公开(公告)号：US10188500B2

公开(公告)日：2019-01-29

申请号：US15043246

申请日：2016-02-12

申请人： Medtronic Vascular, Inc.

发明人： Keith Perkins ,  Jeffery Argentine ,  Matt Petruska ,  Samuel Robaina ,  Darren Galligan ,  Rajesh Radhakrishnan

IPC分类号： A61F2/06 ,  A61F2/07 ,  A61F2/00

摘要： A scaffolded stent-graft includes a graft material comprising an inner surface and an outer surface. The inner surface defines a lumen within the graft material. The scaffolded stent-graft further includes a scaffold comprising a mesh coupled to the graft material at the outer surface. The scaffold is configured to promote tissue ingrowth therein. In this manner, the scaffold enhances tissue integration into the scaffolded stent-graft. The tissue integration enhances biological fixation of the scaffolded stent-graft in vessels minimizing the possibility of endoleaks and migration.

公开(公告)号：US20170360993A1

公开(公告)日：2017-12-21

申请号：US15621637

申请日：2017-06-13

申请人： Medtronic Vascular, Inc.

发明人： Jeffery Argentine ,  Matt Petruska ,  Keith Perkins ,  Samuel Robaina ,  Darren Galligan ,  Rajesh Radhakrishnan

IPC分类号： A61L27/56 ,  A61L27/52 ,  A61L27/58 ,  A61L27/54

CPC分类号： A61L27/56 ,  A61F2/06 ,  A61F2/07 ,  A61F2002/072 ,  A61F2002/077 ,  A61F2210/0061 ,  A61L27/52 ,  A61L27/54 ,  A61L27/58 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/42

摘要： The present technology relates generally to endovascular prostheses. More particularly, the disclosure relates to endovascular prostheses having an outer surface of a graft material thereof associated with a hydrogel composition, which may swell upon implantation within a blood vessel, thereby mediating various complications associated with endovascular procedures. The hydrogel compositions can also include various stabilizing polymers and active agents to further aid their use in the body.

公开(公告)号：US20170100141A1

公开(公告)日：2017-04-13

申请号：US14877351

申请日：2015-10-07

申请人： Medtronic Vascular, Inc.

发明人： Massimo Morero ,  Giampiero Nicoli ,  Carlo Guala ,  Giovanni Scalvini ,  Marco Miliani ,  Michele Saputo ,  Claudia Vimercati ,  Jeffery Argentine ,  Ludwig Compagnoni ,  Davide Zanetti ,  Claudio Silvestro

IPC分类号： A61B17/22 ,  A61M25/01

CPC分类号： A61B17/22 ,  A61B17/3478 ,  A61B2017/00331 ,  A61B2017/22001 ,  A61B2017/22069 ,  A61B2017/22095 ,  A61M25/0084 ,  A61M25/0194 ,  A61M25/1002 ,  A61M2025/0092 ,  A61M2025/0197 ,  A61M2025/0293

摘要： An occlusion bypassing apparatus for re-entering the true lumen of a vessel after subintimally bypassing an occlusion in a vessel. The apparatus includes an outer shaft component, a needle component, and an inflatable balloon. The outer shaft component has a side port proximal to a distal end thereof and a needle lumen there-through that includes a curved distal portion that terminates at the side port of the outer shaft component. The needle component is configured to be slidably disposed within the needle lumen of the outer shaft component. The inflatable balloon includes a body portion that is disposed distal to the side port of the outer shaft component, and the body portion of the balloon has a flattened profile in an inflated state with first and second chambers that laterally extend from opposing sides of the outer shaft component for stabilizing the apparatus within a subintimal space.

公开(公告)号：US20170027725A1

公开(公告)日：2017-02-02

申请号：US15244157

申请日：2016-08-23

申请人： Medtronic Vascular, Inc.

发明人： Jeffery Argentine

IPC分类号： A61F2/966 ,  A61F2/844

CPC分类号： A61F2/966 ,  A61F2/844 ,  A61F2002/9517

摘要： A delivery system for delivering a prosthesis, the delivery system including a housing, a sheath extending from within the housing, a clutching mechanism housed within the housing, and a cable. The clutching mechanism includes a one-way clutch that transmits a torque from an actuator to an inner shaft assembly when the actuator is rotated in a first direction and does not transmit a torque from the actuator to the inner shaft assembly when the actuator is rotated in a second opposing direction. The actuator is accessible from an exterior of the housing. The cable has a first end coupled to a proximal portion of the sheath and a second end coupled to the inner shaft assembly, and actuation of the actuator causes the actuator to rotate in the first direction, thereby causing the inner shaft assembly to wind up a portion of cable and retract the sheath.

摘要翻译： 用于输送假体的输送系统，所述输送系统包括壳体，从所述壳体内延伸的护套，容纳在所述壳体内的收紧机构和电缆。 离合器包括单向离合器，当致动器在第一方向上旋转时，将致动器的转矩传递到内轴组件，并且当致动器旋转时，该单向离合器不会将致动器的转矩传递到内轴组件 第二个相反的方向。 执行器可从外壳的外部进入。 电缆具有联接到护套的近侧部分的第一端和联接到内轴组件的第二端，并且致动器致动器致动器沿第一方向旋转，从而使内轴组件卷起 电缆部分并缩回护套。

公开(公告)号：US09486350B2

公开(公告)日：2016-11-08

申请号：US14230826

申请日：2014-03-31

申请人： Medtronic Vascular, Inc.

发明人： Jeffery Argentine

IPC分类号： A61F2/966 ,  A61F2/95

CPC分类号： A61F2/966 ,  A61F2002/9517 ,  A61F2002/9665

摘要： A delivery system for a stent-graft is disclosed having a tip capture device and a tip release handle mechanism configured to actuate the tip capture device. The tip release handle mechanism includes a rotatable grip component and a tip release actuation component. The grip component may be rotatable in a first direction to transition a proximal stent of the stent-graft from the delivery state to a partially deployed state and rotatable in an opposite, second direction to transition the proximal stent from the partially deployed state to a fully deployed state. The grip component is operably coupled to the tip release actuation component. The delivery system further includes a shaft component operably coupled to the tip release actuation component and the tip capture device.

摘要翻译： 公开了一种用于支架移植物的递送系统，其具有尖端捕获装置和配置成致动尖端捕获装置的尖端释放手柄机构。 尖端释放手柄机构包括可旋转夹持部件和尖端释放致动部件。 夹持部件可以在第一方向上旋转，以将支架移植物的近端支架从输送状态转移到部分展开状态并且可沿相反的第二方向旋转，以将近端支架从部分展开状态转换到完全 部署状态。 夹持部件可操作地联接到尖端释放致动部件。 输送系统还包括可操作地联接到尖端释放致动部件和尖端捕获装置的轴部件。

公开(公告)号：US20160302912A1

公开(公告)日：2016-10-20

申请号：US14691109

申请日：2015-04-20

申请人： Medtronic Vascular, Inc.

发明人： Jeffery Argentine ,  Mark Rowe

IPC分类号： A61F2/07 ,  G01N3/12

CPC分类号： A61F2/07 ,  A61F2240/008 ,  G01N3/12 ,  G01N3/34 ,  G01N21/0332 ,  G01N21/3504 ,  G01N21/552 ,  G01N21/658 ,  G01N30/6082 ,  G01N30/74 ,  G01N2203/0007 ,  G01N2203/0037 ,  G01N2203/0073 ,  G01N2203/0089

摘要： A dilatation or fatigue tester for a stent-graft prosthesis includes a sample holder having a compressible member that defines a chamber for receiving a stent-graft prosthesis in an expanded state, a bearing assembly disposed to contact and act on an exterior surface of the compressible member of the sample holder, and an actuation assembly operably coupled to the bearing assembly for rotating the bearing assembly relative to the sample holder. Rotation of the bearing assembly cyclically compresses the compressible member of the sample holder to thereby provide cyclical radial loading and unloading of a stent-graft prosthesis received therein for simulating physiologic loading conditions of a stent-graft prosthesis within a vasculature due to a beating heart.

摘要翻译： 用于支架移植假体的扩张或疲劳测试器包括具有可压缩构件的样品保持器，所述可压缩构件限定用于接收处于膨胀状态的支架移植假体的腔室;轴承组件，其设置成接触并作用在可压缩物体的外表面上 以及可操作地联接到所述轴承组件的用于使所述轴承组件相对于所述样品架旋转的致动组件。 轴承组件的旋转循环地压缩样品保持器的可压缩构件，从而提供其中接收的支架移植假体的循环径向加载和卸载，以模拟由于跳动心脏而在脉管系统内的支架移植假体的生理负荷状况。

公开(公告)号：US09445928B2

公开(公告)日：2016-09-20

申请号：US13906079

申请日：2013-05-30

申请人： Medtronic Vascular, Inc.

发明人： Jeffery Argentine

IPC分类号： A61F2/966 ,  A61F2/95

CPC分类号： A61F2/966 ,  A61F2/844 ,  A61F2002/9517

摘要： A delivery system for delivering a prosthesis, the delivery system including a housing, a sheath extending from within the housing, a clutching mechanism housed within the housing, and a cable. The clutching mechanism includes a one-way clutch that transmits a torque from an actuator to an inner shaft assembly when the actuator is rotated in a first direction and does not transmit a torque from the actuator to the inner shaft assembly when the actuator is rotated in a second opposing direction. The actuator is accessible from an exterior of the housing. The cable has a first end coupled to a proximal portion of the sheath and a second end coupled to the inner shaft assembly, and actuation of the actuator causes the actuator to rotate in the first direction, thereby causing the inner shaft assembly to wind up a portion of cable and retract the sheath.

摘要翻译： 用于输送假体的输送系统，所述输送系统包括壳体，从所述壳体内延伸的护套，容纳在所述壳体内的收紧机构和电缆。 离合器包括单向离合器，当致动器沿着第一方向旋转时，将致动器的扭矩传递到内轴组件，并且当致动器旋转时，该单向离合器不将致动器的转矩传递到内轴组件 第二个相反的方向。 执行器可从外壳的外部进入。 电缆具有联接到护套的近侧部分的第一端和联接到内轴组件的第二端，并且致动器致动器致动器沿第一方向旋转，从而使内轴组件卷起 电缆部分并缩回护套。

公开(公告)号：US20150112418A1

公开(公告)日：2015-04-23

申请号：US14060084

申请日：2013-10-22

申请人： Medtronic Vascular, Inc.

发明人： Jeffery Argentine

IPC分类号： A61F2/86 ,  A61F2/958

CPC分类号： A61F2/86 ,  A61F2/07 ,  A61F2/958 ,  A61F2002/828 ,  A61F2250/0018 ,  A61F2250/0019 ,  A61F2250/0036 ,  A61F2250/0039 ,  A61F2250/0048

摘要： A segmented balloon expandable stent graft includes a graft material and a plurality of cylindrical stent elements coupled to the graft material. The plurality of cylindrical stent elements are plastically deformable when expanded from a radially compressed configuration to a radially expanded configuration. The plurality of cylindrical stent elements includes a first end stent element, a second end stent element, and a plurality of middle stent elements. The first and second end stent elements are independent of the plurality of middle stent elements. The first and second end stent elements are more resistant to radial expansion than the plurality of middle stent elements such that the plurality of middle stent elements plastically deform from the radially compressed configuration to the radially expanded configuration when inflated by a balloon prior the first and second end stent elements.

摘要翻译： 分段气囊可扩张支架移植物包括接枝材料和多个与移植材料连接的圆柱形支架元件。 当从径向压缩构型扩展到径向扩张构型时，多个圆柱形支架元件是塑性变形的。 多个圆柱形支架元件包括第一端支架元件，第二端支架元件和多个中间支架元件。 第一和第二端支架元件独立于多个中间支架元件。 第一和第二端支架元件比多个中间支架元件更能抵抗径向膨胀，使得当第一和第二支架元件在第一和第二支架元件膨胀之前由球囊膨胀时，多个中间支架元件从径向压缩构型塑性变形到径向膨胀构型 端支架元件。