公开(公告)号：US20070288062A1

公开(公告)日：2007-12-13

申请号：US11733332

申请日：2007-04-10

申请人： Jeffrey Stahmann ,  Andrew Kramer

发明人： Jeffrey Stahmann ,  Andrew Kramer

IPC分类号： A61N1/365

CPC分类号： A61N1/3622 ,  A61N1/3621 ,  A61N1/3624 ,  A61N1/3627 ,  A61N1/3684 ,  A61N1/3688 ,  A61N1/395 ,  A61N1/3962

摘要： A method for operating a cardiac pacemaker in which the mode of operation of the pacemaker is altered in response to detecting an episode of atrial tachycardia. In accordance with the invention, the pacemaker's pacing mode is altered in a manner that attempts to maintain hemodynamic stability during the atrial tachycardia. Such a mode switch is particularly applicable to pacemaker patients suffering from some degree of congestive heart failure.

摘要翻译： 一种用于操作心脏起搏器的方法，其中起搏器的操作模式响应于检测心房心动过速的发作而改变。 根据本发明，起搏器的起搏模式以在心房心动过速期间维持血液动力学稳定性的方式改变。 这种模式切换特别适用于患有某种程度充血性心力衰竭的起搏器患者。

公开(公告)号：US20070150014A1

公开(公告)日：2007-06-28

申请号：US11315032

申请日：2005-12-22

申请人： Andrew Kramer ,  Joseph Pastore ,  Jeffrey Stahmann ,  Rodney Salo ,  Jesse Hartley

发明人： Andrew Kramer ,  Joseph Pastore ,  Jeffrey Stahmann ,  Rodney Salo ,  Jesse Hartley

IPC分类号： A61N1/365

CPC分类号： A61N1/36557 ,  A61B5/6816 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/6838 ,  A61N1/36114 ,  A61N1/36564

摘要： A cardiac rhythm management (CRM) system includes a non-invasive hemodynamic sensing device and an implantable medical device to sense a hemodynamic signal and derive one or more cardiac performance parameters from the hemodynamic signal. The non-invasive hemodynamic sensing device includes at least a portion configured for external attachment to a body in which the implantable medical device is implanted. The one or more cardiac performance parameters are used for various diagnostic, monitoring, and therapy control purposes.

摘要翻译： 心律管理（CRM）系统包括非侵入性血液动力学感测装置和可植入医疗装置，用于感测血液动力学信号并从血流动力学信号导出一个或多个心脏性能参数。 非侵入式血流动力学检测装置包括至少一部分，其构造成用于外部附接到其中植入可植入医疗装置的主体。 一个或多个心脏性能参数用于各种诊断，监测和治疗控制目的。

公开(公告)号：US20070142864A1

公开(公告)日：2007-06-21

申请号：US11558083

申请日：2006-11-09

申请人： Imad Libbus ,  Andrew Kramer

发明人： Imad Libbus ,  Andrew Kramer

IPC分类号： A61N1/18

CPC分类号： A61N1/36139 ,  A61N1/3601 ,  A61N1/3611 ,  A61N1/36114 ,  A61N1/36117 ,  A61N1/36135 ,  A61N1/3627 ,  A61N1/36535 ,  A61N1/36542 ,  A61N1/3655 ,  A61N1/36564 ,  A61N1/36571 ,  A61N1/37288

摘要： According to an embodiment of a method for providing neural stimulation, activity is sensed, and neural stimulation is automatically controlled based on the sensed activity. An embodiment determines periods of rest and periods of exercise using the sensed activity, and applies neural stimulation during rest and withdrawing neural stimulation during exercise. Other embodiments are provided herein.

摘要翻译： 根据用于提供神经刺激的方法的实施例，感测活动，并且基于感测的活动自动控制神经刺激。 实施例使用感测到的活动来确定休息时间和运动周期，并且在休息期间应用神经刺激并且在运动期间撤回神经刺激。 本文提供了其他实施例。

公开(公告)号：US20070118179A1

公开(公告)日：2007-05-24

申请号：US11654942

申请日：2007-01-18

申请人： Andrew Kramer ,  Albert Maarse ,  Jeffrey Stahmann ,  Rene Wentkowski

发明人： Andrew Kramer ,  Albert Maarse ,  Jeffrey Stahmann ,  Rene Wentkowski

IPC分类号： A61N1/362

CPC分类号： A61N1/3627 ,  A61N1/3622 ,  A61N1/368

摘要： A device and method for multi chamber pacing a patient's heart having heart failure and intrinsic conduction, wherein ventricular tracking is used to pace the ventricle when the sinus rate exceeds a preset atrial maximum tracking rate. The ventricular tracking pacemaker increases the range of pacing the ventricle. The ventricular tracking minimizes the loss of ventricular pacing caused by intrinsic conduction when the sinus rate is below an atrial maximum tracking rate, and it induces a new ventricular pacing behavior for sinus rates above the atrial maximum tracking rate without any significant pacing hysteresis as the sinus rate returns towards the lower rate limit.

摘要翻译： 一种用于多室起搏具有心力衰竭和内在传导的患者心脏的装置和方法，其中当窦速率超过预设的心房最大跟踪率时，使用心室跟踪来调节心室。 心室跟踪起搏器增加心室起搏的范围。 当窦速度低于心房最大跟踪率时，心室跟踪最小化由内在传导引起的心室起搏损失，并且其诱导窦速率高于心房最大跟踪率的新的心室起搏行为，而没有任何明显的起搏滞后作为窦 利率回到较低的汇率限制。

公开(公告)号：US20070055317A1

公开(公告)日：2007-03-08

申请号：US11220023

申请日：2005-09-06

申请人： Jeffrey Stahmann ,  Joseph Pastore ,  Andrew Kramer ,  Rodney Salo ,  Jesse Hartley

发明人： Jeffrey Stahmann ,  Joseph Pastore ,  Andrew Kramer ,  Rodney Salo ,  Jesse Hartley

IPC分类号： A61N1/365

CPC分类号： A61N1/3627 ,  A61N1/36114 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/36564 ,  A61N1/3684

摘要： A method and device for delivering pre-excitation pacing to prevent or reduce cardiac remodeling following a myocardial infarction is described. The pre-excitation pacing is modulated in accordance with an intravascular pressure measurement in order to balance the beneficial effects of stress reduction with hemodynamic compromise.

摘要翻译： 描述了用于递送预激发起搏以预防或减少心肌梗塞后的心脏重塑的方法和装置。 根据血管内压力测量调节预激发起搏，以平衡应力减少与血液动力学妥协的有益效果。

公开(公告)号：US20070043396A1

公开(公告)日：2007-02-22

申请号：US11589608

申请日：2006-10-30

申请人： Jeffrey Stahmann ,  Rene Wentkowski ,  Andrew Kramer ,  James Kalgren

发明人： Jeffrey Stahmann ,  Rene Wentkowski ,  Andrew Kramer ,  James Kalgren

IPC分类号： A61N1/362

CPC分类号： A61N1/36507 ,  A61N1/3627 ,  A61N1/3684

摘要： A system and method recording sensing and pacing events in a cardiac rhythm management device. The method may be particularly useful in assessment of pacing parameters for ventricular resynchronization therapy.

摘要翻译： 在心律管理装置中记录感测和起搏事件的系统和方法。 该方法在评价心室再同步治疗的起搏参数方面特别有用。

公开(公告)号：US20060287683A1

公开(公告)日：2006-12-21

申请号：US11276741

申请日：2006-03-13

申请人： Joseph Pastore ,  Rodney Salo ,  Jesse Hartley ,  Andrew Kramer ,  Jeffrey Stahmann

发明人： Joseph Pastore ,  Rodney Salo ,  Jesse Hartley ,  Andrew Kramer ,  Jeffrey Stahmann

IPC分类号： A61N1/362

CPC分类号： A61N1/3627 ,  A61N1/36521 ,  A61N1/3684

摘要： A method and device for delivering pre-excitation pacing to prevent or reduce cardiac remodeling following a myocardial infarction is described. The pre-excitation pacing is modulated in accordance with an assessment of cardiac function in order to balance the beneficial effects of stress reduction with hemodynamic compromise.

摘要翻译： 描述了用于递送预激发起搏以预防或减少心肌梗塞后的心脏重塑的方法和装置。 根据心脏功能的评估调节预激励起搏，以平衡应力减少与血液动力学妥协的有益效果。

公开(公告)号：US20060271118A1

公开(公告)日：2006-11-30

申请号：US11137038

申请日：2005-05-25

申请人： Imad Libbus ,  Andrew Kramer ,  William Linder ,  Jeffrey Stahmann

发明人： Imad Libbus ,  Andrew Kramer ,  William Linder ,  Jeffrey Stahmann

IPC分类号： A61N1/36

CPC分类号： A61N1/36128 ,  A61M5/1723 ,  A61N1/3605 ,  A61N1/36053 ,  A61N1/36114 ,  A61N1/36135 ,  A61N1/3688

摘要： Various aspects of the present subject matter relate to an implantable device. Various device embodiments comprise at least one port to connect to at least one lead with at least electrode, stimulation circuitry connected to the at least one port and adapted to provide at least one neural stimulation therapy to at least one neural stimulation target using the at least one electrode, sensing circuitry connected to the at least one port and adapted to provide a sensed signal, and a controller connected to the stimulation circuitry to provide the at least one neural stimulation therapy and to the sensing circuitry to receive the sensed signal. In response to a triggering event, the controller is adapted to switch between at least two modes. Other aspects and embodiments are provided herein.

公开(公告)号：US20060253157A1

公开(公告)日：2006-11-09

申请号：US11122968

申请日：2005-05-05

申请人： Imad Libbus ,  Andrew Kramer ,  William Linder ,  Jeffrey Stahmann

发明人： Imad Libbus ,  Andrew Kramer ,  William Linder ,  Jeffrey Stahmann

IPC分类号： A61N1/362

CPC分类号： A61N1/3622 ,  A61N1/36114 ,  A61N1/3962

摘要： A method and apparatus for delivering therapy to treat ventricular tachyarrhythmias is described. In one embodiment, neural stimulation, anti-tachycardia pacing, and shock therapy are employed in a progressive sequence upon detection of a ventricular tachycardia.

公开(公告)号：US20060241725A1

公开(公告)日：2006-10-26

申请号：US11114246

申请日：2005-04-25

申请人： Imad Libbus ,  Andrew Kramer ,  William Linder ,  Jeffrey Stahmann

发明人： Imad Libbus ,  Andrew Kramer ,  William Linder ,  Jeffrey Stahmann

IPC分类号： A61N1/08

CPC分类号： A61N1/365 ,  A61B5/0006 ,  A61B5/044 ,  A61B5/4035 ,  A61B5/4041 ,  A61B5/4047 ,  A61B5/742 ,  A61N1/36114 ,  A61N1/37247

摘要： A presentation device such as a display screen or a printer provides for simultaneous presentation of temporally aligned cardiac and neural signals. At least one cardiac signal in the form of a cardiac signal trace or cardiac event markers and at least one neural signal in the form of a neural signal trace or neural event markers are simultaneously presented. The cardiac signal indicates sensed cardiac electrical activities and/or cardiac stimulation pulse deliveries. The neural signal indicates sensed neural electrical activities and/or neural stimulation pulse deliveries. In one embodiment, the presentation device is part of an external system communicating with an implantable system that senses cardiac and/or neural signals and delivers cardiac and/or neural stimulation pulses.

摘要翻译： 诸如显示屏或打印机的呈现装置提供用于同时呈现时间上对准的心脏和神经信号。 同时呈现心脏信号迹线或心脏事件标记形式的至少一个心脏信号和神经信号轨迹或神经事件标记形式的至少一个神经信号。 心脏信号表示感测到的心脏电活动和/或心脏刺激脉冲输送。 神经信号表示感测的神经电活动和/或神经刺激脉冲输送。 在一个实施例中，呈现装置是与感测心脏和/或神经信号并传递心脏和/或神经刺激脉冲的可植入系统通信的外部系统的一部分。