摘要:
Light-activated antimicrobial devices and articles are disclosed. The devices include a light source and a light-activated antimicrobial article comprising a photosensitizer and a viscoelastic material such as a pressure sensitive adhesive adapted to receive light from the light source. The viscoelastic material may be adapted to transport light by total internal reflection. The photosensitizer may comprise a dye, a metal oxide or a composition that comprises anions that oxidize or react to form a gas. Upon activation of the light source, the photosensitizer absorbs light from the light source such that antimicrobial activity is exhibited. The photosensitizer may be included in the light-activated antimicrobial article or it may be provided as a topical composition that is separate from the article. The light-activated antimicrobial articles and devices may have constructions similar to those of wound dressings.
摘要:
Skin antiseptic composition dispensers and methods of use are disclosed. The skin antiseptic composition dispenser may include a container with one or more walls that are substantially impermeable to ethylene oxide gas during normal ethylene oxide sterilization processes. In some embodiments, the container may include flexible walls free of metallic foil barrier layers. The containers may also include one or more vents in addition to one or more openings used to dispense the skin antiseptic composition within the container. The dispenser may include an applicator with a hydrophilic foam.
摘要:
Water-in-oil emulsions, compositions, and methods that include a vinyl polymer that includes ethylene oxide-containing side chains and alkyl-Y-containing side chains, wherein Y is O or NR, wherein R is H or CH3, and wherein the alkyl group of the alkyl-Y-containing side chain has at least 4 carbon atoms on average in a cyclic, branched-, or straight-chain configuration and optionally including one or more heteroatoms.
摘要:
The present invention discloses a nasal dilator comprising at least one breathable layer of adhesive-coated high MVTR layer, such as a polyurethane film, one or more adhesive-coated high modulus “spring” elements for dilating the nasal passages by applying a tension force to the skin, and a carrier delivery system. The carrier delivery system comprises a separation line or split through the carrier to allow for easy delivery of the nasal dilator. The carrier aids in the handling and delivery of the thin adhesive-coated high MVTR layer.
摘要:
Pharmaceutical formulations comprising an immune response modifier (IRM) chosen from imidazoquinoline amines, imidazotetrahydroquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, 1,2-bridged imidazoquinoline amines, thiazolo-quinolineamines, oxazolo-quinolinamines, thiazolo-pyridinamines, oxazolo-pyridinamines, imidazonaphthyridine amines, tetrahydroimidazonaphthyridine amines, and thiazolonaphthyridine amines; a fatty acid; and a hydrophobic, aprotic component miscible with the fatty acid are useful for the treatment of dermal associated conditions. Novel topical formulations are provided. In one embodiment, the topical formulations are advantageous for treatment of actinic keratosis, postsurgical scars, basal cell carcinoma, atopic dermatitis, and warts.
摘要:
Polypropylene fibers and devices that include a fatty acid monoglyceride added to the polypropylene as a melt additive are described. A hydrophilic enhancer material can be advantageously added to the polypropylene as a melt additive to enhance the hydrophilicity of the fibers and devices. An antimicrobial enhancer material can be added to the fibers to enhance the antimicrobial activity.
摘要:
A hydroalcoholic lotion is disclosed which comprises (a) a lower alcohol and water in a weight ratio of about 35:65 to 100:0, and (b) between at least 0.5% and 8% by weight thickener system comprised of at least one emulsifier present in at least 0.05% by weight wherein the composition in a polymer free state has a viscosity of at least 4,000 centipoise at 23 degrees C. and wherein the emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The hydroalcoholic composition is useful as a hand preparation such as a lotion or as a presurgical scrub replacement.
摘要:
An aqueous adhesive composition includes a polymer adhesive material having a pH of less than 7, a cationic thickener or an anionic thickener formed from at least one anionic monomer having a pKa of less than 3, and water. The adhesive composition has a stringing length of 9 cm or less and a sag distance of 10 mm or less.
摘要:
Polymeric beads and methods of making the polymeric beads are described. The polymeric beads are crosslinked hydrogels or dried hydrogels. The polymeric beads are formed from droplets of a precursor composition that are exposed to radiation. The droplets are totally surrounded by a gas phase. The precursor composition contains a polar solvent and a polymerizable material miscible in the polar solvent. The polymerizable material has an average number of ethylenically unsaturated groups per monomer molecule equal to at least 1.2.