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92 条记录 (耗时 0.038 秒)

    Surgical saw blade device and system
    61.
    发明授权
    Surgical saw blade device and system 有权
    手术锯片装置及系统

    公开(公告)号：US08672943B2

    公开(公告)日：2014-03-18

    申请号：US12464825

    申请日：2009-05-12

    申请人： Michael Fisher ,  Barjinder Chana

    发明人： Michael Fisher ,  Barjinder Chana

    IPC分类号： A61B17/00

    CPC分类号： A61B17/142

    摘要： A saw blade assembly for use with a driver having an oscillatory drive member comprises an elongate sheath and an elongate monolithic blade. The sheath's proximal end is removably mountable on the driver. The sheath has an open interior which receives the blade. The blade's proximal end is pivotably mounted to the sheath's proximal end. The blade's distal cutting end extends out of the sheath's distal end and is transverse to the blade's central longitudinal axis. When cutting bone, the drive member pivots the blade's cutting end back and forth in an arc about a pivot point at the blade's proximal end while the driver holds the sheath stationary to protect surrounding tissues from the motions of the remainder of the blade. The long pivot radius between the proximal pivot point and the distal cutting end contributes to minimizing the angle of engagement of the cutting end to the bone.

    摘要翻译： 与具有振荡驱动构件的驱动器一起使用的锯片组件包括细长护套和细长整体刀片。 护套的近端可拆卸地安装在驱动器上。 护套具有接收刀片的敞开内部。 刀片的近端可枢转地安装到护套的近端。 刀片的远端切割端延伸出护套的远端，横向于刀片的中心纵向轴线。 当切割骨骼时，驱动构件使刀片的切割端部围绕刀片近端的枢转点以弧形方式来回旋转，同时驾驶员将护套固定以保护周围组织免受叶片的其余部分的运动。 近端枢转点和远端切割端之间的长的枢转半径有助于最小化切割端与骨骼的接合角度。

    CONTINUOUS PERFUSION BIOREACTOR SYSTEM
    67.
    发明申请
    CONTINUOUS PERFUSION BIOREACTOR SYSTEM 有权
    连续曝光生物反应器系统

    公开(公告)号：US20090035856A1

    公开(公告)日：2009-02-05

    申请号：US12124039

    申请日：2008-05-20

    申请人： Parrish M. Galliher ,  Geoffrey L. Hodge ,  Michael Fisher ,  Patrick Guertin ,  Dan Mardirosian

    发明人： Parrish M. Galliher ,  Geoffrey L. Hodge ,  Michael Fisher ,  Patrick Guertin ,  Dan Mardirosian

    IPC分类号： C12N5/06 ,  C12M1/00

    CPC分类号： C12M29/10 ,  B01D29/13 ,  C12M23/14 ,  C12M23/26 ,  C12M23/48 ,  C12M27/02 ,  C12M27/20 ,  C12M29/00 ,  C12M29/18 ,  C12M47/10

    摘要： Systems and methods for containing and manipulating liquids, including vessels and unit operations or components of cell culture, cell containment, bioreactor, and/or pharmaceutical manufacturing systems, are provided. In certain embodiments, such vessels and unit operations are directed to continuous perfusion reactor or bioreactor systems and may include one or more disposable components. For instance, in one aspect, a system includes an apparatus in the form of a bioreactor for harvesting cells which produce one or more products. The apparatus may include a disposable, collapsible bag adapted for containing a liquid, the collapsible bag in fluid communication with a liquid-solids (e.g., cell) separation device. For example, an outlet of the collapsible bag may be connected to an inlet of the separation device, and an outlet of the separation device may be connected to an inlet of the collapsible bag for recycle. Accordingly, after separating the cells from the liquid in the separation device, the cells can be flowed back into the collapsible bag where they can be re-harvested. Meanwhile, product contained in the liquid can be collected in a separate container. The efficiency of product formation in such a system may be enhanced by using mixing systems described herein.

    摘要翻译： 提供了用于容纳和操纵液体的系统和方法，包括容器和单元操作或细胞培养物，细胞容纳物，生物反应器和/或药物制造系统的组分。 在某些实施方案中，这样的容器和单元操作涉及连续灌注反应器或生物反应器系统，并且可以包括一个或多个一次性组件。 例如，一方面，系统包括生物反应器形式的装置，用于收集产生一种或多种产品的细胞。 该装置可以包括适于容纳液体的一次性可折叠袋，该可折叠袋与液体 - 固体（例如，池）分离装置流体连通。 例如，可折叠袋的出口可以连接到分离装置的入口，并且分离装置的出口可以连接到可折叠袋的入口以用于再循环。 因此，在分离装置中的液体分离细胞后，细胞可以流回到可收缩的袋子中，在那里它们可以被再次收获。 同时，包含在液体中的产品可以收集在单独的容器中。 通过使用本文所述的混合系统可以提高这种系统中产物形成的效率。

    Accoustically Transparent Occlusion Reduction System and Method
    68.
    发明申请
    Accoustically Transparent Occlusion Reduction System and Method 有权
    透声闭塞减少系统及方法

    公开(公告)号：US20080063228A1

    公开(公告)日：2008-03-13

    申请号：US11576175

    申请日：2005-09-30

    申请人： Jorge Mejia ,  Harvey Dillon ,  Michael Fisher

    发明人： Jorge Mejia ,  Harvey Dillon ,  Michael Fisher

    IPC分类号： H04R25/00

    CPC分类号： H04R25/502 ,  H04R25/407 ,  H04R25/505 ,  H04R2460/05

    摘要： A system and method that reduces the perceptual effect resulting from ear occlusion is disclosed. It comprises of an electro-acoustic feedback network that produces phase cancelling sounds in the ear, where a receiver and a microphone are located. A novel control mechanism is disclosed that controls the response of the feedback network to minimise distortion in the ear while maintaining a desired frequency response for external signals. Devices producing the external signal include hearing aids, personal sound devices, in ear monitors, communications headsets and hearing protectors. The integration of the present invention with these devices improves the user's perception of their own voice.

    摘要翻译： 公开了一种降低耳塞闭塞感知效果的系统和方法。 它包括电声反馈网络，其在耳朵中产生相位消除声音，其中接收器和麦克风位于其中。 公开了一种新颖的控制机制，其控制反馈网络的响应以最小化耳朵中的失真，同时保持对外部信号的期望的频率响应。 产生外部信号的装置包括助听器，个人声音装置，耳朵监视器，通信耳机和听力保护器。 本发明与这些装置的集成改善了用户对自己的声音的感知。

    Method and apparatus for achieving rigid attachments for computer components
    69.
    发明申请
    Method and apparatus for achieving rigid attachments for computer components 失效
    用于实现计算机部件的刚性附件的方法和装置

    公开(公告)号：US20070249211A1

    公开(公告)日：2007-10-25

    申请号：US11407020

    申请日：2006-04-19

    申请人： Joseph Corrado ,  Michael Fisher ,  Gerald Monaco ,  Budy Notohardjono

    发明人： Joseph Corrado ,  Michael Fisher ,  Gerald Monaco ,  Budy Notohardjono

    IPC分类号： H01R13/627

    CPC分类号： G06F1/181

    摘要： A method and apparatus used for actuation is provided. In one embodiment, the apparatus comprises an actuation body having a gradually tapered wider end received at one end by an expandable member and at an opposing end by a drive shell. The actuation body being movable from a first position to a second position by means of the drive shell such that this movement causes a looser or tighter fit at the wider end with respect to the expandable member.

    摘要翻译： 提供了用于致动的方法和装置。 在一个实施例中，该装置包括致动体，该致动体具有逐渐变细的较宽端部，其一端通过可扩张构件接收，并且在相对端处由驱动壳体接收。 致动体可借助于驱动壳体从第一位置移动到第二位置，使得该移动使得相对于可扩张构件在较宽端部处更松散或更紧密地配合。

    Transverse acting surgical saw blade
    70.
    发明申请
    Transverse acting surgical saw blade 有权
    横向作用手术锯片

    公开(公告)号：US20070083209A1

    公开(公告)日：2007-04-12

    申请号：US11234754

    申请日：2005-09-23

    申请人： Jon Schenberger ,  Michael Fisher

    发明人： Jon Schenberger ,  Michael Fisher

    IPC分类号： A61B17/00

    CPC分类号： A61B17/142 ,  A61B17/14 ,  A61B2017/00734

    摘要： Various embodiments provide surgical cutting devices and systems for orthopedic and other procedures. Specific embodiments provide saw devices for accessing and cutting subjacent bone and other tissue while minimizing injury to surrounding tissue. One embodiment provides a transverse acting saw blade for performing surgical cuts to bone tissue with minimal injury to surrounding tissue. The blade comprises an elongated member having a first portion and a second portion and a longitudinal and lateral axis. The first portion is configured to engage a drive source to produce longitudinal movement of the first portion that is atraumatic to surrounding tissue. The second portion includes a cutting surface. The longitudinal movement of the first portion is converted to a lateral movement of the second portion that is sufficient to cut engaged bone tissue with the cutting surface. The movement of the second portion is substantially transverse to the movement of the first portion.

    摘要翻译： 各种实施例提供用于矫形和其他手术的外科切割装置和系统。 具体实施例提供用于进入和切割下面的骨骼和其他组织的锯装置，同时使对周围组织的损伤最小化。 一个实施例提供了一种横向作用锯片，用于对周围组织的损伤以最小的损伤进行骨组织的手术切割。 刀片包括具有第一部分和第二部分以及纵向和横向轴线的细长部件。 第一部分被配置为接合驱动源以产生对周围组织无伤害的第一部分的纵向运动。 第二部分包括切割表面。 第一部分的纵向运动被转换为第二部分的横向移动，其足以切割与切割表面接合的骨组织。 第二部分的运动基本上横向于第一部分的运动。