公开(公告)号：US08430887B2

公开(公告)日：2013-04-30

申请号：US12112477

申请日：2008-04-30

申请人： Csaba Truckai ,  John H. Shadduck ,  Robert Luzzi

发明人： Csaba Truckai ,  John H. Shadduck ,  Robert Luzzi

IPC分类号： A61B17/58 ,  A61B17/60 ,  A61F2/00

CPC分类号： A61B17/8822 ,  A61B17/88 ,  A61B17/8805 ,  A61B17/8811 ,  A61B17/8816 ,  A61B17/8836

摘要： Systems and methods for treating bone, such as vertebral compression fractures are disclosed. A method includes controllably applying energy to a bone cement volume outside of a patient's body to selectively accelerate the polymerization rate of the bone fill material volume prior to introduction into a bone. The method further includes sequentially introducing a plurality of cement carrying structures with the accelerated polymerization rate bone cement volume into the bone. A system for use in the method includes at least one elongated cement-carrying structure sized to carry a bone cement volume therein and an energy source operatively coupleable to the cement-carrying structure. The energy source applies energy to the bone cement volume to selectively accelerate a polymerization rate thereof. An elongated injector insertable into the bone has a passageway that removably receives the elongated cement-carrying structure to allow delivery of the accelerated polymerization rate bone cement into the bone.

公开(公告)号：US20120303036A1

公开(公告)日：2012-11-29

申请号：US13488183

申请日：2012-06-04

申请人： Csaba Truckai ,  John H. Shadduck ,  Robert Luzzi

发明人： Csaba Truckai ,  John H. Shadduck ,  Robert Luzzi

IPC分类号： A61B17/58

CPC分类号： A61B17/8836 ,  A61B17/864 ,  A61B2017/00022 ,  A61B2017/00026 ,  A61B2017/00084 ,  A61F2/44

摘要： The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of fill material introduced into cancellous bone. A method of treating bone includes injecting a volume of fill material into a bone and selectively modifying a viscosity of the bone filler to control the direction of flow of the fill material within the bone. A system for treating bone using this method includes an introducer for delivering fill material into the bone and an energy source selectively coupleable to the fill material to alter the viscosity of the fill material via an energy emitter.

摘要翻译： 本发明在某些实施例中涉及用于治疗诸如椎体压缩性骨折的骨整形术程序的医疗装置。 更具体地，本发明的实施例涉及通过控制引入松质骨的填充材料的几何形状来可控地恢复椎体高度的仪器和方法。 治疗骨的方法包括将一定体积的填充材料注入骨骼中，并选择性地改变骨填充物的粘度以控制骨中填充材料的流动方向。 使用这种方法治疗骨骼的系统包括用于将填充材料输送到骨骼中的导引器和能够选择性地与填充材料耦合的能量源，以经由能量发射器改变填充材料的粘度。

公开(公告)号：US20120239049A1

公开(公告)日：2012-09-20

申请号：US13305501

申请日：2011-11-28

申请人： Csaba Truckai ,  John H. Shadduck

发明人： Csaba Truckai ,  John H. Shadduck

IPC分类号： A61B17/58

CPC分类号： A61B17/8836 ,  A61B17/8811 ,  A61B17/8822 ,  A61B2017/00022 ,  A61B2017/00084 ,  A61B2090/064 ,  A61F2/44 ,  A61F2/4601

摘要： The present invention relates in certain embodiments to medical devices, systems and methods for use in osteoplasty procedures, such as vertebral compression fractures. One system for delivering a bone fill material to a bone includes an elongated introducer configured for insertion into a bone and having a channel sized to allow a flow of bone fill material therethrough. The introducer has at least one outlet opening in communication with the channel for delivering the bone fill material into the bone. A thermal energy emitter is coupled to the introducer and configured to apply thermal energy to the bone fill material flowing through the introducer. A hydraulic pressure source is operatively coupled to the introducer and configured to apply a force on the bone fill material to provide a pressurized flow of bone fill material through the introducer.

摘要翻译： 本发明在某些实施例中涉及用于骨成形术程序的医疗装置，系统和方法，例如椎体压缩性骨折。 用于将骨填充材料递送到骨骼的一种系统包括细长导引器，其构造成用于插入骨骼并且具有通道，其尺寸允许骨填充材料流过其中。 引导器具有与通道连通的至少一个出口开口，用于将骨填充材料输送到骨中。 热能发射器耦合到导引器并且构造成将热能施加到流过导引器的骨填充材料。 液压源可操作地联接到导引器并且构造成在骨填充材料上施加力以通过导引器提供加压的骨填充材料流。

公开(公告)号：US08241335B2

公开(公告)日：2012-08-14

申请号：US12729004

申请日：2010-03-22

申请人： Csaba Truckai ,  John H. Shadduck

发明人： Csaba Truckai ,  John H. Shadduck

IPC分类号： A61B17/88

CPC分类号： A61B17/32002 ,  A61B17/1615 ,  A61B17/1617 ,  A61B17/1631 ,  A61B17/1642 ,  A61B17/1668 ,  A61B17/1671 ,  A61B17/320725 ,  A61B2017/00261 ,  A61B2017/00557 ,  A61B2017/320004 ,  A61B2217/005 ,  A61B2217/007 ,  A61M1/0082

摘要： The invention provides instruments and methods for prophylactic treatment of an osteoporotic vertebral body or for treating a vertebral compression fracture (VCF). In one exemplary method, a probe system uses a high speed rotational elastomeric cutter having an optional expandable abrasive surface for abrading or cutting at least one path or region within vertebral cancellous bone. Irrigation and aspiration sources are included in the probe system for removing abraded bone debris. In one embodiment, the high speed rotational abrader uses a tissue-selective abrading surface that abrades or cuts bone but does not cut soft tissue. In another embodiment, an expandable abrading surface allows the treatment of bone with low pressures to create paths or spaces without explosive expansion forces known in prior art balloon procedures that are designed to crush and compact cancellous bone in a vertebra. After the creation of a path or space, an in-situ hardenable bone cement volume is introduced into each path or space to support the vertebra.

摘要翻译： 本发明提供了用于预防性治疗骨质疏松性椎体或用于治疗椎体压缩性骨折（VCF）的仪器和方法。 在一个示例性方法中，探针系统使用具有可选的可扩展研磨表面的高速旋转弹性体切割器，用于研磨或切割椎骨松质骨内的至少一个路径或区域。 用于清除磨损的骨碎片的探针系统中包含灌溉和吸入源。 在一个实施例中，高速旋转磨擦机使用磨损或切割骨骼而不切割软组织的组织选择性研磨表面。 在另一个实施方案中，可膨胀研磨表面允许用低压处理骨骼以产生路径或空间，而不会在现有技术的球囊过程中已知的爆炸膨胀力被设计成压缩和压紧椎骨中的松质骨。 在创建路径或空间之后，将原位可硬化的骨水泥体积引入到每个路径或空间中以支撑椎骨。

公开(公告)号：US20120138069A1

公开(公告)日：2012-06-07

申请号：US13311460

申请日：2011-12-05

申请人： Edward M. GILLIS ,  John H. Shadduck ,  Csaba Truckai

发明人： Edward M. GILLIS ,  John H. Shadduck ,  Csaba Truckai

IPC分类号： A61F5/56

CPC分类号： A61F5/566

摘要： An implant for treating an obstructive airway disorder includes an elongate implant body configured for implanting in airway-interface tissue. At least a portion of the elongate body carries a light transmission material for permitting light transmission therein. Systems and methods of treating an airway disorder comprising implanting an implant in an airway-interface tissue are also provided.

摘要翻译： 用于治疗阻塞性气道障碍的植入物包括构造成用于植入气道界面组织中的细长植入体。 细长体的至少一部分携带用于允许光透射的透光材料。 还提供了治疗气道障碍的系统和方法，包括将植入物植入气道界面组织中。

公开(公告)号：US08192442B2

公开(公告)日：2012-06-05

申请号：US12502163

申请日：2009-07-13

申请人： Csaba Truckai ,  John H. Shadduck ,  Robert Luzzi ,  Grace A. Carlson ,  C. Travis Rappleye

发明人： Csaba Truckai ,  John H. Shadduck ,  Robert Luzzi ,  Grace A. Carlson ,  C. Travis Rappleye

IPC分类号： A61B17/00 ,  A61F2/44

CPC分类号： A61B17/8836 ,  A61B17/864 ,  A61B2017/00022 ,  A61B2017/00026 ,  A61B2017/00084 ,  A61F2/44

摘要： The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of fill material introduced into cancellous bone. A method of treating bone includes injecting a volume of fill material into a bone and selectively modifying a viscosity of the bone filler to control the direction of flow of the fill material within the bone. A system for treating bone using this method includes an introducer for delivering fill material into the bone and an energy source selectively coupleable to the fill material to alter the viscosity of the fill material via an energy emitter in the introducer.

摘要翻译： 本发明在某些实施例中涉及用于治疗诸如椎体压缩性骨折的骨整形术程序的医疗装置。 更具体地，本发明的实施例涉及通过控制引入松质骨的填充材料的几何形状来可控地恢复椎体高度的仪器和方法。 治疗骨的方法包括将一定体积的填充材料注入骨骼中，并选择性地改变骨填充物的粘度以控制骨中填充材料的流动方向。 使用该方法治疗骨的系统包括用于将填充材料输送到骨中的导引器和能够选择性地与填充材料相连的能量源，以经由引入器中的能量发射器改变填充材料的粘度。

公开(公告)号：US08192428B2

公开(公告)日：2012-06-05

申请号：US12406914

申请日：2009-03-18

申请人： Csaba Truckai ,  John H. Shadduck

发明人： Csaba Truckai ,  John H. Shadduck

IPC分类号： A61B18/12

CPC分类号： A61B18/1492 ,  A61B18/1442 ,  A61B2018/00077 ,  A61B2018/00083 ,  A61B2018/00148 ,  A61B2018/00404 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00809 ,  A61B2090/064

摘要： An electrosurgical instrument and method for treating varicose veins. In one embodiment, an elongate catheter has a distal working end that carries an electrosurgical energy delivery surface comprising at least one electrode with a positive temperature coefficient of resistance (PTCR) surface and/or an electrode with a pressure sensitive variable resistance to provide a smart surface for controlling Rf current flow at the interface of electrosurgical surface and the tissue. The electrode surface then can limit or modulate Rf energy delivery through the surface in response to the temperature of the surface or the engagement pressure of the surface against the engaged tissue. In operation, the smart electrosurgical surface prevents arcing at the electrode-tissue interface, and thus controls ohmic heating to prevent tissue desiccation, charring and emboli formation.

摘要翻译： 一种用于治疗静脉曲张的电外科器械和方法。 在一个实施例中，细长导管具有远端工作端，其承载电外科能量输送表面，其包括具有正温度系数电阻（PTCR）表面的至少一个电极和/或具有压敏可变电阻的电极，以提供智能 用于控制电外科表面和组织界面处的Rf电流的表面。 电极表面然后可以响应于表面的温度或表面对接合的组织的接合压力而限制或调节通过表面的Rf能量传递。 在操作中，智能电外科表面防止电极 - 组织界面处的电弧，从而控制欧姆加热以防止组织干燥，炭化和栓塞形成。

公开(公告)号：US08163031B2

公开(公告)日：2012-04-24

申请号：US12942936

申请日：2010-11-09

申请人： Csaba Truckai ,  John H. Shadduck

发明人： Csaba Truckai ,  John H. Shadduck

IPC分类号： A61F2/28

CPC分类号： A61B17/7095 ,  A61B17/68 ,  A61B17/686 ,  A61F2/28 ,  A61F2/30965 ,  A61F2/3662 ,  A61F2/44 ,  A61F2002/2817 ,  A61F2002/2835 ,  A61F2002/30006 ,  A61F2002/30011 ,  A61F2002/30023 ,  A61F2002/30069 ,  A61F2002/3008 ,  A61F2002/30092 ,  A61F2002/30224 ,  A61F2002/30583 ,  A61F2002/30677 ,  A61F2002/3085 ,  A61F2002/30957 ,  A61F2002/30971 ,  A61F2210/0014 ,  A61F2210/0085 ,  A61F2230/0069 ,  A61F2250/0015 ,  A61F2250/0018 ,  A61F2250/0023 ,  A61F2250/0034 ,  A61F2250/0098 ,  A61F2310/00353 ,  A61L27/50 ,  A61L2430/02

摘要： A system and method for treating bone abnormalities including vertebral compression fractures and the like. In one method, an elastomeric composite implant body is inserted into bone. A rigid insert can be inserted into the elastomeric composite implant body. The elastomeric composite implant body can be deformed with the rigid insert to thereby form an interference fit between the bone and the implant.

摘要翻译： 一种用于治疗包括椎骨压缩性骨折等骨骼异常的系统和方法。 在一种方法中，将弹性体复合植入体插入骨中。 刚性插入件可插入到弹性体复合植入体中。 弹性体复合植入体可以用刚性插入物变形，从而在骨与植入物之间形成过盈配合。

公开(公告)号：US20110308529A1

公开(公告)日：2011-12-22

申请号：US13113933

申请日：2011-05-23

申请人： Edward M. Gillis ,  John H. Shadduck ,  Csaba Truckai ,  Andrew Poutiatine ,  Paul J. Buscemi

发明人： Edward M. Gillis ,  John H. Shadduck ,  Csaba Truckai ,  Andrew Poutiatine ,  Paul J. Buscemi

IPC分类号： A61F5/56

CPC分类号： A61F2/00 ,  A61F5/566 ,  A61F2210/0004

摘要： A system for treating an airway disorder is provided with an implant body configured to conform to an airway-interface tissue site in a manner compatible with normal physiological function of the site. In some embodiments, the implant body has a V-shape with first and second elongated legs configured for implantation in airway-interface tissue. The first and second elongated legs are configured to apply tensile forces to the tissue. Methods of using such systems are also provided.

摘要翻译： 一种用于治疗气道障碍的系统设置有植入体，其构造成以与该部位的正常生理功能相适应的方式与气道界面组织部位一致。 在一些实施例中，植入物本体具有V形，其中第一和第二细长腿构造成用于植入气道界面组织中。 第一和第二细长腿构造成对组织施加张力。 还提供了使用这种系统的方法。

公开(公告)号：US08066712B2

公开(公告)日：2011-11-29

申请号：US11469752

申请日：2006-09-01

申请人： Csaba Truckai ,  John H. Shadduck

发明人： Csaba Truckai ,  John H. Shadduck

IPC分类号： A61B17/00

CPC分类号： A61B17/8836 ,  A61B17/8811 ,  A61B17/8822 ,  A61B2017/00022 ,  A61B2017/00084 ,  A61B2090/064 ,  A61F2/44 ,  A61F2/4601

摘要： The disclosure relates in certain embodiments to medical devices, systems and methods for use in osteoplasty procedures, such as vertebral compression fractures. One system for delivering a bone fill material to a bone includes an elongated introducer configured for insertion into a bone and having a channel sized to allow a flow of bone fill material therethrough. The introducer has at least one outlet opening in communication with the channel for delivering the bone fill material into the bone. A thermal energy emitter is coupled to the introducer and configured to apply thermal energy to the bone fill material flowing through the introducer. A sensor and a computer controller can be used to measure data about the bone fill material and to control certain aspects of the flow of bone fill material. A hydraulic pressure source may also be operatively coupled to the introducer and configured to apply a force on the bone fill material to provide a pressurized flow of bone fill material through the introducer. In certain embodiments, the system for use in osteoplasty procedures can include a cooling system that can be used to cool the bone fill material.

摘要翻译： 在某些实施例中，本公开涉及用于骨成形术程序的医疗装置，系统和方法，例如椎体压缩性骨折。 一种用于将骨填充材料递送到骨骼的系统包括细长导引器，其构造成用于插入骨骼并且具有通道，其尺寸允许骨填充材料流过其中。 引导器具有与通道连通的至少一个出口开口，用于将骨填充材料输送到骨中。 热能发射器耦合到导引器并且构造成将热能施加到流过导引器的骨填充材料。 可以使用传感器和计算机控制器来测量关于骨填充材料的数据并且控制骨填充材料的流动的某些方面。 液压源还可以可操作地联接到导引器并且构造成在骨填充材料上施加力以通过导引器提供加压的骨填充材料流。 在某些实施例中，用于成骨术程序的系统可以包括可用于冷却骨填充材料的冷却系统。