-
61.发明授权Method and apparatus for forming a feature in a workpiece by laser ablation with a laser beam having an adjustable intensity profile to redistribute the energy density impinging on the workpiece 失效通过具有可调强度分布的激光束通过激光烧蚀在工件中形成特征的方法和装置，以重新分布冲击在工件上的能量密度公开(公告)号：US08158904B2
公开(公告)日：2012-04-17
申请号：US10918841
申请日：2004-08-13
申请人： Jan Weber , Thomas J. Holman
发明人： Jan Weber , Thomas J. Holman
CPC分类号： B23K26/066 , B23K26/073 , B23K26/384 , B23K26/389
摘要： A method and apparatus is provided for removing material from an outer surface of a workpiece such as a catheter or other medical device. The method begins by generating a laser beam having an intensity profile and directing the laser beam onto the outer surface of the workpiece. After the laser beam is generated, its intensity profile is adjusted by a component such as a diffractive optical element (DOE) or a holographic optical element (HOE) so that material can be removed from the workpiece by ablation in a prescribed manner.
摘要翻译： 提供了用于从诸如导管或其它医疗装置的工件的外表面去除材料的方法和装置。 该方法通过产生具有强度分布并将激光束引导到工件的外表面上的激光束开始。 在产生激光束之后，其强度分布由诸如衍射光学元件（DOE）或全息光学元件（HOE）的部件调节，使得可以通过以规定的方式通过烧蚀从材料中去除材料。
-
62.发明授权公开(公告)号：US08152759B2
公开(公告)日：2012-04-10
申请号：US12077603
申请日：2008-03-20
申请人： Liliana Atanasoska , Thomas J. Holman , Jan Weber , Robert Warner , Scott Schewe
发明人： Liliana Atanasoska , Thomas J. Holman , Jan Weber , Robert Warner , Scott Schewe
IPC分类号： A61M29/00
摘要： The invention generally relates to internal (e.g., implantable, insertable, etc.) drug delivery devices which contain the following: (a) one or more sources of one or more therapeutic agents; (b) one or more first electrodes, (c) one or more second electrodes and (d) one or more power sources for applying voltages across the first and second electrodes. The power sources may be adapted, for example, to promote electrically assisted therapeutic agent delivery within a subject, including electroporation and/or iontophoresis. In one aspect of the invention, the first and second electrodes are adapted to have tissue of a subject positioned between them upon deployment of the medical device within the subject, such that an electric field may be generated, which is directed into the tissue. Furthermore, the therapeutic agent sources are adapted to introduce the therapeutic agents into the electric field. In another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of ion-conductive polymers and one or more types of charged therapeutic agents. In yet another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of electrically conductive polymers and one or more types of charged therapeutic agents.
摘要翻译： 本发明一般涉及含有以下物质的内部（例如，可植入，可插入等）药物递送装置：（a）一种或多种一种或多种治疗剂来源; （b）一个或多个第一电极，（c）一个或多个第二电极和（d）用于在第一和第二电极上施加电压的一个或多个电源。 电源可以适应于例如促进受试者内的电辅助治疗剂递送，包括电穿孔和/或离子电渗疗法。 在本发明的一个方面中，第一和第二电极适于在医疗装置在受试者内展开时使被检体的组织位于它们之间，使得可以产生被引导到组织中的电场。 此外，治疗剂源适于将治疗剂引入电场。 另一方面，治疗剂来源是含有一种或多种类型的离子导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。 在另一方面，治疗剂来源是含有一种或多种类型的导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。
-
63.发明授权Medical devices formed with a sacrificial structure and processes of forming the same 有权用牺牲结构形成的医疗器械及其形成方法公开(公告)号：US08070718B2
公开(公告)日：2011-12-06
申请号：US11010810
申请日：2004-12-13
申请人： Jan Weber , Scott Schewe , Thomas J. Holman
发明人： Jan Weber , Scott Schewe , Thomas J. Holman
CPC分类号： A61M25/1029 , A61M25/0009 , A61M25/0045 , A61M25/1036 , A61M25/104 , A61M2025/1075 , A61M2025/1086
摘要： Medical devices formed using a sacrificial structure, and processes of forming the devices therefrom.
摘要翻译： 使用牺牲结构形成的医疗器械，以及由其形成器件的工艺。
-
公开(公告)号：US08029554B2
公开(公告)日：2011-10-04
申请号：US11934362
申请日：2007-11-02
CPC分类号： A61L31/12 , A61L31/022 , A61L31/088 , Y10T428/12104 , Y10T428/12486 , Y10T428/12993
摘要： An endoprosthesis such as a stent is composed of a metal or ceramic, such as Irox, embedded in the stent material.
摘要翻译： 诸如支架的内假体由嵌入在支架材料中的金属或陶瓷（例如Irox）组成。
-
65.发明授权Method and apparatus for high reliability data storage and retrieval operations in multi-level flash cells 失效用于多级闪存单元中高可靠性数据存储和检索操作的方法和装置公开(公告)号：US07941592B2
公开(公告)日：2011-05-10
申请号：US12228795
申请日：2008-08-14
IPC分类号： G06F12/00
CPC分类号： G11C11/5628 , G11C2211/5641
摘要： One or more multi-level NAND flash cells are operated so as to store only single-level data, and these operations achieve an increased level of charge separation between the data states of the single-level operation by requiring a write to both the upper and lower pages, even though only one bit of data is being stored. That is, the second write operation increases the difference in floating gate charge between the erased state and the programmed state of the first write operation without changing the data in the flash memory cell. In one embodiment, a controller instructs the flash memory to perform two write operations for storing a single bit of data in an MLC flash cell. In another embodiment, the flash memory recognizes that a single write operation is directed a high reliability memory area and internally generates the required plurality of programming steps to place at least a predetermined amount of charge on the specified floating gate.
摘要翻译： 操作一个或多个多电平NAND闪存单元以仅存储单级数据，并且这些操作通过要求写入上层和第二级的单级操作来实现单级操作的数据状态之间的电荷分离水平的提高 即使只有一位数据被存储，也是较低的页面。 也就是说，第二写入操作增加擦除状态和第一写操作的编程状态之间的浮栅电荷的差异，而不改变闪存单元中的数据。 在一个实施例中，控制器指示闪速存储器执行用于在MLC闪存单元中存储单个数据位的两个写入操作。 在另一个实施例中，闪速存储器识别出单个写入操作被引导到高可靠性存储区域，并且在内部产生所需的多个编程步骤以将至少预定量的电荷放置在指定的浮动栅极上。
-
公开(公告)号：US20110071559A1
公开(公告)日：2011-03-24
申请号：US12955578
申请日：2010-11-29
申请人： Thomas J. Holman , Jan Weber
发明人： Thomas J. Holman , Jan Weber
CPC分类号： A61B17/320725 , A61B2017/22061 , A61M25/1002 , A61M25/1011 , A61M2025/0058 , A61M2025/1045 , A61M2025/1081 , A61M2025/1086
摘要： A catheter assembly for deployment in a vessel includes a catheter shaft extending from a proximal end portion to a distal end portion. A balloon is operatively coupled to the distal end portion of the catheter shaft. At least one cutting member is coupled to the catheter assembly. As the balloon is inflated, the cutting member is moved to a position to cut a portion of the vessel.
摘要翻译： 用于展开在容器中的导管组件包括从近端部分延伸到远端部分的导管轴。 气囊可操作地联接到导管轴的远端部分。 至少一个切割构件联接到导管组件。 当气囊膨胀时，切割构件移动到切割容器的一部分的位置。
-
67.发明授权公开(公告)号：US07850645B2
公开(公告)日：2010-12-14
申请号：US11055930
申请日：2005-02-11
申请人： Liliana Atanasoska , Thomas J. Holman , Jan Weber , Robert Warner , Scott Schewe
发明人： Liliana Atanasoska , Thomas J. Holman , Jan Weber , Robert Warner , Scott Schewe
IPC分类号： A61M29/00
摘要： The invention generally relates to internal (e.g., implantable, insertable, etc.) drug delivery devices which contain the following: (a) one or more sources of one or more therapeutic agents; (b) one or more first electrodes, (c) one or more second electrodes and (d) one or more power sources for applying voltages across the first and second electrodes. The power sources may be adapted, for example, to promote electrically assisted therapeutic agent delivery within a subject, including electroporation and/or iontophoresis. In one aspect of the invention, the first and second electrodes are adapted to have tissue of a subject positioned between them upon deployment of the medical device within the subject, such that an electric field may be generated, which is directed into the tissue. Furthermore, the therapeutic agent sources are adapted to introduce the therapeutic agents into the electric field. In another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of ion-conductive polymers and one or more types of charged therapeutic agents. In yet another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of electrically conductive polymers and one or more types of charged therapeutic agents.
摘要翻译： 本发明一般涉及含有以下物质的内部（例如，可植入，可插入等）药物递送装置：（a）一种或多种一种或多种治疗剂来源; （b）一个或多个第一电极，（c）一个或多个第二电极和（d）用于在第一和第二电极上施加电压的一个或多个电源。 电源可以适应于例如促进受试者内的电辅助治疗剂递送，包括电穿孔和/或离子电渗疗法。 在本发明的一个方面中，第一和第二电极适于在医疗装置在受试者内展开时使被检体的组织位于它们之间，使得可以产生被引导到组织中的电场。 此外，治疗剂源适于将治疗剂引入电场。 另一方面，治疗剂来源是含有一种或多种类型的离子导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。 在另一方面，治疗剂来源是含有一种或多种类型的导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。
-
公开(公告)号：US07799068B2
公开(公告)日：2010-09-21
申请号：US11493306
申请日：2006-07-26
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61B17/12045 , A61B17/12118 , A61B2017/00004 , A61B2017/00535 , A61B2017/1205 , A61B2017/12127 , A61F2/89 , A61F2/94 , A61F2/95 , A61F2/954 , A61F2002/065 , A61F2002/072 , A61F2002/075 , A61F2250/0003
摘要： Percutaneous treatment of aortic aneurysms and like vascular anomalies by an apparatus and method wherein the apparatus is delivered via catheter and comprises a sleeve with at least one peripheral conduit which is caused to assume an expanded, rigid configuration by the introduction of a chemical or mechanical hardening means, whereby the sleeve is caused to assume an open cylindrical configuration for fluid flow therethrough.
摘要翻译： 通过一种装置和方法经皮治疗主动脉瘤和类似的血管异常，其中该装置通过导管输送并且包括具有至少一个周边导管的套筒，其通过引入化学或机械硬化而被引入膨胀的刚性构型 意味着使套筒呈现开口的圆柱形结构，用于流过其中的流体。
-
公开(公告)号：US20100131004A1
公开(公告)日：2010-05-27
申请号：US12695941
申请日：2010-01-28
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61F2/24 , A61F2/2493 , A61F2/86 , A61F2002/018 , A61F2002/068 , A61F2230/0006 , A61F2230/0067
摘要： Improved methods and apparatus for capturing emboli and subsequently removing or immobilizing the captured emboli are described. Emboli can be captured within a blood vessel and can be withdrawn to a position exterior to the blood vessel. Some filters can remain within a blood vessel yet direct emboli to a position exterior to the blood vessel.
摘要翻译： 描述了用于捕获栓塞以及随后去除或固定所捕获的栓塞的改进的方法和装置。 栓塞可以在血管内捕获并且可以撤回到血管外部的位置。 一些过滤器可以保留在血管内，但是直接栓塞到血管外部的位置。
-
70.发明申请公开(公告)号：US20100069839A1
公开(公告)日：2010-03-18
申请号：US12620368
申请日：2009-11-17
申请人： Thomas J. Holman , Louis G. Ellis , Gregory K. Olson , Linda R. Lorentzen-Cornelius , Richard J. Traxler , Scott M. Hanson , Tracee E.J. Eidenschink , Sonja J.K. Williams
发明人： Thomas J. Holman , Louis G. Ellis , Gregory K. Olson , Linda R. Lorentzen-Cornelius , Richard J. Traxler , Scott M. Hanson , Tracee E.J. Eidenschink , Sonja J.K. Williams
IPC分类号： A61M31/00
CPC分类号： A61M25/104 , A61F2/0095 , A61F2/958 , A61F2002/9583 , A61M2025/1081
摘要： A balloon catheter is provided having an expandable distal portion and balloon protector means comprising a first removable sleeve having a variable inner diameter to ease sliding the first sleeve over the balloon, and an optional second removable (outer) sleeve positioned over the inner sleeve, the second (outer) sleeve having a constrictive relationship with the first (inner) sleeve, said first and second sleeves being removed prior to use of the catheter. A stent delivery system is provided to facilitate introduction and placement of a stent, and includes a catheter having an expandable distal portion constructed and arranged for expanding the outer diameter of the catheter from a contracted state to an expanded state, said distal portion further comprising a balloon and at least one dam over which the balloon extends, and a stent positioned around the distal portion of the catheter around the balloon or gripper linear control device, said stent having a contracted condition, being sized in the contracted condition to closely surround the balloon in the contracted state, and being expandable to an expanded condition; a first removable (inner) sleeve in the region of the distal portion of the catheter positioned around the stent (and between the dams where the device comprises two dams), said first sleeve comprising a first end, a second end and a variable inner diameter to ease sliding the sleeve over the balloon and stent; an optional second removable (outer) sleeve positioned over the stent, first sleeve and at least one dam, said second (outer) sleeve having a constrictive relationship with the first (inner) sleeve, whereby when compressed by the outer sleeve, the inner sleeve will have an inner diameter approximately equal to or less than the outer profile of the collapsed balloon over the at least one dam, said first and second sleeves being removed prior to use of the stent delivery system and release of the stent by expansion of the balloon.
-
-
-
-
-
-
-
-
-
搜索结果
116 条记录 (耗时 0.051 秒)
