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134 条记录 (耗时 0.025 秒)

    High Refractive-Index, Hydrophilic Monomers and Polymers, and Ophthalmic Devices Comprising Such Polymers
    63.
    发明申请
    High Refractive-Index, Hydrophilic Monomers and Polymers, and Ophthalmic Devices Comprising Such Polymers 审中-公开
    高折射率，亲水单体和聚合物以及包含这种聚合物的眼科装置

    公开(公告)号：US20080183006A1

    公开(公告)日：2008-07-31

    申请号：US12060322

    申请日：2008-04-01

    申请人： Joseph C. Salamone ,  Jay F. Kunzler ,  Richard M. Ozark

    发明人： Joseph C. Salamone ,  Jay F. Kunzler ,  Richard M. Ozark

    IPC分类号： C07C69/52

    CPC分类号： C08F220/30 ,  C08F220/18 ,  C08F220/54 ,  G02B1/043 ,  C08L33/14

    摘要： A hydrophilic, aromatic-based monomer has an aromatic group substituted with at least one hydrophilic substituent and a reactive functional group. Polymers comprising such a hydrophilic, aromatic-based monomers avoid or reduce the risk of forming vacuoles of absorbed water. Furthermore, such polymers have high refractive index, and, thus, are advantageously used for making ophthalmic devices, such as intraocular lenses, contact lenses, corneal rings, corneal inlays, and keratoprostheses.

    摘要翻译： 亲水性芳香族单体具有被至少一个亲水取代基和反应性官能团取代的芳基。 包含这种亲水性芳族基单体的聚合物避免或降低形成吸收水的空泡的风险。 此外，这种聚合物具有高折射率，因此有利地用于制造眼科装置，例如眼内透镜，隐形眼镜，角膜环，角膜嵌体和角膜假体。

    High refractive-index, hydrophilic, arylsiloxy-containing macromonomers and polymers, and ophthalmic devices comprising such polymers
    66.
    发明授权
    High refractive-index, hydrophilic, arylsiloxy-containing macromonomers and polymers, and ophthalmic devices comprising such polymers 失效
    高折射率，亲水性，含芳基甲硅烷氧基的大分子单体和聚合物，以及包含这种聚合物的眼科装置

    公开(公告)号：US07297160B2

    公开(公告)日：2007-11-20

    申请号：US11153674

    申请日：2005-06-15

    申请人： Joseph C. Salamone ,  Jay F. Kunzler ,  Richard M. Ozark

    发明人： Joseph C. Salamone ,  Jay F. Kunzler ,  Richard M. Ozark

    IPC分类号： A61F2/16 ,  C08F30/08

    CPC分类号： C08G77/38 ,  C08G77/20 ,  G02B1/043 ,  Y10S525/937 ,  C08L83/04

    摘要： Hydrophilic, arylsiloxy-containing macromonomers have at least a terminal hydrophilic group attached to an arylsiloxy group. The aryl groups attached to siloxy groups can be substituted with other hydrophilic groups. Polymers comprising such hydrophilic, arylsiloxy-containing macromonomers avoid or reduce the risk of forming vacuoles of absorbed water. Furthermore, such polymers have high refractive index, and, thus, are advantageously used for making ophthalmic devices, such as intraocular lenses, contact lenses, corneal rings, corneal inlays, and keratoprostheses.

    摘要翻译： 亲水性，芳基甲硅烷氧基的大分子单体具有至少一个与芳基甲硅烷氧基连接的亲水基团。 连接到甲硅烷氧基的芳基可以被其它亲水基取代。 包含这种亲水的含芳基甲硅烷氧基的大分子单体的聚合物避免或降低形成吸收水的空泡的风险。 此外，这种聚合物具有高折射率，因此有利地用于制造眼科装置，例如眼内透镜，隐形眼镜，角膜环，角膜嵌体和角膜假体。

    Silicone hydrogel contact lenses
    67.
    发明授权
    Silicone hydrogel contact lenses 失效
    硅胶水凝胶隐形眼镜

    公开(公告)号：US07268198B2

    公开(公告)日：2007-09-11

    申请号：US11087150

    申请日：2005-03-23

    申请人： Jay F. Kunzler ,  David E. Seelye

    发明人： Jay F. Kunzler ,  David E. Seelye

    IPC分类号： C08F30/08

    CPC分类号： G02B1/043 ,  C08F226/10 ,  C08F230/08 ,  C08F283/122 ,  C08F290/148 ,  C08G77/24 ,  C08L51/085 ,  C08L83/10

    摘要： Silicone hydrogels, including vinyl carbonate endcapped polysiloxanes containing a fluorinated side chain, are useful as biomaterials, especially hydrogel biomaterials, including contact lens materials. The hydrogels are the hydrated polymerization product of a monomer mixture comprising a hydrophilic monomer and a polysiloxane-containing monomer, have an oxygen permeability of at least about 120 Barrers, a water content of at least about 20 weight percent, and a modulus no greater than about 83 g/mm2.

    摘要翻译： 包括含有氟化侧链的碳酸酯封端的聚硅氧烷的硅氧烷水凝胶可用作生物材料，特别是水凝胶生物材料，包括隐形眼镜材料。 水凝胶是包含亲水性单体和含聚硅氧烷的单体的单体混合物的水合聚合产物，其透氧度至少为约120巴勒，水含量为至少约20重量％，模量不大于 约83g / mm 2。

    SILOXANE PREPOLYMER CONTAINING PENDANT AND END-CAPPING CATIONIC AND POLYMERIZABLE GROUPS
    68.
    发明申请
    SILOXANE PREPOLYMER CONTAINING PENDANT AND END-CAPPING CATIONIC AND POLYMERIZABLE GROUPS 有权
    含有底物和端基的阳离子和聚合物组合物的硅氧烷预聚物

    公开(公告)号：US20070160649A1

    公开(公告)日：2007-07-12

    申请号：US11565151

    申请日：2006-11-30

    申请人： Derek A. Schorzman ,  Joseph C. Salamone ,  Jay F. Kunzler

    发明人： Derek A. Schorzman ,  Joseph C. Salamone ,  Jay F. Kunzler

    IPC分类号： C08F230/08 ,  C07F7/10

    CPC分类号： C08G77/388 ,  C08G77/452 ,  G02B1/043

    摘要： The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic random copolymers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymer compositions comprise siloxane prepolymer containing pendant and end-capping cationic and polymerizable groups.

    摘要翻译： 本发明涉及可用于制造生物相容性医疗器械的聚合物组合物。 更具体地，本发明涉及能聚合形成具有用于制造眼科装置的理想物理特性的聚合物组合物的某些阳离子无规共聚物。 这些性质包括用水提取聚合的医疗装置的能力。 这避免了使用本领域典型的有机溶剂。 聚合物组合物包含含有侧基和封端阳离子和可聚合基团的硅氧烷预聚物。