Method and compositions for analysis of pentraxin receptors as indicators of disease
    61.
    发明授权
    Method and compositions for analysis of pentraxin receptors as indicators of disease 失效
    用于分析五倍体受体作为疾病指标的方法和组合物

    公开(公告)号:US06872541B2

    公开(公告)日:2005-03-29

    申请号:US09915892

    申请日:2001-07-25

    Inventor: Rhonda Ann Mills

    CPC classification number: G01N33/564 G01N33/54313

    Abstract: A kit for assessing the level of pentraxin-binding moieties on particles in a biological sample containing a ligand comprising a pentraxin is useful in a method of assessing pentraxin-binding of particles for use in diagnosis of disease or abnormality. The method includes the steps of (a) exposing a biological test sample containing particles that comprise a pentraxin-binding receptor from a test subject to a ligand comprising a pentraxin in the presence of calcium; (b) determining quantitatively the level of binding between particles and ligand in said test sample; and (c) comparing the level of binding in said test sample to the level of binding in a control biological sample containing said particles from a healthy subject of the same species as the subject supplying the test sample. A change in the level of binding in said test sample from that of the control sample is indicative of disease or abnormality.

    Abstract translation: 用于评估含有包含pentraxin的配体的生物样品中颗粒上五倍体结合部分水平的试剂盒可用于评估用于诊断疾病或异常的颗粒的五倍体结合的方法。 该方法包括以下步骤:(a)在钙的存在下将含有来自测试对象的包含五倍体结合受体的颗粒的生物测试样品暴露于包含五倍体的配体; (b)定量测定所述测试样品中颗粒和配体之间的结合水平; 和(c)将所述测试样品中的结合水平与含有与供应测试样品的受试者相同物种的健康受试者含有所述颗粒的对照生物样品中的结合水平进行比较。 所述测试样品与对照样品的结合水平的变化指示疾病或异常。

    Pressurized chamber doctor blade
    62.
    发明授权
    Pressurized chamber doctor blade 有权
    加压室刮刀

    公开(公告)号:US06872257B2

    公开(公告)日:2005-03-29

    申请号:US10233162

    申请日:2002-08-30

    CPC classification number: B05C1/0813

    Abstract: The invention pertains to a pressure chamber scraper for application of a liquid medium onto a rotating drum, said pressure chamber scraper having an axially extending scraper head, that together with an axially extending dosing scraper touching the mantle surface of the drum and with a sealing scraper forms a chamber in the circumferential direction, in said chamber there is an axially extending displacement element to form a pressure compartment and an outlet compartment and leaving an application gap to the mantle surface of the drum, and the liquid medium for wetting of the mantle surface flows through said gap, wherein the medium is supplied through an inlet opening into the pressure compartment. According to the invention, it is proposed that the displacement element and scraper head have mutually facing contact surfaces which bound at least one gap between them which opens into the pressure compartment and connects it to the inlet opening, so that the medium can move into the pressure compartment. With this kind of design it is possible to configure the gap as narrow as desired.

    Abstract translation: 本发明涉及一种用于将液体介质施加到旋转滚筒上的压力室刮刀,所述压力室刮刀具有轴向延伸的刮刀头,其与轴向延伸的剂量刮刀接触滚筒的外壳表面和密封刮刀 在圆周方向上形成一个腔室,在所述腔室中有一个轴向延伸的位移元件,以形成一个压力隔室和一个出口隔室,并留下与滚筒的外套表面的应用间隙,以及用于润湿地幔表面的液体介质 流过所述间隙,其中介质通过入口进入压力室。 根据本发明,提出了位移元件和刮刀头具有相互面对的接触表面,该接触表面将它们之间的至少一个间隙结合到开口的压力室中,并将其连接到入口开口,使得介质可以移动到 压力室。 通过这种设计,可以根据需要将间隙配置成窄。

    Tarnish-resistant handbell and its method of manufacture
    63.
    发明授权
    Tarnish-resistant handbell and its method of manufacture 失效
    防腐手环及其制造方法

    公开(公告)号:US06871613B2

    公开(公告)日:2005-03-29

    申请号:US10456719

    申请日:2003-06-06

    CPC classification number: G10K1/08 G10K1/071

    Abstract: A handbell has a bell body with an inner surface engageable by a clapper to produce a sound corresponding to a note of the musical scale and an outer surface with a vapor deposited nitride layer that resists tarnish. Preferably, the vapor deposited nitrate layer has a thickness of less than about 5 microns and does not adversely affect the sound produced when the handbell is rung. In addition, preferably the vapor deposited nitrate layer is zirconium nitride or titanium nitride and has a Vickers hardness (HV) of at least 2300. A method of making and/or refurbishing a handbell is also disclosed.

    Abstract translation: 手铃具有钟形体,其具有可由拍子接合的内表面,以产生对应于音阶的音符的声音和具有抵抗晦暗的气相沉积氮化物层的外表面。 优选地,蒸汽沉积的硝酸盐层具有小于约5微米的厚度,并且不会不利地影响当手把响起时产生的声音。 此外,优选地,蒸镀的硝酸盐层是氮化锆或氮化钛,并且维氏硬度(HV)至少为2300.还公开了制造和/或翻新手把的方法。

    Sliding contact guide for transmission device
    64.
    发明授权
    Sliding contact guide for transmission device 有权
    传动装置滑动接触导轨

    公开(公告)号:US06849014B2

    公开(公告)日:2005-02-01

    申请号:US10347655

    申请日:2003-01-21

    CPC classification number: F16H7/18 F16H2007/0872

    Abstract: In a sliding contact guide for a chain, a guide body is composed of a shoe having a front surface on which the chain slides, and a plate-receiving portion provided on the back of the shoe. The shoe and plate-receiving portion are integrally molded from a synthetic resin. A reinforcing plate is inserted and fitted into a longitudinal slot in the plate-receiving and the sliding contact guide is attached to a frame by a pivot pin which extends through aligned mounting holes in the guide body and the reinforcing plate. Locking pieces formed in the plate-receiving portion, have tapered surfaces on their tips that engage locking holes in the plate and exert a biasing force on edges of the locking holes which urges the plate against the back of the shoe. The reinforcing plate and the guide body are reliably secured together and, even when the guide is vibrated, movement of the reinforcing plate in the slot of the guide body is prevented, so that low noise and long life are attained.

    Abstract translation: 在链条的滑动接触引导件中,引导体由具有链条滑动的前表面的鞋和设置在鞋背上的板接收部构成。 鞋和板接收部分由合成树脂一体模制。 加强板插入并装配在板接收件的纵向槽中,并且滑动接触引导件通过枢轴销附接到框架,枢轴销延伸穿过引导体和加强板中的对准的安装孔。 形成在板接收部分中的锁定件在其尖端上具有接合板中的锁定孔的锥形表面,并且在锁定孔的边缘上施加偏压力,其将板抵靠在鞋的后部。 加强板和引导体被可靠地固定在一起,并且即使当引导件振动时,也可以防止加强板在引导体的槽中的移动,从而达到低噪声和长寿命。

    Quartz crystal microbalance with feedback loop for automatic gain control
    65.
    发明授权
    Quartz crystal microbalance with feedback loop for automatic gain control 有权
    具有反馈回路的石英晶体微量天平,用于自动增益控制

    公开(公告)号:US06848299B2

    公开(公告)日:2005-02-01

    申请号:US10630072

    申请日:2003-07-30

    CPC classification number: G01N29/036 G01G3/13 G01N2291/0256

    Abstract: An analytical apparatus, such as a quartz crystal microbalance, comprises a piezoelectric sensor and an oscillator circuit, coupled to the sensor, to oscillate at a frequency substantially determined by a resonant frequency of the sensor, and to provide an output signal at the oscillator frequency at an output. The oscillator circuit maintains a substantially constant drive signal to the piezoelectric sensor by an AGC (33) within a feedback loop of the oscillator. The gain control signal is used as an indication of the Q of the piezoelectric sensor. The drive signal to the sensor is made substantially sinusoidal by ensuring that all the elements in the feedback loop providing signal gain and attenuation are configured to operate in a substantially linear mode.

    Abstract translation: 诸如石英晶体微量天平的分析装置包括耦合到传感器的压电传感器和振荡器电路,以基本上由传感器的谐振频率确定的频率振荡,并且以振荡器频率提供输出信号 在输出。 振荡器电路通过振荡器的反馈环路内的AGC(33)向压电传感器维持基本恒定的驱动信号。 增益控制信号用作压电传感器的Q的指示。 通过确保提供信号增益和衰减的反馈回路中的所有元件被配置为以基本上线性的方式工作,使传感器的驱动信号基本上是正弦的。

    Method of producing bushing
    66.
    发明授权
    Method of producing bushing 有权
    生产套管的方法

    公开(公告)号:US06842982B2

    公开(公告)日:2005-01-18

    申请号:US10612160

    申请日:2003-07-02

    Abstract: By press-fitting a cylindrical blank into a die with one of a pair of punches, and at the same time press-fitting small diameter end portions and tapered portions of the pair of punches into both ends of the cylindrical blank while restraining both end surfaces of the blank with cylindrical members movable on the outsides of the punches, the external circumferential surface of the blank is finish molded to the required diameter by the internal circumferential surface of the die and, at the same time, tapered surfaces are formed on the inner circumferential surface in both ends of the blank. The process produces a bushing with its internal surfaces accurately coaxial, and with the external surface accurately formed to the required diameter.

    Abstract translation: 通过用一对冲头中的一个将圆柱形坯料压入模具,同时将一对冲头的小直径端部和锥形部分压入圆柱形坯料的两端,同时限制两个端面 在可以在冲头外侧移动的圆筒形构件的坯料上,坯料的外周面通过模具的内周面被精加工成所需的直径,同时在内部形成锥面 空白两端的圆周表面。 该过程产生一个衬套,其内表面精确地同轴,外表面精确地形成所需的直径。

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