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    Intravascular flow modifier and reinforcement device
    63.
    发明授权
    Intravascular flow modifier and reinforcement device 失效
    血管内流量调节器和加强装置

    公开(公告)号：US06878163B2

    公开(公告)日：2005-04-12

    申请号：US10712887

    申请日：2003-11-12

    申请人： Andrew J. Denardo ,  David A. Ferrera ,  Peter Wilson ,  Lok A. Lei

    发明人： Andrew J. Denardo ,  David A. Ferrera ,  Peter Wilson ,  Lok A. Lei

    IPC分类号： A61B17/00 ,  A61B17/12 ,  A61B17/22 ,  A61F2/00 ,  A61F2/01 ,  A61F2/88 ,  A61F2/90 ,  A61L27/00 ,  A61L31/00 ,  A61F2/06

    CPC分类号： A61F2/01 ,  A61B17/12022 ,  A61B17/12118 ,  A61B17/12172 ,  A61B17/1219 ,  A61F2/07 ,  A61F2/88 ,  A61F2/885 ,  A61F2/90 ,  A61F2002/016 ,  A61F2002/072 ,  A61F2210/0014 ,  A61F2230/0013 ,  A61F2230/0071 ,  A61F2230/0091 ,  A61F2250/0036 ,  A61F2250/0037 ,  B21F45/008

    摘要： An intravascular flow modifier and vascular reinforcement for treatment of aneurysms is formed of one or more loops of wire of resilient material formed into a series of transverse loops and longitudinal connecting sections to configure an essentially cylindrical reinforcement device that still allows, if desired, access to the neck of an aneurysm for insertion of embolic coils and the like. The proximal and distal regions of the sinusoidal loops may be more tightly coiled than the intermediate regions of the loops, or may have a larger diameter than the intermediate regions. The intravascular flow modifier and vascular reinforcement device can be provided with an outer covering that can be formed as a fiber, and can be woven, or can be formed as a ribbon wound about the intravascular flow modifier and vascular reinforcement device. The wire of resilient material can also be coated with a hydrophilic material. One or more round or oval intermediate loops extending radially outward may also be provided. An apparatus for removing clots may also be formed from one or more loops of wire of resilient material in a hollow conical shape non-detachably joined to a deployment device, to trap and hold clots within a vessel.

    摘要翻译： 用于治疗动脉瘤的血管内流动改善剂和血管增强剂由形成为一系列横向环和纵向连接部分的一个或多个弹性材料线的一个或多个环形成，以构造基本上圆柱形的加强装置，如果需要，其还允许进入 用于插入栓塞线圈的动脉瘤的颈部等。 正弦曲线的近端和远端区域可以比环路的中间区域更紧密地盘绕，或者可以具有比中间区域更大的直径。 血管内流动改性剂和血管加强装置可以设置有可以形成为纤维的外覆盖层，并且可以被编织，或者可以形成为卷绕在血管内流动改性剂和血管加强装置周围的带状物。 弹性材料的丝线也可以用亲水材料涂覆。 还可以设置一个或多个径向向外延伸的圆形或椭圆形中间环。 用于除去凝块的装置也可以由一个或多个中空圆锥形的弹性材料线的一个或多个环形成，其不可拆卸地连接到展开装置，以将血块捕获并保持在容器内。

    Clot retrieval device
    65.
    发明授权
    Clot retrieval device 有权
    凝块检索装置

    公开(公告)号：US06692504B2

    公开(公告)日：2004-02-17

    申请号：US10023028

    申请日：2001-12-17

    申请人： Daniel R. Kurz ,  David A. Ferrera

    发明人： Daniel R. Kurz ,  David A. Ferrera

    IPC分类号： A61B1722

    CPC分类号： A61B17/22031 ,  A61B17/221 ,  A61B2017/00867 ,  A61B2017/00871 ,  A61B2017/22034 ,  A61B2017/2217

    摘要： A shape memory clot retrieval device which can be placed in the vasculature of a patient for retrieving and removing distal clots. The clot retrieval device has an elongated catheter member that can be inserted in the vasculature, with one or more clot retrieval members on the elongated catheter member that are movable between an initial compressed configuration in which the clot retrieval device is inserted into the vasculature and an expanded configuration extending outwardly from the elongated catheter member to trap and hold clots within the vessel. The clot retrieval device typically can be introduced to the desired treatment site in the vasculature through a guiding catheter.

    摘要翻译： 形状记忆凝块取出装置，其可以放置在患者的脉管系统中，用于检索和去除远端血块。 凝块取出装置具有细长的导管构件，该导管构件可以插入脉管系统中，细长的导管构件上的一个或多个凝块取回构件可以在其中凝块取出装置插入脉管系统的初始压缩构型和 扩张构型从细长的导管构件向外延伸以将血块捕获并保持在血管内。 凝块回收装置通常可以通过引导导管引入脉管系统中的期望的治疗部位。

    Dilatation catheter balloon made from PEN based homopolymer or random copolymer
    66.
    发明授权
    Dilatation catheter balloon made from PEN based homopolymer or random copolymer 有权
    由PEN基均聚物或无规共聚物制成的扩张导管球囊

    公开(公告)号：US06585688B2

    公开(公告)日：2003-07-01

    申请号：US10045554

    申请日：2002-01-14

    申请人： David A. Ferrera ,  Ronald a. Sahatjian ,  Andrew J. Campbell ,  George C. Michaels

    发明人： David A. Ferrera ,  Ronald a. Sahatjian ,  Andrew J. Campbell ,  George C. Michaels

    IPC分类号： A61M2900

    CPC分类号： A61L29/049 ,  A61L29/06 ,  A61M25/10 ,  Y10T428/1334 ,  Y10T428/1352 ,  C08L67/02

    摘要： A balloon for a medical device has a structural layer of a highly crystallized PEN polymer material. The PEN polymer material a polyethylene naphthalate homopolymer or a crystallizable copolyester made up of residues of ethylene glycol, naphthalene dicarboxylic acid (NDC) and at least one member of the group (PA) consisting of terephthalic acid and isophthalic acid. The NDC groups make up about 5% or more of the sum of NDC and PA groups in the copolymer. The balloon is characterized by an ability to withstand a hoop stress of at least 35,000 psi without bursting.

    摘要翻译： 用于医疗装置的气囊具有高度结晶的PEN聚合物材料的结构层。 PEN聚合物材料是聚萘二甲酸乙二醇酯均聚物或由乙二醇，萘二甲酸（NDC）和由对苯二甲酸和间苯二甲酸组成的组（PA）的至少一个成员的残基组成的可结晶共聚酯。 NDC组在共聚物中占NDC和PA基团的总和的约5％以上。 气球的特征在于能够承受至少35,000psi的环向应力而不发生爆裂。

    Variable stiffness electrically conductive composite, resistive heating catheter shaft
    67.
    发明授权
    Variable stiffness electrically conductive composite, resistive heating catheter shaft 有权
    可变刚度导电复合材料，电阻加热导管轴

    公开(公告)号：US06562021B1

    公开(公告)日：2003-05-13

    申请号：US09608497

    申请日：2000-06-30

    申请人： J. Todd Derbin ,  David A. Ferrera

    发明人： J. Todd Derbin ,  David A. Ferrera

    IPC分类号： A61M2500

    CPC分类号： G02B23/26 ,  A61B18/14 ,  A61B18/24 ,  A61M25/0009 ,  A61M25/0045 ,  A61M25/0054 ,  G02B6/04 ,  G02B6/241 ,  G02B6/3624 ,  G02B6/3887 ,  G02B6/40

    摘要： The variable stiffness electrically conductive catheter shaft includes one or more electrically conductive members, and at least one coaxial layer of heat shrink polymer disposed over the one or more electrically conductive members of a length shorter than the one or more electrically conductive members, to provide variations in stiffness along the length of the shaft. The variable stiffness electrically conductive catheter shaft preferably includes a plurality of coaxial layers of heat shrink polymer encapsulating the one or more electrically conductive members, extending from the proximal end of the one or more electrically conductive members toward the distal end, the plurality of coaxial layers having different lengths to provide the electrically conductive catheter shaft with varying stiffness over the length of the electrically conductive catheter shaft.

    摘要翻译： 可变刚度导电导管轴包括一个或多个导电构件，以及设置在比一个或多个导电构件短的长度的一个或多个导电构件上方的至少一个热收缩聚合物同轴层，以提供变化 沿着轴的长度的刚度。 可变刚度导电导管轴优选地包括多个同轴层的热收缩聚合物，其包封一个或多个导电构件，从一个或多个导电构件的近端向远端延伸，多个同轴层 具有不同的长度以在导电导管轴的长度上提供具有变化的刚度的导电导管轴。

    Micro-strand cable with enhanced radiopacity
    68.
    发明授权
    Micro-strand cable with enhanced radiopacity 有权
    具有增强射线不透性的微绞线

    公开(公告)号：US06475169B2

    公开(公告)日：2002-11-05

    申请号：US09754391

    申请日：2001-01-02

    申请人： David A. Ferrera

    发明人： David A. Ferrera

    IPC分类号： A61B500

    CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/1219 ,  A61B90/39 ,  A61B2017/00867 ,  A61B2017/12072 ,  A61M2025/09191

    摘要： This invention relates generally to emplacable devices for interventional therapeutic treatment or vascular surgery, and more particularly concerns a stranded micro-cable with enhanced radiopacity that can be used to fabricate a vascular device, a stent, a guidewire or the like. The micro-cable is made of strands of a material exhibiting super-elasticity or shape memory properties, such as nickel-titanium, and includes a strand of radiopaque material, such as platinum or gold, in order to provide a radiopaque marker during interventional therapeutic treatment or vascular surgery. The micro-cable can be used to form occluding coils which can be used in devices to restrict, reinforce, or to occlude areas of small diameter vasculature such as an aneurysm or malformation in an artery or vein in the brain.

    摘要翻译： 本发明一般涉及用于介入治疗或血管手术的可用装置，更具体地涉及可用于制造血管装置，支架，导丝等的具有增强的射线不透性的绞合微电缆。 微电缆由具有超弹性或形状记忆性质的材料的线制成，例如镍钛，并且包括一排不透射线材料，例如铂或金，以便在介入治疗期间提供不透射线的标记 治疗或血管手术。 微电缆可用于形成闭塞线圈，其可用于限制，加强或阻塞小直径脉管系统的区域，例如动脉瘤或脑中的动脉或静脉中的畸形。

    Clot retrieval device
    69.
    发明授权
    Clot retrieval device 有权
    凝块检索装置

    公开(公告)号：US06350271B1

    公开(公告)日：2002-02-26

    申请号：US09312931

    申请日：1999-05-17

    申请人： Daniel R. Kurz ,  David A. Ferrera

    发明人： Daniel R. Kurz ,  David A. Ferrera

    IPC分类号： A61B1722

    CPC分类号： A61B17/22031 ,  A61B17/221 ,  A61B2017/00867 ,  A61B2017/00871 ,  A61B2017/22034 ,  A61B2017/2217

    摘要： The shape memory clot retrieval device can be placed in the vasculature of a patient for retrieving and removing distal clots. The clot retrieval device has an elongated catheter member that can be inserted in the vasculature, with one or more clot retrieval members on the elongated catheter member that are movable between an initial compressed configuration in which the clot retrieval device is inserted into the vasculature and an expanded configuration extending outwardly from the elongated catheter member to trap and hold clots within the vessel. The clot retrieval device typically can be introduced to the desired treatment site in the vasculature through a guiding catheter.

    摘要翻译： 形状记忆凝块取出装置可以放置在患者的脉管系统中，用于检索和去除远端血块。 凝块取出装置具有细长的导管构件，该导管构件可以插入脉管系统中，细长的导管构件上的一个或多个凝块取回构件可以在其中凝块取出装置插入脉管系统的初始压缩构型和 扩张构型从细长的导管构件向外延伸以将血块捕获并保持在血管内。 凝块回收装置通常可以通过引导导管引入脉管系统中的期望的治疗部位。

    Shape memory polymer intravascular delivery system with heat transfer medium
    70.
    发明授权
    Shape memory polymer intravascular delivery system with heat transfer medium 有权
    形状记忆聚合物血管内传递系统与传热介质

    公开(公告)号：US06224610B1

    公开(公告)日：2001-05-01

    申请号：US09143904

    申请日：1998-08-31

    申请人： David A. Ferrera

    发明人： David A. Ferrera

    IPC分类号： A61F1100

    CPC分类号： A61F2/95 ,  A61B2017/12077 ,  A61B2018/00005

    摘要： The intravascular delivery system includes an elongated, flexible heat pipe pusher member, a therapeutic device to be placed within the vasculature of a patient, and a shape memory collar detachably mounting the therapeutic device for placement of the therapeutic device within the vasculature. The shape memory collar is disposed either the therapeutic device or the flexible heat pipe pusher member and connects the therapeutic device and the heat pipe pusher member. In a presently preferred embodiment, the shape memory collar is made of nickel titanium alloy.

    摘要翻译： 血管内递送系统包括细长的，柔性的热管推动器构件，放置在患者的脉管系统内的治疗装置和可拆卸地安装治疗装置的形状记忆套管，用于将治疗装置放置在脉管系统内。 形状记忆轴环设置有治疗装置或柔性热管推动器构件，并且连接治疗装置和热管推动器构件。 在目前优选的实施例中，形状记忆环由镍钛合金制成。