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公开(公告)号：US4781921A
公开(公告)日：1988-11-01
申请号：US915545
申请日：1986-10-06
申请人： Daniel J. Smith , Sanjay R. Patel
发明人： Daniel J. Smith , Sanjay R. Patel
CPC分类号： C08F20/36 , A61L26/0014 , A61L26/008
摘要： Acrylate and methacrylate monoesters and diesters having the following formula (I) ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 are as defined in the specification, are disclosed. These monomers are polymerizable into hydrogel polymers which are extremely hydrophilic. These hydrogel polymers are useful in the preparation of wound dressings. These polymers form complexes with polyvalent metal ions such as Ca, Mg, Mn and Cu, and possess macrophage stimulating activity in addition to the useful properties possessed by other acrylate and methacrylate hydrogel polymers.
摘要翻译： 公开了具有下式（I）的丙烯酸酯和甲基丙烯酸酯单酯和二酯：其中R1，R2，R3如说明书中所定义。 这些单体可聚合成非常亲水的水凝胶聚合物。 这些水凝胶聚合物可用于制备伤口敷料。 这些聚合物与多价金属离子如Ca，Mg，Mn和Cu形成络合物，除了其它丙烯酸酯和甲基丙烯酸酯水凝胶聚合物具有的有用特性之外，还具有巨噬细胞刺激活性。
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公开(公告)号：US4677891A
公开(公告)日：1987-07-07
申请号：US697221
申请日：1985-01-31
CPC分类号： G10D3/146
摘要： A tremolo plate is pivotally mounted on the guitar body, and a plurality of a combination bridge saddles and lever systems are mounted on such plate, there being one such saddle-lever system for each string of the guitar. The combination systems include saddles adapted to be pivoted by set screws to change string height. They further include levers adapted to be adjusted by screws to effect fine tuning of the strings. The heads for the fine tuning screws are captured by ears. The pivot means for the tremolo plate have a pivot axis so related to the string saddles that the intonation points of the saddles may be adjusted between positions closer to the guitar neck than is such axis, and positions farther from the guitar neck than is such axis.
摘要翻译： 颤音板可枢转地安装在吉他体上，并且多个组合的桥鞍和杠杆系统被安装在这种板上，对于吉他的每一串都有一个这样的鞍座系统。 组合系统包括适于通过固定螺钉枢转以改变弦线高度的鞍座。 它们还包括适于通过螺丝调节以实现弦的微调的杠杆。 微调螺丝的头部被耳朵捕获。 用于颤音板的枢转装置具有与弦鞍相关的枢转轴线，鞍座的语调点可以在比这样的轴线更靠近吉他琴颈的位置之间进行调节，并且比该轴线更靠近吉他琴颈 。
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公开(公告)号：USD287602S
公开(公告)日：1987-01-06
申请号：US605820
申请日：1984-05-01
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公开(公告)号：USD280523S
公开(公告)日：1985-09-10
申请号：US492347
申请日：1983-05-06
申请人： Daniel J. Smith
设计人： Daniel J. Smith
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公开(公告)号：US09131936B2
公开(公告)日：2015-09-15
申请号：US13157546
申请日：2011-06-10
CPC分类号： A61B17/0401 , A61B2017/00336 , A61B2017/00805 , A61B2017/00858 , A61B2017/00907 , A61B2017/0409 , A61B2017/0461 , A61B2017/0464
摘要： A surgical device for inserting an anchor, including a handle having an actuator, an outer barrel shaft extending from the handle to a distal end and having a channel therethrough, and an outer barrel tip the distal end thereof having an elastomeric septum, a drive pin within the channel, and an implantable anchor removably coupled to the drive pin. The outer barrel shaft is coupled to an actuator for movement between a first extended position wherein the outer barrel shaft tip substantially cover the anchor, and a second retracted position where the outer barrel shaft tip do not cover the anchor. When the shaft is in the first position, the elastomeric septum of the outer barrel tip circumferentially surrounds and engages the anchor to thereby stabilize the anchor prior to deployment, and when the shaft is in the second position, the elastomeric septum does not engage the anchor.
摘要翻译： 一种用于插入锚固件的手术装置，包括具有致动器的手柄，从手柄延伸到远端并具有穿过其的通道的外筒轴，以及具有弹性体隔膜的远端，外筒末端，驱动销 以及可移动地联接到驱动销的可植入锚固件。 外筒轴联接到致动器，用于在第一延伸位置和第二缩回位置之间移动，其中外筒轴末端基本上覆盖锚固件，而第二缩回位置，外筒轴末端不覆盖锚固件。 当轴处于第一位置时，外筒尖的弹性体隔膜周向地包围并接合锚固件，从而在展开之前稳定锚，并且当轴处于第二位置时，弹性体隔膜不接合锚 。
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公开(公告)号：US09023376B2
公开(公告)日：2015-05-05
申请号：US12492507
申请日：2009-06-26
CPC分类号： A61L31/127 , A61B2090/0816 , A61F2/0063 , A61F2002/009 , A61K9/00 , A61L31/042 , A61L2400/12 , D01D5/0076 , C08L5/02 , C08L67/04
摘要： A nanofiber-reinforced composition suited to applying to a wound site in a human body includes a carrier liquid and nanofibers dispersed therein in the carrier liquid. The viscosity of the composition is such that it is able to be applied through a tube yet adhere proximate the wound site to provide a barrier layer which assists in healing of the wound by spacing it from neighboring organs.
摘要翻译： 适用于人体伤口部位的纳米纤维增强组合物包含分散在载液中的载液和纳米纤维。 组合物的粘度使得其能够通过管施加而附着在伤口部位附近以提供阻挡层，其通过将其与相邻器官隔开来辅助伤口愈合。
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公开(公告)号：US08547241B2
公开(公告)日：2013-10-01
申请号：US12969225
申请日：2010-12-15
IPC分类号： G08B21/00
摘要： An alarm unit for signaling impending overflow of a urine or ostomy (waste) bag includes an external magnet held at the end of an arm. An internal ferrous armature attracts the magnet which provides flux holding a switch element open when the magnet provides at least a predetermined flux to the switch. A clamp allows the user to fasten the unit to an edge of the waste bag with the bag walls between the magnet and the armature. When the bag contents reach the magnet, fluid force of the bag contents separates the magnet and the armature, causing the switch element to close and conduct power from a power supply to a signal element. The arm may be flexible. The switch element preferably comprises a reed switch controlling an electronic power switch.
摘要翻译： 用于指示尿液或造口术（废物）袋即将溢出的报警单元包括保持在臂末端的外部磁体。 内部铁质电枢吸引磁体，当磁体向开关提供至少一个预定磁通量时，该磁体提供保持开关元件断开的磁通。 夹具允许使用者将该单元固定在废物袋的边缘上，同时磁体和电枢之间的袋壁。 当袋内容物到达磁体时，袋内容物的流体力使磁体和电枢分离，导致开关元件闭合并将电力从电源传递到信号元件。 手臂可能是灵活的。 开关元件优选地包括控制电子电源开关的舌簧开关。
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68.发明授权Polymer no donor predrug nanofiber coating for medical devices and therapy 有权聚合物无供体前药纳米纤维涂层用于医疗器械和治疗公开(公告)号：US08298563B2
公开(公告)日：2012-10-30
申请号：US10597272
申请日：2005-01-24
申请人： Darrell Reneker , Daniel J. Smith
发明人： Darrell Reneker , Daniel J. Smith
IPC分类号： A61F2/02
CPC分类号： A61K31/78 , A61K45/06 , A61L27/34 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/114 , A61L2400/12 , A61K2300/00 , C08L79/02
摘要： The present invention relates to nanofibers that produce therapeutic amounts of nitric oxide after a delay period, which allows time to install or implant the device into a patient. The nitric oxide release is thus localized to the area of the organism where NO dosing is indicated. The delay time is achieved by cospinning the NO-producing fiber with a fiber that tends to sequester the former's NO-producing functional groups. Fibers of the present invention may be incorporated into medical devices such as stents or other implantable medical devices to prevent the formation of adhesions or scarring in the area of the implant.
摘要翻译： 本发明涉及在延迟期后产生治疗量的一氧化氮的纳米纤维，其允许将装置安装或植入患者体内的时间。 一氧化氮释放因此定位于生物体的指示NO给药的区域。 延迟时间是通过用容易隔离前者的NO产生官能团的纤维共纺生产NO的纤维实现的。 本发明的纤维可以结合到诸如支架或其它可植入医疗装置的医疗装置中，以防止在植入物区域中形成粘连或疤痕。
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公开(公告)号：US08119840B2
公开(公告)日：2012-02-21
申请号：US11817377
申请日：2006-03-03
申请人： Daniel J. Smith , Marcos Lopez
发明人： Daniel J. Smith , Marcos Lopez
IPC分类号： C07C243/02 , B05D1/00 , A61F13/00
CPC分类号： C07C291/04 , D01D5/0007 , D01F6/76
摘要： The present invention relates generally to nitric oxide releasing pharmaceutical compounds. More particularly, the present invention relates to pharmaceutical compositions that release nitric oxide under physiological conditions. In one embodiment, the present invention relates to new chemical compounds—diazeniumdiolates nitric oxide donors—that are based on ethambutol possessing physiological and biomedical activity.
摘要翻译： 本发明一般涉及一氧化氮释放药物化合物。 更具体地说，本发明涉及在生理条件下释放一氧化氮的药物组合物。 在一个实施方案中，本发明涉及基于具有生理和生物医学活性的乙胺丁醇的新的化学化合物 - 二氮烯二硫化物一氧化氮供体。
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公开(公告)号：US08042774B2
公开(公告)日：2011-10-25
申请号：US12245124
申请日：2008-10-03
IPC分类号： F16L3/22
摘要： Certain embodiments of the present invention provide a control panel mount having one or more strain relief features. The mount has a base and a tether. The tether has a first end and a second end. The first end of the tether is rotatably connected to the base. The second end of the tether is adapted to receive a cable tie.
摘要翻译： 本发明的某些实施例提供具有一个或多个应变消除特征的控制面板安装件。 安装座有一个基座和一个系绳。 系绳具有第一端和第二端。 系绳的第一端可旋转地连接到基座。 系绳的第二端适于接收电缆扎带。
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