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92 条记录 (耗时 0.033 秒)

    Cyclic, cystein-free protein
    61.
    发明授权
    Cyclic, cystein-free protein 有权
    循环，半胱氨酸蛋白

    公开(公告)号：US08501679B2

    公开(公告)日：2013-08-06

    申请号：US12747723

    申请日：2008-12-12

    申请人： Bernhard Fischer ,  Rudolf Lucas

    发明人： Bernhard Fischer ,  Rudolf Lucas

    IPC分类号： A61K38/00

    CPC分类号： A61K38/191 ,  C07K14/525

    摘要： A protein selected from the amino acid sequence of the region valine Val(91) to glycine Gly(121) of the mature human tumor necrosis factor, or a portion thereof, with the proviso that the protein comprises at least the amino acid sequence of the region lysine Lys(98) to glutamic acid Glu(116), with the cysteine Cys(101) being replaced by a glycine and an amide bond being formed between the amino group of the side chain of the lysine Lys(98) and the carboxyl group of the side chain of the glutamic acid Glu(116), which activates epithelial ion channels and improves the lung function and which can be used for the manufacture of medicaments for the treatment of diseases associated with the lung function, such as oedemas.

    摘要翻译： 选自成熟人肿瘤坏死因子的缬氨酸Val（91）至甘氨酸Gly（121）的氨基酸序列的蛋白质或其部分，条件是蛋白质至少包含氨基酸序列 区域赖氨酸Lys（98）至谷氨酸Glu（116），半胱氨酸Cys（101）被赖氨酸Lys（98）侧链的氨基与羧基之间形成的甘氨酸和酰胺键所取代 谷氨酸Glu（116）的侧链基团，其激活上皮离子通道并改善肺功能，并且其可用于制备用于治疗与肺功能相关的疾病如药物的药物。

    Staged modular hydrocarbon reformer with internal temperature management
    62.
    发明申请
    Staged modular hydrocarbon reformer with internal temperature management 审中-公开
    具有内部温度管理的分段模块化烃重整器

    公开(公告)号：US20070227070A1

    公开(公告)日：2007-10-04

    申请号：US11395672

    申请日：2006-03-31

    申请人： Bernhard Fischer ,  Diane England

    发明人： Bernhard Fischer ,  Diane England

    IPC分类号： B01J8/00

    CPC分类号： B01J19/2485 ,  B01J19/249 ,  B01J2219/0004 ,  B01J2219/2453 ,  B01J2219/2459 ,  B01J2219/2479 ,  C01B3/382 ,  C01B3/386 ,  C01B2203/0261 ,  C01B2203/1023 ,  C01B2203/1047 ,  C01B2203/1058 ,  C01B2203/1082 ,  C01B2203/1094 ,  C01B2203/1235 ,  C01B2203/143 ,  Y02P20/52

    摘要： A CPOx hydrocarbon reformer comprising a plurality of sequential reforming stages for generating reformate. The first stage comprises adjacent active and inactive flow channels. Only a portion of the surface is provided with catalyst. The active channels have low catalytic activity such that about one-quarter of the reactants passing through the first stage is catalyzed. Reactants flowing through the inactive channels cool the active channels, preventing bed erosion. The fast exothermic combustion reaction near the front edge of the catalyst produces largely water and carbon dioxide but little hydrogen. Endothermic reactions in the following stages produce hydrogen and carbon monoxide while consuming water, carbon dioxide, and the remaining hydrocarbon fuel and oxygen using steam- and dry-reforming. Preferably, the intermediate stage reacts about one-half of the fuel. The last stage is fully coated to react the remainder of the fuel, and catalyst activity is increased.

    摘要翻译： 一种CPOx烃重整器，包括用于产生重整产物的多个连续重整级。 第一级包括相邻的主动和不活动的流动通道。 只有一部分表面设有催化剂。 活性通道具有低催化活性，使得通过第一阶段的约四分之一的反应物被催化。 流过非活动通道的反应物冷却活性通道，防止床层侵蚀。 催化剂前缘附近的快速放热燃烧反应主要产生水和二氧化碳，但几乎没有氢气。 以下阶段的吸热反应产生氢气和一氧化碳，同时使用蒸汽和干式重整方式消耗水，二氧化碳和剩余的烃燃料和氧气。 优选地，中间阶段反应大约一半的燃料。 最后一个阶段被完全涂覆以反应剩余的燃料，催化剂活性增加。

    Avoidance of poisoning during anesthesia
    63.
    发明授权
    Avoidance of poisoning during anesthesia 有权
    麻醉期间避免中毒

    公开(公告)号：US07002678B1

    公开(公告)日：2006-02-21

    申请号：US10069892

    申请日：1999-08-28

    申请人： Bernhard Fischer

    发明人： Bernhard Fischer

    IPC分类号： G01J3/44

    CPC分类号： A61M16/01 ,  A61M16/104 ,  A61M2016/102 ,  A61M2230/43 ,  G01N21/65 ,  G01N2021/651

    摘要： For avoiding poisoning effects during anesthesia, the quantitative amount of an anesthetic agent degradation product, preferably carbon monoxide CO and/or trifluoromethane CHF3, in an anesthetic gas mixture is determined. When the determined quantitative amount of the anesthetic agent degradation product in the anesthetic gas mixture exceeds a given threshold, an alarm is provided. This is preferably accomplished by measuring a Raman spectrum of the gas mixture, and determining the quantitative amount of the anesthetic agent degradation product in the gas mixture by comparing the measured Raman spectrum with a reference spectrum of the anesthetic agent degradation product.

    摘要翻译： 为了避免麻醉期间的中毒作用，测定麻醉剂气体混合物中麻醉剂降解产物，优选一氧化碳CO和/或三氟甲烷CHF 3 3的定量。 当麻醉剂混合物中麻醉剂降解产物的确定量超过给定阈值时，提供警报。 这优选通过测量气体混合物的拉曼光谱，并通过将测量的拉曼光谱与麻醉剂降解产物的参考光谱进行比较来确定气体混合物中麻醉剂降解产物的定量。

    Ultra low Nox emissions combustions system for gas turbine engines
    66.
    发明申请
    Ultra low Nox emissions combustions system for gas turbine engines 有权
    用于燃气轮机的超低NOx排放燃烧系统

    公开(公告)号：US20050103023A1

    公开(公告)日：2005-05-19

    申请号：US10620295

    申请日：2003-07-16

    申请人： Bernhard Fischer

    发明人： Bernhard Fischer

    IPC分类号： F23C13/02 ,  F23R3/36 ,  F23R3/40

    CPC分类号： F23R3/40 ,  F23C13/02 ,  F23N2037/10 ,  F23N2037/12 ,  F23R3/36

    摘要： A combustion system for a gas turbine engine includes a Catalyst (CAT) combustion sub-system for generating combustion products under a lean premixed fuel/air condition in the presence of a Catalyst and a Dry-Low-Emissions (DLE) combustion sub-system, for generating combustion products under a lean premixed fuel/air condition. Gaseous and liquid fuels are used for the DLE combustion sub-system while only gaseous fuel is used for the CAT combustion system. The engine operates at start-up and under low load conditions with the DLE combustion system and switches over the combustion process to the CAT combustion sub-system under high load conditions. Thus the combustion system according to the invention combines the advantages of DLE and CAT combustion processes so that the gas turbine engine operates over an entire operating range thereof at high engine efficiency while minimizing omissions of nitrogen oxides and carbon monoxide from the engine.

    摘要翻译： 用于燃气涡轮发动机的燃烧系统包括催化剂（CAT）燃烧子系统，用于在催化剂和干 - 低排放（DLE）燃烧子系统的存在下，在贫燃混合燃料/空气条件下产生燃烧产物 用于在贫燃混合燃料/空气条件下产生燃烧产物。 气体和液体燃料用于DLE燃烧子系统，而只有气体燃料用于CAT燃烧系统。 发动机在启动和低负载条件下使用DLE燃烧系统运行，并在高负载条件下将燃烧过程切换到CAT燃烧子系统。 因此，根据本发明的燃烧系统结合了DLE和CAT燃烧过程的优点，使得燃气涡轮发动机在高发动机效率下在其整个工作范围内运行，同时最小化来自发动机的氮氧化物和一氧化碳的遗漏。

    Ultra low NOx emissions combustion system for gas turbine engines
    68.
    发明授权
    Ultra low NOx emissions combustion system for gas turbine engines 有权

    公开(公告)号：US06532743B1

    公开(公告)日：2003-03-18

    申请号：US09843753

    申请日：2001-04-30

    申请人： Bernhard Fischer

    发明人： Bernhard Fischer

    IPC分类号： F23R340

    CPC分类号： F23C13/02 ,  F23R3/34 ,  F23R3/36 ,  F23R3/40

    摘要： A combustion system for a gas turbine engine includes a Catalyst (CAT) combustion sub-system for generating combustion products under a lean premixed fuel/air condition in the presence of a Catalyst and a Dry-Low-Emissions (DLE) combustion sub-system, for generating combustion products under a lean premixed fuel/air condition. Gaseous and liquid fuels are used for the DLE combustion sub-system while only gaseous fuel is used for the CAT combustion system. The engine operates at start-up and under low load conditions with the DLE combustion system and switches over the combustion process to the CAT combustion sub-system under high load conditions. Thus the combustion system according to the invention combines the advantages of DLE and CAT combustion processes so that the gas turbine engine operates over an entire operating range thereof at high engine efficiency while minimizing emissions of nitrogen oxides and carbon monoxide from the engine.