公开(公告)号：US09381136B2

公开(公告)日：2016-07-05

申请号：US13262033

申请日：2010-04-15

申请人： Richard Cronenberg ,  Lionel Vedrine

发明人： Richard Cronenberg ,  Lionel Vedrine

IPC分类号： A61M37/00 ,  A61J1/20 ,  A61J1/06

CPC分类号： A61J1/2096 ,  A61J1/062 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2037 ,  A61J1/2072

摘要： In one aspect, a fixturing member for fixing a source of flowable material relative to a pen injector so as to permit introduction of the flowable material into the pen injector is provided herein. The fixturing member includes a body having a web with opposing proximal and distal faces. A distal wall extends distally from the distal face of the web, with the distal wall at least partially encompassing a distal chamber. Features are formed on the body for removable mounting onto a pen injector. Also, features are formed on the body for mounting onto a source of flowable material, A cannula extends through the web the cannula having proximal and distal ends with a lumen extending therebetween. The distal end of the cannula is located in the distal chamber and positioned such that, with the member being mounted to a pen injector, the distal end is located to be in the pen injector. The proximal end of the cannula is located proximally of the proximally face of the web such that, with the member being mounted to a source of flowable material, the proximal end of the cannula is located to be in communication with the flowable material. Advantageously, with the subject invention, a fixturing member is provided which facilitates mixing of substances in a pen injector in preparing a pen injector for injection.

摘要翻译： 一方面，提供了一种用于固定可流动材料源相对于笔式注射器以便允许将可流动材料引入笔式注射器的固定构件。 固定构件包括具有相对的近侧和远侧面的腹板的主体。 远端壁从腹板的远端远端延伸，远端壁至少部分地包围远侧腔室。 特征形成在主体上用于可拆卸地安装到笔式注射器上。 此外，在身体上形成用于安装到可流动材料源上的特征。套管延伸穿过腹板，套管具有近端和远端，其间延伸有内腔。 套管的远端位于远侧腔室中并且定位成使得当该构件安装到笔式注射器时，该远端位于笔式注射器中。 套管的近端位于腹板近端面的近侧，使得在该构件被安装到可流动的材料源上时，套管的近端被定位成与可流动材料连通。 有利地，在本发明中，提供了一种在制备注射用笔式注射器的同时便于在笔式注射器中混合物质的固定构件。

公开(公告)号：US08961469B2

公开(公告)日：2015-02-24

申请号：US13516540

申请日：2009-12-16

申请人： Ralph Sonderegger ,  Lionel Vedrine ,  Curt Bingham ,  Bart Peterson

发明人： Ralph Sonderegger ,  Lionel Vedrine ,  Curt Bingham ,  Bart Peterson

IPC分类号： A61M5/32 ,  A61M5/142 ,  A61M5/14

CPC分类号： A61M5/14248 ,  A61M5/14244 ,  A61M5/1626 ,  A61M5/3202 ,  A61M5/3213 ,  A61M2005/1416

摘要： A drug delivery device (100), including a body (104, 116) having a reservoir (164, 176) disposed therein for containing a medicament and an injection needle (152) for penetrating the skin of a patient, the needle (152) providing a path for the medicament between the reservoir (164, 176) and the patient. The device (100) also includes a needle cover (114) for selectively covering the injection needle (152), an adhesive (264) for selectively adhering the device to the patient, a release liner (500) for selectively covering a patient side of the adhesive (264), and a connecting means (112, 520, 512, 508, 524) for connecting the needle cover (114) and the release liner (500) such that removal of one of the needle cover (114) and the release liner (500) from the device (100) removes the other one of the needle cover (114) and the release liner (500).

摘要翻译： 一种药物输送装置（100），包括具有设置在其中的用于容纳药物的储存器（164,176）的主体（104,116）和用于穿透患者皮肤的注射针（152），所述针（152） 为储存器（164,176）和患者之间的药物提供路径。 装置（100）还包括用于选择性地覆盖注射针（152）的针罩（114），用于选择性地将装置粘附到患者的粘合剂（264），用于选择性地覆盖患者侧的剥离衬垫 粘合剂（264）和用于连接针罩（114）和释放衬垫（500）的连接装置（112,520,512,508,524），从而使针盖（114）和 脱离衬垫（500）从装置（100）移除针罩（114）和剥离衬垫（500）中的另一个。

公开(公告)号：US08490790B2

公开(公告)日：2013-07-23

申请号：US10546673

申请日：2003-02-24

申请人： Bruno Cocheteux ,  Lionel Vedrine

发明人： Bruno Cocheteux ,  Lionel Vedrine

IPC分类号： B65D83/10

CPC分类号： A61M5/008

摘要： A plate with housings for receiving objects for bulking, each housing being delimited by lateral walls and comprising a support zone for receiving the object for bulking. Each housing is formed by a cell with the lateral walls delimiting the cells adjoining one another from one cell to an adjacent cell and extending in a direction substantially perpendicular to the plane of the plate. Each cell is shaped to at least partially receive the proximal part of an object for bulking and each cell immobilizes each object for bulking.

摘要翻译： 具有用于接收用于膨胀的物体的壳体的板，每个壳体由侧壁限定，并且包括用于接收用于膨胀的物体的支撑区域。 每个壳体由细胞形成，侧壁限定细胞从一个细胞彼此相邻连接到相邻的细胞并且在基本上垂直于该平面的方向上延伸。 每个单元被成形为至少部分地接收用于膨胀的物体的近端部分，并且每个单元固定每个物体以进行膨胀。

公开(公告)号：US08444604B2

公开(公告)日：2013-05-21

申请号：US10567051

申请日：2004-08-12

申请人： Chris Cindrich ,  Ralph Sonderegger ,  Glade Howell ,  Weston Harding ,  Alex Lastovich ,  Lionel Vedrine

发明人： Chris Cindrich ,  Ralph Sonderegger ,  Glade Howell ,  Weston Harding ,  Alex Lastovich ,  Lionel Vedrine

IPC分类号： A61M5/32

CPC分类号： A61M5/158 ,  A61M5/14248 ,  A61M5/145 ,  A61M5/16804 ,  A61M2005/14256 ,  A61M2005/1426 ,  A61M2005/14506 ,  A61M2005/1583 ,  A61M2005/1585 ,  A61M2209/06

摘要： A system and method for a patch-like, self-contained substance infusion device (700) which can be attached to a skin surface via an adhesive contact surface. A push button (780) activation assembly can then be used to remove an interlock (730), allowing a disk or Belleville spring (735) assembly to apply an essentially even and constant pressure to the contents of a fluid reservoir assembly (710). This allows the release of one or more spring-loaded patient needles (760) into the skin surface, and establishes a fluid communication path between the patient needles (760) and the pressurized fluid reservoir contents thereby delivering an infusion into the skin. The push button (780) activation assembly further allows the release of one or more improved safety mechanisms (794) after use.

摘要翻译： 一种用于贴片状独立物质输注装置（700）的系统和方法，其可经由粘合剂接触表面附着于皮肤表面。 然后可以使用按钮（780）激活组件来移除互锁（730），允许盘或贝氏弹簧（735）组件对流体储存器组件（710）的内容物施加基本均匀且恒定的压力。 这允许一个或多个弹簧加载的患者针（760）释放到皮肤表面中，并且在患者针（760）和加压流体储存器内容物之间建立流体连通路径，从而将输注输送到皮肤中。 按钮（780）启动组件进一步允许在使用之后释放一个或多个改进的安全机构（794）。

公开(公告)号：US20120172793A1

公开(公告)日：2012-07-05

申请号：US13262033

申请日：2010-04-15

申请人： Richard Cronenberg ,  Lionel Vedrine

发明人： Richard Cronenberg ,  Lionel Vedrine

IPC分类号： A61M5/31 ,  B65B3/04

CPC分类号： A61J1/2096 ,  A61J1/062 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2037 ,  A61J1/2072

摘要： In one aspect, a fixturing member for fixing a source of flowable material relative to a pen injector so as to permit introduction of the flowable material into the pen injector is provided herein. The fixturing member includes a body having a web with opposing proximal and distal faces. A distal wall extends distally from the distal face of the web, with the distal wall at least partially encompassing a distal chamber. Features are formed on the body for removable mounting onto a pen injector. Also, features are formed on the body for mounting onto a source of flowable material, A cannula extends through the web the cannula having proximal and distal ends with a lumen extending therebetween. The distal end of the cannula is located in the distal chamber and positioned such that, with the member being mounted to a pen injector, the distal end is located to be in the pen injector. The proximal end of the cannula is located proximally of the proximally face of the web such that, with the member being mounted to a source of flowable material, the proximal end of the cannula is located to be in communication with the flowable material. Advantageously, with the subject invention, a fixturing member is provided which facilitates mixing of substances in a pen injector in preparing a pen injector for injection.

摘要翻译： 一方面，提供了一种用于固定可流动材料源相对于笔式注射器以便允许将可流动材料引入笔式注射器的固定构件。 固定构件包括具有相对的近侧和远侧面的腹板的主体。 远端壁从腹板的远端远端延伸，远端壁至少部分地包围远侧腔室。 特征形成在主体上用于可拆卸地安装到笔式注射器上。 此外，在身体上形成用于安装到可流动材料源上的特征。套管延伸穿过腹板，套管具有近端和远端，其间延伸有内腔。 套管的远端位于远侧腔室中并且定位成使得当该构件安装到笔式注射器时，该远端位于笔式注射器中。 套管的近端位于腹板近端面的近侧，使得在该构件被安装到可流动的材料源上时，套管的近端被定位成与可流动材料连通。 有利地，在本发明中，提供了一种在制备注射用笔式注射器的同时便于在笔式注射器中混合物质的固定构件。

公开(公告)号：US07681570B2

公开(公告)日：2010-03-23

申请号：US10529050

申请日：2003-09-26

申请人： Lionel Vedrine ,  Frederic Perot ,  Laurent Barrelle

发明人： Lionel Vedrine ,  Frederic Perot ,  Laurent Barrelle

IPC分类号： B05B7/00 ,  B05B11/00

CPC分类号： A61M5/2429 ,  A61M5/2459 ,  A61M5/315 ,  A61M5/31595 ,  A61M11/007 ,  A61M11/06 ,  A61M15/0065 ,  A61M15/08 ,  B05B11/02 ,  B05B11/025

摘要： A spray or injection device that includes a casing or a pusher that includes at least one tab configured to move radially between a first radial position in which the tab does not impede the movement of the pusher with respect to the casing, and a second radial position in which the tab opposes movement of the pusher. The tab includes an opening. The pusher or the casing, respectively, includes at least one ramp-shaped projection configured to bring the tab into the second radial position then to penetrate the opening thereby allowing the tab to return to the first radial position. The pusher or the casing, respectively, further includes at least one stop region against which the tab abuts when the tab is brought into the second radial position by the projection. The stop region occurring just before the projection being opposite the opening.

摘要翻译： 一种喷射或注射装置，其包括壳体或推动器，其包括至少一个突出部，所述突出部构造成在第一径向位置和第二径向位置之间径向移动，所述第一径向位置中突片不阻碍推动器相对于壳体的移动， 其中突片反对推动器的移动。 标签包括一个开口。 推动器或壳体分别包括至少一个斜面形突起，该突起构造成使突片进入第二径向位置，然后穿透开口，从而允许突片返回到第一径向位置。 推动器或壳体分别进一步包括至少一个止动区域，当突片通过突出部进入第二径向位置时，突出部抵靠该止挡区域。 刚好在突起之前出现的停止区域与开口相对。

公开(公告)号：US20090299325A1

公开(公告)日：2009-12-03

申请号：US12537497

申请日：2009-08-07

申请人： Lionel Vedrine ,  Paul G. Alchas ,  Christopher N. Cindrich

发明人： Lionel Vedrine ,  Paul G. Alchas ,  Christopher N. Cindrich

IPC分类号： A61J1/20

CPC分类号： A61J1/2096 ,  A61J1/1406 ,  A61J1/201 ,  A61J1/2055 ,  A61M5/1782 ,  A61M2039/042

摘要： A filling system for syringes utilizing short needles to be filled from a vial having a thick septum is described. The system may be useful in any situation where the septum or vial stopper of a medication container is thicker than the usable length of the needle on the delivery device. Preferably, the syringe is filled just prior to use. The short needle includes an optional limiter which only permits a certain predetermined length of the needle cannula to protrude beyond the limiter a distance which limits penetration of the needle tip into both the skin and a vial stopper. The system and adapter may be useful for needles having a protrusion distance from approximately 0.5 mm to 3 mm, or any needle with a protrusion length shorter that the thickness of a septum to be accessed. Furthermore, a device is provided with shielding capabilities to shield the needle of the device.

摘要翻译： 描述了从具有厚的隔膜的小瓶中填充使用短针的注射器的填充系统。 在药物容器的隔膜或药瓶塞子比输送装置上的针的可用长度更厚的任何情况下，该系统可能是有用的。 优选地，注射器在使用之前被填充。 短针包括可选的限制器，其仅允许针套管的某个预定长度突出超过限制器一定距离，该距离限制针尖进入皮肤和药瓶塞子的穿透距离。 系统和适配器对于具有大约0.5mm至3mm的突出距离的针或具有比要访问的隔膜的厚度更短的突出长度的针可能是有用的。 此外，设备具有屏蔽能力以屏蔽设备的针。

公开(公告)号：US07618401B2

公开(公告)日：2009-11-17

申请号：US10520981

申请日：2003-07-16

申请人： Lionel Vedrine

发明人： Lionel Vedrine

IPC分类号： A61M5/00

CPC分类号： A61M5/3232 ,  A61M5/2429 ,  A61M5/2459 ,  A61M5/31511

摘要： This device comprises: a body housing a hollow injection needle and a container containing the injectable product; the needle is connected to the body but able to move relative to the latter between an injection position and a retracted position; a plunger that slides in the body and is displaceable relative to the latter to perform the injection; the container is able to move relative to the plunger between a position that enables the injection to be performed and a retracted position; an arrangement for keeping the needle and the plunger in injection position, which arrangement can be released to free the needle and the plunger to move to the retracted position.

摘要翻译： 该装置包括：容纳中空注射针的主体和容纳可注射产品的容器; 针连接到主体，但能够在注射位置和缩回位置之间相对于其移动; 柱塞，其在主体中滑动并且可相对于其移动以执行注射; 容器能够相对于柱塞运动，使得能够执行注射的位置和缩回位置之间; 用于将针和柱塞保持在注射位置的布置，该布置可以被释放以使针和柱塞移动到缩回位置。

公开(公告)号：US07582073B2

公开(公告)日：2009-09-01

申请号：US12098770

申请日：2008-04-07

申请人： Laurent Barrelle ,  Lionel Vedrine ,  Paul G. Alchas

发明人： Laurent Barrelle ,  Lionel Vedrine ,  Paul G. Alchas

IPC分类号： A61M5/32

CPC分类号： A61M5/326 ,  A61M2005/3247 ,  A61M2005/3261

摘要： A medical device is provided which includes a shield system and a syringe which is coupled to the shield system. The shield system includes a syringe holder and a shield which is slidably coupled to the holder. A spring resiliently urges the shield from a retracted position to an extended position. Stop members are provided on the holder and shield for maintaining the shield in the retracted position. The syringe is slidably coupled to the holder, and extends within the shield. Axial movement of the syringe with respect to the holder causes disengagement of the stop members, allowing the spring to move the shield to the extended position. Detents are provided on the holder for maintaining the shield in the extended position.

摘要翻译： 提供了一种医疗装置，其包括屏蔽系统和联接到屏蔽系统的注射器。 屏蔽系统包括注射器保持器和可滑动地联接到保持器的护罩。 弹簧弹性地将护罩从缩回位置推向延伸位置。 止动构件设置在保持器和护罩上，用于将护罩保持在缩回位置。 注射器可滑动地联接到保持器，并且在护罩内延伸。 注射器相对于保持器的轴向运动导致止动件的脱离，允许弹簧将护罩移动到延伸位置。 在保持器上设置有用于将护罩保持在延伸位置的凹处。

公开(公告)号：US20080215015A1

公开(公告)日：2008-09-04

申请号：US10567051

申请日：2004-08-12

申请人： Chris Cindrich ,  Ralph Sonderegger ,  Glade Howell ,  Weston Harding ,  Alex Lastovich ,  Lionel Vedrine

发明人： Chris Cindrich ,  Ralph Sonderegger ,  Glade Howell ,  Weston Harding ,  Alex Lastovich ,  Lionel Vedrine

IPC分类号： A61M5/32 ,  A61M5/28

CPC分类号： A61M5/158 ,  A61M5/14248 ,  A61M5/145 ,  A61M5/16804 ,  A61M2005/14256 ,  A61M2005/1426 ,  A61M2005/14506 ,  A61M2005/1583 ,  A61M2005/1585 ,  A61M2209/06

摘要： A system and method for a patch-like, self-contained substance infusion device (700) which provides one or more substantially hidden patient needles (760) which can be placed in fluid communication with a fluid reservoir assembly (710) that includes a rigid bladder portion (712) used in conjunction with a non-distensible bladder film (740), such as a metallized film. The device (700) can be attached to a skin surface via an adhesive contact surface and a push button (780) activation assembly can then be used to remove an interlock (730), allowing a disk, or Belleville spring (735) assembly to apply an essentially even and constant pressure to the contents of a fluid reservoir assembly (710). The push button (780) activation assembly further allows the release of one or more spring-loaded patient needles (760) into the skin surface, and establishes a fluid communication path between the patient needles (760) and the pressurized fluid reservoir contents thereby delivering an infusion into the skin. The push button (780) activation assembly further allows the release of one or more improved safety mechanisms (794) after use which are driven by spring (793) and released by trap-door (790).

摘要翻译： 一种用于贴片状独立物质输注装置（700）的系统和方法，其提供一个或多个基本上隐藏的患者针（760），其可以与包括刚性的流体储存器组件（710）流体连通 与不扩张的膀胱膜（740）结合使用的气囊部分（712），例如金属化膜。 装置（700）可以经由粘合剂接触表面附接到皮肤表面，然后可以使用按钮（780）启动组件来移除互锁（730），允许盘或贝氏弹簧（735）组件 对流体储存器组件（710）的内容物施加基本均匀和恒定的压力。 按钮（780）启动组件还允许一个或多个弹簧加载的患者针（760）释放到皮肤表面中，并且在患者针（760）和加压流体储存器内容物之间建立流体连通路径，由此递送 输入皮肤。 按钮（780）启动组件进一步允许释放一个或多个改进的安全机构（794），其被使用后由弹簧（793）驱动并且由收集门（790）释放。