligomers having (4β,8)-interflavan linkages. In one process, a tetra-O-protected epicatechin monomer or oligomer is coupled with a protected, C-4 activated epicatechin monomer in the presence of an acidic clay such as a mortmorillonite clay. In another process, a 5,7,3′,4′-benzyl protected or a 3 -acetyl-, 5,7,3′,4′-benzyl protected epicatechin or catechin monomer or oligomer is reacted with 3 -O-acetyl-4-[(2-benzothiazolyl)thio]-5,7,3′,4′-tetra-O-benzylepicatechin in the presence of silver tetrafluoroborate. In another process, two 5,7,3′,4′-benzyl protected epicatechin monomers activated with 2-(benzothiazolyl)thio groups at the C-4 positions are cross-coupled in the presence of silver tetrofluoroborate. A process is also disclosed for reacting an unprotected epicatechin or catechin monomer with 4-(benzylthio) epicatechin or catechin. The use of naturally-derived and synthetically-prepared procyanidin (4β,8)4-pentamers to treat cancer is also disclosed.
摘要翻译： 公开了用于制备具有（4beta，8） - 间连环的保护的表儿茶素低聚物的各种方法。 在一个方法中，四氧化物保护的表儿茶素单体或低聚物在保护的C-4活化的表儿茶素单体的存在下，在酸性粘土如失
桑土粘土的存在下偶合。 在另一种方法中，将5,7,3'，4'-苄基保护或3-乙酰基，5,7,3'，4'-苄基保护的表儿茶素或儿茶素单体或低聚物与3-O-乙酰基 -4 - [（2-苯并噻唑基）硫基] -5,7,3'，4'-四-O-苯甲酸酯在四氟硼酸银的存在下反应。 在另一种方法中，在C-4位上用2-（苯并噻唑基）硫基活化的两个5,7,3'，4'-苄基保护的表儿茶素单体在四氟硼酸银的存在下交联。 还公开了使未保护的表儿茶素或儿茶素单体与4-（苄硫基）表儿茶素或儿茶素反应的方法。 还公开了使用天然衍生的和合成制备的原花青素（4beta，8）4-五聚体来治疗癌症。-
62.发明授权公开(公告)号：US07318372B2
公开(公告)日：2008-01-15
申请号：US10953633
申请日：2004-09-29
申请人： John Charles Cooke
发明人： John Charles Cooke
IPC分类号： A47J31/00
CPC分类号： A47J31/46 , A47J31/3628
摘要： A beverage making apparatus for preparing a plurality of different beverages, the apparatus comprising: a receptacle station for receiving a receptacle for the beverage; a capsule receiving station having walls defining a cavity for receiving a capsule containing a beverage making ingredient; an inlet for introducing water into a capsule in the station to produce a beverage; and a beverage outlet for directing an outflow of beverage from the cavity to the receptacle station; wherein the apparatus comprises a plurality of different beverage outlets that are interchangeable for making different beverages.
摘要翻译： 一种用于制备多种不同饮料的饮料制备装置，所述装置包括：容纳台，用于容纳饮料的容器; 胶囊接收站具有限定用于容纳含有饮料制造成分的胶囊的空腔的壁; 用于将水引入站内的胶囊以产生饮料的入口; 以及饮料出口，用于将饮料从所述空腔流出到所述容器台; 其中所述装置包括可互换用于制造不同饮料的多个不同饮料出口。
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公开(公告)号：US06991819B2
公开(公告)日：2006-01-31
申请号：US10297828
申请日：2001-06-13
CPC分类号： A23L33/175 , A23L27/70 , A23L29/06 , A23L29/065 , A23L33/105 , A23L33/15 , A23P10/30 , A23V2002/00 , A23V2250/21 , A23V2250/70 , A23V2250/062 , A23V2250/206
摘要： A food product containing instable additives, having a food compound consisting of a porous matrix which is provided with a substrate containing instable additives, obtainable by a process in which, in a first step, the matrix is exposed to a partial vacuum; in a second step, the substrate containing instable additives is applied, in a flowable form, to the matrix under the partial vacuum; and in a third step, the pressure is increased, so that the substrate is forced into the pores of the porous matrix and substantially fills them out.
摘要翻译： 一种含有不稳定添加剂的食品，其具有由多孔基质组成的食品化合物，所述多孔基质具有含有不稳定添加剂的基质，可通过第一步骤将基质暴露于部分真空中的方法获得; 在第二步骤中，将含有不稳定添加剂的基材以可流动的形式在部分真空下施加到基质上; 并且在第三步骤中，压力增加，使得衬底被迫进入多孔基质的孔中并基本上将其填充出来。
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公开(公告)号：US06932993B2
公开(公告)日：2005-08-23
申请号：US10168734
申请日：2000-12-15
摘要： Process for the production of filled food hollow mouldings, in which each hollow moulding has at least one cavity, which is open to the environment and filled with a filling material solid at ambient temperature and having a cross-sectional dimension between approximately 0.25 mm2 and approximately 1 cm2, characterized in that in a first stage the hollow mouldings are coated at reduced pressure with the filling material, a filing material coating temperature being set in such a way that the filling material is flowable and in which in a second step the pressure is raised, so that the flowable coating material enters the cavities.
摘要翻译： 用于生产填充食品中空成型品的方法，其中每个中空成型体具有至少一个空腔，该空腔对环境是开放的，并且在环境温度下填充有固体的填充材料，并且其横截面尺寸在大约0.25mm 2和约1cm 2，其特征在于，在第一阶段中，中空模制品在减压下用填充材料涂覆，填充材料涂覆温度以这种方式设置 填充材料是可流动的，并且其中在第二步骤中压力升高，使得可流动的涂料进入空腔。
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65.发明申请公开(公告)号：US20050181097A1
公开(公告)日：2005-08-18
申请号：US11051743
申请日：2005-02-04
申请人： Stewart Townsend , Kristin Boyle , Dan Beyer , Oscar Ortiz , Allan Torney , Frank Shields , Helen Munday , Alexandre Mendes , Angel Hernandez , Emine Unlu , Saeed Ahmed , Peter Slusarczyk , Christopher Frank , Liisa Mooney , Kasim Zubair , Tiffany Bierer
发明人： Stewart Townsend , Kristin Boyle , Dan Beyer , Oscar Ortiz , Allan Torney , Frank Shields , Helen Munday , Alexandre Mendes , Angel Hernandez , Emine Unlu , Saeed Ahmed , Peter Slusarczyk , Christopher Frank , Liisa Mooney , Kasim Zubair , Tiffany Bierer
摘要： The present invention is directed to a nutritionally complete and preferably balanced, shelf stable pet food product, a method of feeding the pet food product to an animal and a process of manufacturing that pet food product. The method of feeding an animal includes the step of feeding a preferred pet food product to the animal, wherein the pet food product is a nutritionally complete meal and is configured such that the animal can hold the product with its appendages while eating the product.
摘要翻译： 本发明涉及营养完全且优选平衡的保存稳定的宠物食品，将宠物食品喂给动物的方法和制造该宠物食品的方法。 饲养动物的方法包括将优选的宠物食品喂给动物的步骤，其中宠物食品是营养完全的膳食，并且被配置成使得动物在食用食物时能够以其附属物容纳产品。
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公开(公告)号：US6156791A
公开(公告)日：2000-12-05
申请号：US198551
申请日：1998-11-23
IPC分类号： A23L1/30 , A23G1/02 , A23G1/30 , A61K31/35 , A61K31/352 , A61K31/353 , A61K31/7048 , A61K31/78 , A61K36/00 , A61K36/18 , A61K36/185 , A61P35/00 , C07D311/62 , C07D311/78 , A01N43/16
CPC分类号： A61K31/78 , A23L33/105 , A61K31/353 , A61K36/185 , C07D311/62
摘要： Disclosed and claimed are cocoa extracts such as polyphenols or procyanidins, methods for preparing such extracts, as well as uses for them, especially as antineoplastic agents and antioxidants. Disclosed and claimed are antineoplastic compositions containing cocoa polyphenols or procyanidins-and methods for treating patients employing the compositions. Additionally disclosed and claimed is a kit for treating a patient in need of treatment with an antineoplastic agent containing cocoa polyphenols or procyanidins as well as a lyophilized antineoplastic composition containing cocoa polyphenols or procyanidins. Further, disclosed and claimed is the use of the invention in antioxidant, preservative and topiosomerase-inhibiting compositions and methods.
摘要翻译： 披露和要求的是可可提取物如多酚或原花青素，制备这些提取物的方法，以及它们的用途，特别是抗肿瘤剂和抗氧化剂。 披露和要求的是含有可可多元酚或原花青素的抗肿瘤组合物以及用于治疗使用该组合物的患者的方法。 另外公开并要求保护的是用于治疗需要用含有可可多元酚或原花青素的抗肿瘤剂治疗的患者以及含有可可多元酚或原花青素的冻干抗肿瘤组合物的试剂盒。 此外，公开并要求保护的是本发明在抗氧化剂，防腐剂和拓扑异构酶抑制组合物和方法中的用途。
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公开(公告)号：US5356333A
公开(公告)日：1994-10-18
申请号：US847015
申请日：1992-07-15
摘要： A coin handling system includes two coin escrows which receive respectively high and low denomination coins. Each escrow comprises a helical structure with coins individually supported between successive turns of the helix. Each helical structure can store coins of any denomination in any location, and has exits at both ends to allow control over the sequence in which the coins are sent to a cash box.
摘要翻译： PCT No.PCT / GB90 / 01526 Sec。 371日期：1992年7月15日 102（e）日期1992年7月15日PCT 1990年10月4日PCT PCT。 出版物WO91 / 06073 日期1991年5月2日。硬币处理系统包括两个硬币托管，分别接收高和低面额硬币。 每个暂时保留包括螺旋结构，其硬币分别支撑在螺旋的连续匝之间。 每个螺旋结构可以在任何位置存储任何面额的硬币，并且在两端都有出口，以便控制硬币被送到现金箱的顺序。
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公开(公告)号：US5130153A
公开(公告)日：1992-07-14
申请号：US469525
申请日：1990-05-07
申请人： David McIlroy , Luc Jacops , Jef Kempen , Adrian Trim
发明人： David McIlroy , Luc Jacops , Jef Kempen , Adrian Trim
CPC分类号： A23L7/196 , A23L7/1975
摘要： According to the present invention, there is provided a process for par-boiling rice, comprising the steps of: (a) treating the rice with water at a temperature up to its boiling point to increase its water content to 17 to 28%; (b) steaming the soaked rice at a temperature from 100.degree. to 125.degree. C. to increase its water content to 19 to 30%; (c) heating the steamed rice, in a sealed vessel, under pressure and using dry heat, to a minimum temperature of approximately t.degree. C., wherein t=195-2.5 M and M is the moisture content of the steamed rice in %, for from 1 to 5 minutes; (d) reducing the pressure on the rice over a period of 1 to 10 minutes to atmospheric pressure, thereby allowing water to evaporate from the heated rice to reduce its temperature to approximately 100.degree. C. and its water content to 17 to 24%; and (e) drying the partially dried rice to microbiological stability. The product of the present invention has better consumer appeal than conventional par-boiled rice.
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公开(公告)号：US4733766A
公开(公告)日：1988-03-29
申请号：US805114
申请日：1985-12-04
申请人： Mark Roberts , Adrian Lewis
发明人： Mark Roberts , Adrian Lewis
摘要： The arrival of a coin in a coin checking apparatus is detected by arranging for the coin to hit a member (16). The vibration caused by the impact causes a piezoelectric element (36,36a) to give a transient output signal which is used to switch on electronic circuitry of the coin checking apparatus. The circuitry is normally switched off and thus over a period of time the average power consumption of the coin checking apparatus is low so that it can be satisfactorily run from a battery.
摘要翻译： 通过布置硬币来撞击构件（16）来检测硬币到达硬币检查装置。 由冲击引起的振动使得压电元件（36,36a）产生用于打开硬币检查装置的电子电路的瞬态输出信号。 电路通常被关闭，因此在一段时间内硬币检查装置的平均功耗很低，从而可以令人满意地从电池运行。
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公开(公告)号：US4611205A
公开(公告)日：1986-09-09
申请号：US542144
申请日：1983-10-14
申请人： David Eglise
发明人： David Eglise
IPC分类号： G07F5/22 , G06F17/40 , G06Q50/00 , G07F5/18 , G07F9/00 , G07F9/08 , H04Q9/00 , G06F7/00 , G06K5/02
CPC分类号： G07F11/002 , G07F5/18 , G07F9/026 , G07F9/08
摘要： A system for collecting data from machines is particularly but not exclusively, suited for use as a vending machine audit system, and, in the preferred embodiment, comprises an audit controller which records transaction data relating to the operation of the machine and periodically is caused to transfer the data into a data storage module in the form of a non-volatile memory. The module can be removed and inserted into a down-loading machine at a central location which extracts the data and uses it to provide a transaction record.The audit controller stores in the module a predetermined indication code only after first checking that the transaction data has been correctly stored in the module. The indication code signifies to the down-loading machine that the data was correctly transferred to the module. There is thus no need to lock the module into the controller during data transfer, because removal of the module during data transfer will not result in the production of an incorrect transaction record.Transfer of data to the module takes place only if the module stores an appropriate security code. If the customer forgets his own security code, access to the data is permitted by storing in the module a "skeleton" code known to the manufacturer.
摘要翻译： 用于从机器收集数据的系统特别但不排他地适用于自动售货机审计系统，并且在优选实施例中，包括审核控制器，其记录与机器的操作有关的交易数据， 以非易失性存储器的形式将数据传输到数据存储模块中。 该模块可以被移除并插入到提取数据并用它来提供交易记录的中央位置的下载机器中。 在第一次检查事务数据已被正确地存储在模块中之后，审计控制器在模块中存储预定的指示代码。 指示代码表示下载机器将数据正确传输到模块。 因此，在数据传输期间无需将模块锁定到控制器中，因为在数据传输期间移除模块不会导致生成不正确的事务记录。 仅当模块存储适当的安全代码时，才会将数据传输到模块。 如果客户忘记自己的安全代码，则可以通过在模块中存储制造商已知的“骨架”代码来访问数据。
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