公开(公告)号：US20110192975A1

公开(公告)日：2011-08-11

申请号：US13012710

申请日：2011-01-24

Applicant: ZHONGWEI CHEN

Inventor： ZHONGWEI CHEN

IPC: G21K7/00

CPC classification number: H01J37/28 ,  H01J37/09 ,  H01J37/15 ,  H01J2237/0453 ,  H01J2237/0458

Abstract: A selectable Coulomb aperture in charged particle system comprises a non-magnetic conductive plate with a plurality of holes therein. The plurality of holes has variant sizes or diameters to select different beam currents of primary beam in the charged particle system. The charged particle system may include a charged particle source for emitting a primary beam, a condenser lens for receiving the primary beam and condensing the primary beam, an objective lens for receiving the primary beam and focusing the primary beam on a surface of a specimen. The selectable Coulomb aperture is positioned between the charged particle source and the condenser lens.

Abstract translation: 带电粒子系统中的可选择的库仑孔径包括其中具有多个孔的非磁性导电板。 多个孔具有不同的尺寸或直径，以在带电粒子系统中选择主波束的不同束流。 带电粒子系统可以包括用于发射主光束的带电粒子源，用于接收主光束并聚光主光束的聚光透镜，用于接收主光束并将主光束聚焦在样本表面上的物镜。 可选择的库仑孔位于带电粒子源和聚光透镜之间。

公开(公告)号：US07825386B2

公开(公告)日：2010-11-02

申请号：US11923012

申请日：2007-10-24

Applicant: Xuedong Liu ,  Xu Zhang ,  Joe Wang ,  Edward Tseng ,  Zhongwei Chen

Inventor： Xuedong Liu ,  Xu Zhang ,  Joe Wang ,  Edward Tseng ,  Zhongwei Chen

IPC: H01J37/244

CPC classification number: H01J37/145 ,  H01J37/28 ,  H01J2237/0475 ,  H01J2237/12 ,  H01J2237/14 ,  H01J2237/24485 ,  H01J2237/2807

Abstract: System and method for charged particle beam. According an embodiment, the present invention provides a charged particle beam apparatus. The apparatus includes a charged particle source for generating a primary charged particle beam. The apparatus also includes at least one condenser lens for pre-focusing the primary charge particle beam. Furthermore, the apparatus includes a compound objective lens for forming the magnetic field and the electrostatic field to focus the primary charged particle beam onto a specimen in the charged particle beam path. The specimen includes a specimen surface. The compound objective lens includes a conical magnetic lens, an immersion magnetic lens, and an electrostatic lens, the conical magnetic lens including an upper pole piece, a shared pole piece being electrically insulated from the upper pole piece, and an excitation coil.

Abstract translation: 带电粒子束的系统和方法。 根据实施例，本发明提供一种带电粒子束装置。 该装置包括用于产生初级带电粒子束的带电粒子源。 该装置还包括用于预聚焦初级充电粒子束的至少一个聚光透镜。 此外，该装置包括用于形成磁场的复合物镜和静电场，以将初级带电粒子束聚焦到带电粒子束路径中的样本上。 样品包括样品表面。 复合物镜包括锥形磁性透镜，浸没式磁透镜和静电透镜，该圆锥形磁性透镜包括上极片，与上极片电绝缘的共用极片和励磁线圈。

公开(公告)号：US20050249698A1

公开(公告)日：2005-11-10

申请号：US10526028

申请日：2002-09-16

Applicant: Zhihui Liu ,  Dafu Cui ,  Zhongwei Chen ,  Deyuan Shi ,  Yi Lu

Inventor： Zhihui Liu ,  Dafu Cui ,  Zhongwei Chen ,  Deyuan Shi ,  Yi Lu

IPC: A61K38/18 ,  A61K38/19 ,  A61P37/00 ,  C07K14/51 ,  A61K38/08 ,  A61K38/10

CPC classification number: C07K14/51 ,  A61K38/1709 ,  A61K38/1816 ,  A61K38/193 ,  A61K38/2013 ,  A61K2300/00

Abstract: The present inventions provides a pharmaceutical composition comprising a safe and efficient amount of OGP, a safe and efficient amount of G-CSF and a pharmaceutically acceptable carrier, wherein the molar ratio of OGP to G-CSF is from 0.25:1 to 100:1. According to the present invention, there is a good synergism between OGP and G-CSF. Thus the haematogenesis of G-CSF is greatly promoted. The invention also discloses the preparation method and usage of the pharmaceutical composition, especially in promoting the haematogenesis of G-CSF and the immune response of lymphocyte.

Abstract translation: 本发明提供了包含安全有效量的OGP，安全有效量的G-CSF和药学上可接受的载体的药物组合物，其中OGP与G-CSF的摩尔比为0.25:1至100:1 。 根据本发明，OGP与G-CSF之间存在良好的协同作用。 因此，G-CSF的血液发生得到极大的促进。 本发明还公开了药物组合物的制备方法和用途，特别是促进G-CSF的血液发生和淋巴细胞的免疫应答。

公开(公告)号：US11848169B1

公开(公告)日：2023-12-19

申请号：US18157817

申请日：2023-01-21

Applicant: Dazhi Chen ,  Zhongwei Chen

Inventor： Dazhi Chen ,  Zhongwei Chen

IPC: H01J1/304

CPC classification number: H01J1/3044 ,  H01J2201/30415 ,  H01J2201/30426 ,  H01J2201/30496

Abstract: A field-emission type electron source includes (i) a single-crystal tungsten rod having a sharpened terminus and (ii) a mass of ZrO formed only on a portion of the surface, or the entire surface, of the sharpened terminus. In preferred design, the single-crystal tungsten rod is placed in a gaseous medium that consists of oxygen and a non-oxygen gas. The molar ratio between oxygen and the non-oxygen gas is greater than 1:1.

公开(公告)号：US20220115204A1

公开(公告)日：2022-04-14

申请号：US17644789

申请日：2021-12-17

Applicant: Zhongwei Chen ,  Xiaoming Chen ,  Daniel Tang ,  Liang-Fu Fan

Inventor： Zhongwei Chen ,  Xiaoming Chen ,  Daniel Tang ,  Liang-Fu Fan

IPC: H01J37/26 ,  H01J37/244 ,  B08B7/00

Abstract: The present invention provides an apparatus of charged-particle beam e.g. an electron microscope comprising an in-column plasma generator for selectively cleaning BSE detector and BF/DF detector. In various embodiments, the plasma generator is located between a lower pole piece of objective lens and the BF/DF detectors, but outside trajectory area of the charged-particles from the sample stage to the BF/DF detector. Cleaning decomposed biological samples or contaminants on the surface of the detectors frequently and selectively with in-situ generated plasma can prevent the detectors from performance deterioration such as losing resolution and contrast in imaging at high levels of magnification.

公开(公告)号：US20220108869A1

公开(公告)日：2022-04-07

申请号：US17444192

申请日：2021-08-01

Applicant: Zhongwei Chen ,  Xiaoming Chen ,  Daniel Tang ,  Liang-Fu Fan

Inventor： Zhongwei Chen ,  Xiaoming Chen ,  Daniel Tang ,  Liang-Fu Fan

IPC: H01J37/28 ,  H01J37/20 ,  H01J37/317 ,  H01J37/141

Abstract: The present invention provides a driving system comprising two actuators for moving a stage through two elastic connectors; and a general apparatus/device comprising such a driving system, such as a machine tool, an analytical instrument, an optical microscope, and an apparatus of charged-particle beam such as electron microscope and an electron beam lithographical apparatus. When used in an electron microscope, the stage can be used as a specimen stage or a plate having apertures for electron beam to pass through. The novel stage driving system exhibits numerous technical merits such as simpler structure, better manufacturability, improved cost-effectiveness, and higher reliability, among others.

公开(公告)号：US20210296634A1

公开(公告)日：2021-09-23

申请号：US17267390

申请日：2019-08-09

Applicant: Janak Handa ,  Zhongwei Chen

Inventor： Zhongwei CHEN ,  Ali GHORBANI KASHKOOLI ,  Sepehr KHAZRAEI

IPC: H01M4/136 ,  H01M10/36 ,  H01M4/66 ,  H01M4/38 ,  H01M4/74 ,  H01M4/04 ,  H01M4/1397 ,  H01M4/1391 ,  H01M4/505 ,  H01M4/58 ,  H01M4/131

Abstract: A battery cell and method for manufacturing the same are provided. The battery cell includes a binder-free dough-like cathode separated from a sponge zinc anode by a separator and a hybrid aqueous electrolyte.

公开(公告)号：US20190051908A1

公开(公告)日：2019-02-14

申请号：US15762417

申请日：2016-09-23

Applicant: Zhongwei CHEN ,  Hao LIU

Inventor： Zhongwei CHEN ,  Hao LIU

IPC: H01M4/86 ,  H01M12/08 ,  H01M2/02

Abstract: A rechargeable horizontally configured tri-electrode single flow zinc-air battery with a floating cathode, which is theoretically capable of providing unlimited cycle life is provided. The tri-electrode configuration consists of one anode and two cathodes, one for charging and one for discharging. The charge cathode may comprise a water permeable alkaline resisting metal/mesh foam, which avoids carbon corrosion. The floating discharge cathode comprises an air permeable and water permeable catalytic oxygen reduction electrode, which eliminates or reduces the blockage of air tunnels. The anode comprises an inert, conductive electrode allowing for zinc deposition during battery charging and zinc dissolving during battery discharging. The flowing electrolyte removes zinc ions from the anode preventing or minimizing the formation of zinc oxides during discharging and cleans the anode after each full discharge. The horizontal configuration further eliminates or reduces electrolyte leakage.

公开(公告)号：US20180013138A1

公开(公告)日：2018-01-11

申请号：US15548549

申请日：2016-02-05

Applicant: Zhongwei CHEN ,  Aiping YU ,  Fathy Mohamed Hassan

Inventor： Zhongwei CHEN ,  Aiping YU ,  Fathy Mohamed Hassan

IPC: H01M4/36 ,  H01M4/66 ,  H01M4/62 ,  H01M4/583 ,  H01M4/1397 ,  H01M4/136 ,  H01M10/0525 ,  H01M4/04

Abstract: A method for preparing an electrode for use in lithium batteries and the resulting electrodes are described The method comprises coating a slurry of silicon, sulfur doped graphene and polyacrylonitrile on a current collector followed by sluggish heat treatment.

公开(公告)号：US09527745B2

公开(公告)日：2016-12-27

申请号：US14654215

申请日：2013-12-20

Applicant: Aiping Yu ,  Victor Chabot ,  Zhongwei Chen

Inventor： Aiping Yu ,  Victor Chabot ,  Zhongwei Chen

IPC: C01B31/04

CPC classification number: C01B31/0469 ,  C01B32/19 ,  C01B2204/02 ,  C01B2204/04

Abstract: A method of producing single or few-layer graphene comprises exfoliating graphite with a polymer to form a graphene-polymer composite and subsequently treating the composite to disassociate graphene. The exfoliation process is conducted using sonication. The graphene is disassociated from the polymer by a treatment step such as acid hydrolysis. The method results in highly pure graphene.

Abstract translation: 生产单层或几层石墨烯的方法包括用聚合物去除石墨以形成石墨烯 - 聚合物复合材料，随后处理复合材料以分离石墨烯。 剥离过程使用超声处理进行。 石墨烯通过诸如酸水解的处理步骤与聚合物分离。 该方法产生高纯度石墨烯。